Ukudla kwe-High-grade Neuroepithelial Tumor!

Isingeniso

Ukudla kwe-High-grade Neuroepithelial Tumor kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Nge-High-grade Neuroepithelial Tumor, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu adlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza njenge-High-grade Neuroepithelial Tumor ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza njenge-High-grade Neuroepithelial Tumor?

Isibonelo, ingabe kunendaba ukuthi imifino ye-Sweet Potato idliwa kakhulu uma iqhathaniswa ne-American Pokeweed? Ingabe kuyawenza umehluko uma isithelo iPummelo sithandwa kunoMango? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Pistachio phezu kwe-Hickory Nut kanye nama-pulses afana nobhontshisi oluhlaza phezu kwe-Adzuki Bean. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe I-High-grade Neuroepithelial Tumor futhi ingabe iyimpendulo efanayo kuwo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kunezindaba ze-High-grade Neuroepithelial Tumor!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo i-Pummelo iqukethe izithako ezisebenzayo i-Curcumin, i-Quercetin, i-Genistein, i-Isoliquiritigenin, i-Lupeol. Futhi umango uqukethe izithako ezisebenzayo i-Curcumin, i-Vitamin C, i-Quercetin, i-Genistein, i-Isoliquiritigenin futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-High-grade Neuroepithelial Tumor - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla okunomsoco we-High-grade Neuroepithelial Tumor.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okuthandwa Nguwe Kwesimila Se-Neuroepithelial Yezinga Eliphezulu?

Ukondleka komuntu siqu komdlavuza njenge-High-grade Neuroepithelial Tumor iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-High-grade Neuroepithelial Tumor biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhlobene lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-High-grade Neuroepithelial Tumor

Wonke ama-cancer afana ne-High-grade Neuroepithelial Tumor angabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-High-grade Neuroepithelial Tumor. Izindlela ze-Biochemical ezifana ne-Oncogenic Cancer Epigenetics, i-Suppressive Histone Methylation, i-Notch Signaling, i-Amino Acid Metabolism iyingxenye yencazelo yesiginesha ye-High-grade Neuroepithelial Tumor. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo kwi-High-grade Neuroepithelial Tumor zidinga ukuqaphela izindlela ezihambisanayo zesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kuyanconywa nge-High-grade Neuroepithelial Tumor lapho uthatha ukwelashwa komdlavuza i-Pembrolizumab, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-ASXL1, DNMT3A, MYCN kanye ne-NOTCH1 yizinhlobo zofuzo ezikleliswe phezulu ezisezingeni eliphezulu ze-Neuroepithelial Tumor. I-ASXL1 ibikwa ku-25.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-DNMT3A ibikwa ku-25.0 %. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka yobudala esukela kwengu-1 kuye kwengama-74. Ama-50.0 % emininingwane yesiguli ahlonzwa njengabesilisa. I-High-grade Neuroepithelial Tumor biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelwe ukusayina izindlela ze-biochemical kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-High-grade Neuroepithelial Tumor

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha I-Vegetable SWEET PATATO noma I-AMERICAN POKEWEED

I-Vegetable Sweet Potato iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Beta-carotene, i-Vitamin C, i-Quercetin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Ubhatata uyanconywa nge-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab. Lokhu kungenxa yokuthi Izambane Elimnandi liguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Pembrolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yase-American Pokeweed yi-Curcumin, i-Beta-carotene, i-Quercetin, i-Genistein, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zishintsha izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling nezinye. I-American Pokeweed ayinconyelwe I-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IZAZI ELIMNANDI ELIMUSHINI KUNCONYWA NGE-POKEWEED YASE-AMERICAN NGESImila Se-Neuroepithelial Esezingeni eliphezulu KANYE NOKWELASHWA I-Pembrolizumab.

Khetha i-Fruit MANGO noma i-PUMMELO

Imango Yezithelo iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Vitamin C, i-Quercetin, i-Genistein, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. Umango utuswa nge-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab. Lokhu kungenxa yokuthi umango uguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Pembrolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Curcumin, i-Quercetin, i-Genistein, i-Isoliquiritigenin, i-Lupeol. Lezi zithako ezisebenzayo zishintsha izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling nezinye. I-Pummelo ayinconyelwe i-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

UMANGO WESITHELO UNCONYISWA NGAPHEZU KWE-PUMMELO NGESIQINISEKISO SE-Neuroepithelial Tumor KANYE NOKWELASHWA I-Pembrolizumab.

Khetha Nut PISTACHIO noma HICKORY NUT

I-Pistachio iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Quercetin, i-Genistein, i-Isoliquiritigenin, i-Lupeol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Pistachio inconywa nge-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab. Lokhu kungenxa yokuthi i-Pistachio ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Pembrolizumab.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Hickory Nut yi-Curcumin, i-Genistein, i-Isoliquiritigenin, i-Lupeol, i-Beta-sitosterol. Lezi zithako ezisebenzayo zishintsha izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling nezinye. I-Hickory Nut ayinconyelwe I-High-grade Neuroepithelial Tumor lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Pembrolizumab ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-PISTACHIO INCONYISWA NGAPHEZU KWE-HICKORY NUTSHOLO WE-High-grade Neuroepithelial Tumor KANYE NOKWELASHWA I-Pembrolizumab.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo ye-High-grade Neuroepithelial Tumor noma umlando womndeni uthi "Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?" nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha iVegetable BITTER GOURD noma IBATA

I-Vegetable Bitter Gourd iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-Cell Cycle Checkpoints, Cell Cycle, Apoptosis kanye ne-PI3K-AKT-MTOR Signaling nezinye. IBitter Gourd inconyelwa engcupheni Ye-High-grade Neuroepithelial Tumor lapho ubungozi bofuzo obuhlobene buyi-ASXL1. Lokhu kungenxa yokuthi i-Bitter Gourd inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Potato yemifino yi-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-WNT Beta Catenin Signaling, Stem Cell Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Izambane alituswa uma ingozi ye-High-grade Neuroepithelial Tumor lapho ingozi yofuzo ehlobene i-ASXL1 ngoba inyusa izindlela zayo zokusayina.

IGANDA ELIBUYA ELINCINJWAYO LIYANCONYISWA PHEZU KWEZAMBATO NGENGOZI YOMFUZA I-ASXL1 yofuzo.

Khetha isithelo i-JAVA PLUM noma i-ALASKA BLUEBERRY

I-Fruit Java Plum iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-Apoptosis, i-MYC Signaling, i-Focal Adhesion kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Java Plum inconyelwe engcupheni Ye-High-grade Neuroepithelial Tumor lapho ubungozi bofuzo obuhlobene buyi-ASXL1. Lokhu kungenxa yokuthi i-Java Plum inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Alaska Blueberry yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics, i-WNT Beta Catenin Signaling kanye ne-Stem Cell Signaling nezinye. I-Alaska Blueberry ayinconyiwe uma ingozi ye-High-grade Neuroepithelial Tumor lapho ingozi yofuzo ehlotshaniswa nayo i-ASXL1 ngoba inyusa izindlela zayo zokusayina.

ISITHELO I-JAVA PLUM INCONYISWA NGAPHEZU KWE-ALASKA BLUEBERRY NGE-ASXL1 GENETIC RISK OF CANCER.

Khetha Imbewu Yamantongomane IBHUTTERNUT noma IZIMBEWO ZAMATHANGA

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njengezindawo zokuhlola i-Cell Cycle, i-Stem Cell Signaling, i-Focal Adhesion kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Butternut inconyelwa engcupheni Ye-High-grade Neuroepithelial Tumor lapho ubungozi bofuzo obuhlobene buyi-ASXL1. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives eMbewu Yethanga yi-Beta-sitosterol, i-Stigmasterol, i-Linolenic Acid, i-Oleic Acid, i-Salicylic Acid. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-MYC Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. Imbewu yethanga ayinconywa uma ingozi ye-High-grade Neuroepithelial Tumor lapho ingozi yofuzo ehlobene i-ASXL1 ngoba yandisa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGAPHEZU KWEZINHLOBO ZAMATHANGA NGENGOZI YE-ASXL1 YOFUZO YOMDLALO.

Ekuphetheni

Ukudla Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-High-grade Neuroepithelial Tumor. Iziguli ezisezingeni eliphezulu ze-Neuroepithelial Tumor kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: "Yikuphi ukudla nezithako zokudla okunempilo engikunconyelwe futhi okungenjalo?" Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-High-grade Neuroepithelial Tumor, ngayinye ene-tumor genetics ehlukahlukene ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Sweet Potato kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela zamakhemikhali ezinto eziphilayo. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda kwezinhlobo ezahlukene zokwelapha ngamakhemikhali. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli I-High-grade Neuroepithelial Tumor?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

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