Ukudla kwe-Polycythemia Vera!

Isingeniso

Ukudla kwe-Polycythemia Vera kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukushintsha kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Polycythemia vera iyisifo esingandile, esingapheli, esibizwa ngokuthi i-myeloproliferative neoplasm noma i-MPN. I-Polycythemia vera ibangelwa ukukhiqizwa ngokweqile kwamangqamuzana abomvu egazi (RBCs) emnkantsheni, kanye nokukhiqizwa ngokweqile kwamangqamuzana egazi amhlophe namaplatelet. Sithinta abesilisa abaningi kancane kunabesifazane futhi kwenzeka kaningi kubantu abangaphezu kweminyaka engama-60 ubudala. Abantu abane-polycythemia vera banenani eliphezulu ngokungavamile lama-RBC ajikelezayo egazini labo, okwenza igazi lijiye futhi lenyuke nevolumu (isimo esibizwa nge-hyperviscosity). Igazi elijiyile lingase lingagelezi kahle emithanjeni yegazi emincane (ama-capillaries). Uhlu lwezimpawu lungenzeka kubantu abane-polycythemia vera kuhlanganise nezimpawu ezingaqondile ezifana nobuhlungu bekhanda, ukukhathala, ubuthakathaka, isiyezi, isikhumba esilumayo; i-spleen ekhulisiwe (splenomegaly); izinkinga ezihlukahlukene ze-gastrointestinal; kanye nengozi enkulu yokwakheka kwehlule legazi, okungase kuvimbele ukugeleza kwegazi ezithweni ezibalulekile. Bangaphezu kuka-90% abantu abane-polycythemia vera abanoguquko kufuzo lwe-JAK2. Ukwelashwa kwe-polycythemia vera kuhloswe ngayo ukunciphisa amazinga amangqamuzana abomvu egazi kanye nokuvimbela izinkinga ikakhulukazi zokwakheka kwehlule legazi (thrombosis). Izinketho zokwelapha zihlanganisa i-phlebotomy (ukukhipha igazi ngezikhathi ezithile) ukunciphisa umthamo wama-RBC ajikelezayo ukuze igazi ligeleze kahle. Iziguli ziphinde zelashwe ngemithi ye-myelosuppressive efana ne-hydroxyurea ne-busulfan, ecindezela ukwakheka kwamangqamuzana egazi emnkantsheni. Kukhona ukwelapha okwengeziwe okufana ne-aspirin yomthamo ophansi kanye nomuthi osanda kuvunywa oqondiswe ku-enzyme ye-JAK2 etholakala isebenza ngempumelelo. Ukwengeza, ukunakekelwa okusekelayo okunomsoco ofanele (ukudla kanye nezithako zemvelo) ezinama-bioactives ngokwemvelo ukuze kulungiswe izindlela ezibangela isifo kungasiza ekuthuthukiseni inhlalakahle yesiguli.

Ku-Polycythemia Vera, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokondleka obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza onjengePolycythemia Vera ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengePolycythemia Vera?

Isibonelo, ingabe kunendaba ukuthi iParsnip yemifino idliwa kakhulu uma iqhathaniswa ne-Common Beet? Ingabe kuyawenza umehluko uma isithelo esithi Black Elderberry sithandwa kuneBlack Mulberry? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Black Walnut phezu kwe-European Chestnut kanye nama-pulses afana ne-Alfalfa phezu kwe-Yellow Wax Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Polycythemia Vera futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ubungozi bofuzo?

Yebo! Ukudla okudlayo kuyindaba yePolycythemia Vera!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Black Elderberry iqukethe izithako ezisebenzayo i-Formononetin, i-Phloretin, i-Apigenin, i-Quercetin, i-Stigmasterol. Futhi I-Black Mulberry iqukethe izithako ezisebenzayo i-Formononetin, i-Phloretin, i-Apigenin, i-Quercetin, i-Stigmasterol kanye nezinye okungenzeka.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa i-Polycythemia Vera - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwePolycythemia Vera.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Adingekayo Ekwenzeni Ukudla Okungokwakho Kwe-Polycythemia Vera?

Ukondleka komuntu siqu komdlavuza njengePolycythemia Vera kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Polycythemia Vera biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Polycythemia Vera

Yonke imidlavuza efana ne-Polycythemia Vera ingabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-Polycythemia Vera. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-RAS-RAF Signaling, Cytokine Signaling, JAK-STAT Signaling, Hematopoiesis ziyingxenye yencazelo yesiginesha ye-Polycythemia Vera. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Polycythemia Vera zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithasiselo kunconywa i-Polycythemia Vera lapho uthatha ukwelashwa komdlavuza i-Ruxolitinib, futhi okunye ukudla nezithako zokudla akunconyiwe.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-JAK2, TET2, DNMT3A, SH2B3 kanye ne-ARID2 izakhi zofuzo ezikleliswe phezulu ze-Polycythemia Vera. I-JAK2 ibikwa kuma-76.5 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-TET2 ibikwa ku-21.6%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angu-0.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Polycythemia Vera biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zePolycythemia Vera

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable PARSNIP noma i-COMMON BEET?

I-Vegetable Parsnip iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Phloretin, i-Quercetin, i-Stigmasterol, i-Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, i-MAPK Signaling, i-Cytokine Signaling kanye ne-MYC Signaling nezinye. I-Parsnip inconywa nge-Polycythemia Vera lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib. Lokhu kungenxa yokuthi i-Parsnip ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ruxolitinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Common Beet yi-Formononetin, i-Phloretin, i-Apigenin, i-Stigmasterol, i-Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Common Beet ayinconyelwe i-Polycythemia Vera uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-VEGETABLE PARSNIP INCONYISWA NGAPHEZU KWE-BEET EJWAYELEKILE I-Polycythemia Vera KANYE NOKWELASHWA I-Ruxolitinib.

Khetha Isithelo EMNYAMA MULBERRY noma EMNYAMA ELDERBERRY?

I-Fruit Black Mulberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Phloretin, i-Apigenin, i-Quercetin, i-Stigmasterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, Hypoxia, MAPK Signaling kanye ne-MYC Signaling nezinye. I-Black Mulberry inconywa nge-Polycythemia Vera lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib. Lokhu kungenxa yokuthi uMulberry Omnyama uguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ruxolitinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni esithi Black Elderberry yiFormononetin, Phloretin, Apigenin, Quercetin, Stigmasterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Black Elderberry ayinconyelwe i-Polycythemia Vera uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib ngoba ilungisa lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-FRUIT BLACK MulBERRY INCONYISWA NGAPHEZU KWE-BLACK ELDERBERRY YE-Polycythemia Vera KANYE NOKWELASHWA I-Ruxolitinib.

Khetha Nut BLACK WALNUT noma EUROPEAN CHESTNUT?

I-Walnut Emnyama iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Phloretin, i-Apigenin, i-Quercetin, i-Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-RAS-RAF Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Black Walnut inconywa nge-Polycythemia Vera lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib. Lokhu kungenxa yokuthi I-Walnut Emnyama ilungisa leyo migudu ye-biochemical ebikwe ngokwesayensi ukuze iqwashise umthelela we-Ruxolitinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-European Chestnut yi-Formononetin, i-Phloretin, i-Apigenin, i-Quercetin, i-Stigmasterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Chestnut yase-Europe ayinconyelwe i-Polycythemia Vera uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ruxolitinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT EMNYAMA INCONYISWA NGE-CHESTNUT YASE-EUROPE NGE-Polycythemia Vera KANYE NOKWELASHWA I-Ruxolitinib.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-Polycythemia Vera noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha i-Vegetable CAULIFLOWER noma i-KOHLRABI?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Formononetin, i-Bergapten, i-Isoliquiritigenin, i-Catechol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Chemokine Signaling, i-RAS-RAF Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-MYC Signaling nezinye. Ukholifulawa unconywa engcupheni ye-Polycythemia Vera uma ingozi yofuzo ehambisana nayo iyi-ARID2. Lokhu kungenxa yokuthi ukholifulawa unyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zayo zokusayina.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Kohlrabi yi-Quercetin, i-Curcumin, i-Formononetin, i-Bergapten, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling kanye ne-Hematopoiesis nezinye. I-Kohlrabi ayinconywa uma ingozi ye-Polycythemia Vera uma ingozi yofuzo ehlotshaniswa nayo i-ARID2 ngoba yandisa izindlela zayo zokusayina.

I-VEGETABLE CAULIFLOWER INCONYISWA NGE-KOHLRABI NGENGOZI YOFUZO YE-ARID2 YOMKHANZA.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Ellagic Acid, i-Curcumin, i-Formononetin, i-Bergapten. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling, i-RAS-RAF Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-Hematopoiesis nezinye. Okusajingijolo Okubomvu Kunconywa engcupheni ye-Polycythemia Vera lapho ubungozi bofuzo obuhlobene buyi-ARID2. Lokhu kungenxa yokuthi i-Red Raspberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Quercetin, i-Curcumin, i-Apigenin, i-Formononetin, i-Bergapten. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling kanye ne-Hematopoiesis nezinye. I-Pummelo ayinconywa uma ingozi ye-Polycythemia Vera uma ingozi yofuzo ehlotshaniswa nayo iyi-ARID2 ngoba inyusa izindlela zayo zokusayina.

IFRUIT RED RASPBERRY INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YOFUZO YE-ARID2 YOMKHANZA.

Khetha Nut BUTTERNUT noma I-CASHEW NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Myricetin, i-Apigenin, i-Formononetin, i-Bergapten. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling, i-MYC Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-Hematopoiesis nezinye. I-Butternut inconywa engcupheni ye-Polycythemia Vera uma ingozi yofuzo ehlotshaniswa nayo iyi-ARID2. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Cashew Nut yi-Quercetin, i-Curcumin, i-Myricetin, i-Formononetin, i-Bergapten. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-PI3K-AKT-MTOR Signaling, i-Oncogenic Cancer Epigenetics kanye ne-MYC Signaling nezinye. I-Cashew Nut ayinconywa uma ingozi ye-Polycythemia Vera uma ingozi yofuzo ehlotshaniswa nayo iyi-ARID2 ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA PHEZU KWE-CASHEW Nuthi NGENGOZI YOFUZO YE-ARID2 YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njengePolycythemia Vera. Iziguli ze-Polycythemia Vera kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Polycythemia Vera, ngayinye enezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Parsnip kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo sokwenza kube ngokwakho umsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Polycythemia Vera?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Pancan Pcawg 2020
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• Inqubekelaphambili yocwaningo emiphumeleni yokulwa nomdlavuza kavithamini K2.
• I-lipidomics esebenzayo: I-Palmitic acid ikhubaza ukuthuthukiswa kwe-hepatocellular carcinoma ngokumodela uketshezi lwe-membrane kanye ne-glucose metabolism.
• I-Formononetin-induced oxidative stress iqeda ukwenziwa kusebenze kwe-STAT3/5 signing axis futhi icindezela ukukhula kwesimila kumodeli ye-myeloma preclinical eminingi.
• I-Imperatorin icindezela ukwanda kanye ne-angiogenesis yeseli yomdlavuza wekoloni lomuntu ngokukhomba i-HIF-1α nge-mTOR/p70S6K/4E-BP1 kanye ne-MAPK izindlela.
• Izingxenye ezithile zejusi yepomegranate njengama-inhibitors angaba khona we-prostate cancer metastasis.
• https://www.lls.org/sites/default/files/file_assets/FS13_PolycythemiaVera_FactSheet_final5.1.15.pdf
• https://rarediseases.org/rare-diseases/polycythemia-vera