Ukudla kwe-Upper Tract Urothelial Carcinoma!

Isingeniso

Ukudla kwe-Upper Tract Urothelial Carcinoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Upper tract urothelial carcinoma, uhlobo lomdlavuza oluthinta ulwelwesi lwamapheshana aphezulu ohlelo lokuchama, ludinga ukunakwa okucophelelayo mayelana nokuxilongwa, ukumila kanye nokwelashwa. Ukuhlukaniswa kwe-ICD-10 kuyasiza ekubhalweni kwayo okujwayelekile. Ukuhlelwa kwesifo kubalulekile ekunqumeni ukubikezela kanye nokwelashwa okuqondisayo, okubandakanya ukuhlinzwa futhi okungase kuhlanganise i-chemotherapy noma i-immunotherapy, kuye ngokuthuthuka komdlavuza. Imihlahlandlela evela emigwaqweni enegunya njenge-AUA (American Urological Association), i-NCCN (National Comprehensive Cancer Network), kanye ne-EAU (European Association of Urology) inikeza iziqondiso eziphelele zokuphathwa kwe-upper tract urothelial carcinoma. Le mihlahlandlela iphinde ihlanganise namasu okulandelela nawokugada ngemva kokwelashwa ukuze kuqashwe ukuphindeka. Izinga lokubikezela kanye namazinga okusinda kwe-urothelial carcinoma ephezulu iyahlukahluka, nemiphumela incike esiteji ekuxilongweni nasekuphumeleleni kokwelashwa. Ukuxilongwa kuhilela inhlanganisela yokuhlolwa komtholampilo kanye nophenyo lwe-radiological, nezimpawu ezifana ne-hematuria nobuhlungu obudala ukuhlolwa kokuqala. Ukuqonda isethulo somtholampilo se-urothelial cell carcinoma kanye nokulandela imihlahlandlela enconyiwe yabaphathi bayo kubalulekile ekuthuthukiseni ukunakekelwa kwesiguli kanye nokwenza ngcono imiphumela.

Nge-Upper Tract Urothelial Carcinoma ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokondleka obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza ofana ne-Upper Tract Urothelial Carcinoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Upper Tract Urothelial Carcinoma?

Isibonelo, ingabe kunendaba ukuthi imifino i-Kai-lan idliwa kakhulu uma iqhathaniswa ne-Sunburst Squash (i-pattypan Squash)? Ingabe kuyawenza umehluko uma izithelo zeGrapefruit zithandwa kuneSweet Rowanberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Chia phezu kweWalnut yaseJapane kanye nama-pulses afana nobhontshisi ophuzi we-Wax phezu kwe-Pigeon Pea. Futhi uma lokho engikudlayo kunendaba - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe I-Upper Tract Urothelial Carcinoma futhi ingabe impendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Upper Tract Urothelial Carcinoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Grapefruit iqukethe izithako ezisebenzayo i-Luteolin, i-Phloretin, i-Lupeol, i-Bergapten, i-Eugenol. Futhi i-Sweet Rowanberry iqukethe izithako ezisebenzayo i-Quercetin, i-Luteolin, i-Apigenin, i-Phloretin, i-Caffeine futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Upper Tract Urothelial Carcinoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Upper Tract Urothelial Carcinoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ngokwenza Umuntu Wokudla Okunomsoco We-Upper Tract Urothelial Carcinoma?

Ukondleka komuntu siqu komdlavuza njenge-Upper Tract Urothelial Carcinoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Upper Tract Urothelial Carcinoma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Upper Tract Urothelial Carcinoma

Yonke imidlavuza efana ne-Upper Tract Urothelial Carcinoma ingabonakala ngesethi ehlukile yezindlela zamakhemikhali ezinto eziphilayo - izindlela zokusayina ze-Upper Tract Urothelial Carcinoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Vitamin Metabolism, Cell Cycle, PI3K-AKT-MTOR Signaling, MAPK Signaling ziyingxenye yencazelo yesiginesha ye-Upper Tract Urothelial Carcinoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenza ngempumelelo kwe-Upper Tract Urothelial Carcinoma kudingeka kuqashelwe izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa nge-Upper Tract Urothelial Carcinoma lapho uthatha ukwelashwa komdlavuza i-Ifosfamide, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-FGFR3, KMT2D, KDM6A, TERT kanye ne-KMT2C yizakhi zofuzo ezikleliswe phezulu ze-Upper Tract Urothelial Carcinoma. I-FGFR3 ibikwa ku-10.2% weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-KMT2D ibikwa ku-7.6%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esuka ku-38 kuya ku-88. Amaphesenti angu-64.9 emininingwane yesiguli ahlonzwa njengabesilisa. I-Upper Tract Urothelial Carcinoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zokusayina ze-biochemical kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla kanye Nezithako ze-Upper Tract Urothelial Carcinoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha iVegetable KAI-LAN noma SUNBURST SQUASH (PATTYPAN SQUASH)?

I-Vegetable Kai-lan iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Apigenin, i-Phloretin, i-Caffeine, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, umjikelezo wamaseli, i-Epithelial to Mesenchymal Transition kanye ne-Cell Cycle Checkpoints nezinye. I-Kai-lan inconywa nge-Upper Tract Urothelial Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide. Lokhu kungenxa yokuthi u-Kai-lan ulungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ifosfamide.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino i-Sunburst Squash (i-pattypan Squash) yi-Luteolin, i-Apigenin, i-Myricetin, i-Phloretin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial to Mesenchymal Transition kanye ne-Oxidative Stress nezinye. I-Sunburst Squash (i-pattypan Squash) ayinconywa nge-Upper Tract Urothelial Carcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kuzwele noma kungaphenduli kahle.

I-KAI-LAN YESIBILI INCONYISWA NGAPHEZU KWE-SUNBURST SQUASH (PATTYPAN SQUASH) NGE-Upper Tract Urothelial Carcinoma KANYE NOKWELASHWA I-Ifosfamide.

Khetha Isithelo SWEET ROWANBERRY noma i-GRAPECFRUIT?

I-Fruit Sweet Rowanberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Luteolin, i-Apigenin, i-Phloretin, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, umjikelezo wamaseli, i-Epithelial to Mesenchymal Transition kanye ne-Cell Cycle Checkpoints nezinye. I-Sweet Rowanberry iyanconywa nge-Upper Tract Urothelial Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide. Lokhu kungenxa yokuthi i-Sweet Rowanberry iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Ifosfamide.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Grapefruit yi-Luteolin, i-Phloretin, i-Lupeol, i-Bergapten, i-Eugenol. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oxidative Stress nezinye. I-Grapefruit ayinconywa nge-Upper Tract Urothelial Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO EMNANDI I-ROWANBERRY INCONYISWA NGAPHEZU KWE-GRAPESIFRUIT NGE-Upper Tract Urothelial Carcinoma KANYE NOKWELASHWA I-Ifosfamide.

Khetha Nut CHIA noma JAPANESE WALNUT?

I-Chia iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Luteolin, i-Apigenin, i-Myricetin, i-Phloretin, i-Caffeine. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, Epithelial to Mesenchymal Transition, Ukulungiswa kwe-DNA kanye ne-Vitamin Metabolism nezinye. I-Chia inconywa nge-Upper Tract Urothelial Carcinoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide. Lokhu kungenxa yokuthi i-Chia ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Ifosfamide.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Walnut yaseJapane yi-Luteolin, i-Apigenin, i-Ellagic Acid, i-Myricetin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial to Mesenchymal Transition kanye ne-Oxidative Stress nezinye. I-Walnut yaseJapane ayinconywa nge-Upper Tract Urothelial Carcinoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ifosfamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-CHIA INCONYISWA NGE-WALNUT YASE-JAPANESE NGE-Upper Tract Urothelial Carcinoma KANYE NOKWELASHWA I-Ifosfamide.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-Upper Tract Urothelial Carcinoma noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha i-Vegetable CAULIFLOWER noma isipinashi?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Lupeol, i-Daidzein, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Apoptosis, i-P53 Signaling, i-MAPK Signaling kanye ne-Cell Cycle Checkpoints nezinye. Ukholifulawa unconywa engcupheni ye-Upper Tract Urothelial Carcinoma lapho ingozi yofuzo ehlotshaniswa nayo iyi-FGFR3. Lokhu kungenxa yokuthi ukholifulawa unyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zayo zokusayina.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Isipinashi yi-Apigenin, i-Curcumin, i-Quercetin, i-Myricetin, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling, i-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Isipinashi asituswa uma ubungozi be-Upper Tract Urothelial Carcinoma uma ingozi yofuzo ehlotshaniswa nayo iyi-FGFR3 ngoba inyusa izindlela zaso zesiginesha.

I-VEGETABLE CAULIFLOWER INCONYISWA NGAPHEZU KWESIPINCHI NGE-FGFR3 GENETIC RISK YOMKHANZA.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Formononetin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Apoptosis, i-P53 Signaling, i-MAPK Signaling kanye ne-Cell Cycle Checkpoints nezinye. Okusajingijolo Okubomvu kunconywa engcupheni ye-Upper Tract Urothelial Carcinoma lapho ubungozi bofuzo obuhlobene buyi-FGFR3. Lokhu kungenxa yokuthi i-Red Raspberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Formononetin, i-Lycopene. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints kanye ne-MYC Signaling nezinye. I-Pummelo ayinconywa uma ingozi ye-Upper Tract Urothelial Carcinoma uma ingozi yofuzo ehlotshaniswa nayo iyi-FGFR3 ngoba inyusa izindlela zayo zokusayina.

I-RASPBERRY EBOMVU ISITHELO INCONYISWA NGAPHEZU KWE-PUMMELO YE-FGFR3 GENETIC RISK YOMKHANZA.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Myricetin, i-Formononetin, i-Lycopene. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, P53 Signaling, MAPK Signaling kanye neCell Cycle Checkpoints nezinye. I-Hazelnut evamile inconywa engcupheni ye-Upper Tract Urothelial Carcinoma lapho ingozi yofuzo ehlotshaniswa nayo iyi-FGFR3. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Myricetin, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints kanye ne-MYC Signaling nezinye. I-Chestnut ayinconywa uma ingozi ye-Upper Tract Urothelial Carcinoma uma ingozi yofuzo ehlotshaniswa nayo iyi-FGFR3 ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT NGE-FGFR3 GENETIC RISK YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Upper Tract Urothelial Carcinoma. Iziguli kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungenjalo?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Upper Tract Urothelial Carcinoma, ngayinye enezakhi zofuzo zesimila ezihlukene ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Kai-lan kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli I-Upper Tract Urothelial Carcinoma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Access 2021
• Ingxenye engenhla ye-urothelial carcinoma inomumo we-T-cell weluminal-papillary ephelile kanye nokusayinda okucushiwe kwe-FGFR3.
• I-Retinol yehlisa amazinga e-beta-catenin amaprotheni emigqeni yamaseli omdlavuza we-colon we-retinoic acid.
• I-lipidomics esebenzayo: I-Palmitic acid ikhubaza ukuthuthukiswa kwe-hepatocellular carcinoma ngokumodela uketshezi lwe-membrane kanye ne-glucose metabolism.
• I-Phloretin icindezela i-metastasis ngokukhomba i-protease futhi ivimbele ukuqina komdlavuza kanye ne-angiogenesis kumaseli omdlavuza womlomo wesibeletho.
• I-citrus flavonoid naringenin ikhuthaza ukulungiswa kwe-DNA kumaseli omdlavuza wendlala yesinye.
• I-Brassinin ivimbela indlela yokusayina ye-STAT3 ngokushintshwa kwe-PIAS-3 ne-SOCS-3 expression futhi iqwashise i-xenograft yomdlavuza wamaphaphu womuntu kumagundane anqunu ku-paclitaxel.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.