Ngowuphi umhlaza onokuthi uxhamle ngokubandakanya iBaicalin ekutyeni kwabo?

Iimbalasane

I-Baicalin yaziwa ngokubanzi ngeenzuzo zayo zempilo kwaye isetyenziswa rhoqo ngabaguli abanomhlaza kunye nabo basengozini yemfuzo. Nangona kunjalo, ukhuseleko kunye nokusebenza kakuhle kweBaicalin kwizigulana ezinomhlaza kuxhomekeke kwizinto ezininzi ezinjengomhlaza, ichemotherapy, olunye unyango, kunye nemfuza yethumba. Ukwazi ukuba ezinye ukutya kunye nezongezelelo, ezinje ngegrapefruit kunye nesipinatshi, zinokusebenzisana kakubi namayeza omhlaza kwaye zibangele ukusabela okubi kubalulekile.

Ukutya kubaluleke kakhulu kunyango lomhlaza njengoko kunokuchaphazela iziphumo zonyango. Izigulana ezinomhlaza kufuneka zikhethe ngononophelo kwaye zifake ukutya okufanelekileyo kunye nezongezo kwizidlo zabo. Umzekelo, i-Baicalin inokuzuza abo bane-Primary Glioblastoma ephantsi kwe-Temozolomide, kodwa isenokungabi ilungile kwizigulana ezifumana i-Adriamycin ye-Primary Papillary Thyroid Cancer. Ngaphaya koko, ngexa i-Baicalin inokunceda abantu abanomngcipheko wemfuzo “TERT”, ayinakucetyiswa kwabo banengozi yemfuzo eyahlukileyo”. Ukwenza izicwangciso zokutya ezisekelwe kwimpilo, unyango, kunye nofuzo kubalulekile.

Ukuqonda ukuba ukwenza isigqibo malunga nokufaneleka kwe-Baicalin kwisigulana somhlaza kufuneka sibe ngumntu ngamnye kubalulekile. Izinto ezibalulekileyo ezifana nohlobo lomhlaza, iindlela zonyango, ukwakheka kwemfuzo, imingcipheko yemfuza, ubudala, ubunzima bomzimba, kunye nendlela yokuphila zibalulekile ekwenzeni isigqibo sokuba iBaicalin lukhetho olufanelekileyo. I-Genomics kunye ne-genomics, ngokukodwa, yingqwalasela ebalulekileyo. Kuba ezi zinto zinokuvela, kubalulekile ukuphonononga rhoqo kwaye ulungelelanise ukhetho lokutya ukuhambelana notshintsho kwisimo sempilo kunye nonyango.

Ukuqukumbela, indlela epheleleyo yokhetho lokutya ibalulekile, ijolise kwiziphumo ezipheleleyo zazo zonke iinxalenye ezisebenzayo kukutya / izongezo ezifana ne-Baicalin endaweni yokuvavanya isithako ngasinye esisebenzayo ngokwahlukileyo okanye ukungayinaki ngokupheleleyo. Lo mbono ubanzi ukhuthaza indlela enengqiqo nenzululwazi kwisicwangciso sokutya somhlaza.

Uluhlu olufutshane

Ukusetyenziswa kokutya okusekelwe kwizityalo kunye nezongezelelo, ezinje ngeevithamini, imifuno, iiminerali, iiprobiotics, kunye nezongezelelo ezahlukeneyo ezikhethekileyo, ziyenyuka phakathi kwabaguli abanomhlaza. Ezi zongezo ziyilelwe ukuhambisa ugxininiso oluphezulu lwezithako ezithile ezisebenzayo, uninzi lwazo zikwakukutya okwahlukeneyo. Ugxininiso kunye nokwahlukana kwezithako ezisebenzayo ziyahluka phakathi kokutya okupheleleyo kunye nezongezelelo. Ukutya ngokuqhelekileyo kunika uluhlu lwezithako ezisebenzayo kodwa kwiindawo ezisezantsi, ngelixa izongezelelo zibonelela ngoxinzelelo oluphezulu lwezithako ezithile.

Ukuthathela ingqalelo imisebenzi eyahlukeneyo yesayensi kunye neyebhayoloji yesithako ngasinye esisebenzayo kwinqanaba leemolekyuli, kubalulekile ukunika ingxelo ngeziphumo ezidityanisiweyo zala malungu xa uthatha isigqibo malunga nokutya kunye nezongezo eziza kutyiwa okanye hayi.

Umbuzo obalulekileyo uvela: Ngaba kufuneka udibanise iBaicalin kwisidlo sakho njengento yokutya okanye isongezelelo? Ngaba kuyacetyiswa ukuba utye i-Baicalin ukuba unemfuzo enokuthanani nomhlaza onxulunyaniswa nofuzo lwe-TERT? Kuthekani ukuba endaweni yoko umngcipheko wakho wemfuza usuka kumfuza? Ngaba kuluncedo ukuquka i-Baicalin ekutyeni kwakho ukuba ngaba ufunyaniswe unomhlaza wePapillary Thyroid, okanye ukuba uxilongo lwakho yi-Primary Glioblastoma? Ngaphezu koko, ukusetyenziswa kwakho kwe-Baicalin kufuneka kuhlengahlengiswe njani ukuba ufumana unyango lwe-Temozolomide okanye ukuba isicwangciso sakho sonyango sitshintsha ukusuka kwi-Temozolomide ukuya kwi-Adriamycin? Kubalulekile ukuqonda ukuba iinkcazo ezilula ezifana 'ne-Baicalin yendalo, ngoko ke isoloko iluncedo' okanye 'i-Baicalin yonyusa ukhuselo lomzimba' akonelanga kukhetho lokutya/ lokongezelela.

Ukongeza, kubalulekile ukuvavanya kwakhona ukufaneleka kokubandakanya i-Baicalin kwisidlo sakho ukuba kukho utshintsho kwirejimeni yonyango lwakho. Isishwankathelo, xa usenza izigqibo malunga nokubandakanya ukutya okanye izongezo ezifana ne-Baicalin kwisidlo sakho ngezibonelelo zayo, kuya kufuneka uqwalasele iziphumo ze-biochemical yazo zonke izithako, uqwalasele izinto ezifana nohlobo lomhlaza, unyango oluthile olwenzayo, i-genetic predispositions. , kunye nokukhetha indlela yokuphila.

Cancer

Umhlaza usengumceli mngeni obalulekileyo kwicandelo lezonyango, ngokufuthi ubangela unxunguphalo oluxhaphakileyo. Nangona kunjalo, ukuqhubela phambili kwamva nje kuye kwaphucula iziphumo zonyango, ngakumbi ngeendlela zonyango zomntu, iindlela zokujonga ezingaphazamisiyo kusetyenziswa igazi kunye neesampulu zamathe, kunye nophuhliso lwe-immunotherapy. Ukufunyaniswa kwangethuba kunye nokungenelela kwangethuba kuye kwaba yinto ebalulekileyo ekuphembeleleni ngokufanelekileyo iziphumo zonyango ngokubanzi.

Uvavanyo lwemfuzo lunikeza isithembiso esibalulekileyo ekuvavanyeni umngcipheko womhlaza kunye nokuba sesichengeni kwangethuba. Nangona kunjalo, kubantu abaninzi abaneemeko zosapho kunye nemfuzo kumhlaza, ukhetho longenelelo lonyango, nokuba lubekwe esweni rhoqo, luhlala lulinganiselwe okanye lungabikho. Nje ukuba kufunyaniswe ukuba unohlobo oluthile lomhlaza, onje ngePrimary Glioblastoma okanye iPrimary Papillary Thyroid Cancer, iindlela zonyango kufuneka zenziwe ngokwezifiso ngokusekwe kwi-tumor genetics yomntu, inqanaba lesi sifo, kunye nezinto ezifana nobudala kunye nesini.

Emva konyango, ukubeka iliso okuqhubekayo kubalulekile ukuze kubonwe naziphi na iimpawu zokubuyela kwakhona komhlaza kunye nokwazisa izigqibo ezilandelayo. Uninzi lwezigulana ezinomhlaza kunye nabo basemngciphekweni bahlala befuna iingcebiso malunga nokubandakanya ukutya okuthile kunye nezongezo kwizidlo zabo, ezidlala indima ebalulekileyo kwinkqubo yabo yokuthatha isigqibo malunga nolawulo lwezempilo.

Umbuzo obalulekileyo ngowokuba ingaba kubandakanyeka kwimingcipheko yemfuza kunye noxilongo oluthile lomhlaza xa uthatha isigqibo malunga nokhetho lokutya, olufana neBaicalin. Ngaba umngcipheko wemfuzo womhlaza osuka kutshintsho kwi-TERT uneempembelelo zendlela yebhayoloji efanayo njengotshintsho kwijeni? Ukusuka kwimbono yesondlo, ngaba umngcipheko ohambelana ne-Primary Glioblastoma ulingana ne-Primary Papillary Thyroid Cancer? Ngapha koko, ngaba ukuqwalaselwa kokutya kuhlala kuyafana kwabo baphantsi kwe-Adriamycin njengabo bafumana iTemozolomide? Ezi ngqwalasela zibalulekile ekwenzeni ukhetho lokutya olunolwazi lwabantu abaneengozi ezahlukeneyo zemfuza kunye nonyango lomhlaza.

I-Baicalin-Isongezelelo seSondlo

I-supplement Baicalin iquka uluhlu lwezithako ezisebenzayo, kuquka i-Baicalin, nganye ekhoyo kwiimpawu ezahlukeneyo. Ezi zithako zinefuthe kwiindlela zeemolekyuli, ngokukodwa i-Growth Factor Signaling, i-Oncogenic Cancer Epigenetics kunye ne-Stem Cell Signaling, elawula imiba ebalulekileyo yomhlaza kwinqanaba leeselula, ezifana nokukhula kwethumba, ukusasazeka, kunye nokufa kweeseli. Ukunikezelwa kwale mpembelelo yebhayoloji, ukukhetha izongezo ezifanelekileyo njengeBaicalin, yedwa okanye ngokudibeneyo, iba sisigqibo esibalulekileyo kumxholo wesondlo somhlaza. Xa ucinga ukusebenzisa i-Baicalin kumhlaza, kubalulekile ukuqwalasela ezi zinto zahlukeneyo kunye neendlela. Oku kungenxa yokuba, ngokufanayo nonyango lomhlaza, ukusetyenziswa kwe-Baicalin ayisosigqibo sehlabathi lonke esifanelekileyo kubo bonke abanomhlaza kodwa kufuneka ibe yeyomntu.

Ukukhetha izongezo zeBaicalin

Ukuphendula umbuzo othi 'Ndingayiphepha nini i-Baicalin kwimeko yoMhlaza' ngumngeni kuba impendulo ixhomekeke kumntu ngamnye kakhulu - ngokulula 'Kuxhomekeke!'. Ngokufana nendlela naluphi na unyango lomhlaza olunokuthi lungasebenzi kwisigulane ngasinye, ukubaluleka kunye nokhuseleko okanye iinzuzo ze-Baicalin ziyahluka ngokuxhomekeke kwiimeko zomntu. Izinto ezifana nohlobo oluthile lomhlaza, i-genetic predispositions, unyango lwangoku, ezinye izongezo ezithathwayo, iindlela zokuphila, i-BMI, kunye naluphi na uhlobo oluthile lomzimba, zonke zidlala indima ekunqumeni ukuba i-Baicalin ifanelekile okanye ifanele igwenywe, igxininisa ukubaluleka koqwalaselo lomntu izigqibo ezinjalo.

1. Ngaba i-Baicalin Supplements iya kuxhamla kwi-Primary Papillary Thyroid Cancer izigulane eziphantsi konyango lwe-Adriamycin?

I-Primary Papillary Thyroid Cancer ibonakaliswe ngoguqulo oluthile lwemfuza, i-BRAF, i-NRAS kunye ne-HRAS, ekhokelela kutshintsho kwiindlela ze-biochemical, ngokukodwa i-Oncogenic Cancer Epigenetics, i-RAS-RAF Signaling, i-MAPK Signaling, i-G-protein-coupled Receptor Signaling kunye ne-Growth Factor Signaling. . Ukusebenza konyango lomhlaza, njenge-Adriamycin, kuxhomekeke kwindlela yokusebenza kwezi ndlela zikhethekileyo. Esona sicwangciso sifanelekileyo siquka ukulungelelanisa isenzo sonyango kunye neendlela eziqhuba umhlaza, ngaloo ndlela kuqinisekiswa indlela yobuqu nesebenzayo. Kwiimeko ezinjalo, ukuphepha ukutya okanye izongezo zesondlo ezinokuchasa iziphumo zonyango okanye ukunciphisa olu lungelelwaniso kubalulekile. Ngokomzekelo, isongezelelo se-Baicalin, esichaphazela i-Oncogenic Cancer Epigenetics, ayinakuba lukhetho olufanelekileyo kwimeko ye-Primary Papillary Thyroid Cancer xa i-Adriamycin. Oku kungenxa yokuba isenokuthi iqhubele phambili ngakumbi isifo okanye iphazamise ukusebenza konyango. Xa ukhetha isicwangciso sesondlo, kubalulekile ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluqhubekayo, ubudala, isini, i-BMI, indlela yokuphila, kunye naluphi na utshintsho lwemfuza olwaziwayo.

2. Ngaba i-Baicalin Supplements iya kuxhamla kwiZigulana zeGlioblastoma eziphambili eziphantsi koNyango lweTemozolomide?

I-Glioblastoma eyiprayimari ichongiwe ngokuguqulwa kofuzo oluthile, njenge-TRBV7-7, i-TAS2R46 kunye ne-TP53, ebangela utshintsho kwiindlela ze-biochemical pathways, ngokukodwa i-Growth Factor Signaling, i-Cell Cycle Checkpoints kunye ne-Apoptosis. Ukusebenza kwonyango lomhlaza, njengeTemozolomide, kuchongwa ngokusebenzisana kwayo nezi ndlela. Injongo kukuqinisekisa ukuba unyango luhambelana kakuhle neendlela eziqhuba umhlaza, okwenza kube nendlela yonyango lomntu. Kulo mxholo, ukutya okanye izongezo ezihambelana nonyango okanye ukuphucula oku kulungelelaniswa kufuneka kuthathelwe ingqalelo. Ngokomzekelo, isongezelelo se-Baicalin lukhetho olunengqiqo kulabo abane-Primary Glioblastoma ephantsi kweTemozolomide. Oku kungenxa yokuba i-Baicalin inefuthe kwiindlela ezifana ne-Growth Factor Signaling, enokuthi inqanda izinto eziqhuba i-Primary Glioblastoma okanye izuze ukusebenza kweTemozolomide.

3. Ingaba izongezo ze-Baicalin zikhuselekile kubantu abasempilweni abane-TERT Mutation eManyaniswe neMngcipheko yeGenetic?

I-TERT idlala indima ebalulekileyo kuvavanyo lomngcipheko womhlaza. Utshintsho kwi-TERT lunokuphazamisa iindlela ezibalulekileyo ze-biochemical, ezibandakanya i-Stem Cell Signaling kunye nokulungiswa kwe-DNA, echaphazela ukuphuhliswa komhlaza. Ukuba iphaneli yakho yemfuza ityhila utshintsho kwi-TERT enxulumene noMhlaza we-Hematological, cinga ngokubandakanya izongezo ze-Baicalin kwisicwangciso sakho sesondlo. Ezi zongezo zinokuphembelela ngendlela eyiyo iindlela ezifana neStem Cell Signaling, inzuzo ngokubonelela ngenkxaso efanelekileyo kubantu abanotshintsho lwe-TERT kunye neenkxalabo zempilo ezinxulumeneyo.

Ukuququmbela

Ezona zinto zimbini zibalulekileyo ekufuneka uzikhumbule kukuba unyango lomhlaza kunye nesondlo azinakuze zifane kumntu wonke. Isondlo, kuquka ukutya kunye nezongezelelo ezifana ne-Baicalin, sisixhobo esisebenzayo esinokulawulwa nguwe ngelixa ujongene nomhlaza.

"Ndingatya ntoni?" ngowona mbuzo udla ngokubuzwa ngabaguli abanomhlaza kunye nabo basemngciphekweni womhlaza. Impendulo echanekileyo kukuba ixhomekeke kwizinto ezifana nohlobo lomhlaza, imfuzo yethumba, unyango lwangoku, ukungezwani komzimba, indlela yokuphila, kunye ne-BMI.

Fumana isondlo sakho somhlaza kwi-addon ngokucofa ikhonkco elingezantsi kwaye uphendule imibuzo malunga nohlobo lomhlaza wakho, unyango, indlela yokuphila, i-allergies, ubudala, kunye nesini.

Ucaphulo

• cBioPortal for Cancer Genomics
• I-Baicalin ilawula ukuKhula, i-Apoptosis, ukufuduka, kunye nokuhlasela kwi-Mesothelioma.
• I-Temozolomide ibangela ukuveliswa kwe-epidermal growth factor ukulawula ukubonakaliswa kwe-MDR1 kwiiseli ze-glioblastoma.
• Uhlalutyo lwe-pan-cancer lwe-genomes epheleleyo.
• Ukuthintela i-EMT, i-stemness kunye nomjikelo weeseli ezibandakanyekayo kwi-baicalin-induced growth inhibition kunye ne-apoptosis kwiiseli zomhlaza we-colorectal.
• cBioPortal for Cancer Genomics
• Ukulawulwa kwe-Histone deacetylase ye-ATM-mediated DNA ukubonakaliswa komonakalo.
• Imeko ye-somatic genomic ye-glioblastoma.
• I-Baicalin, i-Chinese Herbal Medicine, inqanda ukuKhuliswa kunye nokufuduka koMntu ongeyena omncinci we-Cell Lung Carcinoma (NSCLC) iiseli, i-A549 kunye ne-H1299, ngokuSebenza i-SIRT1 / i-AMPK ye-Signaling Pathway.