Ukudla komdlavuza weLaryngeal!

Isingeniso

Ukudla komdlavuza weLaryngeal kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ngomdlavuza weLaryngeal ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yomdlavuza uwukuthi - kumdlavuza onjengomdlavuza weLaryngeal ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjengeLaryngeal Cancer?

Isibonelo, ingabe kunendaba ukuthi i-Yellow Zucchini yemifino idliwa kakhulu uma iqhathaniswa neklabishi Lexhaphozi? Ingabe kuyawenza umehluko uma isithelo i-Pitanga sithandwa kune-Soursop? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Butternut phezu kwe-European Chestnut kanye nama-pulses afana ne-Gram Bean phezu kwe-Lima Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe umdlavuza weLaryngeal futhi ingabe impendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba yomdlavuza weLaryngeal!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Pitanga iqukethe izithako ezisebenzayo i-Quercetin, i-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol. Futhi i-Soursop iqukethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lupeol, i-Emodin, i-Formononetin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Laryngeal Cancer - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla komdlavuza weLaryngeal.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Adingekayo Ekwenzeni Ukudla Okunempilo Komdlavuza We-Laryngeal?

Ukondleka komuntu siqu komdlavuza njengeLaryngeal Cancer kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Laryngeal Cancer biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njengeLaryngeal Cancer

Wonke ama-cancer afana neLaryngeal Cancer angabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina zeLaryngeal Cancer. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-RAS-RAF Signaling, NFKB Signaling, PI3K-AKT-MTOR Signaling, Cell Cycle Checkpoints ziyingxenye yencazelo yesiginesha yeLaryngeal Cancer. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Laryngeal Cancer zidinga ukuqaphela izindlela ezihambisana namakhemikhali we-biochemical esigulini ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezisizayo kunconyelwa umdlavuza weLaryngeal lapho uthatha ukwelashwa komdlavuza i-Docetaxel, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TP53, NOTCH1, CDKN2A, KMT2D kanye ne-NFE2L2 yizakhi zofuzo ezikleliswe phezulu zeLaryngeal Cancer. I-TP53 ibikwa kuma-40.7 % eziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-NOTCH1 ibikwa ku-18.5%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esuka ku-52 kuya ku-67. Ama-84.7 % emininingwane yesiguli ahlonzwa njengabesilisa. I-Laryngeal Cancer biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela ze-biochemical ezisayinwe kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithasiselo Zomdlavuza WeLaryngeal

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha Imifino EYELLOW ZUCCHINI noma IKHABHISHI LAMASWAMP?

I-Vegetable Yellow Zucchini iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Hypoxia, i-NFKB Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Yellow Zucchini inconyelwa umdlavuza weLaryngeal lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel. Lokhu kungenxa yokuthi i-Yellow Zucchini ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Docetaxel.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Iklabishi Lexhaphozi yiCurcumin, iLycopene, iLupeol, iFormononetin, iDaidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Heat Stress Response nezinye. Iklabishi Lexhaphozi alituswa ku-Laryngeal Cancer uma ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel ngoba liguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-ZUCCHINI EYELOWU YESIBILI INCONYISWA NGAPHEZU KWEKHABHISHI LAMADAKAZI EMHLABENI NOKULAPHA I-Docetaxel.

Khetha Isithelo SOURSOP noma i-PITANGA?

I-Fruit Soursop iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Emodin, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana nokusayina kwe-MAPK, Ukusayinda kwe-MYC, Ukusayinda kwe-NFKB kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Soursop inconywa ku-Laryngeal Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel. Lokhu kungenxa yokuthi i-Soursop ilungisa lezo zindlela ze-biochemical ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Docetaxel.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pitanga yi-Quercetin, i-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezehlukene ze-biochemical ezifana ne-Heat Stress Response, TGFB Signaling kanye ne-NFKB Signaling nezinye. I-Pitanga ayinconyelwe umdlavuza weLaryngeal lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO SOURSOP INCONYISWA NGAPHEZU KWE-PITANGA NGOMDLALO WE-Laryngeal KANYE NOKWELAPHA I-Docetaxel.

Khetha Nut BUTTERNUT noma EUROPEAN CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana nokusayina kwe-MAPK, Ukusayina kwe-TGFB, Ukusayinda kwe-NFKB kanye nokusayina kwe-PI3K-AKT-MTOR nokunye. I-Butternut inconywa ku-Laryngeal Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel. Lokhu kungenxa yokuthi i-Butternut ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezibikwe ngokwesayensi ukuze ziqwashise umthelela we-Docetaxel.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yaseYurophu yi-Quercetin, i-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Heat Stress Response nezinye. I-Chestnut yase-Europe ayinconyelwe umdlavuza weLaryngeal lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Docetaxel ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-CHESTNUT YASE-EUROPE FOR Laryngeal Cancer KANYE NOKWELASHWA I-Docetaxel.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa ngabantu abanengozi yofuzo yeLaryngeal Cancer noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha Imifino CALABASH noma i-ARROWHEAD?

I-Vegetable Calabash iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Oxidative Stress, Stem Cell Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Calabash inconyelwe engcupheni Yomdlavuza WeLaryngeal lapho ubungozi bofuzo obuhambisanayo kuyi-CDKN2A. Lokhu kungenxa yokuthi i-Calabash inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Arrowhead yemifino yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints kanye ne-Oxidative Stress nezinye. I-Arrowhead ayinconywa uma ingozi yeLaryngeal Cancer uma ingozi yofuzo ehlotshaniswa nayo iyi-CDKN2A ngoba inyusa izindlela zayo zokusayina.

I-Vegetable CALABASH INCONYISWA NGAPHEZU KWE-ARROWHEAD NGE-CDKN2A GENETIC RISK OF CANCER.

Khetha Isithelo NANCE noma i-MUSCADINE GRAPE?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, Oxidative Stress, Stem Cell Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Nance inconywa engcupheni yomdlavuza weLaryngeal lapho ingozi yofuzo ehlobene iyi-CDKN2A. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni se-Muscadine Grape yi-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints kanye ne-Stem Cell Signaling nezinye. I-Muscadine Grape ayinconywa uma ingozi yomdlavuza weLaryngeal uma ingozi yofuzo ehambisana nayo i-CDKN2A ngoba inyusa izindlela zayo zokusayina.

ISITHELO NANCE KUNCONYWA NGAPHEZU KWAMAGILIPI E-MUSCADINE WE-CDKN2A GENETIC RISK OF CANCER.

Khetha Nut COMMON HAZELNUT noma FLXSEED?

I-Hazelnut evamile iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Daidzein, i-Quercetin, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, PI3K-AKT-MTOR Signaling, Stem Cell Signaling kanye ne-Oxidative Stress nezinye. I-Hazelnut evamile inconywa engcupheni Yomdlavuza WeLaryngeal lapho ubungozi bofuzo obuhlobene buyi-CDKN2A. Lokhu kungenxa yokuthi i-Common Hazelnut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Flaxseed yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR Signaling kanye ne-Oxidative Stress nezinye. I-Flaxseed ayituswa uma ingozi yeLaryngeal Cancer uma ingozi yofuzo ehlotshaniswa nayo iyi-CDKN2A ngoba inyusa izindlela zayo zokusayina.

I-HAZELNUT EJWAYELEKILE INCONYISWA NGAPHEZU KWE-FLAXSEED YE-CDKN2A GENETIC RISK OF CANCER.

Ekuphetheni

Ukudla kanye Nezithako ezikhethiwe yizinqumo ezibalulekile zomdlavuza njengeLaryngeal Cancer. Iziguli zomdlavuza weLaryngeal kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana neLaryngeal Cancer, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Yellow Zucchini kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli Umdlavuza weLaryngeal?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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