Ukudla kwe-Alveolar Soft Part Sarcoma!

Isingeniso

Ukudla kwe-Alveolar Soft Part Sarcoma kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Alveolar Soft Part Sarcoma (ASPS) iwuhlobo olungavamile noluhlukile lwe-tissue sarcoma ethambile, ebonakala ngezici ezihlukile ku-pathology kanye ne-radiology. Ivame ukuphawulwa ngesakhiwo sayo se-alveolar kuhlaka lwe-pathology, lapho amaseli wesimila ahlelwa ngephethini efana nesidleke. Indlela eqondile engaphansi kwe-ASPS ixhunywe ku-chromosomal translocation, okuwuphawu lwalo mdlavuza.

Ku-radiology, ikakhulukazi nge-MRI, i-ASPS ibonakala njengesisindo esichazwe kahle. Iqhaza lokuthwebula izithombe libalulekile kukho kokubili ukuhlonza kanye nokubeka isifo, kanye nokuqapha ukuphendula ekwelashweni. Izimpawu ze-ASPS zingahluka ngokuya endaweni yesimila kodwa zingabandakanya inqwaba ezwakalayo noma ubuhlungu endaweni ethintekile.

Ukwelashwa kwe-Alveolar Soft Part Sarcoma ngokuvamile kuhilela inhlanganisela yokuhlinzwa kanye nokwelashwa kwesistimu. Uma kubhekwa ukumelana nesimila ekwelashweni okujwayelekile kwamakhemikhali, izindlela ezintsha ezifana ne-immunotherapy ziyahlolwa, ngezidakamizwa ezinjenge-Atezolizumab ezikhombisa amandla kwezinye izimo. Ukwengeza, izindlela zokwelapha ezihlosiwe kanye namanye ama-ejenti anoveli asaphenywa.

Ukubikezela kanye nesikhathi sokuphila kweziguli ezine-ASPS kuncike ezintweni ezimbalwa, okuhlanganisa isigaba sokuxilongwa kanye nokuphendula kwesimila ekwelashweni. Isigaba 4 I-Alveolar Soft Part Sarcoma, lapho umdlavuza usuqhamuke khona, isikhathi esiningi sokuphila siphansi uma siqhathaniswa nezigaba zangaphambili. Nokho, ukubikezela komuntu ngamunye kungahluka kakhulu.

Intuthuko ku-immunohistochemistry iye yasiza ekuxilongeni okunembile kwe-ASPS, yanikeza imininingwane ngebhayoloji yesimila kanye nokuqondisa ukukhetha kokwelashwa okuhlosiwe okungenzeka. Ukulandelela njalo nokuqapha kubalulekile, njengoba i-ASPS ingaphinda iphinde noma iqhubeke ngisho nangemva kokwelashwa kokuqala. Ukubhala ngekhodi kwe-ICD-10 kwe-Alveolar Soft Part Sarcoma kusiza ekurekhodeni okuhlelekile nokulandelelwa kwalo mdlavuza ongavamile ngezinjongo zocwaningo nokwelashwa.

Nge-Alveolar Soft Part Sarcoma ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza njenge-Alveolar Soft Part Sarcoma ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Alveolar Soft Part Sarcoma?

Isibonelo, ingabe kunendaba ukuthi iCauliflower yemifino idliwa kakhulu uma iqhathaniswa ne-Agave? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kuneRed Raspberry? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-Chestnut kanye nama-pulses afana nobhontshisi obanzi phezu kukabhontshisi ovamile. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Alveolar Soft Part Sarcoma futhi ingabe iyimpendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Alveolar Soft Part Sarcoma!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo iPummelo iqukethe izithako ezisebenzayo iFormononetin, Quercetin, Lupeol, Caffeine, Bergapten. Futhi okusajingijolo okubomvu kuqukethe izithako ezisebenzayo iFormononetin, Quercetin, Lupeol, Bergapten, Ellagic Acid kanye nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Alveolar Soft Part Sarcoma - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla kwe-Alveolar Soft Part Sarcoma.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Alveolar Soft Part Sarcoma?

Ukondleka komuntu siqu komdlavuza njenge-Alveolar Soft Part Sarcoma iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji ye-Alveolar Soft Part Sarcoma, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Alveolar Soft Part Sarcoma

Yonke imidlavuza efana ne-Alveolar Soft Part Sarcoma ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Alveolar Soft Part Sarcoma. Izindlela zamakhemikhali ezinto eziphilayo ezifana nokulungisa i-DNA, i-JAK-STAT Signaling, PI3K-AKT-MTOR Signaling, Mismatch Repair ziyingxenye yencazelo yesiginesha ye-Alveolar Soft Part Sarcoma. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Alveolar Soft Part Sarcoma zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ye-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa nge-Alveolar Soft Part Sarcoma lapho uthatha ukwelashwa komdlavuza i-Atezolizumab, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-SLIT2, AMER1, KEAP1, GRM3 kanye ne-FOXO1 yizakhi zofuzo ezisezingeni eliphezulu ezibikwayo ze-Alveolar Soft Part Sarcoma. I-SLIT2 ibikwa kuma-28.6 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-AMER1 ibikwa ku-14.3%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. U-55.0 % wemininingwane yesiguli uhlonzwa njengabesilisa. I-Alveolar Soft Part Sarcoma biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelelwe izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Alveolar Soft Part Sarcoma

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha i-Vegetable CAULIFLOWER noma i-AGAVE?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Lupeol, i-Bergapten, i-Curcumin, i-Phloretin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Ukholifulawa uyanconywa nge-Alveolar Soft Part Sarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab. Lokhu kungenxa yokuthi ukholifulawa uguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Atezolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Agave yemifino yi-Formononetin, i-Lupeol, i-Bergapten, i-Curcumin, i-Caffeic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-Mismatch Repair kanye ne-DNA Repair nezinye. I-Agave ayinconyelwe i-Alveolar Soft Part Sarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-VEGETABLE CAULIFLOWER INCONYISWA NGENXA YE-AGAVE YE-Alveolar Soft Part Sarcoma KANYE NOKWELASHWA I-Atezolizumab.

Khetha Isithelo RED RASPBERRY noma i-PUMMELO?

I-Fruit Red Raspberry iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Quercetin, i-Lupeol, i-Bergapten, i-Ellagic Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Red Raspberry iyanconywa nge-Alveolar Soft Part Sarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab. Lokhu kungenxa yokuthi i-Red Raspberry iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Atezolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni iPummelo yiFormononetin, Quercetin, Lupeol, Caffeine, Bergapten. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-Mismatch Repair kanye ne-DNA Repair nezinye. I-Pummelo ayinconyelwe i-Alveolar Soft Part Sarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-RASPBERRY YESITHELO EBOMVU INCONYISWA NGAPHEZU KWE-PUMMELO YE-Alveolar Soft Part Sarcoma KANYE NOKWELASHWA I-Atezolizumab.

Khetha Nut BUTTERNUT noma CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Formononetin, i-Lupeol, i-Caffeine, i-Bergapten, i-Curcumin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-JAK-STAT Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Butternut iyanconywa nge-Alveolar Soft Part Sarcoma lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab. Lokhu kungenxa yokuthi i-Butternut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Atezolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Formononetin, i-Lupeol, i-Caffeine, i-Bergapten, i-Ellagic Acid. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene zamakhemikhali ezinto eziphilayo njenge-Mismatch Repair kanye ne-DNA Repair nezinye. I-Chestnut ayinconyelwe i-Alveolar Soft Part Sarcoma uma ukwelashwa komdlavuza okuqhubekayo kuyi-Atezolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IBUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT NGE-Alveolar Soft Part Sarcoma KANYE NOKWELASHWA I-Atezolizumab.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwe abantu abasengozini yofuzo ye-Alveolar Soft Part Sarcoma noma umlando womndeni uthi "Yini Okufanele Ngidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable GIANT BUTTERBUR noma IBATATO?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Angiogenesis, i-EPHRIN Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Giant Butterbur inconywa engcupheni ye-Alveolar Soft Part Sarcoma lapho ubungozi bofuzo obuhlobene bungu-AMER1. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives kuPotato yemifino yi-Curcumin, i-Lupeol, i-Formononetin, i-Quercetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress nezinye. Izambane alituswa uma ingozi ye-Alveolar Soft Part Sarcoma uma ingozi yofuzo ehlotshaniswa nayo ingu-AMER1 ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYISWA NGAPHEZU KWEZAMBATO NGENGOZI YOFUZO YE-AMER1 YOMFUZA.

Khetha Isithelo TAMARIND noma I-MULBERRY EMNYAMA?

I-Fruit Tamarind iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Linalool. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Angiogenesis, PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Tamarind inconyelwa engcupheni ye-Alveolar Soft Part Sarcoma uma ingozi yofuzo ehlotshaniswa nayo ingu-AMER1. Lokhu kungenxa yokuthi i-Tamarind inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni sikaMulberry Omnyama yi-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Quercetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress nezinye. I-Black Mulberry ayinconywa uma ingozi ye-Alveolar Soft Part Sarcoma uma ingozi yofuzo ehlotshaniswa nayo ingu-AMER1 ngoba inyusa izindlela zayo zokusayina.

I-TAMARIND YESITHELO INCONYISWA NGAPHEZU KWE-MULBERRY OMNYAMA NGENGOZI YE-AMER1 YOFUZO LOMKHANZA.

Khetha Nut COMMON HAZELNUT noma PILI NUT?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Formononetin, i-Quercetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress, Angiogenesis, PI3K-AKT-MTOR Signaling kanye ne-P53 Signaling nezinye. I-Hazelnut Ejwayelekile inconywa engcupheni ye-Alveolar Soft Part Sarcoma lapho ubungozi bofuzo obuhlobene bungu-AMER1. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Pili Nut yi-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oxidative Stress kanye ne-Cell Cycle Checkpoints nezinye. I-Pili Nut ayituswa uma ubungozi be-Alveolar Soft Part Sarcoma uma ingozi yofuzo ehlotshaniswa nayo ingu-AMER1 ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-PILI NUT FOR AMER1 GENETIC RISK OF CANCER.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Alveolar Soft Part Sarcoma. Iziguli ze-Alveolar Soft Part Sarcoma kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungekona?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Alveolar Soft Part Sarcoma, ngayinye enezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana nokholifulawa kuqukethe ama-bioactive ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene futhi ahlukene emizila ye-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, “Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Alveolar Soft Part Sarcoma?”. Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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• I-Pan Origimed 2020
• I-Genomic Profiling of Childhood Tumor Amamodeli E-Xenograft Asuselwa Esigulini Ukuze Unike Amandla Idizayini Yesivivinyo Somtholampilo Esiphusile.
• I-Formononetin-induced oxidative stress iqeda ukwenziwa kusebenze kwe-STAT3/5 signing axis futhi icindezela ukukhula kwesimila kumodeli ye-myeloma preclinical eminingi.
• Ukulawulwa okungekuhle kwe-transducer yesiginali kanye ne-activator ye-transcription-3 signaling cascade nge-lupeol ivimbela ukukhula futhi yenze i-apoptosis kumaseli e-hepatocellular carcinoma.
• I-Brassinin ivimbela indlela yokusayina ye-STAT3 ngokushintshwa kwe-PIAS-3 ne-SOCS-3 expression futhi iqwashise i-xenograft yomdlavuza wamaphaphu womuntu kumagundane anqunu ku-paclitaxel.
• Imiphumela yokuvimbela ye-butyric acid, i-nicotinamide, i-calcium glucarate iyodwa noma ihlangene ngesikhathi se-7, i-12-dimethylbenz (a) i-anthracene eyenge i-tumorigenesis yesikhumba segundane ngokumodulation kwe-K-Ras-PI3K-AKTpathway kanye nama-RNA amancane ahlobene.