Ukudla Komdlavuza Wamaphaphu Amaseli Amancane!

Isingeniso

Ukudla Komdlavuza Wamaphaphu Amangqamuzana Amancane kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ngomdlavuza Wamaphaphu Amangqamuzana Amancane kunendaba ukuthi imifino, izithelo, amantongomane, imbewu umuntu udlani?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza uwukuthi - kumdlavuza onjengomdlavuza wamaphaphu amangqamuzana amancane ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengoCancer Small Lung Cancer?

Isibonelo, ingabe kunendaba ukuthi ukholifulawa wemifino udliwa kakhulu uma uqhathaniswa netheniphu? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kunePomegranate? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana neButternut phezu kweCashew Nut kanye namapulses afana noBroad Bean phezu kweYardlong Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe Umdlavuza Wamaphaphu Amangqamuzana Amancane futhi ingabe impendulo efanayo yawo wonke umuntu onesimo esifanayo sokuxilonga noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba Yomdlavuza Wamaphaphu Amaseli Amancane!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Ngokwesibonelo iPummelo iqukethe izithako ezisebenzayo iQuercetin, Curcumin, Apigenin, Lycopene, Phloretin. Futhi iPomegranate iqukethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Ellagic Acid, i-Apigenin, i-Myricetin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa Umdlavuza Wamaphaphu Amangqamuzana Amancane - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla ku-Small Cell Lung Cancer.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Komdlavuza Wamaphaphu Amaseli Amancane?

Ukondleka komuntu siqu komdlavuza njengomdlavuza wamaphaphu amancane aqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji yomdlavuza wamaphaphu amancane, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelashwa komdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Small Cell Lung Cancer

Yonke imidlavuza efana Nomdlavuza Weseli Encane yamaphaphu ingabonakala ngesethi eyingqayizivele yezindlela zamakhemikhali ezinto eziphilayo - izindlela zokusayina zomdlavuza wamaphaphu amancane. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Cell Cycle, Growth Factor Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints ziyingxenye yencazelo yesiginesha ye-Small Cell Lung Cancer. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo Kumdlavuza Wamaphaphu Amangqamuzana Amancane zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezisizayo kunconyelwa Umdlavuza Wamaphaphu Omncane lapho uthatha ukwelashwa komdlavuza i-Topotecan, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TP53, i-RB1, i-RYR2, i-KMT2D ne-FAT3 yizakhi zofuzo ezikleliswe phezulu ezibikiwe zomdlavuza wamaphaphu amaseli amancane. I-TP53 ibikwa kuma-37.2 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-RB1 ibikwa ku-27.1%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esuka ku-25 kuya ku-87. Amaphesenti angu-58.0 emininingwane yesiguli ahlonzwa njengabesilisa. Ibhayoloji ye-Small Cell Lung Cancer kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako Zomdlavuza Weseli Encane Wamaphaphu

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable CAULIFLOWER noma i-TURNIP?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Phloretin, i-Lupeol, i-Isoliquiritigenin, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle, Epithelial to Mesenchymal Transition, P53 Signaling and Nutrient sensing nezinye. Ukholifulawa unconywa ku-Small Cell Lung Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan. Lokhu kungenxa yokuthi ukholifulawa uguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Topotecan.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-turnip yemifino yi-Quercetin, i-Curcumin, i-Ellagic Acid, i-Phloretin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, i-Epithelial kuya ku-Mesenchymal Transition kanye ne-WNT Beta Catenin Signaling nezinye. Itheniphu ayinconyelwe Umdlavuza Wamaphaphu Amangqamuzana Amancane uma ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-VEGETABLE CAULIFLOWER INCONYISWA PHEZU KWE-JINIKA YOMTHETHO WOKUTHOLA Umdlavuza Wamaphaphu Amaseli Amancane KANYE NOKWELASHWA I-Topotecan.

Khetha Isithelo IPOMEGRANATE noma i-PUMMELO?

Igromegranate yesithelo iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Curcumin, i-Ellagic Acid, i-Apigenin, i-Myricetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Umjikelezo Weseli, Ukusayina kwe-TGFB kanye ne-Metastasis nezinye. Ipomegranate inconywa ku-Small Cell Lung Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan. Lokhu kungenxa yokuthi iPomegranate iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Topotecan.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Quercetin, i-Curcumin, i-Apigenin, i-Lycopene, i-Phloretin. Lezi zithako ezisebenzayo zishintsha izindlela ezahlukahlukene ze-biochemical ezifana ne-DNA Repair kanye ne-WNT Beta Catenin Signaling nezinye. I-Pummelo ayinconyelwe Umdlavuza Wamaphaphu Amangqamuzana Amancane lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IPHOMEGRANATE LESITHELO KUNCONYISWA NGAPHEZU KWE-PUMMELO EMHLABENI OMncane Wamaphaphu Weseli KANYE NOKWELAPHA I-Topotecan.

Khetha Nut BUTTERNUT noma I-CASHEW NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Myricetin, i-Lycopene, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Umjikelezo Weseli, Ukusayina kwe-P53 kanye Nokusayina kwe-MAPK nokunye. I-Butternut inconywa ku-Small Cell Lung Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Topotecan.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Cashew Nut yi-Quercetin, i-Curcumin, i-Myricetin, i-Phloretin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Ukusayina kwe-MAPK kanye nokusayina kwe-MYC nokunye. I-Cashew Nut ayinconyelwe Umdlavuza Wamaphaphu Amangqamuzana Amancane lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Topotecan ngoba kushintsha lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBHUTTERNUT INCONYISWA NGAPHEZU KWENAMATI KASHEWULO LOKUTHOLA Umdlavuza Amaphaphu Amaseli Amancane KANYE NOKWELAPHA I-Topotecan.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo Lomdlavuza Wamaphaphu Omncane noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma i-ARROWROOT?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-DNA Repair kanye ne-MYC Signaling nezinye. I-Butterbur Enkulu iyanconywa ngengozi Yomdlavuza Weseli Encane Yamaphaphu lapho ingozi yofuzo ehlotshaniswa nayo i-FAT3. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Arrowroot yemifino yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Quercetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Ukusayinwa kwe-Stem Cell kanye ne-Cell Cycle Checkpoints nezinye. I-Arrowroot ayinconywa uma ingozi ye-Small Cell Lung Cancer lapho ingozi yofuzo ehlobene i-FAT3 ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYISWA NGAPHEZU KWE-ARROWROOT NGENGOZI YOFUZO YEFAT3 YOMKHANZA.

Khetha Isithelo NANCE noma i-MALUS (CRAB APPLE)?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-DNA Repair kanye ne-MYC Signaling nezinye. I-Nance inconywa ngengozi Yomdlavuza Weseli Encane Yamaphaphu lapho ingozi yofuzo ehlotshaniswa nayo i-FAT3. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Malus (i-crab Apple) yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Ukusayinwa kwe-Stem Cell kanye ne-Cell Cycle Checkpoints nezinye. I-Malus (i-crab Apple) ayituswa uma ingozi yomdlavuza wamaphaphu amancane uma ingozi yofuzo ehlotshaniswa nayo i-FAT3 ngoba yandisa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-MALUS (I-CRAB APPLE) NGENGOZI YOFUZO YEFAT3 YOMKHANZA.

Khetha Nut COMMON HAZELNUT noma CHESTNUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Daidzein, i-Quercetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, umjikelezo wamaseli, i-Angiogenesis kanye nokusayina kwe-Stem Cell nezinye. I-Hazelnut evamile inconywa engozini Yomdlavuza Wamaphaphu Amangqamuzana Amancane lapho ingozi yofuzo ehlobene i-FAT3. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Ukusayinwa kwe-Stem Cell kanye ne-Cell Cycle Checkpoints nezinye. I-Chestnut ayituswa uma ingozi Yomdlavuza Wengqamuzana Encane uma ingozi yofuzo ehlotshaniswa nayo i-FAT3 ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-CHESTNUT NGENGOZI YOFUZO YEFAT3 YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe yizinqumo ezibalulekile zomdlavuza njengomdlavuza wamaphaphu amaseli amancane. Iziguli Zomdlavuza Wamaphaphu Amancane kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunomsoco enginconyelwe zona futhi yiziphi ezinganconyelwe?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana Nomdlavuza Wamaphaphu Amangqamuzana Amancane, ngayinye inofuzo oluhlukile lwesimila esinokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana nokholifulawa kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene futhi ahlukene emizila ye-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli Umdlavuza Omaphaphu Omncane?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• Iphaphu Msk Pdx
• I-genome edidiyelwe ihlaziya ukukhomba izinguquko ezibalulekile zomshayeli we-somatic womdlavuza wamaphaphu wamangqamuzana amancane.
• Ukulungiswa kwe-DNA kanye nemisebenzi ye-redox kanye nama-inhibitors e-apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1): ukuhlaziya okuqhathanisayo kanye nobubanzi bayo kanye nemikhawulo ekuthuthukisweni kwezidakamizwa ezilwa nomdlavuza.
• I-Betulinic acid ivimbela ukuqina kanye ne-EMT yamaseli omdlavuza we-pancreatic ngokusebenza kokusayina kwe-AMPK.
• I-Gallic acid idala ukulimala kwe-DNA futhi icindezela i-DNA yokulungisa isakhi sofuzo kumaseli omdlavuza womuntu we-prostate PC-3.
• I-citrus flavonoid naringenin ikhuthaza ukulungiswa kwe-DNA kumaseli omdlavuza wendlala yesinye.
• I-Brassinin Icindezela Amathuba Okuhlaselayo Amaseli E-Carcinoma Emaphaphu Ngokuyekisa ukusebenza kwe-PI3K/Akt/mTOR Signaling Cascade.
• Ukulawulwa okungekuhle kwe-transducer yesiginali kanye ne-activator ye-transcription-3 signaling cascade nge-lupeol ivimbela ukukhula futhi yenze i-apoptosis kumaseli e-hepatocellular carcinoma.