Ukutya kweColorectal Adenocarcinoma!

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Ukutya kweColorectal Adenocarcinoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Colorectal adenocarcinoma luhlobo lomhlaza oqala kwiiseli ezijikeleze ikholoni okanye i-rectum. Ukuqaphela iimpawu ze-colorectal adenocarcinoma kubalulekile ekubhaqweni kwangaphambili kwaye kubandakanya utshintsho kwimikhwa yamathumbu, igazi kwi-stool, intlungu yesisu, kunye nokulahlekelwa kobunzima obungalindelekanga. Ikhowudi echanekileyo ye-colorectal adenocarcinoma iququzelelwa yinkqubo ye-ICD-10. Ulwandlalo lwePathology lunika ukuqonda kweempawu zalo mhlaza. I-Metastasis, okanye ukusasazeka kwe-tumor kwezinye iindawo zomzimba, yinto ebalulekileyo ekunqumeni i-prognosis kunye neendlela zonyango ze-colorectal adenocarcinoma. Unyango lubandakanya indibaniselwano yotyando, ichemotherapy, kunye nonyango lwemitha, ngokuxhomekeke kwinqanaba kunye nobungakanani bomhlaza. Ukuhlelwa kwe-colorectal adenocarcinoma kunika ulwazi olubalulekileyo malunga nokuba ndlongondlongo kwethumba. Ukuqonda i-pathophysiology ye-colorectal adenocarcinoma kunceda ekuchongeni iithagethi ezinokubakho zonyango. Inkqubo yeqonga ivavanya ubungakanani bomhlaza, iququzelela izigqibo ezifanelekileyo zonyango. Amaxwebhu achanekileyo e-colorectal adenocarcinoma usebenzisa inkqubo yekhowudi ye-ICD-10 CM ibalulekile kwiirekhodi zezempilo. Amanqanaba aphezulu, afana nesigaba sesi-4 se-colorectal adenocarcinoma, sinokufuna indlela yonyango eyingozi. Kubalulekile ukuqonda umahluko phakathi kwe-colorectal carcinoma kunye ne-adenocarcinoma yokuxilongwa ngokuchanekileyo kunye nokulawula. Ukuqaphela izizathu kunye nemingcipheko ehambelana ne-colorectal adenocarcinoma inceda ekukhuseleni kunye nokungenelela kwangaphambili. Ukuhlolwa rhoqo kunye nokhathalelo lwezonyango ngexesha elifanelekileyo ludlala indima ebalulekileyo ekuphuculeni iziphumo kubantu abane-colorectal adenocarcinoma.

KwiColorectal Adenocarcinoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neColorectal Adenocarcinoma ingaba ayinamsebenzi ukuba kukuphi ukutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngeColorectal Adenocarcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno yeButterbur ityiwa kakhulu xa ithelekiswa nekhaphetshu elimhlophe? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kuneRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut ngaphezu kweChestnut yaseYurophu kunye neentyatyambo ezifana neGram Bean phezu kweYardlong Bean. Kwaye ukuba into endiyityayo ibalulekile - ke umntu uchonga njani ukutya okucetyiswayo kwi-Colorectal Adenocarcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwiColorectal Adenocarcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo i-Pummelo iqulethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Kwaye i-Raspberry ebomvu iqulethe izithako ezisebenzayo i-Quercetin, i-Curcumin, i-Ellagic Acid, i-Daidzein, i-Isoliquiritigenin kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Colorectal Adenocarcinoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo seColorectal Adenocarcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Colorectal Adenocarcinoma?

Izondlo zomntu zomhlaza ezifana neColorectal Adenocarcinoma ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Colorectal Adenocarcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neColorectal Adenocarcinoma

Zonke ii-cancer ezifana ne-Colorectal Adenocarcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Colorectal Adenocarcinoma. Iindlela ze-Biochemical ezifana ne-Angiogenesis, i-PI3K-AKT-MTOR Ukubonakaliswa, Ukubonakaliswa kwe-MAPK, Ukubonakaliswa kwe-RAS-RAF kuyingxenye yenkcazo yesignesha ye-Colorectal Adenocarcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Colorectal Adenocarcinoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiColorectal Adenocarcinoma xa uthatha unyango lomhlaza iFluorouracil, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-APC, i-KRAS, i-TOP2A kunye ne-FBXW7 zezona ziphezulu kudidi lwemfuza ezixeliweyo ze-Colorectal Adenocarcinoma. I-TP53 ixelwe kwi-2.8% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-APC ichazwe kwi-2.7%. Idatha yezigulane ezidityanisiweyo zibandakanya iminyaka ukusuka kwi-4 ukuya kuma-95. I-54.9 % yedatha yesigulane ichongwa njengamadoda. I-Colorectal Adenocarcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeColorectal Adenocarcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR okanye IKHABHAGEJI EMHLOPHE?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Myricetin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, ukubonakaliswa kwe-NFKB, i-Epithelial kwi-Mesenchymal Transition kunye ne-Netrin Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kwi-Colorectal Adenocarcinoma xa unyango lomhlaza oluqhubekayo i-Fluorouracil. Oku kungenxa yokuba i-Giant Butterbur ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seFluorouracil.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-White Cabbage yi-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye ne-Nucleotide metabolism kunye nezinye. Ikhaphetshu emhlophe ayikhuthazwa ukuba i-Colorectal Adenocarcinoma xa unyango lomhlaza oluqhubekayo i-Fluorouracil kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA NGAPHEZU KWEKHABHUJI EMHLOPHE YE-Colorectal Adenocarcinoma KUNYE NONYANGO I-Fluorouracil.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Ellagic Acid, i-Daidzein, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-NFKB Signaling, i-Epithelial ukuya kwi-Mesenchymal Transition, i-PI3K-AKT-MTOR yokuSayina kunye ne-P53 yoMbonakaliso kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Colorectal Adenocarcinoma xa unyango oluqhubekayo lomhlaza luyi-Fluorouracil. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo we-Fluorouracil.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Quercetin, i-Curcumin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nokulungiswa kwe-DNA kunye nezinye. IPummelo ayikhuthazwa kwiColorectal Adenocarcinoma xa unyango lomhlaza oluqhubekayo luyiFluorouracil kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU ESIQINISEKISO ESIQINISELWEYO PHEZU KWE-PUMMELO YE-Colorectal Adenocarcinoma KUNYE NONYANGO I-Fluorouracil.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Myricetin, i-Daidzein, i-Caffeic Acid, i-Apigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-NFKB Signaling, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Netrin Signaling kunye nabanye. I-Butternut iyacetyiswa nge-Colorectal Adenocarcinoma xa unyango lomhlaza oluqhubekayo i-Fluorouracil. Oku kungenxa yokuba iButternut ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seFluorouracil.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Curcumin, i-Ellagic Acid, i-Myricetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Nucleotide metabolism, i-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Chestnut yaseYurophu ayicetyiswa ukuba i-Colorectal Adenocarcinoma xa unyango lomhlaza oluqhubekayo i-Fluorouracil kuba ilungisa ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT YE-Colorectal Adenocarcinoma KUNYE NONYANGO I-Fluorouracil.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuza ye-Colorectal Adenocarcinoma okanye imbali yosapho uthi "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD LEEK okanye SWEDE?

I-Vegetable Wild Leek iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin, i-Isoliquiritigenin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-PI3K-AKT-MTOR yokuSayina, ii-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Wild Leek icetyiswa kumngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba iWild Leek yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSweden yi-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Stem Cell Signaling, i-TGFB Signaling kunye ne-WNT Beta Catenin Signaling kunye nezinye. I-Swede ayikhuthazwa xa umngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-APC kuba inyusa iindlela zokutyikitya kuyo.

I-LEEK YASEMTHETHO YOMFUNO ICEBISIWE PHEZU KWESWEDE NGE-APC genetic RISK YOMHLAZA.

Khetha Fruit NANCE okanye SAPODILLA?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Myricetin, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Angiogenesis, i-Cell Cycle kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Nance icetyiswa kumngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeSapodilla yi-Curcumin, i-Lupeol, i-Myricetin, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye ne-Cell Cycle kunye nezinye. I-Sapodilla ayikhuthazwa xa umngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-APC kuba inyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWESAPODILLA YE-APC genetic RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lupeol, i-Myricetin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Angiogenesis, i-Cell Cycle kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Hazelnut eqhelekileyo iyacetyiswa kumngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Curcumin, i-Ellagic Acid, i-Lupeol, i-Myricetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye ne-TGFB Signaling kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Colorectal Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-APC kuba yonyusa iindlela zokutyikitya.

I-HAZELNUT EQHELEKILEYO KUCEBISWA NGAPHEZU KWE-CHESTNUT YE-APC GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neColorectal Adenocarcinoma. Izigulana zeColorectal Adenocarcinoma kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezinje ngeColorectal Adenocarcinoma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Colorectal Adenocarcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Coad Caseccc 2015
• Ukudibanisa okuphindaphindiweyo kwe-R-spondin kumhlaza wekoloni.
• Ukulungiswa kwe-DNA kunye nemisebenzi ye-redox kunye ne-inhibitors ye-apurinic / i-apyrimidinic endonuclease 1 / i-redox effector factor 1 (i-APE1 / i-Ref-1): uhlalutyo oluthelekisayo kunye nomda wabo kunye nemida ekuphuhlisweni kweziyobisi ze-anticancer.
• I-citrus flavonoid naringenin ivuselela ukulungiswa kwe-DNA kwiiseli zomhlaza we-prostate.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• Inkqubela phambili yophando kwiziphumo ze-anticancer ye-vitamin K2.
• Ulawulo olubi lwe-transducer yesignali kunye ne-activator ye-transcription-3 yokubonisa i-cascade yi-lupeol inqanda ukukhula kwaye yenza i-apoptosis kwiiseli ze-hepatocellular carcinoma.