Ukudla kwe-Melanoma!

Isingeniso

Ukudla kwe-melanoma kufanele kube okomuntu siqu kumuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene maqondana nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zendlela yokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Melanoma uhlobo lomdlavuza wesikhumba olusuka kuma-melanocyte, okungamaseli akhiqiza umbala. Iwuhlobo oluyingozi kakhulu lomdlavuza wesikhumba futhi ungasakazeka ngokushesha kwezinye izingxenye zomzimba uma ungelashwa. I-melanoma ingakheka futhi esweni elaziwa ngokuthi yi-ocular melanoma nangaphakathi kwekhala, umlomo, umphimbo, indawo yangasese noma i-anal, eyaziwa ngokuthi i-melanoma ye-mucosal. Izimpawu ze-melanoma zingabandakanya izinguquko ekubunjweni, umbala, noma usayizi wama-moles akhona, ukuvela kwama-moles amasha, noma ukukhula kwezilonda ezingapholi. Ukwelashwa kwe-melanoma kuncike esiteji futhi kungase kuhlanganise ukuhlinzwa, ukwelashwa ngemisebe, i-chemotherapy, noma ukwelashwa okuhlosiwe. Kubalulekile ukuqaphela izici eziyingozi ezihlobene ne-melanoma, okuhlanganisa izakhi zofuzo nokuchayeka elangeni, futhi uthathe izinyathelo zokuphepha ezinjengokugqoka i-sunscreen nezingubo zokuzivikela. Ukuzihlola njalo, kanye nokuhlolwa okujwayelekile nodokotela wesikhumba, kungasiza ekuxilongweni kusenesikhathi futhi kuthuthukise izinga lokusinda kwe-melanoma.

Ku-Melanoma, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - kumdlavuza onjenge-melanoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengeMelanoma?

Isibonelo, ingabe kunendaba ukuthi iCauliflower yemifino idliwa kakhulu uma iqhathaniswa ne-American Pokeweed? Ingabe kuyawenza umehluko uma isithelo i-Malabar Plum sikhethwa kune-Black Mulberry? Futhi uma ukukhetha okufanayo kwenziwa ngamantongomane/imbewu efana ne-Butternut phezu kwe-European Chestnut kanye nama-pulses afana no-Broad Bean phezu kwe-Pigeon Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Melanoma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onesifo esifanayo noma engozini yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Melanoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Malabar Plum iqukethe izithako ezisebenzayo i-Myricetin, i-Lycopene, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Futhi I-Black Mulberry iqukethe izithako ezisebenzayo i-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde kanye nezinye okungenzeka.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ngenxa ye-Melanoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo somsoco we-Melanoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Kwe-Melanoma?

Ukondleka komuntu siqu komdlavuza njengeMelanoma kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-melanoma, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Melanoma

Yonke imidlavuza efana ne-Melanoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Melanoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-RAS-RAF Signaling, Inositol Phosphate Signaling, Extracellular Matrix Remodelling, Focal Adhesion ziyingxenye yencazelo yesiginesha yeMelanoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Ukwelashwa okusebenzayo kwe-Melanoma kudinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa nge-Melanoma lapho uthatha ukwelashwa komdlavuza i-Dabrafenib, futhi okunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-MUC16, BRAF, APOB, MGAM kanye ne-NRAS yizakhi zofuzo ezikleliswe phezulu ze-Melanoma. I-MUC16 ibikwa ku-7.5 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-BRAF ibikwa ku-4.9%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esukela kweyi-5 kuye kwengama-90. Amaphesenti angama-62.8 emininingwane yesiguli ahlonzwa njengabesilisa. Ibhayoloji ye-Melanoma kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako zeMelanoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha iVegetable CAULIFLOWER noma i-AMERICAN POKEWEED?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde, i-Formononetin, i-Phloretin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, i-Amino Acid Metabolism kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Cauliflower iyanconywa nge-Melanoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib. Lokhu kungenxa yokuthi ukholifulawa uguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Dabrafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yase-American Pokeweed yi-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oxidative Stress nezinye. I-American Pokeweed ayinconyelwe i-Melanoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib ngoba ilungisa lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-VEGETABLE CAULIFLOWER INCONYISWA NGE-AMERICAN POKEWEED FOR Melanoma KANYE NOKWELASHWA I-Dabrafenib.

Khetha Isithelo EMNYAMA MULBERRY noma i-MALABAR PLUM?

I-Fruit Black Mulberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Quercetin, i-Myricetin, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Ukulungiswa Kwe-DNA, Ukusayina Kwe-Growth Factor kanye ne-Epithelial to Mesenchymal Transition nezinye. I-Black Mulberry inconywa nge-Melanoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib. Lokhu kungenxa yokuthi uMulberry Omnyama uguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Dabrafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Malabar Plum yi-Myricetin, i-Lycopene, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-DNA Repair kanye ne-Oxidative Stress nezinye. I-Malabar Plum ayinconyelwe i-Melanoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-FRUIT MULBERRY EMNYAMA INCONYISWA NGE-MALABAR PLUM YE-Melanoma KANYE NOKWELASHWA I-Dabrafenib.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Myricetin, i-Lycopene, i-Curcumin, i-Isoliquiritigenin, i-Cinnamaldehyde. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Ukulungiswa kwe-DNA kanye nokusayina kwe-insulin nezinye. I-Butternut inconywa nge-Melanoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Dabrafenib.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Quercetin, i-Ellagic Acid, i-Myricetin, i-Curcumin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-DNA Repair, i-WNT Beta Catenin Signaling, i-Epithelial to Mesenchymal Transition kanye ne-Oxidative Stress nezinye. I-Chestnut yase-Europe ayinconyelwe i-Melanoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Dabrafenib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-BUTTERNUT INCONYISWA NGE-CHESTNUT YASE-EUROPE NGE-melanoma KANYE NOKWELASHWA I-Dabrafenib.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abasengozini yofuzo ye-melanoma noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha I-Vegetable GIANT BUTTERBUR noma i-TURNIP?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokusayina kwe-MAPK, Ukusayina kwe-RAS-RAF, Ukusayinda kwe-MYC kanye nokusayina kwe-PI3K-AKT-MTOR nokunye. I-Butterbur Enkulu inconywa engcupheni ye-Melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-turnip yemifino yi-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Cell Cycle kanye ne-PI3K-AKT-MTOR Signaling nezinye. Itheniphu ayinconywa uma ingozi ye-melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYWA NGENXA YOKUJINJWA KWE-APOB GENETIC RISK OF CANCER.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, Growth Factor Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Okusajingijolo Okubomvu kunconywa engcupheni ye-Melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB. Lokhu kungenxa yokuthi i-Red Raspberry inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints kanye ne-Extracellular Matrix Remodeling nezinye. I-Pummelo ayinconywa uma ingozi ye-melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB ngoba inyusa izindlela zayo zokusayina.

I-RASPBERRY EBOMVU YESITHELO INCONYISWA NGAPHEZU KWE-PUMMELO YE-APOB GENETIC RISK OF CANCER.

Khetha Nut COMMON HAZELNUT noma MACADAMIA NUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, Growth Factor Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Hazelnut evamile inconywa engcupheni ye-Melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Macadamia Nut yi-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Macadamia Nut ayinconywa uma ingozi ye-Melanoma uma ingozi yofuzo ehlotshaniswa nayo i-APOB ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-MACADAMIA NUT NGENGOZI YE-APOB GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njenge-Melanoma. Iziguli ze-melanoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungekona?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Melanoma, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana nokholifulawa kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene futhi ahlukene emizila ye-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo sokwenza kube ngokwakho umsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethele noma ngingakukhetheli i-Melanoma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• Ingqungquthela 2018
• I-Curcuminoids Idala Izinhlobo Ze-oksijeni Ezisebenzayo kanye ne-Autophagy ukuze Kuthuthukiswe i-Apoptosis kumaseli omdlavuza womlomo womuntu.
• I-Morusin idala ukufa kweseli ngokuvala ukusayina kwe-STAT3 kumaseli omdlavuza wendlala yesinye.
• Ukuthatha i-mulberry 1-deoxynojirimycin kuvimbela umdlavuza we-colorectal kumagundane.
• I-Brassinin Icindezela Amathuba Okuhlaselayo Amaseli E-Carcinoma Emaphaphu Ngokuyekisa ukusebenza kwe-PI3K/Akt/mTOR Signaling Cascade.
• I-Vitamin C ibulala amangqamuzana omdlavuza wegilo ngokusebenzisa ukuvinjelwa okuncike ku-ROS kwe-MAPK/ERK kanye ne-PI3K/AKT izindlela ngezindlela ezihlukile.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.
• https://www.ncbi.nlm.nih.gov/books/NBK470409
• https://www.cancer.org/cancer/types/melanoma-skin-cancer/about/what-is-melanoma.html