Ngowuphi umhlaza onokuzuza ngokubandakanya iBlueberry kwisidlo sabo?

Iimbalasane

I-Blueberry yamkelwa ngokubanzi ngezibonelelo zayo zempilo kwaye isetyenziswa rhoqo ngabaguli abanomhlaza kunye nabo basengozini yemfuza. Nangona kunjalo, ukhuseleko kunye nokusebenza kweBlueberry kwizigulana ezinomhlaza kuxhomekeke kwizinto ezininzi ezinjengomhlaza, ichemotherapy, olunye unyango, kunye nemfuza yethumba. Ukwazi ukuba ezinye ukutya kunye nezongezelelo, ezinje ngegrapefruit kunye nesipinatshi, zinokusebenzisana kakubi namayeza omhlaza kwaye zibangele ukusabela okubi kubalulekile.

Ukutya kubaluleke kakhulu kunyango lomhlaza njengoko kunokuchaphazela iziphumo zonyango. Izigulana ezinomhlaza kufuneka zikhethe ngononophelo kwaye zifake ukutya okufanelekileyo kunye nezongezo kwizidlo zabo. Umzekelo, iBlueberry inokuba luncedo kwabo banePrayimari yePenile Squamous Cell Carcinoma ephantsi kweMitomycin, kodwa isenokungabi ilungile kwizigulana ezifumana iRadiation yePrimary Adamantinoma. Ngaphaya koko, ngelixa iBlueberry inokunceda abantu abanomngcipheko wemfuza "ERBB2", ayinakucetyiswa kwabo banomngcipheko wemfuzo owahlukileyo "ATM". Ukwenza izicwangciso zokutya ezisekelwe kwimpilo, unyango, kunye nofuzo kubalulekile.

Ukuqonda ukuba ukwenza isigqibo malunga nokufaneleka kweBlueberry kwisigulana somhlaza kufuneka sibe ngumntu ngamnye kubalulekile. Izinto ezibalulekileyo ezifana nohlobo lomhlaza, iindlela zonyango, ukwakheka kwemfuzo, umngcipheko wemfuza, ubudala, ubunzima bomzimba, kunye nendlela yokuphila zibalulekile ekwenzeni isigqibo sokuba iBlueberry lukhetho olufanelekileyo. I-Genomics kunye ne-genomics, ngokukodwa, yingqwalasela ebalulekileyo. Kuba ezi zinto zinokuvela, kubalulekile ukuphonononga rhoqo kwaye ulungelelanise ukhetho lokutya ukuhambelana notshintsho kwisimo sempilo kunye nonyango.

Ukuqukumbela, indlela epheleleyo yokhetho lokutya ibalulekile, igxile kwiziphumo ezipheleleyo zazo zonke izinto ezisebenzayo ekutyeni / nezongezo ezifana neBlueberry endaweni yokuvavanya isithako ngasinye esisebenzayo ngokwahlukileyo okanye ukungayinaki ngokupheleleyo. Lo mbono ubanzi ukhuthaza indlela enengqiqo nenzululwazi kwisicwangciso sokutya somhlaza.

Uluhlu olufutshane

Ukusetyenziswa kokutya okusekelwe kwizityalo kunye nezongezelelo, ezinje ngeevithamini, imifuno, iiminerali, iiprobiotics, kunye nezongezelelo ezahlukeneyo ezikhethekileyo, ziyenyuka phakathi kwabaguli abanomhlaza. Ezi zongezo ziyilelwe ukuhambisa ugxininiso oluphezulu lwezithako ezithile ezisebenzayo, uninzi lwazo zikwakukutya okwahlukeneyo. Ugxininiso kunye nokwahlukana kwezithako ezisebenzayo ziyahluka phakathi kokutya okupheleleyo kunye nezongezelelo. Ukutya ngokuqhelekileyo kunika uluhlu lwezithako ezisebenzayo kodwa kwiindawo ezisezantsi, ngelixa izongezelelo zibonelela ngoxinzelelo oluphezulu lwezithako ezithile.

Ukuthathela ingqalelo imisebenzi eyahlukeneyo yesayensi kunye neyebhayoloji yesithako ngasinye esisebenzayo kwinqanaba leemolekyuli, kubalulekile ukunika ingxelo ngeziphumo ezidityanisiweyo zala malungu xa uthatha isigqibo malunga nokutya kunye nezongezo eziza kutyiwa okanye hayi.

Umbuzo obalulekileyo uvela: Ngaba kufuneka udibanise iBlueberry kwisidlo sakho njengento yokutya okanye isongezelelo? Ngaba kuyacetyiswa ukuba utye iBlueberry ukuba unemfuza ekhokelela kumhlaza onxulumene ne-ERBB2 gene? Kuthekani ukuba endaweni yoko umngcipheko wakho wemfuza uvela kwijene ye-ATM? Ngaba kunenzuzo ukubandakanya iBlueberry ekutyeni kwakho ukuba ufunyaniswe une-Adantinoma ePhambili, okanye ukuba uxilongo lwakho luyiPrimary Penile Squamous Cell Carcinoma? Ngaphezu koko, kufuneka kuhlengahlengiswe njani ukusetyenziswa kwakho kweBlueberry ukuba ufumana unyango lweMitomycin okanye ukuba isicwangciso sakho sonyango siyatshintsha sisuka kwiMitomycin siye kwiRadiation? Kubalulekile ukuqaphela ukuba iinkcazo ezilula ezifana 'neBlueberry yindalo, ngoko isoloko iluncedo' okanye 'iBlueberry ibomeleza ukhuselo lomzimba' ayonelanga kukhetho lokutya / lokongezelela.

Ukongeza, kubalulekile ukuvavanya kwakhona ukufaneleka kokubandakanya iBlueberry kwisidlo sakho ukuba kukho utshintsho kwirejimeni yonyango lwakho. Ngamafutshane, xa usenza izigqibo malunga nokubandakanya ukutya okanye izongezo ezinje ngeBlueberry kwisidlo sakho ngezibonelelo zayo, kuya kufuneka uqwalasele iziphumo ezipheleleyo ze-biochemical yazo zonke izithako, uqwalasele izinto ezifana nohlobo lomhlaza, unyango oluthile olwenzayo, i-genetic predispositions. , kunye nokukhetha indlela yokuphila.

Cancer

Umhlaza usengumceli mngeni obalulekileyo kwicandelo lezonyango, ngokufuthi ubangela unxunguphalo oluxhaphakileyo. Nangona kunjalo, ukuqhubela phambili kwamva nje kuye kwaphucula iziphumo zonyango, ngakumbi ngeendlela zonyango zomntu, iindlela zokujonga ezingaphazamisiyo kusetyenziswa igazi kunye neesampulu zamathe, kunye nophuhliso lwe-immunotherapy. Ukufunyaniswa kwangethuba kunye nokungenelela kwangethuba kuye kwaba yinto ebalulekileyo ekuphembeleleni ngokufanelekileyo iziphumo zonyango ngokubanzi.

Uvavanyo lwemfuzo lunikeza isithembiso esibalulekileyo ekuvavanyeni umngcipheko womhlaza kunye nokuba sesichengeni kwangoko. Nangona kunjalo, kubantu abaninzi abaneemeko zosapho kunye nemfuzo kumhlaza, ukhetho longenelelo lonyango, nokuba lubekwe esweni rhoqo, luhlala lulinganiselwe okanye alukho. Nje ukuba kufunyaniswe ukuba unohlobo oluthile lomhlaza, njengePrimary Penile Squamous Cell Carcinoma okanye i-Primary Adamantinoma, izicwangciso zonyango kufuneka zenziwe ngokwezifiso ngokusekwe kwi-tumor genetics yomntu, inqanaba lesi sifo, kunye nezinto ezifana nobudala kunye nesini.

Emva konyango, ukubeka iliso okuqhubekayo kubalulekile ukuze kubonwe naziphi na iimpawu zokubuyela kwakhona komhlaza kunye nokwazisa izigqibo ezilandelayo. Uninzi lwezigulana ezinomhlaza kunye nabo basemngciphekweni bahlala befuna iingcebiso malunga nokubandakanya ukutya okuthile kunye nezongezo kwizidlo zabo, ezidlala indima ebalulekileyo kwinkqubo yabo yokuthatha isigqibo malunga nolawulo lwezempilo.

Umbuzo obalulekileyo ngowokuba ingaba kubandakanyeka kwimingcipheko yemfuza kunye noxilongo oluthile lomhlaza xa uthatha isigqibo malunga nokhetho lokutya, olufana neBlueberry. Ngaba umngcipheko wemfuzo womhlaza osuka kutshintsho kwi-ERBB2 unefuthe elifanayo le-biochemical pathway njengokuguqulwa kwe-ATM? Ukusuka kwimbono yesondlo, ngaba umngcipheko ohambelana nePrayimari yePenile Squamous Cell Carcinoma ilingana nePrimary Adamantinoma? Ngaphaya koko, ngaba uqwalaselo lokutya luhlala lufana kwabo baphantsi kweRadiation njengabo bafumana iMitomycin? Ezi ngqwalasela zibalulekile ekwenzeni ukhetho lokutya olunolwazi lwabantu abaneengozi ezahlukeneyo zemfuza kunye nonyango lomhlaza.

I-Blueberry - Isongezo seSondlo

I-Blueberry eyongezelelweyo iquka uluhlu lwezithako ezisebenzayo, ezibandakanya i-Vitamin C, i-Gallic Acid, i-Cianidanol kunye ne-Chlorogenic Acid, nganye ekhoyo kwiindawo ezahlukeneyo. Ezi zithako ziphembelela iindlela ze-molecular, ngokukodwa i-PI3K-AKT-MTOR Ukubonakaliswa, Uxinzelelo lwe-Oxidative, i-P53 Signaling kunye ne-RAS-RAF Signaling, elawula imiba ebalulekileyo yomhlaza kwinqanaba leeselula, ezifana nokukhula kwe-tumor, ukusasazeka, kunye nokufa kweeseli. Ukunikezelwa kwale mpembelelo yebhayoloji, ukukhetha izongezo ezifanelekileyo njengeBlueberry, iyodwa okanye ngokudibeneyo, iba sisigqibo esibalulekileyo kumxholo wesondlo somhlaza. Xa ucinga ukusebenzisa iBlueberry kumhlaza, kubalulekile ukuqwalasela ezi zinto zihlukeneyo kunye neendlela. Oku kungenxa yokuba, ngokufana nonyango lomhlaza, ukusetyenziswa kweBlueberry ayisosigqibo sehlabathi lonke esifanelekileyo kubo bonke abanomhlaza kodwa kufuneka senziwe umntu.

Ukukhetha izongezo zeBlueberry

Ukujongana nombuzo othi 'Ndifanele ndiyiphephe nini iBlueberry kwimeko yoMhlaza' kulucelomngeni kuba impendulo ixhomekeke kakhulu kumntu ngamnye - ngokulula 'Kuxhomekeke!'. Ngokufana nendlela naluphi na unyango lomhlaza olunokuthi lungasebenzi kwisigulana ngasinye, ukubaluleka kunye nokhuseleko okanye iinzuzo zeBlueberry ziyahluka ngokuxhomekeke kwiimeko zomntu. Izinto ezifana nohlobo oluthile lomhlaza, i-genetic predispositions, unyango lwangoku, ezinye izongezo ezithathwayo, indlela yokuphila, i-BMI, kunye nayo nayiphi na i-allergies yonke idlala indima ekunqumeni ukuba iBlueberry ifanelekile okanye kufuneka igwenywe, igxininisa ukubaluleka koqwalaselo lomntu izigqibo ezinjalo.

1. Ngaba i-Blueberry Supplements iyakunceda kwi-Primary Adamantinoma Patients eziphantsi konyango lweRadiation?

I-Adamantinoma eyiprayimari ibonakaliswe ngokuguqulwa kofuzo oluthile, oku kukuthi i-ARHGAP45, i-PI4KB kunye ne-SDSL, ekhokelela kwiinguqu kwiindlela ze-biochemical, ngokukodwa i-Oxidative Stress kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, okufana neRadiation, kuxhomekeke kwindlela yayo yokusebenza kwezi ndlela zikhethekileyo. Esona sicwangciso sifanelekileyo siquka ukulungelelanisa isenzo sonyango kunye neendlela eziqhuba umhlaza, ngaloo ndlela kuqinisekiswa indlela yobuqu nesebenzayo. Kwiimeko ezinjalo, ukuphepha ukutya okanye izongezo zesondlo ezinokuchasa iziphumo zonyango okanye ukunciphisa olu lungelelwaniso kubalulekile. Ngokomzekelo, i-Blueberry supplement, echaphazela i-Oxidative Stress, ayinakuba yinto efanelekileyo yokukhetha kwimeko ye-Primary Adamantinoma xa i-Radiation. Oku kungenxa yokuba isenokuthi iqhubele phambili ngakumbi isifo okanye iphazamise ukusebenza konyango. Xa ukhetha isicwangciso sesondlo, kubalulekile ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluqhubekayo, ubudala, isini, i-BMI, indlela yokuphila, kunye naluphi na utshintsho lwemfuza olwaziwayo.

2. Ngaba i-Blueberry Supplements iya kunceda i-Primary Penile Squamous Cell Carcinoma Izigulana eziphantsi koNyango lwe-Mitomycin?

I-Primary Penile Squamous Cell Carcinoma ichongiwe ngokuguqulwa kofuzo oluthile, njenge-ABRAXAS1, PIK3CB kunye ne-NUP93, ebangela utshintsho kwiindlela ze-biochemical pathways, ngokukodwa i-PI3K-AKT-MTOR Ukubonakaliswa, i-Hematopoiesis kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, njengeMitomycin, kumiselwa kukudibana kwayo nezi ndlela. Injongo kukuqinisekisa ukuba unyango luhambelana kakuhle neendlela eziqhuba umhlaza, okwenza kube nendlela yonyango lomntu. Kulo mxholo, ukutya okanye izongezo ezihambelana nonyango okanye ukuphucula oku kulungelelaniswa kufuneka kuthathelwe ingqalelo. Ngokomzekelo, isongezelelo seBlueberry lukhetho olunengqiqo kwabo banePrayimari yePenile Squamous Cell Carcinoma ehamba neMitomycin. Oku kungenxa yokuba iBlueberry inefuthe kwiindlela ezifana ne-PI3K-AKT-MTOR Umqondiso, onokuthi uthintele izinto eziqhuba i-Primary Penile Squamous Cell Carcinoma okanye uzuze ukusebenza kweMitomycin.

3

Iinkampani ezahlukeneyo zibonelela ngeephaneli zemfuza zokuvavanya umngcipheko wemfuza weentlobo ezahlukeneyo zomhlaza. Ezi panels ziquka imizila yemfuza enxulunyaniswa nebele, i-ovarian, i-uterine, i-prostate, kunye nomhlaza wesisu. Ukuvavanya ezi genes kunokuqinisekisa ukuxilongwa kunye nokwazisa unyango kunye nezicwangciso zokulawula. Ukuchonga umahluko obangela isifo kunokuncedisa ngakumbi ekuvavanyeni nasekuxilongweni kwezalamane ezinokuba sengozini. Ufuzo lwe-ATM luqhele ukubandakanywa kwezi panels zovavanyo lomngcipheko womhlaza.

Ukuguqulwa kwe-ATM gene kuchaphazela iindlela ze-biochemical okanye iinkqubo, ezifana ne-P53 Signaling kunye ne-DNA Repair, ezibandakanyeka ngokuthe ngqo okanye ngokungathanga ngqo ekuqhubeni umhlaza kwinqanaba le-molecular. Xa iphaneli yofuzo ichonga uguquko kwi-ATM ehambelana nomngcipheko owongeziweyo we-Chronic Myelomonocytic Leukemia, ingqiqo yesayensi icebisa ukuphepha ukusetyenziswa kweBlueberry. Oku kungenxa yokuba ukongeza i-Blueberry inefuthe kwiindlela ezifana ne-P53 Signaling, enokukhokelela kwimiphumo emibi kumxholo wenguqu ye-ATM kunye neemeko zomhlaza ezinxulumene nazo.

4. Ngaba izongezo zeBlueberry zikhuselekile kubantu abasempilweni abane-ERBB2 Mutation Associated Genetic Risk?

I-ERBB2 idlala indima ebalulekileyo kuvavanyo lomngcipheko womhlaza. Ukuguqulwa kwe-ERBB2 kunokuphazamisa iindlela ezibalulekileyo ze-biochemical, ezibandakanya i-RAS-RAF Signaling, i-Growth Factor Signaling kunye ne-PI3K-AKT-MTOR Signaling, echaphazela ukuphuhliswa komhlaza. Ukuba iphaneli yakho yemfuza ityhila utshintsho kwi-ERBB2 ehambelana ne-Esophageal Adenocarcinoma, cinga ukufaka izongezo zeBlueberry kwisicwangciso sakho sesondlo. Ezi zongezo zinokuphembelela kakuhle iindlela ezifana ne-RAS-RAF Signaling, inzuzo ngokubonelela ngenkxaso efanelekileyo kubantu abanokuguqulwa kwe-ERBB2 kunye neenkxalabo zempilo ezinxulumene nazo.

Ukuququmbela

Ezona zinto zimbini zibalulekileyo ekufuneka uzikhumbule kukuba unyango lomhlaza kunye nesondlo azinakuze zifane kumntu wonke. Isondlo, kuquka ukutya kunye nezongezelelo ezifana neBlueberry, sisixhobo esisebenzayo esinokulawulwa nguwe ngelixa ujongene nomhlaza.

"Ndingatya ntoni?" ngowona mbuzo udla ngokubuzwa ngabaguli abanomhlaza kunye nabo basemngciphekweni womhlaza. Impendulo echanekileyo kukuba ixhomekeke kwizinto ezifana nohlobo lomhlaza, imfuzo yethumba, unyango lwangoku, ukungezwani komzimba, indlela yokuphila, kunye ne-BMI.

Fumana isondlo sakho somhlaza kwi-addon ngokucofa ikhonkco elingezantsi kwaye uphendule imibuzo malunga nohlobo lomhlaza wakho, unyango, indlela yokuphila, i-allergies, ubudala, kunye nesini.

Ucaphulo

• Indima ye-KEAP1/NRF2 kunye ne-TP53 yoGuquko kwiLung Squamous Cell Carcinoma Development kunye noKuchasana neRadiation.
• cBioPortal for Cancer Genomics
• I-Polyphenol yendalo ye-Chlorogenic Acid ikhusela kwi-Acetaminophen-Induced Hepatotoxicity ngokuSebenza i-ERK / Nrf2 Indlela ye-Antioxidative.
• I-Cytotoxicity kunye ne-apoptosis yokungeniswa kwi-adenocarcinoma yesifuba somntu iiseli ze-MCF-7 ngu (+) -cyanidan-3-ol.
• I-Chlorogenic acid inqanda ukwanda kwaye ibangela i-apoptosis kwi-A498 yeeseli zomhlaza wezintso zomntu ngendlela engasebenziyo ye-PI3K/Akt/mTOR yokubonisa indlela.
• cBioPortal for Cancer Genomics
• Uhlalutyo lwe-molecular docking ye-Cianidanol esuka kwi-Ginkgo biloba kunye ne-HER2 + ekujoliswe kuyo kumhlaza webele.
• I-HyperFoods: Imephu ekrelekrele yomatshini yeemolekyuli ezibetha umhlaza ekutyeni.
• Uhlalutyo lwe-pan-cancer lwe-genomes epheleleyo.
• Ukubonakaliswa kwe-epidermal growth factor receptors kwi-astrocytic glial kunye neeseli ze-neuronal kwinkcubeko yokuqala.
• Unyango lomhlaza lubumba ubume bokuqina be-clonal hematopoiesis.