Ngowuphi umhlaza onokuzuza ngokubandakanya iArnica ekutyeni kwabo?

Iimbalasane

I-Arnica iyabonwa ngokubanzi ngenxa yeenzuzo zayo zezempilo kwaye isetyenziswa rhoqo ngabaguli bomhlaza kunye nalabo abasengozini yofuzo. Nangona kunjalo, ukhuseleko kunye nokusebenza kweArnica kwizigulana ezinomhlaza kuxhomekeke kwizinto ezininzi ezinjengomhlaza, ichemotherapy, olunye unyango, kunye nemfuza yethumba. Ukwazi ukuba ezinye ukutya kunye nezongezelelo, ezinje ngegrapefruit kunye nesipinatshi, zinokusebenzisana kakubi namayeza omhlaza kwaye zibangele ukusabela okubi kubalulekile.

Ukutya kubaluleke kakhulu kunyango lomhlaza njengoko kunokuchaphazela iziphumo zonyango. Izigulana ezinomhlaza kufuneka zikhethe ngononophelo kwaye zifake ukutya okufanelekileyo kunye nezongezo kwizidlo zabo. Ngokomzekelo, i-Arnica inokuzuza abo bane-Primary Urachal adenocarcinoma ehamba nge-Gemcitabine, kodwa isenokungabi yinto efanelekileyo kwizigulane ezifumana i-Mitomycin ye-Primary Penile Squamous Cell Carcinoma. Ngapha koko, ngelixa i-Arnica inokunceda abantu abanomngcipheko wemfuza "KRAS", ayinakucetyiswa kwabo banomngcipheko wemfuza eyahlukileyo "ASXL1". Ukwenza izicwangciso zokutya ezisekelwe kwimpilo, unyango, kunye nofuzo kubalulekile.

Ukuqonda ukuba ukwenza isigqibo malunga nokufaneleka kwe-Arnica kwisigulane somhlaza kufuneka ibe ngumntu ngamnye kubalulekile. Izinto ezibalulekileyo ezifana nohlobo lomhlaza, iindlela zonyango, i-genetic makeup, ingozi yemfuza, ubudala, ubunzima bomzimba kunye nendlela yokuphila ibalulekile ekugqibeni ukuba i-Arnica lukhetho olufanelekileyo. I-Genomics kunye ne-genomics, ngokukodwa, yingqwalasela ebalulekileyo. Kuba ezi zinto zinokuvela, kubalulekile ukuphonononga rhoqo kwaye ulungelelanise ukhetho lokutya ukuhambelana notshintsho kwisimo sempilo kunye nonyango.

Ukuqukumbela, indlela epheleleyo ekukhethweni kokutya ibalulekile, igxininise kwimiphumo yonke yazo zonke izinto ezisebenzayo ekutya / izongezo ezifana ne-Arnica endaweni yokuvavanya isithako ngasinye esisebenzayo ngokwahlukileyo okanye ukungayinaki ngokupheleleyo. Lo mbono ubanzi ukhuthaza indlela enengqiqo nenzululwazi yokucwangcisa ukutya komhlaza.

Uluhlu olufutshane

Ukusetyenziswa kokutya okusekelwe kwizityalo kunye nezongezelelo, ezinje ngeevithamini, imifuno, iiminerali, iiprobiotics, kunye nezongezelelo ezahlukeneyo ezikhethekileyo, ziyenyuka phakathi kwabaguli abanomhlaza. Ezi zongezo ziyilelwe ukuhambisa ugxininiso oluphezulu lwezithako ezithile ezisebenzayo, uninzi lwazo zikwakukutya okwahlukeneyo. Ugxininiso kunye nokwahlukana kwezithako ezisebenzayo ziyahluka phakathi kokutya okupheleleyo kunye nezongezelelo. Ukutya ngokuqhelekileyo kunika uluhlu lwezithako ezisebenzayo kodwa kwiindawo ezisezantsi, ngelixa izongezelelo zibonelela ngoxinzelelo oluphezulu lwezithako ezithile.

Ukuthathela ingqalelo imisebenzi eyahlukeneyo yesayensi kunye neyebhayoloji yesithako ngasinye esisebenzayo kwinqanaba leemolekyuli, kubalulekile ukunika ingxelo ngeziphumo ezidityanisiweyo zala malungu xa uthatha isigqibo malunga nokutya kunye nezongezo eziza kutyiwa okanye hayi.

Umbuzo obalulekileyo uvela: Ngaba kufuneka udibanise iArnica kwisidlo sakho njengento yokutya okanye isongezelelo? Ngaba kuyacetyiswa ukuba utye i-Arnica ukuba unemfuza yomhlaza onxulumene nofuzo lwe-KRAS? Kuthekani ukuba endaweni yoko ingozi yakho yemfuza ivela kwi-ASXL1 gene? Ngaba kunenzuzo ukubandakanya iArnica ekutyeni kwakho ukuba ufunyaniswe unePrimary Penile Squamous Cell Carcinoma, okanye ukuba uxilongo lwakho yiPrimary Urachal adenocarcinoma? Ngaphezu koko, ukusetyenziswa kwakho kwe-Arnica kufuneka kuhlengahlengiswe njani ukuba ufumana unyango lwe-Gemcitabine okanye ukuba isicwangciso sakho sonyango siyatshintsha ukusuka kwi-Gemcitabine ukuya kwi-Mitomycin? Kubalulekile ukuqaphela ukuba iziqinisekiso ezilula ezifana 'neArnica yendalo, ngoko ihlala iluncedo' okanye 'iArnica inyusa ukhuselo lomzimba' ayonelanga kukhetho lokutya / lokongezelela.

Ukongeza, kubalulekile ukuvavanya kwakhona ukufaneleka kokubandakanya i-Arnica kwisidlo sakho ukuba kukho utshintsho kwirejimeni yonyango lwakho. Isishwankathelo, xa usenza izigqibo malunga nokubandakanya ukutya okanye izongezo ezifana ne-Arnica kwisondlo sakho ngenxa yezibonelelo zayo, kuya kufuneka uqwalasele iziphumo ze-biochemical yazo zonke izithako, ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluthile olwenzayo, i-genetic predispositions. , kunye nokukhetha indlela yokuphila.

Cancer

Umhlaza usengumceli mngeni obalulekileyo kwicandelo lezonyango, ngokufuthi ubangela unxunguphalo oluxhaphakileyo. Nangona kunjalo, ukuqhubela phambili kwamva nje kuye kwaphucula iziphumo zonyango, ngakumbi ngeendlela zonyango zomntu, iindlela zokujonga ezingaphazamisiyo kusetyenziswa igazi kunye neesampulu zamathe, kunye nophuhliso lwe-immunotherapy. Ukufunyaniswa kwangethuba kunye nokungenelela kwangethuba kuye kwaba yinto ebalulekileyo ekuphembeleleni ngokufanelekileyo iziphumo zonyango ngokubanzi.

Uvavanyo lwemfuzo lunikeza isithembiso esibalulekileyo ekuvavanyeni umngcipheko womhlaza kunye nokuba sesichengeni kwangoko. Nangona kunjalo, kubantu abaninzi abaneemeko zosapho kunye nemfuzo kumhlaza, ukhetho longenelelo lonyango, nokuba lubekwe esweni rhoqo, luhlala lulinganiselwe okanye alukho. Nje ukuba kufunyaniswe ukuba unohlobo oluthile lomhlaza, njengePrimary Urachal adenocarcinoma okanye iPrimary Penile Squamous Cell Carcinoma, izicwangciso zonyango kufuneka zenziwe ngokwezifiso ngokusekwe kwi-tumor genetics yomntu, inqanaba lesi sifo, kunye nezinto ezifana nobudala kunye nesini.

Emva konyango, ukubeka iliso okuqhubekayo kubalulekile ukuze kubonwe naziphi na iimpawu zokubuyela kwakhona komhlaza kunye nokwazisa izigqibo ezilandelayo. Uninzi lwezigulana ezinomhlaza kunye nabo basemngciphekweni bahlala befuna iingcebiso malunga nokubandakanya ukutya okuthile kunye nezongezo kwizidlo zabo, ezidlala indima ebalulekileyo kwinkqubo yabo yokuthatha isigqibo malunga nolawulo lwezempilo.

Umbuzo obalulekileyo ngowokuba ingaba kubandakanyeka kwimingcipheko yemfuza kunye noxilongo oluthile lomhlaza xa uthatha isigqibo malunga nokhetho lokutya, olufana noArnica. Ngaba umngcipheko wemfuza womhlaza ovela kuguquko kwi-KRAS unefuthe elifanayo le-biochemical pathway njengotshintsho kwi-ASXL1? Ukusuka kwimbono yesondlo, ngaba umngcipheko ohambelana ne-Primary Urachal adenocarcinoma ulingana nePrimary Penile Squamous Cell Carcinoma? Ngapha koko, ngaba ukuqwalaselwa kokutya kuhlala kuyafana kwabo bafumana iMitomycin njengakwabo bafumana iGemcitabine? Ezi ngqwalasela zibalulekile ekwenzeni ukhetho lokutya olunolwazi lwabantu abaneengozi ezahlukeneyo zemfuza kunye nonyango lomhlaza.

I-Arnica - Isongezo seSondlo

I-supplement Arnica ibandakanya uluhlu lwezithako ezisebenzayo, kuquka i-Helenalin, nganye ekhoyo kwiimpawu ezihlukeneyo. Ezi zithako zinefuthe kwiindlela zeemolekyuli, ngokukodwa i-Oxidative Stress, i-Cell Cycle, i-DNA Repair kunye ne-TGFB Signaling, elawula imiba ebalulekileyo yomhlaza kwinqanaba leeselula, ezifana nokukhula kwethumba, ukusasazeka, kunye nokufa kweeseli. Ukunikezelwa kwale mpembelelo yebhayoloji, ukukhetha izongezo ezifanelekileyo njengeArnica, yedwa okanye ngokudibeneyo, iba sisigqibo esibalulekileyo kumxholo wesondlo somhlaza. Xa ucinga ukusebenzisa iArnica yomhlaza, kubalulekile ukuqwalasela ezi zinto zahlukeneyo kunye neendlela. Oku kungenxa yokuba, ngokufana nonyango lomhlaza, ukusetyenziswa kwe-Arnica ayisosigqibo sehlabathi lonke esifanelekileyo kuzo zonke ii-cancer kodwa kufuneka zenziwe ngumntu.

Ukukhetha iArnica Supplements

Ukujongana nombuzo othi 'Ndimele ndiphephe nini i-Arnica kumxholo weCancer' ngumngeni kuba impendulo ixhomekeke kakhulu kumntu - ngokulula 'Kuxhomekeke!'. Ngokufana nendlela naluphi na unyango lomhlaza olunokuthi lungasebenzi kwisigulane ngasinye, ukubaluleka kunye nokhuseleko okanye izibonelelo ze-Arnica ziyahluka ngokuxhomekeke kwiimeko zomntu. Izinto ezifana nohlobo oluthile lomhlaza, i-genetic predispositions, unyango lwangoku, ezinye izongezo ezithathwayo, iindlela zokuphila, i-BMI, kunye naluphi na uhlobo oluthile lomzimba, zonke zidlala indima ekunqumeni ukuba i-Arnica ifanelekile okanye ifanele igwenywe, igxininisa ukubaluleka koqwalaselo lomntu izigqibo ezinjalo.

1. Ngaba i-Arnica Supplements iya kuxhamla kwi-Primary Penile Squamous Cell Carcinoma Izigulana eziphantsi konyango lwe-Mitomycin?

I-Primary Penile Squamous Cell Carcinoma ibonakaliswe ngokuguqulwa kofuzo oluthile, oko kukuthi, i-ABRAXAS1, i-PIK3CB kunye ne-NUP93, ekhokelela kwiinguqu kwiindlela ze-biochemical, ngokukodwa i-Cell Cycle, i-Hematopoiesis kunye ne-Inositol Phosphate Signaling. Ukusebenza konyango lomhlaza, njenge-Mitomycin, kuxhomekeke kwindlela yokusebenza kwezi ndlela zikhethekileyo. Esona sicwangciso sifanelekileyo siquka ukulungelelanisa isenzo sonyango kunye neendlela eziqhuba umhlaza, ngaloo ndlela kuqinisekiswa indlela yobuqu nesebenzayo. Kwiimeko ezinjalo, ukuphepha ukutya okanye izongezo zesondlo ezinokuchasa iziphumo zonyango okanye ukunciphisa olu lungelelwaniso kubalulekile. Ngokomzekelo, isongezelelo se-Arnica, esichaphazela i-Cycle Cycle, ayinakuba lukhetho olufanelekileyo kwimeko ye-Primary Penile Squamous Cell Carcinoma xa uqhuba i-Mitomycin. Oku kungenxa yokuba isenokuthi iqhubele phambili ngakumbi isifo okanye iphazamise ukusebenza konyango. Xa ukhetha isicwangciso sesondlo, kubalulekile ukuqwalasela izinto ezifana nohlobo lomhlaza, unyango oluqhubekayo, ubudala, isini, i-BMI, indlela yokuphila, kunye naluphi na utshintsho olwaziwayo lwemfuzo.

2. Ngaba i-Arnica Supplements iya kunceda i-Primary Urachal adenocarcinoma izigulane eziphantsi koNyango lwe-Gemcitabine?

I-Primary Urachal adenocarcinoma ichongiwe ngokuguqulwa kwemfuza ethile, njenge-NFE2L2, TP53 kunye ne-GNAS, ebangela utshintsho kwiindlela ze-biochemical, ngokukodwa i-Oxidative Stress, i-Immune Checkpoints, i-Cell Cycle Checkpoints, i-Apoptosis, i-G-protein-coupled Receptor Signaling kunye ne-Reproductive Hormone Signaling. . Ukusebenza konyango lomhlaza, njenge-Gemcitabine, kugqitywe ngokusebenzisana kwezi ndlela. Injongo kukuqinisekisa ukuba unyango luhambelana kakuhle neendlela eziqhuba umhlaza, okwenza kube nendlela yonyango lomntu. Kulo mxholo, ukutya okanye izongezo ezihambelana nonyango okanye ukuphucula oku kulungelelaniswa kufuneka kuthathelwe ingqalelo. Ngokomzekelo, isongezelelo se-Arnica lukhetho olunengqiqo kulabo abane-Primary Urachal adenocarcinoma ehamba nge-Gemcitabine. Oku kungenxa yokuba i-Arnica inefuthe kwiindlela ezifana ne-Oxidative Stress, enokuthi ithintele izinto eziqhuba i-Primary Urachal adenocarcinoma okanye izuze ukusebenza kweGemcitabine.

3. Ngaba i-Arnica Supplements ikhuselekile kubantu abasempilweni abane-ASXL1 Mutation Associated Genetic Risk?

Iinkampani ezahlukeneyo zibonelela ngeephaneli zemfuza zokuvavanya umngcipheko wemfuza weentlobo ezahlukeneyo zomhlaza. Ezi panels ziquka imizila yemfuza enxulunyaniswa nebele, i-ovarian, i-uterine, i-prostate, kunye nomhlaza wesisu. Ukuvavanya ezi genes kunokuqinisekisa ukuxilongwa kunye nokwazisa unyango kunye nezicwangciso zokulawula. Ukuchonga umahluko obangela isifo kunokuncedisa ngakumbi ekuvavanyeni nasekuxilongweni kwezalamane ezinokuba sengozini. I-ASXL1 gene idla ngokubandakanywa kwezi panels zovavanyo lomngcipheko womhlaza.

Ukuguqulwa kwe-ASXL1 gene kuchaphazela iindlela ze-biochemical okanye iinkqubo, ezifana nokulungiswa kwe-DNA, i-Oncogenic Cancer Epigenetics kunye ne-Suppressive Histone Methylation, ebandakanyeka ngokuthe ngqo okanye ngokungathanga ngqo ekuqhubeni umhlaza kwinqanaba le-molecular. Xa iphaneli yofuzo ichonga ukuguqulwa kwe-ASXL1 ehambelana nomngcipheko okhulayo we-Chronic Myelomonocytic Leukemia, ingqiqo yesayensi icebisa ukuphepha ukusetyenziswa kwe-supplement Arnica. Oku kungenxa yokuba ukongeza i-Arnica inefuthe kwiindlela ezifana nokulungiswa kwe-DNA, enokukhokelela kwimiphumo emibi kumxholo we-ASXL1 yokuguqulwa kunye neemeko zomhlaza ezinxulumene nazo.

4. Ngaba i-Arnica Supplements ikhuselekile kubantu abasempilweni abane-KRAS Mutation eNxulunyaniswe neMngcipheko yeGenetic?

I-KRAS idlala indima ebalulekileyo kuvavanyo lomngcipheko womhlaza. Ukuguqulwa kwe-KRAS kunokuphazamisa iindlela ezibalulekileyo ze-biochemical, ezibandakanya i-TGFB Signaling, i-MAPK Signaling, i-PI3K-AKT-MTOR Umqondiso kunye ne-RAS-RAF Signaling, echaphazela ukuphuhliswa komhlaza. Ukuba iphaneli yakho yemfuza ityhila utshintsho kwi-KRAS ehambelana noMhlaza weLung, cinga ngokubandakanya izongezo zeArnica kwisicwangciso sakho sesondlo. Ezi zongezo zinokuphembelela ngendlela eyiyo iindlela ezifana ne-TGFB Umqondiso, inzuzo ngokubonelela ngenkxaso efanelekileyo kubantu abaneenguqu ze-KRAS kunye neenkxalabo zempilo ezinxulumeneyo.

Ukuququmbela

Ezona zinto zimbini zibalulekileyo ekufuneka uzikhumbule kukuba unyango lomhlaza kunye nesondlo azinakuze zifane kumntu wonke. Isondlo, kubandakanya ukutya kunye nezongezelelo ezifana neArnica, sisixhobo esisebenzayo esinokulawulwa nguwe ngelixa ujongene nomhlaza.

"Ndingatya ntoni?" ngowona mbuzo udla ngokubuzwa ngabaguli abanomhlaza kunye nabo basemngciphekweni womhlaza. Impendulo echanekileyo kukuba ixhomekeke kwizinto ezifana nohlobo lomhlaza, imfuzo yethumba, unyango lwangoku, ukungezwani komzimba, indlela yokuphila, kunye ne-BMI.

Fumana isondlo sakho somhlaza kwi-addon ngokucofa ikhonkco elingezantsi kwaye uphendule imibuzo malunga nohlobo lomhlaza wakho, unyango, indlela yokuphila, i-allergies, ubudala, kunye nesini.

Ucaphulo

• Iiseti ezichazwe ngokwemfuza zomhlaza wepancreatic womntu zibonisa eyodwa kwi-vitro chemosensitivity.
• cBioPortal for Cancer Genomics
• Unyango lomhlaza lubumba ubume bokuqina be-clonal hematopoiesis.
• Iindlela zokoyisa ukuchasana kwe-Intrinsic kwi-Gemcitabine kwi-Pancreatic Ductal Adenocarcinoma ngokusebenzisa i-Redox Modulation.
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.