Ukudla kwe-Bladder Adenocarcinoma!

Isingeniso

Ukudla kwe-Bladder Adenocarcinoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ku-Bladder Adenocarcinoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza njenge-Bladder Adenocarcinoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-Bladder Adenocarcinoma?

Isibonelo, ingabe kunendaba ukuthi iCalabash yemifino idliwa kakhulu uma iqhathaniswa ne-Chicory? Ingabe kuyawenza umehluko uma izithelo zase-Asian Pear zikhethwa kune-Red Raspberry? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Common Hazelnut phezu kwe-Chestnut kanye nama-pulses afana ne-Hyacinth Bean phezu kwe-Pigeon Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Bladder Adenocarcinoma futhi ingabe iyimpendulo efanayo kuwo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Bladder Adenocarcinoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo, i-Asian Pear iqukethe izithako ezisebenzayo i-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Phloretin. Futhi okusajingijolo okubomvu kuqukethe izithako ezisebenzayo iQuercetin, Ellagic Acid, Curcumin, Formononetin, Lupeol futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa yi-Bladder Adenocarcinoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo somsoco we-Bladder Adenocarcinoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Kwe-Adenocarcinoma Yesinye?

Ukondleka komuntu siqu komdlavuza njenge-Bladder Adenocarcinoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-Bladder Adenocarcinoma, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlotshaniswa nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Bladder Adenocarcinoma

Yonke imidlavuza efana ne-Bladder Adenocarcinoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Bladder Adenocarcinoma. Izindlela ze-biochemical ezifana ne-RAS-RAF Signaling, i-mRNA Splicing, i-Oncogenic Cancer Epigenetics, i-Suppressive Histone Methylation iyingxenye yencazelo yesiginesha ye-Bladder Adenocarcinoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo kwi-Bladder Adenocarcinoma zidinga ukuqaphela izindlela ezihambisana namakhemikhali we-biochemical esigulini ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconywa nge-Bladder Adenocarcinoma lapho uthatha ukwelashwa komdlavuza I-radiation, futhi okunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-DNMT3A, TET2, ASXL1, PPM1D kanye ne-CHEK2 yizakhi zofuzo ezikleliswe phezulu ze-Bladder Adenocarcinoma. I-DNMT3A ibikwa kuma-31.8 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-TET2 ibikwa ku-12.4%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esukela kweyi-18 kuye kwengama-93. Amaphesenti angama-73.5 emininingwane yesiguli ahlonzwa njengabesilisa. Ibhayoloji ye-Bladder Adenocarcinoma kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithasiselo Zesinye i-Adenocarcinoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha imifino ye-CALABASH noma i-CHICORY?

I-Vegetable Calabash iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, i-NFKB Signaling, i-JAK-STAT Signaling kanye ne-Cell Cycle nezinye. I-Calabash inconywa nge-Bladder Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyiRadiation. Lokhu kungenxa yokuthi i-Calabash iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela woMsebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chicory yemifino yi-Quercetin, i-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezihlukene ze-biochemical ezifana Ne-Extracellular Matrix Remodelling, TGFB Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chicory ayinconywa nge-Bladder Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuwuMisebe ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-CALABASH YEMVIDANE INCONYISWA NGAPHEZU KWE-CHICORY YE-Bladder Adenocarcinoma KANYE NOKWELASHWA kwemisebe.

Khetha Isithelo RED RASPBERRY noma ASIAN PEAR?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana Nokulungisa kabusha i-Extracellular Matrix, i-NFKB Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Red Raspberry iyanconywa nge-Bladder Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation. Lokhu kungenxa yokuthi i-Red Raspberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela Wokukhishwa Kwemisebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni sase-Asian Pear yi-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress nezinye. I-Asian Pear ayinconywa nge-Bladder Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-RASPBERRY EBOMVU ESISITHELO INCONYISWA NGAPHEZU KWEPEYARI LASE-ASIA NGE-Adenocarcinoma Yesinye KANYE NOKWELAPHA Imisebe.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Curcumin, i-Formononetin, i-Lupeol, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana Nokulungisa kabusha i-Extracellular Matrix, i-NFKB Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Hazelnut evamile iyanconywa nge-Bladder Adenocarcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuwuMisebe. Lokhu kungenxa yokuthi i-Hazelnut Ejwayelekile iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela Wokukhishwa Kwemisebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Ellagic Acid, i-Curcumin, i-Formononetin, i-Lupeol, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Extracellular Matrix Remodeling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut ayinconywa nge-Bladder Adenocarcinoma uma ukwelashwa komdlavuza okuqhubekayo kuwuMisebe ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT YE-Bladder Adenocarcinoma KANYE NOKWELASHWA kwemisebe.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-Bladder Adenocarcinoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma i-RAPINI?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Protocatechuic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Apoptosis, i-PI3K-AKT-MTOR Signaling, Ukulungiswa kwe-DNA kanye ne-P53 Signaling nezinye. I-Butterbur Enkulu inconywa engozini ye-Bladder Adenocarcinoma lapho ubungozi bofuzo obuhlobene buyi-ASXL1. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Rapini yemifino yi-Apigenin, i-Curcumin, i-Lupeol, i-Protocatechuic Acid, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-DNA Repair nezinye. I-Rapini ayinconywa uma ingozi ye-Bladder Adenocarcinoma uma ingozi yofuzo ehlotshaniswa nayo i-ASXL1 ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEMVIDO INCONYISWA NGAPHEZU KWE-RAPINI NGENGOZI YOMFUZA I-ASXL1 YE-ASXLXNUMX.

Khetha isithelo NANCE noma iPUMMELO?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Protocatechuic Acid, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Apoptosis, i-PI3K-AKT-MTOR Signaling, Ukulungiswa kwe-DNA kanye ne-P53 Signaling nezinye. I-Nance inconywa engcupheni ye-Bladder Adenocarcinoma lapho ingozi yofuzo ehlotshaniswa nayo i-ASXL1. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Protocatechuic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-DNA Repair nezinye. I-Pummelo ayinconywa uma ingozi ye-Bladder Adenocarcinoma uma ingozi yofuzo ehlotshaniswa nayo i-ASXL1 ngoba yandisa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YOMKHANZA YE-ASXL1 yofuzo.

Khetha Nut BLACK WALNUT noma PILI NUT?

I-Black Walnut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives njenge-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Protocatechuic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, Cell Cycle Checkpoints, PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Black Walnut inconywa engcupheni ye-Bladder Adenocarcinoma lapho ubungozi bofuzo obuhlobene buyi-ASXL1. Lokhu kungenxa yokuthi i-Black Walnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Pili Nut yi-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Protocatechuic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-DNA Repair nezinye. I-Pili Nut ayinconywa uma ingozi ye-Bladder Adenocarcinoma uma ingozi yofuzo ehlotshaniswa nayo i-ASXL1 ngoba yandisa izindlela zayo zokusayina.

I-WALNUT EMNYAMA INCONYISWA NGAPHEZU KWE-PILI NUT NGENGOZI YOFUZO YE-ASXL1 YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Bladder Adenocarcinoma. Iziguli ze-bladder Adenocarcinoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungekona?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezehlukene zezinkomba zomdlavuza njenge-Bladder Adenocarcinoma, ngayinye enezakhi zofuzo zesimila esinokwehluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Calabash kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda kwezinhlobo ezahlukene zokwelapha ngamakhemikhali. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli I-Bladder Adenocarcinoma?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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