Ukudla Okunomdlavuza Womlomo Wesibeletho!

Isingeniso

Ukudla Komdlavuza Womlomo Wesibeletho Omunyayo kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene maqondana nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zendlela yokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ngomdlavuza Womlomo Wesibeletho, ingabe kunendaba ukuthi umuntu udlani imifino, izithelo, amantongomane, imbewu?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - komdlavuza ofana Nomdlavuza Wesibeletho Mucinous ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengoCancer Mucinous Cervical Cancer?

Isibonelo, ingabe kunendaba ukuthi imifino ye-brussel sprouts idliwa kakhulu uma iqhathaniswa ne-Malabar Spinach? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneLemon? Futhi uma ukukhetha okufanayo kwenzelwe amantongomane/imbewu efana ne-Walnut Emnyama phezu kwe-Chestnut kanye nama-pulses afana ne-Black-eyed Pea phezu kwe-{food_pulse1_nr1}. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe Umdlavuza Womlomo Wesibeletho futhi ingabe impendulo efanayo kuwo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba Yomdlavuza Womlomo Wesibeletho!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Pummelo iqukethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Protocatechuic Acid, i-Lycopene, i-Lupeol. Futhi ulamula uqukethe izithako ezisebenzayo D-limonene, Linalool, Curcumin, Protocatechuic Acid, Glucaric Acid kanye nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Mucinous Cervical Cancer - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla okunomsoco ku-Mucinous Cervical Cancer.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Komdlavuza Womlomo Wesibeletho?

Ukondleka komuntu siqu komdlavuza njengomdlavuza we-Cervical Mucinous kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Mucinous Cervical Cancer biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Mucinous Cervical Cancer

Yonke imidlavuza efana ne-Mucinous Cervical Cancer ingabonakala ngesethi ehlukile yezindlela zamakhemikhali ezinto eziphilayo - izindlela zokusayina ze-Mucinous Cervical Cancer. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-RAS-RAF Signaling, MAPK Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints ziyingxenye yencazelo yesiginesha ye-Mucinous Cervical Cancer. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenza ngempumelelo ku-Mucinous Cervical Cancer kumele kuqashelwe izindlela ezihambisana namakhemikhali amakhemikhali esiguli ngasinye kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla kanye nezithako zokudla kuyanconywa ku-Mucinous Cervical Cancer lapho uthatha ukwelashwa komdlavuza I-radiation, kanti okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-KRAS, NSD1, PTCH1, RB1 kanye ne-STK11 yizakhi zofuzo ezikleliswe phezulu zomdlavuza womlomo wesibeletho. I-KRAS ibikwa ku-50.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-NSD1 ibikwa ku-50.0%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. Amaphesenti angu-0.0 emininingwane yesiguli ahlonzwa njengabesilisa. I-Mucinous Cervical Cancer biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla kanye Nezithasiselo Zomdlavuza Womlomo Wesibeletho Omuncibilikayo

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha Imifino ye-BRUSSEL sprouts noma i-MALABAR SPINACH?

Imifino ye-Brussel Sprouts iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Protocatechuic Acid, i-Glucaric Acid, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, MYC Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Brussel Sprouts inconywa ngomdlavuza womlomo wesibeletho uma ukwelapha umdlavuza okuqhubekayo kuyiRadiation. Lokhu kungenxa yokuthi i-Brussel Sprouts iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela woMsebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino i-Malabar Spinach yi-Apigenin, i-Curcumin, i-Protocatechuic Acid, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Malabar Spinach ayinconyelwe Umdlavuza Womlomo Wesibeletho uma ukwelashwa komdlavuza okuqhubekayo kuwuMisebe ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

AMAPHUMELA E-BRUSSEL EZIMBILI KUNCONYISWA NGAPHEZU KWE-MALABAR ISIPINCHI SOKUTHOLA Umdlavuza Womlomo Wesibeletho Onama-Mucinous Cervical Cancer KANYE NoKWELAPHA Imisebe.

Khetha Isithelo ULEMONI noma I-PUMMELO?

I-Fruit Lemon iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-D-limonene, i-Linalool, i-Curcumin, i-Protocatechuic Acid, i-Glucaric Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling, MYC Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Ulamula uyatuswa kumdlavuza womlomo wesibeletho uma ukwelapha umdlavuza oqhubekayo kuwuMisebe. Lokhu kungenxa yokuthi ulamula uguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela woMsebe.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Curcumin, i-Apigenin, i-Protocatechuic Acid, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Pummelo ayinconywa kumdlavuza womlomo wesibeletho uma ukwelashwa komdlavuza okuqhubekayo kuyiRadiation ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

Ulamula WESITHELO UYANCONYISWA NGAPHEZU KWE-PUMMELO EMHLABENI Womdlavuza Womlomo Wesibeletho Onama-Mucinous FUTHI NOKULAPHA Imisebe.

Khetha Nut BLACK WALNUT noma CHESTNUT?

I-Black Walnut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Protocatechuic Acid, i-Ellagic Acid, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Black Walnut inconywa ku-Mucinous Cervical Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Radiation. Lokhu kungenxa yokuthi i-Black Walnut ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela Wokukhishwa Kwemisebe.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Chestnut yi-Apigenin, i-Curcumin, i-Protocatechuic Acid, i-Lycopene, i-Ellagic Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Chestnut ayinconyelwe Umdlavuza Womlomo Wesibeletho uma ukwelashwa komdlavuza okuqhubekayo kuwuMisebe ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-WALNUT EMNYAMA INCONYISWA NGAPHEZU KWE-CHESTNUT Ngomdlavuza Womlomo Wesibeletho Onama-mucinous KANYE NoKWELAPHA Imisebe.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo Yomdlavuza Womlomo Wesibeletho noma umlando womndeni uthi "Yini Okufanele Ngidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma IBATA?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Delphinidin, i-Lupeol, i-Myricetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling kanye ne-Oxidative Stress nezinye. I-Butterbur Enkulu inconywa engozini Yomdlavuza Womlomo Wesibeletho uma ingozi yofuzo ehambisana nayo i-KRAS. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Potato yemifino yi-Quercetin, i-Curcumin, i-Delphinidin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress nezinye. Izambane alituswa uma ingozi Yomdlavuza Womlomo Wesibeletho ehlobene uma ingozi yofuzo ehlotshaniswa nayo kuyi-KRAS ngoba yandisa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYISWA NGAPHEZU KWEZAMBATO NGENGOZI YOFUZO YOMFUZA KA-KRAS.

Khetha Isithelo NANCE noma i-ACEROLA?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Delphinidin, i-Lupeol, i-Myricetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling kanye ne-Oxidative Stress nezinye. I-Nance ituswa ukuba sengozini Yomdlavuza Womlomo Wesibeletho uma ingozi yofuzo ehambisana nayo i-KRAS. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Acerola yi-Quercetin, i-Curcumin, i-Apigenin, i-Delphinidin, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Stem Cell Signaling kanye ne-Oxidative Stress nezinye. I-Acerola ayinconywa uma ubungozi boMhlaza Womlomo Wesibeletho Womucu lapho ingozi yofuzo ehlotshaniswa nayo kuyi-KRAS ngoba yandisa izindlela zayo zokusayina.

ISITHELO NANCE KUNCONYISWA NGE-ACEROLA NGENGOZI YOMDLALO YE-KRAS.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Delphinidin, i-Lupeol, i-Myricetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR Signaling, i-RAS-RAF Signaling kanye ne-Oxidative Stress nezinye. I-Butternut inconywa ngengozi Yomdlavuza Womlomo Wesibeletho uma ingozi yofuzo ehambisana nayo i-KRAS. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives e-European Chestnut yi-Ellagic Acid, Quercetin, Curcumin, Apigenin, Delphinidin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Stem Cell Signaling kanye ne-Oxidative Stress nezinye. I-Chestnut yase-Europe ayituswa uma ubungozi be-Mucinous Cervical Cancer uma ingozi yofuzo ehlotshaniswa nayo kuyi-KRAS ngoba yandisa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT YASE-EUROPE NGENGOZI YOFUZO YE-KRAS YOMDLALO.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe yizinqumo ezibalulekile zomdlavuza njengomdlavuza we-Cervical Mucinous. Iziguli ezinomdlavuza womlomo wesibeletho we-Mucinous kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana Nomdlavuza Womlomo Wesibeletho, ngasinye sinezakhi zofuzo zesimila esinokwehlukahlukana kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Brussel Sprouts kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli Umdlavuza Womlomo Wesibeletho?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• I-Daidzein icindezela i-tumor necrosis factor-α ukufuduka nokuhlasela ngokuvimbela ukusayina kwe-hedgehog/Gli1 kumaseli omdlavuza webele womuntu.
• I-D-Limonene ishintsha ukuvuvukala, ukucindezeleka kwe-oxidative kanye nendlela ye-Ras-ERK yokuvimbela i-tumorigenesis yesikhumba se-murine.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.
• Ukulawulwa okungekuhle kwe-transducer yesiginali kanye ne-activator ye-transcription-3 signaling cascade nge-lupeol ivimbela ukukhula futhi yenze i-apoptosis kumaseli e-hepatocellular carcinoma.