Ukutya kweGastrointestinal Neuroendocrine Tumors!

intshayelelo

Ukutya kweGastrointestinal Neuroendocrine Amathumba kufuneka enzelwe umntu ngamnye kwaye kufuneka alungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KwiGastrointestinal Neuroendocrine Tumors ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza womhlaza onje ngeGastrointestinal Neuroendocrine Tumors ingaba ayinamsebenzi into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekelwe kwisityalo oko kwanele umhlaza njengeGastrointestinal Neuroendocrine Tumors?

Umzekelo ingaba inomsebenzi ukuba imifuno yePotato ityiwa kakhulu xa ithelekiswa neCardoon? Ngaba kwenza umahluko ukuba isiqhamo saseAsia Pear sikhethwa ngaphezu kweMandarin Orange (clementine, Tangerine)? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neWalnut phezu kweChestnut kunye neepulses ezifana neHyacinth Bean phezu kweCommon Bean. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Gastrointestinal Neuroendocrine Tumors kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo imiba yeGastrointestinal Neuroendocrine Tumors!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo i-Asian Pear iqulethe izithako ezisebenzayo iProtocatechuic Acid, Lupeol, Apigenin, Curcumin, Daidzein. Kwaye i-Mandarin Orange (i-clementine, i-Tangerine) iqulethe izithako ezisebenzayo i-Linalool, i-Protocatechuic Acid, i-Lupeol, i-Curcumin, i-Daidzein kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Gastrointestinal Neuroendocrine Tumors - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi yonke into. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seGastrointestinal Neuroendocrine Tumors.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiGastrointestinal Neuroendocrine Tumors?

Izondlo zomntu zomhlaza ezifana neGastrointestinal Neuroendocrine Tumors ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Gastrointestinal Neuroendocrine Tumors biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neGastrointestinal Neuroendocrine Tumors

Zonke ii-cancer ezifana ne-Gastrointestinal Neuroendocrine Tumors zinokubonakaliswa ngeseti ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya zeGastrointestinal Neuroendocrine Tumors. Iindlela ze-Biochemical ezifana ne-Apoptosis, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Oncogenic Histone Methylation, i-Oxidative Stress iyingxenye yenkcazo yesignesha ye-Gastrointestinal Neuroendocrine Tumors. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiGastrointestinal Neuroendocrine Tumors kufuneka ithathelwe ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwiGastrointestinal Neuroendocrine Tumors xa uthatha unyango lomhlaza iTrabectionin, kwaye ezinye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-ALK, i-APC, i-DAXX, i-GNAS kunye ne-KMT2D ziintlobo eziphezulu ezichazwe kwi-Gastrointestinal Neuroendocrine Tumors. I-ALK ixelwe kwi-16.7% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-APC ixelwe kwi-16.7%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-55.0% yedatha yesigulane ichongwa njengamadoda. IGastrointestinal Neuroendocrine Tumors biology kunye ne genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zeGastrointestinal Neuroendocrine Tumors

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iPATATO yemifuno okanye iCARDOON?

I-Potato yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neProtocatechuic Acid, Lupeol, Curcumin, Daidzein, Cinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis kunye ne-PI3K-AKT-MTOR Ukubonisana kunye nabanye. Iitapile iyacetyiswa kwiGastrointestinal Neuroendocrine Tumors xa unyango oluqhubekayo lomhlaza luyiTrabectedin. Oku kungenxa yokuba i-Potato iguqula ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Trabectedin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeCardoon yi-Lycopene, i-Protocatechuic Acid, i-Lupeol, i-Apigenin, i-Curcumin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Cardoon ayikhuthazwa kwiGastrointestinal Neuroendocrine Tumors xa unyango lomhlaza oluqhubekayo luyiTrabectin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-PATATO YOMFUNO INCEBISWA NGAPHEZU KWE-CARDOON YE-Gastrointestinal Neuroendocrine Tumors KUNYE NONYANGO I-Trabectedin.

Khetha iSiqhamo se-MANDARIN ORANGE (CLEMENTINE, TANGERINE) okanye i-ASIAN PEAR?

Isiqhamo seMandarin Orange (i-clementine, i-Tangerine) iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Linalool, i-Protocatechuic Acid, i-Lupeol, i-Curcumin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-MYC Signaling kunye ne-PI3K-AKT-MTOR Ukubonisana kunye nabanye. I-Mandarin Orange (i-clementine, i-Tangerine) icetyiswa kwi-Gastrointestinal Neuroendocrine Tumors xa unyango oluqhubekayo lomhlaza we-Trabectedin. Oku kungenxa yokuba i-Mandarin Orange (i-clementine, i-Tangerine) iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Trabectedin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zaseAsia Pear yiProtocatechuic Acid, Lupeol, Apigenin, Curcumin, Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Asian Pear ayikhuthazwa kwiGastrointestinal Neuroendocrine Tumors xa unyango lomhlaza oluqhubekayo luyiTrabectin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO I-MANDARIN ORANGE (CLEMENTINE, TANGERINE) KUNCEBISWA NGAPHEZU KWE-ASIAN PEAR YE-Gastrointestinal Neuroendocrine Tumors KUNYE NONYANGO I-Trabectedin.

Khetha i-Nut WALNUT okanye i-CHESTNUT?

I-Walnut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-D-limonene, i-Protocatechuic Acid, i-Lupeol, i-Curcumin, i-Apigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis kunye ne-PI3K-AKT-MTOR Ukubonisana kunye nabanye. IWalnut icetyiswa kwiGastrointestinal Neuroendocrine Tumors xa unyango oluqhubekayo lomhlaza luyiTrabectedin. Oku kungenxa yokuba i-Walnut iguqula ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Trabectedin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Lycopene, i-Protocatechuic Acid, i-Lupeol, i-Apigenin, i-Curcumin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut ayikhuthazwa kwiGastrointestinal Neuroendocrine Tumors xa unyango lomhlaza oluqhubekayo iTrabectedin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-WALNUT INCEBISWA NGAPHEZU KWE-CHESTNUT YE-Gastrointestinal Neuroendocrine Tumors KUNYE NONYANGO I-Trabectedin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Gastrointestinal Neuroendocrine Tumors okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or KOHLRABI?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Isoliquiritigenin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF yokuSayina, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wemfuzo ohambelana ne-ALK. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Kohlrabi yi-Quercetin, i-Curcumin, i-Formononetin, i-Isoliquiritigenin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-WNT Beta Catenin Signaling, iStem Cell Signaling kunye ne-MYC Signaling kunye nabanye. I-Kohlrabi ayikhuthazwa xa umngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wezofuzo uhambelana ne-ALK kuba inyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINQIZI YOMFUNO KUNCEBISWA PHEZU KWE-KOHLRABI NGE-ALK GENETIC RISK YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Isoliquiritigenin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF yokuSayina, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Nance icetyiswa kumngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wemfuzo ohambelana ne-ALK. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Quercetin, i-Curcumin, i-Apigenin, i-Formononetin, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayochemicals ezifana neCell Cycle Checkpoints kunye neWNT Beta Catenin Signaling kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wemfuzo uhambelana ne-ALK kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO NGE-ALK GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Isoliquiritigenin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-RAS-RAF Signaling, i-MYC Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Butternut iyacetyiswa kumngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wemfuzo ohambelana ne-ALK. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Curcumin, i-Apigenin, i-Ellagic Acid, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko weGastrointestinal Neuroendocrine Tumors xa umngcipheko wezofuzo uhambelana ne-ALK kuba yonyusa iindlela zokutyikitya.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT NGE-ALK genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neGastrointestinal Neuroendocrine Tumors. I-Gastrointestinal Neuroendocrine Izigulana kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana neGastrointestinal Neuroendocrine Tumors, nganye inee-tumor genetics ezahlukeneyo ezinolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana nePotato kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwiGastrointestinal Neuroendocrine Tumors?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• UFikelelo lweMsk 2021
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