Ukutya kweFibrosarcoma!

intshayelelo

Ukutya kwe-Fibrosarcoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Fibrosarcoma luhlobo lomhlaza olusuka kwiifibrous tissues zomzimba. Inokwenzeka kwiindawo ezahlukeneyo, kubandakanya unyawo, umphambili kunye nomnwe. Ikhowudi yezonyango echanekileyo kusetyenziswa ikhowudi ye-ICD-10 efanelekileyo ibalulekile ekubhalweni. Ulwandlalo lwePathology lubonelela ngolwazi oluxabisekileyo kwiimpawu zeeseli ze-fibrosarcoma. I-Radiology inceda ekuxilongweni nasekuvavanyeni i-fibrosarcoma, inceda ekucwangciseni unyango. Iinketho zonyango lwe-fibrosarcoma zinokubandakanya utyando, ichemotherapy, okanye unyango lweradiation, kuxhomekeke kwindawo kunye nenqanaba lethumba. Amazinga okusinda kwi-fibrosarcoma anokwahluka ngokuxhomekeke kwizinto ezizimeleyo, ezifana nobungakanani besifo kunye nokuphendula kunyango. Ukuxilongwa kwangoko kunye nonyango olukhawulezileyo lubalulekile kwiziphumo eziphuculweyo. Ukuqaphela iimpawu kunye nemingcipheko ehambelana ne-fibrosarcoma inokunceda ekubonweni kwangaphambili kunye nokungenelela. I-Fibrosarcoma inokuchaphazela izinja, kwaye ukuxilongwa kunye nenkqubo yonyango inokwahluka. Ngokufuna unyango olufanelekileyo kunye nokujonga iindlela zonyango ezikhoyo, abantu abane-fibrosarcoma banokuwongeza amathuba abo esiphumo esiyimpumelelo.

KwiFibrosarcoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa ngabaguli abanomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neFibrosarcoma ingaba ibalulekile na into yokutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngeFibrosarcoma?

Umzekelo ingaba inomsebenzi ukuba iCauliflower yemifuno ityiwa kakhulu xa ithelekiswa noMnquma? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyakhethwa kuneSoursop? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neWalnut eqhelekileyo ngaphezu kweChestnut yaseYurophu kunye nezityalo ezifana neGram Bean phezu kweLima Bean. Kwaye ukuba into endiyityayo ibalulekile-ke umntu ukuchonga njani ukutya okucetyiswayo kwi-Fibrosarcoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiFibrosarcoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo Apigenin, Curcumin, Lycopene, Quercetin, Phloretin. Kwaye i-Soursop iqulethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Emodin, i-Fisetin, i-Phloretin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Fibrosarcoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungazihoyi ezinye. Kuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seFibrosarcoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiFibrosarcoma?

Izondlo zomntu zomhlaza ezifana neFibrosarcoma zibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yeFibrosarcoma, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neFibrosarcoma

Zonke ii-cancer ezifana ne-Fibrosarcoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Fibrosarcoma. Iindlela ze-Biochemical ezifana ne-Apoptosis, i-Cell Cycle, i-MAPK Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa yinxalenye yenkcazo yesiginesha ye-Fibrosarcoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Fibrosarcoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Fibrosarcoma xa uthatha unyango lomhlaza i-Eribulin, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-ATRX, i-PREX2, i-CYP17A1 kunye ne-BRAF zezona ziphezulu iigenes ezixeliweyo ze-Fibrosarcoma. I-TP53 ixelwe kwi-23.5% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-ATRX ixelwe kwi-23.5%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-53.7% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeFibrosarcoma kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeFibrosarcoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CAULIFLOWER okanye UMNTU?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Phloretin, i-Daidzein, i-Beta-sitosterol, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Cauliflower iyacetyiswa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin. Oku kungenxa yokuba i-Cauliflower iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zenze impembelelo ye-Eribulin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Olive yi-Curcumin, i-Quercetin, i-Phloretin, i-Hydroxytyrosol, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis kunye ne-PI3K-AKT-MTOR Ukubonisana kunye nabanye. Umnquma awunconywa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CAULIFLOWER YOMFUNO INCEBISWA NGAPHEZU KOMNQUMO NGE-Fibrosarcoma KUNYE NE-Eribulin YONYANGO.

Khetha iSiqhamo SOURSOP okanye iPUMMELO?

I-Fruit Soursop iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Emodin, i-Fisetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-Cell Cycle kunye ne-MAPK Signaling kunye nezinye. I-Soursop iyacetyiswa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin. Oku kungenxa yokuba i-Soursop iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Eribulin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Apigenin, i-Curcumin, i-Lycopene, i-Quercetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. IPummelo ayikhuthazwa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO SOURSOP KUNCEBISWA NGAPHEZU KWE-PUMMELO YE-Fibrosarcoma KUNYE NONYANGO Eribulin.

Khetha Nut WALNUT EQHELEKILEYO okanye i-EUROPEAN CHESTNUT?

I-Walnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Apoptosis kunye nabanye. I-Walnut eqhelekileyo icetyiswa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin. Oku kungenxa yokuba i-Walnut eqhelekileyo iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Eribulin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Ellagic Acid, i-Apigenin, i-Curcumin, i-Quercetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Fibrosarcoma xa unyango lomhlaza oluqhubekayo yi-Eribulin kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IWALNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWE-EUROPE-CHESTNUT YE-Fibrosarcoma KUNYE NONYANGO i-Eribulin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Fibrosarcoma okanye imbali yosapho "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or MUSTARD SPINACH?

I-Vegetable Giant Butterbur iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-RAS-RAF Signaling, i-Reproductive Hormone Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Butterbur enkulu iyacetyiswa kumngcipheko we-Fibrosarcoma xa umngcipheko wemfuzo ohambelana ne-ATRX. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Mustard Spinach yi-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints kunye ne-Oncogenic Cancer Epigenetics kunye nezinye. I-Mustard Spinach ayikhuthazwa xa umngcipheko we-Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yonyusa iindlela zokutyikitya.

IBHUTTERBURE EYISINQIZI YOMFUNO IYACEBISWA NGAPHEZU KWEMUSTARD SPINACH NGE-ATRX genetic RISK OF CANCER.

Khetha iFruit RED RASPBERRY okanye iGUAVA?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuSayina kwe-MAPK, ii-Checkpoints ze-Cell Cycle, i-RAS-RAF Signaling kunye ne-TGFB Signaling kunye nabanye. I-Raspberry ebomvu inconywa kumngcipheko we-Fibrosarcoma xa ingozi yemfuza ehambelana nayo i-ATRX. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGuava yi-Ellagic Acid, i-Apigenin, i-Curcumin, i-Quercetin, i-Linalool. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Guava ayikhuthazwa xa umngcipheko we-Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yongeza iindlela zokutyikitya.

ISIQHAMO ERED RASPBERRY KUNCEBISWA PHEZU KWE-GUAVA YE-ATRX GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lycopene, i-Myricetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuSayina kwe-MAPK, ii-Checkpoints ze-Cell Cycle, i-RAS-RAF Signaling kunye ne-TGFB Signaling kunye nabanye. I-Hazelnut eqhelekileyo icetyiswa kumngcipheko we-Fibrosarcoma xa umngcipheko wemfuza ohambelana ne-ATRX. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Ellagic Acid, i-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yonyusa iindlela zokutyikitya.

I-HAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-CHESTNUT YE-ATRX GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neFibrosarcoma. Izigulana ze-Fibrosarcoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Fibrosarcoma, nganye inemfuza eyahlukileyo ye-tumor enolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neCauliflower kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon yesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Fibrosarcoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Pelargonidin yenza imiphumo ye-antitumor kwiiseli ze-osteosarcoma zomntu ngokusebenzisa i-autophagy induction, ukulahlekelwa kwe-membrane ye-mitochondrial, ukubanjwa kwe-cell cycle ye-G2 / M kunye nokunciphisa indlela yokubonisa i-PI3K / AKT.
• I-Brassinin icinezela amandla okuHlabaza okuHlangeneyo kweeSeli ze-Lung Carcinoma ngoKucinywa kwe-PI3K/Akt/mTOR I-Signaling Cascade.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.
• https://www.ncbi.nlm.nih.gov/books/NBK560759
• https://my.clevelandclinic.org/health/diseases/22009-fibrosarcoma