Ukudla kwe-Systemic Mastocytosis!

Isingeniso

Ukudla kwe-Systemic Mastocytosis kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ku-Systemic Mastocytosis ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza njenge-Systemic Mastocytosis ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengeSystemic Mastocytosis?

Isibonelo, ingabe kunendaba ukuthi imifino ye-brussel sprouts idliwa kakhulu uma iqhathaniswa netheniphu? Ingabe kuyawenza umehluko uma izithelo Fig zithandwa kuneRabbiteye Blueberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Walnut Emnyama phezu kwe-Chestnut kanye nama-pulses afana neChickpea phezu kwe-Catjang Pea. Futhi uma lokho engikudlayo kunendaba - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Systemic Mastocytosis futhi ingabe iyimpendulo efanayo kuwo wonke umuntu onokuxilongwa okufanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Systemic Mastocytosis!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Fig iqukethe izithako ezisebenzayo i-Isoliquiritigenin, i-Quercetin, i-Kaempferol, i-Taxifolin, i-Curcumin. Futhi i-Rabbiteye Blueberry iqukethe izithako ezisebenzayo i-Quercetin, i-Linalool, i-Geraniol, i-Gallic Acid, i-Ferulic Acid kanye nezinye okungenzeka.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Systemic Mastocytosis - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Systemic Mastocytosis.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Adingekayo Ekwenzeni Ukudla Okunempilo Ye-Systemic Mastocytosis?

Ukondleka komuntu siqu komdlavuza njenge-Systemic Mastocytosis iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Systemic Mastocytosis biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhlobene nokwelashwa okungayeka ukusebenza ngakho.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Systemic Mastocytosis

Wonke ama-cancer afana ne-Systemic Mastocytosis angabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-Systemic Mastocytosis. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-JAK-STAT Signaling, i-MAPK Signaling, i-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling iyingxenye yencazelo yesiginesha ye-Systemic Mastocytosis. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Systemic Mastocytosis zidinga ukuqaphela izindlela zesiginesha ze-biochemical esigulini ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kunconyelwe i-Systemic Mastocytosis lapho uthatha ukwelashwa komdlavuza i-Midostaurin, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-CNOT3, DNMT3A, FLT3, NPM1 kanye ne-KIT yizakhi zofuzo ezikleliswe phezulu ze-Systemic Mastocytosis. I-CNOT3 ibikwa ku-50.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-DNMT3A ibikwa ku-50.0 %. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. I-100.0 % yemininingwane yesiguli ihlonzwa njengabesilisa. I-Systemic Mastocytosis biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical zesiginesha zalo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla kanye Nezithako ze-Systemic Mastocytosis

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha Imifino BRUSSEL sprouts noma TURNIP?

Imifino ye-Brussel Sprouts iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Isoliquiritigenin, i-Taxifolin, i-Sulforaphane, i-Curcumin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, MAPK Signaling, Oncogenic Cancer Epigenetics kanye ne-MYC Signaling nezinye. I-Brussel Sprouts inconyelwe i-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin. Lokhu kungenxa yokuthi i-Brussel Sprouts ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Midostaurin.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-turnip yemifino yi-Isoliquiritigenin, i-Quercetin, i-Kaempferol, i-Taxifolin, i-Ellagic Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling, i-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Itheniphu ayinconyelwe ku-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

AMAPHUMELA E-BRUSSEL EMIFONI KUNCONYWA PHEZU KWE-JINIKA YE-Systemic Mastocytosis KANYE NOKWELASHWA I-Midostaurin.

Khetha Isithelo i-RABITEYE BLUEBERRY noma i-FIG?

I-Fruit Rabbiteye Blueberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Linalool, i-Geraniol, i-Gallic Acid, i-Ferulic Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Rabbiteye Blueberry inconyelwa i-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin. Lokhu kungenxa yokuthi i-Rabbiteye Blueberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Midostaurin.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni Fig yi-Isoliquiritigenin, i-Quercetin, i-Kaempferol, i-Taxifolin, i-Curcumin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Fig ayinconyelwe i-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin ngoba ilungisa lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ISITHELO I-RABITEYE BLUEBERRY INCONYISWA NGAPHEZU KWE-FIG YE-Systemic Mastocytosis KANYE NOKWELASHWA I-Midostaurin.

Khetha Nut BLACK WALNUT noma CHESTNUT?

I-Walnut Emnyama iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Isoliquiritigenin, i-Myricetin, i-Quercetin, i-Kaempferol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Black Walnut inconywa nge-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin. Lokhu kungenxa yokuthi I-Walnut Emnyama ilungisa leyo migudu ye-biochemical ebikwe ngokwesayensi ukuze iqwashise umthelela we-Midostaurin.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Apigenin, i-Isoliquiritigenin, i-Myricetin, i-Kaempferol, i-Luteolin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics kanye ne-MYC Signaling nezinye. I-Chestnut ayinconyelwe ku-Systemic Mastocytosis lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Midostaurin ngoba ilungisa lezo zindlela ze-biochemical eyenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT EMNYAMA INCONYISWA NGAPHEZU KWE-CHESTNUT YE-Systemic Mastocytosis KANYE NOKWELASHWA I-Midostaurin.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo ye-Systemic Mastocytosis noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha i-Vegetable CAULIFLOWER noma i-ARROWHEAD?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Isoliquiritigenin, i-Curcumin, i-Catechol, i-Vitamin C, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. Ukholifulawa unconywa ngengozi ye-Systemic Mastocytosis lapho ubungozi bofuzo obuhlobene buyi-CNOT3. Lokhu kungenxa yokuthi ukholifulawa unyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zayo zokusayina.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Arrowhead yemifino yi-Apigenin, i-Myricetin, i-Isoliquiritigenin, i-Kaempferol, i-Luteolin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Stem Cell Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Isihloko somcibisholo asinconywa uma ingozi ye-Systemic Mastocytosis uma ingozi yofuzo ehlotshaniswa nayo iyi-CNOT3 ngoba inyusa izindlela zayo zokusayina.

I-VEGETABLE CAULIFLOWER INCONYISWA NGAPHEZU KWE-ARROWHEAD NGENGOZI YOFUZO YE-CNOT3 YOMKHANZA.

Khetha Isithelo ULEMONI noma I-PUMMELO?

I-Fruit Lemon iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Isoliquiritigenin, i-D-limonene, i-Luteolin, i-Linalool, i-Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Suppressive Histone Methylation, i-RAS-RAF Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. Ulamula unconywa ngengozi ye-Systemic Mastocytosis lapho ubungozi bofuzo obuhlobene buyi-CNOT3. Lokhu kungenxa yokuthi i-Lemon inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Quercetin, i-Isoliquiritigenin, i-Curcumin, i-Lycopene. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. I-Pummelo ayinconywa uma ingozi ye-Systemic Mastocytosis uma ingozi yofuzo ehlotshaniswa nayo iyi-CNOT3 ngoba inyusa izindlela zayo zokusayina.

ULEMON WESITHELO UYANCONYISWA PHEZU KWE-PUMMELO NGENGOZI YE-CNOT3 YOFUZO LOMKHANZA.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Myricetin, i-Isoliquiritigenin, i-Kaempferol, i-Luteolin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, i-RAS-RAF Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Butternut inconywa engcupheni ye-Systemic Mastocytosis lapho ubungozi bofuzo obuhlobene buyi-CNOT3. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yase-Europe yi-Apigenin, i-Quercetin, i-Myricetin, i-Isoliquiritigenin, i-Kaempferol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Stem Cell Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Chestnut yaseYurophu ayinconywa uma ingozi ye-Systemic Mastocytosis uma ingozi yofuzo ehlotshaniswa nayo iyi-CNOT3 ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGE-CHESTNUT YASE-EUROPE NGE-CNOT3 GENETIC RISK OF CANCER.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njenge-Systemic Mastocytosis. Iziguli ze-Systemic Mastocytosis kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithako zokudla okunconyelwe mina nezinganconyelwe?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Systemic Mastocytosis, ngayinye enezakhi zofuzo zesimila ezihlukene ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Brussel Sprouts kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda kwezinhlobo ezahlukene zokwelapha ngamakhemikhali. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Systemic Mastocytosis?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• Aml Ohsu 2018
• Imiphumela ye-isoliquiritigenin kumaseli omdlavuza wesibeletho.
• I-Gallic acid indanone kanye ne-mangiferin xanthone yizici ezinamandla zemiphumela ye-immunosuppressive anti-tumour ye-Mangifera indica L. bark kumaseli omdlavuza webele we-MDA-MB231.
• I-Sulforaphane ibangela ukucindezelwa kwe-epigenetic kwenkulumo ye-hTERT emigqeni yamaseli omdlavuza webele womuntu.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.
• I-Geraniol, ingxenye yamafutha abalulekile ezitshalo, iqwashisa amangqamuzana omdlavuza womuntu wekholoni ekwelashweni kwe-5-Fluorouracil.
• I-lipidomics esebenzayo: I-Palmitic acid ikhubaza ukuthuthukiswa kwe-hepatocellular carcinoma ngokumodela uketshezi lwe-membrane kanye ne-glucose metabolism.
• I-D-Limonene ishintsha ukuvuvukala, ukucindezeleka kwe-oxidative kanye nendlela ye-Ras-ERK yokuvimbela i-tumorigenesis yesikhumba se-murine.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.