Ukutya kwe-Infantile Sarcoma!

intshayelelo

Ukutya kwe-Infantile Sarcoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Kwi-Infantile Sarcoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Infantile Sarcoma ingaba ibalulekile into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwizityalo ngaba kwanele umhlaza onje nge-Infantile Sarcoma?

Umzekelo ingaba ibalulekile into yokuba imifuno yeCelery Stalks ityiwa kakhulu xa ithelekiswa neCarob? Ngaba kuyawenza umahluko ukuba isiqhamo seGrapefruit siyakhethwa kuneSoursop? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neChestnut phezu kweHickory Nut kunye neepulses ezifana ne-Black-eyed Pea phezu kweSoy Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Infantile Sarcoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Infantile Sarcoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo iGrapefruit iqulethe izithako ezisebenzayo iLuteolin, iLupeol, iGeraniol, iDaidzein, i-Eugenol. Kwaye i-Soursop iqulethe izithako ezisebenzayo i-Fisetin, i-Apigenin, i-Luteolin, i-Lupeol, i-Geraniol kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo nokukhetha ukutya okuza kutyiwa kwi-Infantile Sarcoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungahoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Infantile Sarcoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Infantile Sarcoma?

Isondlo somntu somhlaza onje nge-Infantile Sarcoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji ye-Infantile Sarcoma, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Infantile Sarcoma

Zonke ii-cancer ezifana ne-Infantile Sarcoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Infantile Sarcoma. Iindlela ze-Biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, ii-Checkpoints ze-Cell Cycle, i-MAPK Ukubonakaliswa yinxalenye yenkcazo yesignesha ye-Infantile Sarcoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Infantile Sarcoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Infantile Sarcoma xa uthatha unyango lomhlaza ngeRadiation, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-ACVR1, i-CDKN2A, i-MAP3K13 kunye ne-NTRK3 zezona ntlobo zemfuza ezixeliweyo eziphezulu ze-Infantile Sarcoma. I-ACVR1 ixelwe kwi-100.0 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-CDKN2A ichazwe kwi-100.0%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-50.0% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji ye-Infantile Sarcoma kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenza isondlo somntu.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Infantile Sarcoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CELERY STLKS okanye iCAROB?

Imifuno ye-Celery Stalks iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Luteolin, i-Lupeol, i-Caffeine, i-Geraniol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. I-Celery Stalks iyacetyiswa kwi-Infantile Sarcoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba iCelery Stalks ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhanyise isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeCarob yi-Apigenin, i-Luteolin, i-Lupeol, i-Quercetin, i-Geraniol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. I-Carob ayikhuthazwa kwi-Infantile Sarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

IZIDLA ZEMIFUNO YECEREY IYAKUNIKEZISWA NGAPHEZU KWE-CAROB KWI-Infantile Sarcoma KUNYE NONYANGO LWERadiation.

Khetha iSiqhamo SOURSOP okanye GRAPEFRUIT?

I-Fruit Soursop iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Fisetin, i-Apigenin, i-Luteolin, i-Lupeol, i-Geraniol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. I-Soursop iyacetyiswa kwi-Infantile Sarcoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba i-Soursop ilungisa ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yiLuteolin, iLupeol, iGeraniol, iDaidzein, i-Eugenol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. IGrapefruit ayikhuthazwa kwi-Infantile Sarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO SOURSOP IYANCEBISWA NGAPHEZU KWEGRAPEFRUIT KWI-Infantile Sarcoma KUNYE NONYANGO LWERadiation.

Khetha Nut CHESTNUT okanye HICKORY NUT?

I-Chestnut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Luteolin, i-Lupeol, i-Ellagic Acid, i-Caffeine. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. I-Chestnut iyacetyiswa kwi-Infantile Sarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation. Oku kungenxa yokuba i-Chestnut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Hickory Nut yi-Apigenin, i-Luteolin, i-Lupeol, i-Caffeine, i-Geraniol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayoloji ezifana noMjikelo weSeli kunye nezinye. I-Hickory Nut ayikhuthazwa kwi-Infantile Sarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli ngokukhawuleza.

I-CHESTNUT INCEBISWA NGAPHEZU KWE-HICKORY NUT YE-Infantile Sarcoma KUNYE NONYANGO LWERadiation.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Infantile Sarcoma okanye imbali yosapho "Yintoni ekufuneka Ndiyitye Ngokwahlukileyo Kwangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD CARROT okanye WELSH anyanisi?

I-Vegetable Wild Carrot iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Vitamin E. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Apoptosis, i-Cell Cycle kunye ne-P53 Signaling kunye nabanye. I-Wild Carrot icetyiswa kumngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo ohambelana ne-ACVR1. Oku kungenxa yokuba i-Wild Carrot yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Welsh Onion yi-Curcumin, i-Lupeol, i-Daidzein, i-Lycopene, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye neCell Cycle Checkpoints kunye nezinye. Itswele le-Welsh alikhuthazwa xa umngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo uhambelana ne-ACVR1 kuba yonyusa iindlela zokutyikitya.

UMNQATHA WASEMHLANGA WOMFUNO UYCEBISWA NGAPHEZU KWE-WELSH ITswele NGE-ACVR1 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo JAVA PLUM okanye iPUMMELO?

Iziqhamo zeJava Plum ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, i-MAPK Signaling, i-Cell Cycle kunye ne-P53 yokuSayina kunye nabanye. IJava Plum iyacetyiswa kumngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo ohambelana ne-ACVR1. Oku kungenxa yokuba iJava Plum yonyusa ezo ndlela zebhayokhemikhali ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Quercetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye neCell Cycle Checkpoints kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo uhambelana ne-ACVR1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO JAVA PLUM IYANCEBISWA NGAPHEZU KWE-PUMMELO NGE-ACVR1 GENETIC RISK YOMHLAZA.

Khetha i-Nutt EQHELEKILEYO IHAZELNUT okanye i-EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Daidzein, i-Quercetin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, i-MAPK Signaling, i-Cell Cycle kunye ne-P53 yokuSayina kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo ohambelana ne-ACVR1. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Infantile Sarcoma xa umngcipheko wemfuzo uhambelana ne-ACVR1 kuba yonyusa iindlela zokutyikitya.

IHAZELNUT EQHELEKILEYO IYAKUNIKEZWA NGE-CHESTNUT YAseYurophu NGE-ACVR1 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Infantile Sarcoma. Izigulana ze-Infantile Sarcoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Infantile Sarcoma, nganye inemfuza eyahlukileyo ye-tumor enolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunje ngeCelery Stalks kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Infantile Sarcoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Sarcoma Mskcc 2022
• I-Vitamin C iphucula ukuguqulwa kwe-epigenetic eyenziwa yi-5-azacytidine kunye nokubanjwa komjikelo weseli kwi-hepatocellular carcinoma celllines HLE kunye ne-Huh7.
• I-asidi ye-Shikimic ikhuthaza i-estrogen receptor (ER) -iiseli zomhlaza webele ezintle zikhula ngokusebenza kwe-NF-κB yokubonisa.
• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.
• I-Eugenol ibangela i-apoptosis kwiiseli zomhlaza wamabele ngokusebenzisa i-E2F1/survivin down-regulation.
• I-Geraniol, icandelo lee-oyile ezibalulekileyo zesityalo, ikhuthaza iiseli zomhlaza wekholoni yomntu kwi-5-Fluorouracil unyango.