Ukutya kwi-Erdheim Chester Disease!

intshayelelo

Ukutya kweSifo se-Erdheim Chester kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Erdheim-Chester Disease (ECD) sisifo esinqabileyo, esingeyo-Langerhans cell histiocytosis, esihlala sithathwa njengomhlaza, nonobangela waso uphantsi kophando kodwa awujongwa njengelifa okanye ufuzo. Iphawulwa ngeempawu ezahlukileyo ezifana neentlungu zethambo kunye nokubonakaliswa kwemithambo-luvo, ukuxilongwa kwe-ECD kubandakanya umxube weendlela zotshiso lwemitha, kuquka i-CT kunye ne-MRI yobuchopho, kunye noludwe lwe-pathology olucokisekileyo. Izicwangciso zonyango ze-Erdheim-Chester Disease zihlala zivela, kunye nolwazi oluhlaziyiweyo olufikeleleke ngamaqonga afana ne-UpToDate kunye ne-Erdheim-Chester Disease Global Alliance. I-ECD ihlala ibandakanya izixokelelwano zamalungu afana nemiphunga nengqondo, kwaye iradiology ibalulekile kuvavanyo lwesifo kunye nokubeka iliso. Ihlelwe phantsi kwenkqubo ye-ICD-10, ulawulo lwe-ECD lukhanyiswa ngokuphononongwa kunye nezifundo zamatyala, zigxininisa ukubaluleka kophando oluqhubekayo kunye nokuqonda ekujonganeni nesi sifo esinzima.

KwiSifo se-Erdheim Chester ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje nge-Erdheim Chester Disease ingaba iyabaluleka na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekelwe kwisityalo oko kwanele umhlaza onjenge-Erdheim Chester Disease?

Umzekelo ingaba inomsebenzi ukuba imifuno ye-Eggplant ityiwa kakhulu xa ithelekiswa neChayote? Ngaba kuyawenza umahluko ukuba iziqhamo ze-Sugar Apple zikhethwa ngaphezu kwe-Arctic Blackberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neWalnut emnyama phezu kwe-Macadamia Nut kunye nezityalo ezifana ne-Green Bean phezu kwe-Catjang Pea. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwiSifo se-Erdheim Chester kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kunemicimbi ye-Erdheim Chester Disease!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo i-Sugar Apple iqulethe izithako ezisebenzayo iMyricetin, iLycopene, iPelargonidin, iCurcumin, iCinnamaldehyde. Kwaye iArctic Blackberry iqulethe izithako ezisebenzayo iEllagic Acid, iLycopene, iCurcumin, iQuercetin, iCinnamaldehyde kunye nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Erdheim Chester Disease - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Erdheim Chester Disease.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiSifo se-Erdheim Chester?

Izondlo zomntu zomhlaza ezifana ne-Erdheim Chester Disease ziquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yeSifo i-Erdheim Chester, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Erdheim Chester Disease

Zonke ii-cancer ezifana ne-Erdheim Chester Disease zingabonakaliswa ngesethi ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Erdheim Chester Disease. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-MAPK Signaling, i-Cytoskeletal Dynamics, i-Angiogenesis iyingxenye yenkcazo yesignesha ye-Erdheim Chester Disease. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiSifo i-Erdheim Chester kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiSifo i-Erdheim Chester xa uthatha unyango lomhlaza iVemurafenib, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MAP2K1, i-ARAF, i-ARID5B, i-BRAF kunye ne-MYCN zezona ntlobo zemfuza zibekwe phezulu kwi-Erdheim Chester Disease. I-MAP2K1 ixelwe kwi-25.0 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-ARAF ixelwe kwi-12.5%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-61.5% yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeSifo se-Erdheim Chester kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Erdheim Chester Disease

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable EGGPLANT okanye iCHAYOTE?

I-Eggplant yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Myricetin, i-Isorhamnetin, i-Gallic Acid, i-Curcumin, i-Quercetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-RAS-RAF yokuSayina kunye ne-MAPK yokuSayina kunye nabanye. Isitshalo seqanda siyacetyiswa kwi-Erdheim Chester Disease xa unyango lomhlaza oluqhubekayo luyiVemurafenib. Oku kungenxa yokuba i-Eggplant iguqula iindlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seVemurafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chayote yemifuno yi-Myricetin, i-Pelargonidin, i-Curcumin, i-Cinnamaldehyde, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye ne-MAPK Signaling kunye nezinye. I-Chayote ayikhuthazwa kwiSifo i-Erdheim Chester xa unyango lomhlaza oluqhubekayo yi-Vemurafenib kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-EGGPLANT YOMFUNO INCEBISIWE NGAPHEZU KWE-CHAYOTE NGESIFO I-Erdheim Chester KUNYE NONYANGO I-Vemurafenib.

Khetha iSiqhamo i-ARCTIC BLACKBERRY okanye i-APPLE YESWUKA?

Iziqhamo zeArctic Blackberry ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Lycopene, i-Curcumin, i-Quercetin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-RAS-RAF yokuSayina kunye ne-MAPK yokuSayina kunye nabanye. I-Arctic Blackberry iyacetyiswa kwi-Erdheim Chester Disease xa unyango lomhlaza oluqhubekayo yiVemurafenib. Oku kungenxa yokuba iArctic Blackberry ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukwazisa isiphumo seVemurafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo ze-Sugar Apple yi-Myricetin, i-Lycopene, i-Pelargonidin, i-Curcumin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebiochemical ezifana neWNT Beta Catenin Signaling kunye nezinye. I-apile yeswekile ayikhuthazwa kwiSifo i-Erdheim Chester xa unyango lomhlaza oluqhubekayo yiVemurafenib kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO I-ARCTIC BLACKBERRY IYACEBISWA NGAPHEZU KWE-Apile YESWEKILE NGESIFO E-Erdheim Chester KUNYE NONYANGO I-Vemurafenib.

Khetha Nut BLACK WALNUT okanye MACADAMIA NUT?

I-Walnut emnyama iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Myricetin, i-Ellagic Acid, i-Pelargonidin, i-Gallic Acid, i-Curcumin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF yokuSayina kunye ne-MAPK yokuSayina kunye nabanye. IWalnut emnyama icetyiswa kwiSifo i-Erdheim Chester xa unyango lomhlaza oluqhubekayo yiVemurafenib. Oku kungenxa yokuba iWalnut emnyama ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seVemurafenib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Macadamia Nut yiMyricetin, Pelargonidin, Curcumin, Cinnamaldehyde, Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye ne-MAPK Signaling kunye nezinye. I-Macadamia Nut ayikhuthazwa kwiSifo i-Erdheim Chester xa unyango lomhlaza oluqhubekayo yiVemurafenib kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IWALNUT EMNYAMA KUCEBISWA NGAPHEZU KWE-MACADAMIA NUT NGESIFO I-Erdheim Chester KUNYE NONYANGO IVemurafenib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Erdheim Chester Disease okanye imbali yentsapho "Yintoni endimele ndiyitye ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or GARLAND CHRYSANTHEMUM?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, i-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Erdheim Chester Disease xa umngcipheko wemfuzo ohambelana ne-ARAF. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Garland Chrysanthemum yi-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye ne-MAPK Signaling kunye nezinye. I-Garland Chrysanthemum ayikhuthazwa xa umngcipheko we-Erdheim Chester Disease xa umngcipheko wezofuzo uhambelana ne-ARAF kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINQIZI YOMFUNO IYACEBISWA PHEZU KWEGARLAND CHRYSANTHEMUM NGEMNGCIPHEKO YOMHLAZA YE-ARAF.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Myricetin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, i-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Nance icetyiswa kumngcipheko we-Erdheim Chester Disease xa umngcipheko wemfuzo ohambelana ne-ARAF. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Lycopene, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye neCell Cycle Checkpoints kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Erdheim Chester Disease xa umngcipheko wezofuzo uhambelana ne-ARAF kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO NGE-ARAF genetic RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, i-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko we-Erdheim Chester Disease xa umngcipheko wemfuzo ohambelana ne-ARAF. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Ellagic Acid, i-Curcumin, i-Quercetin, i-Myricetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling, i-PI3K-AKT-MTOR Umqondiso kunye ne-MYC Signaling kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Erdheim Chester Disease xa umngcipheko wezofuzo uhambelana ne-ARAF kuba yonyusa iindlela zokutyikitya kuyo.

IHAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-EUROPE-CHESTNUT NGE-ARAF genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Erdheim Chester Disease. Izigulana ze-Erdheim Chester kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana neSifo i-Erdheim Chester, nganye ineemfuza ezahlukeneyo zethumba ezinolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Eggplant kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Erdheim Chester Disease?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Retinol inciphisa amanqanaba eprotheyini ye-beta-catenin kwimigca yeseli ye-retinoic acid-resistant colon cancer.
• I-Geraniol, icandelo lee-oyile ezibalulekileyo zesityalo, ikhuthaza iiseli zomhlaza wekholoni yomntu kwi-5-Fluorouracil unyango.
• I-Chemoprevention of intestinal tumorigenesis yindalo yokutya i-flavonoid myricetin kwi-APCMin/+ iimpuku.
• Ukhuseleko oluchasene nempembelelo yentengiso yeti emhlophe kunye necaffeine kwi-PhIP-induced tumorigenesis kunye ne-beta-catenin expression kwi-rat.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• https://medlineplus.gov/genetics/condition/erdheim-chester-disease/#resources
• https://rarediseases.org/rare-diseases/erdheim-chester-disease
• https://histio.org/histiocytic-disorders/erdheim-chester-disease
• https://www.lls.org/sites/default/files/2022-07/FS37_Erdheim_Chester_2022.pdf