Ukudla kwePheochromocytoma kanye neParaganglioma!

Isingeniso

Ukudla kwe-Pheochromocytoma Ne-Paraganglioma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ku-Pheochromocytoma Kanye Ne-Paraganglioma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokondleka obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza onjengePheochromocytoma kanye neParaganglioma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengePheochromocytoma kanye neParaganglioma?

Isibonelo, ingabe kunendaba uma i-Butterbur yemifino idliwa kakhulu uma iqhathaniswa netheniphu? Ingabe kuyawenza umehluko uma isithelo I-Sweet Orange sikhethwa kune-Rabbiteye Blueberry? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-Macadamia Nut kanye nama-pulses afana ne-Gram Bean phezu kwe-Mung Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Pheochromocytoma kanye ne-Paraganglioma futhi ingabe impendulo efanayo yawo wonke umuntu one-diagnosis efanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba yePheochromocytoma kanye neParaganglioma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Sweet Orange iqukethe izithako ezisebenzayo i-Luteolin, i-Phloretin, i-Bergapten, i-Cinnamaldehyde, i-Lupeol. Futhi i-Rabbiteye Blueberry iqukethe izithako ezisebenzayo i-Quercetin, i-Eugenol, i-Geraniol, i-Gallic Acid, i-Ferulic Acid futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Pheochromocytoma And Paraganglioma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwePheochromocytoma NeParaganglioma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Adingekayo Ekwenzeni Ukudla Okungokwakho Kwe-Pheochromocytoma Ne-Paraganglioma?

Ukondleka komuntu siqu komdlavuza njengePheochromocytoma Futhi iParaganglioma iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Pheochromocytoma kanye ne-Paraganglioma biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njengePheochromocytoma kanye neParaganglioma

Yonke imidlavuza efana nePheochromocytoma kanye neParaganglioma ingabonakala ngesethi eyingqayizivele yezindlela zamakhemikhali ezinto eziphilayo - izindlela zokusayina zePheochromocytoma kanye neParaganglioma. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Vitamin Metabolism, Izindawo Zokuhlola I-Cell Cycle, I-Small Molecule Transport, Ukuguqulwa Kokuhumusha Okuthunyelwe kuyingxenye yencazelo yesiginesha ye-Pheochromocytoma Ne-Paraganglioma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenzayo kwe-Pheochromocytoma kanye ne-Paraganglioma kudingeka kuqashelwe izindlela ezihambisana nesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezisizayo kunconyelwa i-Pheochromocytoma Kanye neParaganglioma lapho uthatha ukwelashwa komdlavuza i-Cyclophosphamide, kanti okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-EPAS1, AWAT1, POLR1A, ATRX kanye ne-ACER2 yizakhi zofuzo ezisezingeni eliphezulu ezibikwayo ze-Pheochromocytoma And Paraganglioma. I-EPAS1 ibikwa ku-6.5 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-AWAT1 ibikwa ku-3.2%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esukela kweyi-19 kuye kwengama-83. Amaphesenti angama-45.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Pheochromocytoma kanye ne-Paraganglioma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zokusayina ze-biochemical kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zePheochromocytoma kanye neParaganglioma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha I-Vegetable GIANT BUTTERBUR noma i-TURNIP?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, Epithelial to Mesenchymal Transition, Vitamin Metabolism kanye ne-MAPK Signaling nezinye. I-Butterbur Enkulu iyanconywa nge-Pheochromocytoma Kanye Ne-Paraganglioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide. Lokhu kungenxa yokuthi i-Butterbur Enkulu iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Cyclophosphamide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-turnip yemifino yi-Quercetin, i-Ellagic Acid, i-Phloretin, i-Cinnamaldehyde, i-Bergapten. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA kanye ne-Epithelial to Mesenchymal Transition nezinye. Itheniphu ayinconyelwe i-Pheochromocytoma Kanye Ne-Paraganglioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBUTTERBUR ENKULU YEZINJINI INCONYWA NGENXA YOKUJIKELA I-Pheochromocytoma Ne-Paraganglioma KANYE NOKWELASHWA I-Cyclophosphamide.

Khetha Isithelo i-RABITEYE BLUEBERRY noma i-SWEET ORANGE?

I-Fruit Rabbiteye Blueberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Eugenol, i-Geraniol, i-Gallic Acid, i-Ferulic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokulungiswa kwe-DNA, Umjikelezo Weseli, Ukusayinda kwe-MAPK nama-Cell Cycle Checkpoints nokunye. I-Rabbiteye Blueberry inconyelwa i-Pheochromocytoma Kanye neParaganglioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide. Lokhu kungenxa yokuthi i-Rabbiteye Blueberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Cyclophosphamide.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Sweet Orange yi-Luteolin, i-Phloretin, i-Bergapten, i-Cinnamaldehyde, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Cell Cycle Checkpoints nezinye. I-Orange Emnandi ayinconyelwe i-Pheochromocytoma Kanye Ne-Paraganglioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

ISITHELO I-RABITEYE BLUEBERRY INCONYISWA NGAPHEZU KWE-orange ELIMNANDI NGE-Pheochromocytoma Ne-Paraganglioma KANYE NOKWELASHWA I-Cyclophosphamide.

Khetha Nut BUTTERNUT noma MACADAMIA NUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-Vitamin Metabolism, Ukulungiswa kwe-DNA kanye ne-Epithelial kuya ku-Mesenchymal Transition nezinye. I-Butternut inconywa nge-Pheochromocytoma Kanye neParaganglioma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Cyclophosphamide.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Macadamia Nut yi-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling nezinye. I-Macadamia Nut ayinconyelwe i-Pheochromocytoma kanye ne-Paraganglioma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Cyclophosphamide ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBUTTERNUT INCONYISWA NGAPHEZU KWE-MACADAMIA NUT YE-Pheochromocytoma Kanye Ne-Paraganglioma KANYE NOKWELASHWA I-Cyclophosphamide.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-Pheochromocytoma kanye ne-Paraganglioma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GARDEN CRESS noma iROMAINE LETTUCE?

I-Vegetable Garden Cress iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Beta-sitosterol, i-Formononetin, i-Vitamin C. Lezi zithako ezisebenzayo zilawula izindlela ezihlukahlukene ze-biochemical ezifana ne-TGFB Signaling, P53 Signaling, Cell Cycle Checkpoints kanye ne-MYC Signaling nezinye. I-Garden Cress inconyelwa engcupheni ye-Pheochromocytoma Kanye Ne-Paraganglioma lapho ubungozi bofuzo obuhlobene buyi-ACER2. Lokhu kungenxa yokuthi i-Garden Cress inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli besiginesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Romaine Lettuce yi-Curcumin, i-Apigenin, i-Lupeol, i-Resveratrol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Lipid Metabolism ne-P53 Signaling nezinye. I-Romaine Lettuce ayinconywa uma ingozi ye-Pheochromocytoma Kanye ne-Paraganglioma lapho ingozi yofuzo ehlotshaniswa nayo ingu-ACER2 ngoba inyusa izindlela zayo zokusayina.

I-VEGETABLE GARDEN CRESS INCONYISWA NGAPHEZU KWE-ROMAINE LETTUCE YE-ACER2 GENETIC RISK OF CANCER.

Khetha Isithelo EMNYAMA CROWBERRY noma GRAPEFRUIT?

I-Fruit Black Crowberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling, Hypoxia, P53 Signaling and Post Translation Modification nezinye. I-Black Crowberry inconywa engcupheni ye-Pheochromocytoma Kanye ne-Paraganglioma lapho ubungozi bofuzo obuhlobene buyi-ACER2. Lokhu kungenxa yokuthi iBlack Crowberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni I-Grapefruit yi-Curcumin, i-Lupeol, i-Lycopene, i-Formononetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling ne-Lipid Metabolism nezinye. I-Grapefruit ayinconywa uma ubungozi be-Pheochromocytoma Kanye ne-Paraganglioma uma ubungozi bofuzo obuhlobene buyi-ACER2 ngoba inyusa izindlela zayo zokusayina.

I-FRUIT BLACK CROWBERRY INCONYISWA NGAPHEZU KWEGRAPEFRUIT NGE-ACER2 GENETIC RISK OF CANCER.

Khetha Nut CHIA noma HICKORY NUT?

I-Chia iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Lycopene, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-TGFB Signaling, Hypoxia, P53 Signaling kanye ne-MYC Signaling nezinye. I-Chia inconyelwe engcupheni ye-Pheochromocytoma Kanye ne-Paraganglioma lapho ubungozi bofuzo obuhlobene buyi-ACER2. Lokhu kungenxa yokuthi i-Chia inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Hickory Nut yi-Curcumin, i-Apigenin, i-Lupeol, i-Lycopene, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Lipid Metabolism kanye ne-Cell Cycle Checkpoints nezinye. I-Hickory Nut ayinconywa uma ubungozi be-Pheochromocytoma Kanye Ne-Paraganglioma lapho ubungozi bofuzo obuhlobene buyi-ACER2 ngoba kwandisa izindlela zokusayina.

I-CHIA INCONYWA NGENXA YE-HICKORY NUT NGENGOZI YOMDLALO YE-ACER2.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njengePheochromocytoma kanye neParaganglioma. I-Pheochromocytoma kanye ne-Paraganglioma iziguli kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungekona?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Pheochromocytoma kanye ne-Paraganglioma, ngayinye inofuzo oluhlukile lwesimila esinokwehlukahlukana kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Giant Butterbur kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Pheochromocytoma And Paraganglioma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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