Ukudla kwe-Anaplastic Pleomorphic Xanthoastrocytoma!

Isingeniso

Ukudla kwe-Anaplastic Pleomorphic Xanthoastrocytoma kufanele kube okomuntu siqu kumuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukushintsha kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene maqondana nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zendlela yokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Nge-Anaplastic Pleomorphic Xanthoastrocytoma, ingabe kunendaba ukuthi imifino, izithelo, amantongomane, imbewu umuntu udlani?

Umbuzo ovame kakhulu wokondleka obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza onjenge-Anaplastic Pleomorphic Xanthoastrocytoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Anaplastic Pleomorphic Xanthoastrocytoma?

Isibonelo, ingabe kunendaba ukuthi i-Thistle yemifino idliwa kakhulu uma iqhathaniswa ne-Rocket Salad (ssp.)? Ingabe kuyawenza umehluko uma izithelo i-Malabar Plum zikhethwa kune-Quince? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Walnut phezu kwe-Macadamia Nut kanye nama-pulses afana ne-Soy Bean phezu kwe-Common Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Anaplastic Pleomorphic Xanthoastrocytoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Malabar Plum iqukethe izithako ezisebenzayo i-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Lutein, i-Beta-carotene. Futhi i-Quince iqukethe izithako ezisebenzayo i-Eugenol, i-Chlorogenic Acid, i-Linolenic Acid, i-Lutein futhi mhlawumbe nabanye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Anaplastic Pleomorphic Xanthoastrocytoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Anaplastic Pleomorphic Xanthoastrocytoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Anaplastic Pleomorphic Xanthoastrocytoma?

Ukondleka komuntu siqu komdlavuza njenge-Anaplastic Pleomorphic Xanthoastrocytoma iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Anaplastic Pleomorphic Xanthoastrocytoma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Anaplastic Pleomorphic Xanthoastrocytoma

Yonke imidlavuza efana ne-Anaplastic Pleomorphic Xanthoastrocytoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zesiginesha ze-Anaplastic Pleomorphic Xanthoastrocytoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Notch Signaling, i-RAS-RAF Signaling, i-Apoptosis, i-Cytoskeletal Dynamics ziyingxenye yencazelo yesiginesha ye-Anaplastic Pleomorphic Xanthoastrocytoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Anaplastic Pleomorphic Xanthoastrocytoma zidinga ukuqaphela izindlela ezihambisana nesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kunconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma lapho uthatha ukwelashwa komdlavuza i-Temozolomide, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-BRAF, NOTCH1, TERT kanye ne-TP63 izakhi zofuzo ezisezingeni eliphezulu ezibikiwe ze-Anaplastic Pleomorphic Xanthoastrocytoma. I-BRAF ibikwa ku-100.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-NOTCH1 ibikwa ku-50.0%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angu-50.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Anaplastic Pleomorphic Xanthoastrocytoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelelwe izindlela ze-biochemical zesiginesha zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni zaziwa futhi lokho kufanele kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Anaplastic Pleomorphic Xanthoastrocytoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha iVegetable THISTLE noma i-ROCKET SALAD (SSP.)?

I-Vegetable Thistle iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Silibinin, i-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Lutein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. Thistle inconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi iThistle iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Rocket Salad (ssp.) yi-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Linolenic Acid, i-Lutein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. I-Rocket Salad (ssp.) ayinconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ITHILE LWEMVIDANE INCONYISWA NGAPHEZU KWE-ROCKET SALAD (SSP.) YE-Anaplastic Pleomorphic Xanthoastrocytoma KANYE NOKWELASHWA I-Temozolomide.

Khetha Isithelo QUINCE noma i-MALABAR PLUM?

I-Fruit Quince iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Eugenol, i-Chlorogenic Acid, i-Linolenic Acid, i-Lutein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. I-Quince inconywa nge-Anaplastic Pleomorphic Xanthoastrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi i-Quince ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Malabar Plum yi-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Lutein, i-Beta-carotene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. I-Malabar Plum ayinconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukuthi ukwelashwa komdlavuza kube ukumelana noma kungaphenduli kahle.

ISITHELO I-QUINCE INCONYISWA NGAPHEZU KWE-MALABAR PLUM YE-Anaplastic Pleomorphic Xanthoastrocytoma KANYE NOKWELASHWA I-Temozolomide.

Khetha Nut WALNUT noma MACADAMIA NUT?

I-Walnut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Carvacrol, i-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Juglone. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. I-Walnut inconywa nge-Anaplastic Pleomorphic Xanthoastrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide. Lokhu kungenxa yokuthi i-Walnut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Temozolomide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Macadamia Nut yi-Eugenol, i-Luteolin, i-Chlorogenic Acid, i-Lutein, i-Beta-carotene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Notch Signaling nezinye. I-Macadamia Nut ayinconyelwe i-Anaplastic Pleomorphic Xanthoastrocytoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Temozolomide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT INCONYISWA NGAPHEZU KWE-MACADAMIA NUT YE-Anaplastic Pleomorphic Xanthoastrocytoma KANYE NOKWELASHWA I-Temozolomide.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo ye-Anaplastic Pleomorphic Xanthoastrocytoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha i-Vegetable CAULIFLOWER noma isipinashi se-MUSTARD?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, i-JAK-STAT Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Ukholifulawa unconywa engcupheni ye-Anaplastic Pleomorphic Xanthoastrocytoma lapho ingozi yofuzo ehlotshaniswa nayo iyi-BRAF. Lokhu kungenxa yokuthi ukholifulawa unyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zayo zokusayina.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yesipinashi yesinaphi yi-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Mustard Spinach ayinconywa uma ingozi ye-Anaplastic Pleomorphic Xanthoastrocytoma uma ingozi yofuzo ehlotshaniswa nayo i-BRAF ngoba inyusa izindlela zayo zokusayina.

I-VEGETABLE CAULIFLOWER INCONYISWA NGAPHEZU KWESIPINSHI SEMISTARD NGENGOZI YE-BRAF GENETIC YOMKHANSA.

Khetha Isithelo NANCE noma STRAWBERRY?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Myricetin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis, i-JAK-STAT Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Nance inconywa engcupheni ye-Anaplastic Pleomorphic Xanthoastrocytoma lapho ubungozi bofuzo obuhlobene kuyi-BRAF. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Strawberry yi-Curcumin, i-Ellagic Acid, i-Myricetin, i-Quercetin, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Strawberry ayinconywa uma ingozi ye-Anaplastic Pleomorphic Xanthoastrocytoma uma ingozi yofuzo ehlotshaniswa nayo iyi-BRAF ngoba inyusa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA PHEZU KWE-STRAWBERRY YE-BRAF GENETIC INGOZI YOMKHANZA.

Khetha Nut BUTTERNUT noma BRAZIL NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, i-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics ne-Apoptosis nezinye. I-Butternut inconywa engcupheni ye-Anaplastic Pleomorphic Xanthoastrocytoma lapho ubungozi bofuzo obuhlobene kuyi-BRAF. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-Brazil Nut yi-Curcumin, i-Ellagic Acid, i-Formononetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Notch Signaling, i-JAK-STAT Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-MAPK Signaling nezinye. I-Brazil Nut ayinconywa uma ingozi ye-Anaplastic Pleomorphic Xanthoastrocytoma uma ingozi yofuzo ehlotshaniswa nayo iyi-BRAF ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-BRAZIL NUT NGENGOZI YE-BRAF GENETIC YOMKHANZA.

Ekuphetheni

Ukudla Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Anaplastic Pleomorphic Xanthoastrocytoma. Iziguli ze-Anaplastic Pleomorphic Xanthoastrocytoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo enginconyelwe futhi okungenjalo?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Anaplastic Pleomorphic Xanthoastrocytoma, ngayinye ene-tumor genetics enokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana neThistle kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukene wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Anaplastic Pleomorphic Xanthoastrocytoma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-Rhamnetin ne-cirsiliol zenza i-radiosensitization kanye nokuvinjwa kwe-epithelial-mesenchymal transition (EMT) ngokucindezelwa kwe-miR-34a-mediated kwe-Notch-1 expression emigqeni yeseli yomdlavuza wamaphaphu engewona omncane.
• I-Eugenol ikhawulela inani leCancer Stem Cell ngokucekela phansi i-β-catenin nge-N-terminal Ser37 phosphorylation-an in vivo kanye nokuhlola kokuhlola kwe-in vitro.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.
• [Indlela Ye-Chlorogenic Acid Ku-Apoptotic Regulation through Notch1 Pathway in Non-small Cell Lung Carcinoma in Animal Level].
• I-Silybin-mediated inhibition ye-Notch signing yenza umsebenzi we-antitumor kumaseli e-hepatocellular carcinoma.
• I-Carvacrol Induced Programme Cell Death and Cell Cycle Ukuboshwa Kumangqamuzana Omdlavuza Wendlala Yowesilisa Ozimele we-Androgen-Independent nge-Inhibition of Notch Signaling.
• I-Brassinin ivimbela indlela yokusayina ye-STAT3 ngokushintshwa kwe-PIAS-3 ne-SOCS-3 expression futhi iqwashise i-xenograft yomdlavuza wamaphaphu womuntu kumagundane anqunu ku-paclitaxel.