Ukudla Komdlavuza Wesinye Amaseli Amancane!

Isingeniso

Ukudla Komdlavuza Wesinye Amangqamuzana Amancane kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene ngokuphathelene nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza kanye nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

Ngomdlavuza Wesinye Amaseli Amancane Ingabe kunendaba ukuthi imifino, izithelo, amantongomane, imbewu umuntu udlani?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwa iziguli ezinomdlavuza kanye nabantu abasengozini yokuthola umdlavuza - komdlavuza ofana Nomdlavuza Wesinye Esincane Ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele lokho kumdlavuza onjengoCancer Wesinye Iseli Encane?

Isibonelo, ingabe kunendaba ukuthi imifino kaCelery Stalks idliwa kakhulu uma iqhathaniswa neHorned Melon? Ingabe kuyawenza umehluko uma izithelo zeMuscadine Grape zithandwa kuneSoursop? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Black Walnut phezu kwe-Flaxseed kanye nama-pulses afana no-Broad Bean phezu kwe-Catjang Pea. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe Umdlavuza Wesinye Amaseli Amancane futhi ingabe impendulo efanayo yawo wonke umuntu onesifo esifanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba Yomdlavuza Wesinye!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Muscadine Grape iqukethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Psoralen. Futhi i-Soursop iqukethe izithako ezisebenzayo i-Apigenin, i-Emodin, i-Curcumin, i-Lupeol, i-Psoralen futhi mhlawumbe nezinye.

Iphutha elivamile elenziwa lapho kunqunywa futhi kukhethwa ukudla okuzodliwa ku-Small Cell Bladder Cancer - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngenxa yokuthi izithako ezihlukahlukene ezisebenzayo eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla okunomsoco ku-Small Cell Bladder Cancer.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okufana Nakho Komdlavuza Wesinye Amaseli Amancane?

Ukondleka komuntu siqu komdlavuza njengomdlavuza wesinye i-Small Cell kuqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe kubhayoloji yomdlavuza wamaseli amancane, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengcupheni okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Small Cell Bladder Cancer

Yonke imidlavuza efana ne-Small Cell Bladder Cancer ingabonakala ngesethi ehlukile yezindlela ze-biochemical - izindlela zokusayina ze-Small Cell Bladder Cancer. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-Apoptosis, Izindawo Zokuhlola I-Cell Cycle, Ukusayinda kwe-MAPK, Ukusayinda i-Cytokine ziyingxenye yencazelo yesiginesha ye-Small Cell Bladder Cancer. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo kumdlavuza wamangqamuzana amancane wesinye kudingeka ziqaphele izindlela ezihambisana namakhemikhali amakhemikhali esiguli ngasinye kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezisizayo kuyanconywa ku-Small Cell Bladder Cancer lapho uthatha ukwelashwa komdlavuza i-Methotrexate, futhi okunye ukudla nezithasiselo akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-TERT kanye ne-TP53 yizakhi zofuzo ezibikwayo ezikleliswe phezulu ze-Small Cell Bladder Cancer. I-TERT ibikwa ku-100.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-TP53 ibikwa ku-100.0%. Idatha ehlanganisiwe yesiguli ihlanganisa iminyaka yobudala esuka ku-54 kuya ku-58. Amaphesenti angu-62.5 emininingwane yesiguli ahlonzwa njengabesilisa. Ibhayoloji ye-Small Cell Bladder Cancer biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimele izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni nazo zaziwa lokho kufanele futhi kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako Zomdlavuza Wesinye Amaseli Amancane

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha IZIHLABANI ZAMA-CELERY Emifino noma IKHABE LE-HORNED?

I-Vegetable Celery Stalks iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Phloretin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Celery Stalks inconywa ku-Small Cell Bladder Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate. Lokhu kungenxa yokuthi I-Celery Stalks iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Methotrexate.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino ye-Horned Melon yi-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Psoralen. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Horned Melon ayinconyelwe kumdlavuza wesinye iseli elincane uma ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IZIHLABANI ZAMAGAMA ESINGAZIQINISEKISI IYANCONYISWA NGAPHEZU KWEKHABE ELINEZINKONDLO NGOKUTHOLA Umdlavuza Wengqamuzana Encane KANYE NOKWELAPHA I-Methotrexate.

Khetha Isithelo SOURSOP noma i-MUSCADINE GRAPE?

I-Fruit Soursop iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Emodin, i-Curcumin, i-Lupeol, i-Psoralen. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Soursop inconywa ku-Small Cell Bladder Cancer lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate. Lokhu kungenxa yokuthi i-Soursop iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umphumela we-Methotrexate.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni se-Muscadine Grape yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Psoralen. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Muscadine Grape ayinconyelwe Umdlavuza Wesinye Iseli Encane uma ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate ngoba iguqula lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

ISITHELO SOURSOP INCONYISWA NGAPHEZU KWAMAGILIPI E-MUSCADINE WOmdlavuza Wengqamuzana Encane KANYE NOKWELAPHA I-Methotrexate.

Khetha Nut BLACK WALNUT noma FLEXSEED?

I-Walnut Emnyama iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Psoralen, i-Phloretin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Black Walnut inconywa kuCancer Yesinye Seseli Encane lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate. Lokhu kungenxa yokuthi I-Walnut Emnyama ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Methotrexate.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Flaxseed yi-Apigenin, i-Curcumin, i-Lupeol, i-Psoralen, i-Phloretin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical njenge-MYC Signaling nezinye. I-Flaxseed ayinconyelwe I-Small Cell Bladder Cancer uma ukwelashwa komdlavuza okuqhubekayo kuyi-Methotrexate ngoba ilungisa lezo zindlela ze-biochemical ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

I-WALNUT EMNYAMA INCONYISWA NGAPHEZU KWE-FLAXSEED NGOmdlavuza Wengqamuzana Encane KANYE NOKWELAPHA I-Methotrexate.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abanengozi yofuzo Yomdlavuza Wesinye Iseli Encane noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha i-Vegetable CAULIFLOWER noma IKHABHAGE ELIMNYAMA?

I-Cauliflower yemifino iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. Ukholifulawa utuswa ukuba sengozini Yomdlavuza Wesinye Esincane uma ingozi yofuzo ehlotshaniswa nayo iyi-TERT. Lokhu kungenxa yokuthi ukholifulawa unyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zayo zokusayina.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino Iklabishi Elimnyama yi-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical njenge-MAPK Signaling kanye ne-Oncogenic Cancer Epigenetics nezinye. I-Black Cabbage ayinconywa uma ingozi ye-Small Cell Bladder Cancer uma ingozi yofuzo ehambisana nayo iyi-TERT ngoba yandisa izindlela zayo zokusayina.

I-CAULIFLOWER YEMIJINO INCONYISWA PHEZU KWEKHABHISHI ELIMNYAMA NGENGOZI YE-TERT GENETIC YOMKHANZA.

Khetha isithelo NANCE noma i-PUMMELO?

I-Fruit Nance iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Nance inconywa ukuba ibe sengcupheni Yomdlavuza Wesinye Seseli Encane lapho ubungozi bofuzo obuhlobene buyi-TERT. Lokhu kungenxa yokuthi i-Nance inyusa lezo zindlela ze-biochemical eziphikisana nabashayeli bamasignesha bayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin. Lezi zithako ezisebenzayo zikhohlisa izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR Signaling kanye ne-Cell Cycle Checkpoints nezinye. I-Pummelo ayituswa uma ingozi Yomdlavuza Wesinye Iseli Encane uma ingozi yofuzo ehlotshaniswa nayo iyi-TERT ngoba yandisa izindlela zayo zokusayina.

I-FRUIT NANCE INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YE-TERT GENETIC YOMKHANZA.

Khetha Nut BUTTERNUT noma CHESTNUT?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Apigenin, i-Curcumin, i-Lupeol, i-Formononetin, i-Daidzein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-Stem Cell Signaling, i-P53 Signaling kanye ne-MAPK Signaling nezinye. I-Butternut inconywa ngengozi Yomdlavuza Wesinye Seseli Encane uma ingozi yofuzo ehambisana nayo iyi-TERT. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Chestnut yi-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Formononetin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Stem Cell Signaling, i-Oncogenic Cancer Epigenetics kanye ne-Cell Cycle Checkpoints nezinye. I-Chestnut ayinconywa uma ubungozi be-Small Cell Bladder Cancer uma ubungozi bofuzo obuhlobene buyi-TERT ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA PHEZU KWE-CHESTNUT NGENGOZI YE-TERT GENETIC YOMKHANZA.

Ekuphetheni

Ukudla kanye Nezithasiselo ezikhethiwe yizinqumo ezibalulekile zomdlavuza ofana nomdlavuza wamangqamuzana amancane. Iziguli ezinomdlavuza wamangqamuzana amancane kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo enginconyelwe zona futhi iziphi ezinganconyelwe?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza njenge-Small Cell Bladder Cancer, ngayinye inofuzo oluhlukile lwesimila esinokwehluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana ne-Celery Stalks kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukene wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo othi, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli Umdlavuza Weseli Encane?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• I-genomics yomtholampilo edidiyelwe yomdlavuza we-metastatic.
• I-Paederia foetida idala umsebenzi wokulwa nomdlavuza ngokushintsha ama-enzyme okuguqula i-chromatin futhi iguqule ukubonakaliswa kwezakhi zofuzo ze-cytokine ezinokuvuvukala kumaseli omdlavuza wendlala yesinye.
• Ukufakwa kwekholoni kanye nokufa kweseli lomdlavuza womlomo wesibeletho ngokuphuma kwe-cinnamic acid kulamula ngokuvinjelwa kwe-Histone Deacetylases (HDAC).
• I-α-pinene ilawula i-miR-221 futhi yenza i-G₂Ukuboshwa komjikelezo wamaseli wesigaba se-M kumaseli we-hepatocellular carcinoma.
• Umphumela we-Daidzein kumdlavuza we-prostate refractory we-hormone in vitro kanye ne-vivo uma kuqhathaniswa ne-genistein ne-soy extract: amandla e-radiotherapy.
• I-Brassinin ivimbela indlela yokusayina ye-STAT3 ngokushintshwa kwe-PIAS-3 ne-SOCS-3 expression futhi iqwashise i-xenograft yomdlavuza wamaphaphu womuntu kumagundane anqunu ku-paclitaxel.
• Ukukhuthazwa ukukhula kwamaseli e-adenocarcinoma yamaphaphu kanye namaseli amancane e-epithelial yomoya nge-beta-carotene ngokwenza kusebenze i-cAMP, i-PKA, i-CREB ne-ERK1/2.