Ukudla kwe-Waldenstrom Macroglobulinemia!

Isingeniso

Ukudla kwe-Waldenstrom Macroglobulinemia kufanele kube okuqondene nomuntu ngamunye futhi kufanele kuzivumelanise nezimo lapho ukwelashwa komdlavuza noma ukuguquka kofuzo lwesimila. Ukwenza kube ngokwakho nokuzivumelanisa nezimo kufanele kucabangele zonke izithako ezisebenzayo noma ama-bioactives aqukethwe ekudleni okuhlukene maqondana nebhayoloji yezicubu zomdlavuza, izakhi zofuzo, ukwelashwa, izimo zendlela yokuphila kanye nezintandokazi zokudla. Ngakho-ke nakuba ukudla okunomsoco kungenye yezinqumo ezibaluleke kakhulu okufanele zenziwe esigulini somdlavuza nomuntu osengcupheni yomdlavuza - ukukhetha ukudla ozokudla akuwona umsebenzi olula.

I-Waldenstrom macroglobulinemia iyisifo segazi esingandile, esingamahlalakhona esithinta amangqamuzana egazi amhlophe (ama-lymphocyte). Iwuhlobo lwe-non-Hodgkin lymphoma. Ibizwa nangokuthi i-lymphoplasmacytic lymphoma. Umdlavuza wegazi ongavamile, okhula kancane, obonakala ngokuba khona kwamazinga aphezulu e-macroglobulin (i-immunoglobin M [IgM]. Iphrotheni engu-M ishubisa igazi, ithinte ukugeleza kwegazi emithanjeni yegazi emincane, isimo esiyivelakancane esiyingqayizivele. ku-Waldenstrom macroglobulinemia ebizwa ngokuthi i-hyper viscosity syndrome.I-viscous serum ngezinye izikhathi ingabangela izinyembezi emithanjeni yegazi emincane, ibangele ikhala, izinsini, noma i-retinas emehlweni kuphume igazi.Ngaphezu kwalokho, umnkantsha ulokhu ugcwala amangqamuzana angavamile. kanye nokucinanisa amangqamuzana egazi avamile okuholela ekwehleni kwamangqamuzana egazi abomvu, ama-neutrophils namaplatelet futhi kubangele izimo ze-cytopenic ezifana ne-anemia, i-neutropenia, ne-thrombocytopenia. ye-macroglobulinemia ye-Waldenstrom ihlanganisa ukukhathala, imfiva, ukungakuthandi ukudla, ukujuluka ebusuku, ukuba buthakathaka, ukopha, ukungaboni kahle, ukukhuliswa kwesibindi noma ubende kanye nama-lymph nodes avuvukele. Esinye sezimbangela eziyinhloko ze-Waldenstrom macroglobulinemia kuma-90% eziguli ezixilongwayo ukuguqulwa kofuzo lwe-MYD88. Izinga lokusinda leminyaka emi-5 leziguli ezitholwe zinalesi simo zingama-78% (i-American Cancer Society, 2022). Izinketho zokwelapha ze-Waldenstrom macroglobulinemia zihlanganisa i-plasmapheresis (i-plasma exchange), i-chemotherapy, i-immunotherapy, ukwelapha okuhlosiwe, ukwelapha ngemisebe kanye nokufakelwa kwe-stem cell noma umnkantsha. Ukwengeza, ukudla okulungile (ukudla nezithako zemvelo) okuhambisana nesigaba somdlavuza kanye nesimo sokwelashwa kungathuthukisa inhlalakahle yeziguli.

Ku-Waldenstrom Macroglobulinemia, ingabe kunendaba ukuthi iyiphi imifino, izithelo, amantongomane, imbewu umuntu ayidlayo?

Umbuzo ovame kakhulu wokudla okunomsoco obuzwe iziguli ezinomdlavuza kanye nabantu abangaba sengcupheni yomdlavuza ukuthi - komdlavuza njenge-Waldenstrom Macroglobulinemia ingabe kunendaba ukuthi yikuphi ukudla engikudlayo nokuthi yikuphi engingakudli? Noma uma ngilandela ukudla okusekelwe ezitshalweni ingabe kwanele umdlavuza onjenge-Waldenstrom Macroglobulinemia?

Isibonelo, ingabe kunendaba ukuthi imifino ye-Chicory Leaves idliwa kakhulu uma iqhathaniswa ne-Winter Squash? Ingabe kuyawenza umehluko uma izithelo zeGrapefruit zithandwa kunePear? Futhi uma ukukhetha okufanayo kwenziwa kumantongomane/imbewu efana ne-Walnut phezu kweWalnut yaseJapane kanye namapulses afana ne-Cowpea phezu kwe-White Lupine. Futhi uma lokho engikudlayo kubalulekile - khona-ke umuntu ukuhlonza kanjani ukudla okunconyelwe i-Waldenstrom Macroglobulinemia futhi ingabe iyimpendulo efanayo yawo wonke umuntu onokuxilonga okufanayo noma ingozi yofuzo?

Yebo! Ukudla okudlayo kuyindaba ye-Waldenstrom Macroglobulinemia!

Izincomo zokudla zingase zingafani kuwo wonke umuntu futhi zingahluka ngisho nasekuxilongweni okufanayo nobungozi bofuzo.

Konke ukudla (imifino, izithelo, amantongomane, imbewu, ama-pulses, amafutha njll.) kanye nezithako zokudla okunomsoco kwakhiwa ngaphezu kwesithako samangqamuzana esisebenzayo esingaphezu kwesisodwa noma ama-bio-active ngezilinganiso namanani ahlukene. Isithako ngasinye esisebenzayo sinomshini wokusebenza oyingqayizivele - okungase kube ukuqalisa noma ukuvimbela izindlela ezahlukene ze-biochemical. Kalula nje ukudla nezithako ezinconyiwe yilezo ezingabangeli ukwanda kwamangqamuzana abangela umdlavuza kodwa eziwehlisayo. Uma kungenjalo lokho kudla akufanele kunconywe. Ukudla kuqukethe izithako ezisebenzayo eziningi - ngakho-ke lapho uhlola ukudla nezithako zokudla udinga ukucabangela umthelela wazo zonke izithako ezisebenzayo ngokunqwabelanayo kunokuba ucabange ngazodwana.

Isibonelo I-Grapefruit iqukethe izithako ezisebenzayo i-Chlorogenic Acid, i-Ferulic Acid, i-Curcumin, i-Isoliquiritigenin, i-Delphinidin. Futhi Pear iqukethe izithako ezisebenzayo Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Genistein futhi ngokunokwenzeka nabanye.

Iphutha elivamile elenziwe lapho kunqunywa futhi kukhethwa ukudla okuzodliwa kwe-Waldenstrom Macroglobulinemia - ukuhlola izithako ezisebenzayo ezikhethiwe kuphela eziqukethwe ekudleni futhi ungazinaki ezinye. Ngoba izithako ezisebenzayo ezahlukahlukene eziqukethwe ekudleni zingase zibe nemiphumela ephikisanayo kubashayeli bomdlavuza - awukwazi ukukhetha izithako ezisebenzayo ekudleni nasezithasiselweni ukuze wenze isinqumo sokudla okunempilo kwe-Waldenstrom Macroglobulinemia.

YEBO – IZIKHETHO ZOKUDLA ZIBALULEKILE EMHLABENI. IZINQUMO ZOKUDLA KUFANELE ZICABANGE ZONKE IZITHAKO EZISEBENZAYO ZOKUDLA.

Amakhono Ayadingeka Ekwenzeni Ukudla Okungokwakho Kwe-Waldenstrom Macroglobulinemia?

Ukondleka komuntu siqu komdlavuza njenge-Waldenstrom Macroglobulinemia iqukethe ukudla okunconyiwe / izithasiselo; ukudla okunganconyiwe / izithasiselo ezinezibonelo zokupheka ezibeka phambili ukusetshenziswa kokudla okunconyiwe. Isibonelo sokudla komuntu siqu singabonakala kulokhu isixhumanisi.

Ukunquma ukuthi yikuphi ukudla okunconyiwe noma okunganconyiwe kuyinkimbinkimbi kakhulu, kudinga ubuchwepheshe ku-Waldenstrom Macroglobulinemia biology, isayensi yokudla, izakhi zofuzo, i-biochemistry kanye nokuqonda kahle ukuthi ukwelapha umdlavuza kusebenza kanjani kanye nokuba sengozini okuhambisana nakho lapho ukwelashwa kungayeka ukusebenza kahle.

UBUCHWEPHESHE OBUNINGI OBUDINGEKA UBUCHWEPHESHE BOMUNTU WOKUDLA KWAMUNTU KOMDLALO YI: IBHYOLOGY YOMDLAVUZA, ISAYENSI YOKUDLA, UKWELASHWA KOMDLAVUZA KANYE NOFUZO.

Izimpawu zomdlavuza njenge-Waldenstrom Macroglobulinemia

Yonke imidlavuza efana ne-Waldenstrom Macroglobulinemia ingabonakala ngesethi eyingqayizivele yezindlela ze-biochemical - izindlela zokusayina ze-Waldenstrom Macroglobulinemia. Izindlela zamakhemikhali ezinto eziphilayo ezifana ne-NFKB Signaling, I-Chromatin Remodeling, I-Growth Factor Signaling, Ukusayinda kwe-MAPK kuyingxenye yencazelo yesiginesha ye-Waldenstrom Macroglobulinemia. Izakhi zofuzo zomdlavuza womuntu ngamunye zingahluka futhi yingakho isiginesha yabo ethile yomdlavuza ingase ihluke.

Izindlela zokwelapha ezisebenza ngempumelelo ku-Waldenstrom Macroglobulinemia zidinga ukuqaphela izindlela zesiginesha ze-biochemical yesiguli ngasinye somdlavuza kanye nomuntu osengozini yofuzo. Ngakho-ke ukwelashwa okuhlukene okunezindlela ezahlukene zezenzo kusebenza kahle ezigulini ezahlukene. Ngokufanayo futhi ngenxa yezizathu ezifanayo ukudla nezithasiselo kudingeka kube okomuntu siqu kumuntu ngamunye. Ngakho-ke okunye ukudla nezithako ezingeziwe kunconyelwe i-Waldenstrom Macroglobulinemia lapho uthatha ukwelashwa komdlavuza i-Ibrutinib, nokunye ukudla nezithako ezingeziwe akunconywa.

Imithombo efana cBioPortal kanye nezinye eziningi zinikeza idatha emele isiguli engaziwa evela ezivivinyweni zomtholampilo kuzo zonke izinkomba zomdlavuza. Le datha iqukethe imininingwane yocwaningo lomtholampilo efana nosayizi wesampula / inombolo yeziguli, amaqembu obudala, ubulili, ubuzwe, ukwelashwa, indawo yesimila nanoma yikuphi ukuguqulwa kofuzo.

I-ARID1A, IGF1R, MAP3K1 kanye ne-MYD88 yizakhi zofuzo ezikleliswe phezulu ze-Waldenstrom Macroglobulinemia. I-ARID1A ibikwa ku-100.0 % weziguli ezimele kuzo zonke izivivinyo zomtholampilo. Futhi i-IGF1R ibikwa ku-100.0%. Idatha yesiguli esihlanganisiwe ihlanganisa iminyaka ukusuka kuye kuye. I-100.0 % yemininingwane yesiguli ihlonzwa njengabesilisa. I-Waldenstrom Macroglobulinemia biology kanye nezakhi zofuzo ezibikiwe ndawonye zichaza inani labantu elimelelwe izindlela zamakhemikhali ezinto eziphilayo kulo mdlavuza. Uma izakhi zofuzo zesimila somdlavuza ngamunye noma izakhi zofuzo ezifaka engcupheni zaziwa futhi lokho kufanele kusetshenziselwe ukwenza kube ngokwakho ukudla okunomsoco.

IZIKHETHO ZOKUDLA KOKUDLA KUFANELE ZIHVANE NESIGINISHA YOMUNTU NGAMUNYE YOMDLAVUZA.

Ukudla Nezithako ze-Waldenstrom Macroglobulinemia

Kweziguli Zomdlavuza

Iziguli zomdlavuza ekwelapheni noma ekunakekelweni okudambisa umzimba zidinga ukwenza izinqumo ngokudla nezithako ezisizayo - zama-kilojoule okudla adingekayo, zokulawula noma yimiphi imiphumela emibi yokwelashwa kanye nokuphathwa komdlavuza okuthuthukisiwe. Konke ukudla okusekelwe ezitshalweni akulingani futhi ukukhetha nokubeka phambili ukudla okuqondene nomuntu siqu futhi okwenziwe ngokwezifiso ekwelashweni komdlavuza okuqhubekayo kubalulekile futhi kuyinkimbinkimbi. Nazi izibonelo ezinikeza imihlahlandlela yokwenza izinqumo zokudla okunomsoco.

Khetha AMAQHAFU E-CHICORY Yemifino noma I-WINTER SQUASH?

I-Vegetable Chicory Leaves iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Chlorogenic Acid, i-Gallic Acid, i-Isoliquiritigenin, i-Curcumin, i-Apigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. I-Chicory Leaves inconyelwe i-Waldenstrom Macroglobulinemia lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib. Lokhu kungenxa yokuthi Amaqabunga e-Chicory aguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ibrutinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yaseWinter Squash yiChlorogenic Acid, Protocatechuic Acid, Isoliquiritigenin, Apigenin, Curcumin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. I-Winter Squash ayinconyelwe i-Waldenstrom Macroglobulinemia uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

AMAKHAMBA E-CHICORY YEZIBONGO KUNCONYWA NGESIKHATHI SESIKHATHI SASEBUSIKA KU-Waldenstrom Macroglobulinemia KANYE NOKWELASHWA I-Ibrutinib.

Khetha Isithelo IPEAR noma IGRAPEFRUIT?

I-Fruit Pear iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Chlorogenic Acid, i-Gallic Acid, i-Isoliquiritigenin, i-Curcumin, i-Genistein. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. Ipheya liyanconywa ku-Waldenstrom Macroglobulinemia lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib. Lokhu kungenxa yokuthi i-Pear ilungisa lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ibrutinib.

Ezinye zezithako ezisebenzayo noma ama-bioactive esithelweni I-Grapefruit yi-Chlorogenic Acid, i-Ferulic Acid, i-Curcumin, i-Isoliquiritigenin, i-Delphinidin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. I-Grapefruit ayinconyelwe i-Waldenstrom Macroglobulinemia uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungaphenduli kahle.

IPEAR LESITHELO KUNCONYWA NGAPHEZU KWEGILIPISI KU-Waldenstrom Macroglobulinemia KANYE NOKWELASHWA I-Ibrutinib.

Khetha Nut WALNUT noma JAPANESE WALNUT?

I-Walnut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Carvacrol, i-Chlorogenic Acid, i-Protocatechuic Acid, i-Curcumin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. I-Walnut inconywa nge-Waldenstrom Macroglobulinemia lapho ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib. Lokhu kungenxa yokuthi i-Walnut iguqula lezo zindlela ze-biochemical eziye zabikwa ngokwesayensi ukuze ziqwashise umthelela we-Ibrutinib.

Ezinye zezithako ezisebenzayo noma ama-bioactives ku-Walnut yaseJapane yi-Chlorogenic Acid, i-Protocatechuic Acid, i-Apigenin, i-Curcumin, i-Isoliquiritigenin. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-NFKB Signaling nezinye. I-Walnut yaseJapane ayinconyelwe i-Waldenstrom Macroglobulinemia uma ukwelashwa komdlavuza okuqhubekayo kuyi-Ibrutinib ngoba ilungisa lezo zindlela zamakhemikhali ezinto eziphilayo ezenza ukwelashwa komdlavuza kungazweli noma kungasabeli kahle.

I-WALNUT INCONYISWA NGE-WALNUT YASE-JAPANESE NGE-Waldenstrom Macroglobulinemia KANYE NOKWELASHWA I-Ibrutinib.

Kubantu abaneGenetic Risk of Cancer

Umbuzo obuzwa abantu abasengozini yofuzo ye-Waldenstrom Macroglobulinemia noma umlando womndeni uthi “Yini Okufanele Ngiyidle Ngokuhlukile Kunangaphambili?” nokuthi kufanele bakukhethe kanjani ukudla kanye nezithako ukuze balawule ubungozi besifo. Njengoba engcupheni yomdlavuza akukho okungenziwa mayelana nokwelashwa - izinqumo zokudla nezithako zibalulekile futhi kube ngenye yezinto ezimbalwa kakhulu ezingenziwa. Konke ukudla okusekelwe ezitshalweni akulingani futhi kusekelwe kufuzo oluhlonziwe kanye nesiginesha yendlela - ukukhetha kokudla kanye nezithako kufanele kube okomuntu siqu.

Khetha I-Vegetable GIANT BUTTERBUR noma isipinashi se-MUSTARD?

I-Vegetable Giant Butterbur iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Giant Butterbur inconyelwa engcupheni ye-Waldenstrom Macroglobulinemia lapho ubungozi bofuzo obuhlobene buyi-ARID1A. Lokhu kungenxa yokuthi i-Giant Butterbur inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives emifino yesipinashi yesinaphi yi-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Epithelial kuya ku-Mesenchymal Transition, i-WNT Beta Catenin Signaling kanye ne-NFKB Signaling nezinye. I-Mustard Spinach ayinconywa uma ingozi ye-Waldenstrom Macroglobulinemia uma ingozi yofuzo ehlotshaniswa nayo i-ARID1A ngoba inyusa izindlela zayo zokusayina.

IBUTTERBUR ENKULU YEZINJINI INCONYWA NGENXA KWESIPINSHI SEMISTARD NGENGOZI YOFUZO YOMFUZA KA-ARID1A.

Khetha Isithelo JAVA PLUM noma PUMMELO?

I-Fruit Java Plum iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Java Plum inconyelwa engcupheni ye-Waldenstrom Macroglobulinemia uma ingozi yofuzo ehlotshaniswa nayo iyi-ARID1A. Lokhu kungenxa yokuthi i-Java Plum inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactives esithelweni i-Pummelo yi-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Epithelial kuya ku-Mesenchymal Transition kanye ne-WNT Beta Catenin Signaling nezinye. I-Pummelo ayinconywa uma ingozi ye-Waldenstrom Macroglobulinemia uma ingozi yofuzo ehlotshaniswa nayo i-ARID1A ngoba inyusa izindlela zayo zokusayina.

ISITHELO I-JAVA PLUM INCONYISWA NGAPHEZU KWE-PUMMELO NGENGOZI YOFUZO YE-ARID1A YOMKHANZA.

Khetha Nut BUTTERNUT noma FLXSEED?

I-Butternut iqukethe izithako eziningi ezisebenzayo noma ama-bioactives afana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Lycopene. Lezi zithako ezisebenzayo zilawula izindlela ezahlukahlukene ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK Signaling kanye ne-MYC Signaling nezinye. I-Butternut inconywa engcupheni ye-Waldenstrom Macroglobulinemia uma ingozi yofuzo ehlotshaniswa nayo i-ARID1A. Lokhu kungenxa yokuthi i-Butternut inyusa lezo zindlela ze-biochemical eziphikisana nezishayeli zesiginesha zayo.

Ezinye zezithako ezisebenzayo noma ama-bioactive ku-Flaxseed yi-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Lezi zithako ezisebenzayo zikhohlisa izindlela ezihlukene ze-biochemical ezifana ne-MAPK Signaling, Epithelial to Mesenchymal Transition, WNT Beta Catenin Signaling kanye ne-PI3K-AKT-MTOR Signaling nezinye. I-Flaxseed ayinconywa uma ingozi ye-Waldenstrom Macroglobulinemia uma ingozi yofuzo ehlotshaniswa nayo i-ARID1A ngoba inyusa izindlela zayo zokusayina.

I-BUTTERNUT INCONYISWA NGAPHEZU KWE-FLEXSEED NGENGOZI YOFUZO YE-ARID1A YOMKHANZA.

Ekuphetheni

Ukudla Nezithako ezikhethiwe izinqumo ezibalulekile zomdlavuza njenge-Waldenstrom Macroglobulinemia. Iziguli ze-Waldenstrom Macroglobulinemia kanye nabantu abasengozini yofuzo bahlala benalo mbuzo: “Yikuphi ukudla nezithasiselo zokudla okunempilo engikunconyelwe futhi okungekona?” Kunenkolelo evamile okuwumbono oyiphutha wokuthi konke ukudla okusekelwe ezitshalweni kungaba yinzuzo noma cha kodwa ngeke kube yingozi. Ukudla okuthile kanye nezithako zokudla kungaphazamisa ukwelashwa komdlavuza noma kukhuthaze abashayeli bendlela yamangqamuzana omdlavuza.

Kunezinhlobo ezahlukene zezinkomba zomdlavuza ezifana ne-Waldenstrom Macroglobulinemia, ngayinye inezakhi zofuzo zesimila ezihlukile ngokuhlukahluka kofuzo kumuntu ngamunye. Ngaphezu kwalokho konke ukwelashwa komdlavuza kanye ne-chemotherapy kunendlela ehlukile yokusebenza. Ukudla ngakunye okufana namaqabunga e-Chicory kuqukethe ama-bioactives ahlukahlukene ngamanani ahlukene, anomthelela kumasethi ahlukene nahlukile wezindlela ze-biochemical. Incazelo yokondleka komuntu siqu izincomo zokudla komuntu ngamunye zezinkomba zomdlavuza, ukwelashwa, izakhi zofuzo, indlela yokuphila nezinye izici. Izinqumo zokudla okunomsoco zomdlavuza zidinga ulwazi lwebhayoloji yomdlavuza, isayensi yokudla kanye nokuqonda izindlela zokwelapha ezihlukene ze-chemotherapy. Ekugcineni uma kukhona izinguquko zokwelashwa noma ukuhlonzwa kwe-genomics entsha - ukwenza kube ngokwakho ukudla okunomsoco kudinga ukuhlolwa kabusha.

Isixazululo somuntu siqu somsoco we-addon senza ukwenza izinqumo kube lula futhi sisuse konke ukuqagela ekuphenduleni umbuzo, "Yikuphi ukudla okufanele ngikukhethe noma ngingakukhetheli i-Waldenstrom Macroglobulinemia?". Ithimba le-addon elixube izigwegwe eziningi lihlanganisa odokotela bomdlavuza, ososayensi bezokwelapha, onjiniyela bezinhlelo zokusebenza nososayensi bedatha.

Okubhekwayo

• I-Msk Impact 2017
• Isimo esiguquguqukayo somdlavuza we-metastatic sivezwe kusukela ekulandeleni okungase kube khona kweziguli eziyi-10,000.
• Ukuvinjelwa kwe-Chlorogenic-induced of non-small cancer cells kwenzeka ngokulawulwa kwe-histone deacetylase 6.
• I-Curcumin ivimbela ukukhula ngendlela ye-Wnt/β-catenin kumaseli omdlavuza wamaphaphu angewona amancanyana.
• I-Paederia foetida idala umsebenzi wokulwa nomdlavuza ngokushintsha ama-enzyme okuguqula i-chromatin futhi iguqule ukubonakaliswa kwezakhi zofuzo ze-cytokine ezinokuvuvukala kumaseli omdlavuza wendlala yesinye.
• I-Betulinic Acid Icindezela I-Metastasis Yomdlavuza Webele ngokukhomba i-GRP78-Mediated Glycolysis kanye ne-ER Stress Apoptotic Pathway.
• I-Vitamin C ithuthukisa ukuguqulwa kwe-epigenetic okubangelwa i-5-azacytidine kanye nokuboshwa komjikelezo weseli kumigqa yeseli ye-hepatocellular carcinoma i-HLE ne-Huh7.
• https://emedicine.medscape.com/article/207097-overview
• https://my.clevelandclinic.org/health/diseases/17951-waldenstrom-macroglobulinemia
• https://www.mayoclinic.org/diseases-conditions/waldenstrom-macroglobulinemia/symptoms-causes/syc- 20359967