Ukutya kweAnaplastic Thyroid Cancer!

intshayelelo

Ukutya kwe-Anaplastic Thyroid Cancer kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kulungiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Kwi-Anaplastic Thyroid Cancer ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Anaplastic Thyroid Cancer ingaba ibalulekile into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele ukuba umhlaza onje ngeAnaplastic Thyroid Cancer?

Umzekelo ingaba inomsebenzi ukuba iCauliflower yemifuno ityiwa kakhulu xa ithelekiswa ne-Arrowhead? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyakhethwa kune Cherry emuncu? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut phezu kweFlaxseed kunye nezityalo ezifana ne-Pea enamehlo aMnyama phezu kweLima Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Anaplastic Thyroid Cancer kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Anaplastic Thyroid Cancer!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo iQuercetin, Curcumin, Isoliquiritigenin, Caffeine, Formononetin. Kwaye iCherry emuncu iqulethe izithako ezisebenzayo iQuercetin, iCurcumin, i-Isoliquiritigenin, iFormononetin, iLinalool kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Anaplastic Thyroid Cancer - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi intsalela. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Anaplastic Thyroid Cancer.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Anaplastic Thyroid Cancer?

Izondlo zomntu zomhlaza ezifana neAnaplastic Thyroid Cancer ziquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Anaplastic Thyroid Cancer biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neAnaplastic Thyroid Cancer

Yonke imihlaza efana ne-Anaplastic Thyroid Cancer inokubonakaliswa ngeseti eyodwa yeendlela ze-biochemical - iindlela zokutyikitya ze-Anaplastic Thyroid Cancer. Iindlela ze-Biochemical ezifana ne-RAS-RAF Signaling, i-Inositol Phosphate Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Apoptosis iyingxenye yenkcazo yesignesha ye-Anaplastic Thyroid Cancer. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Anaplastic Thyroid Cancer kufuneka luthathele ingqalelo utyikityo lweendlela zebhayomichi enxulumene nesigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Anaplastic Thyroid Cancer xa uthatha unyango lomhlaza weTrametinib, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TERT, i-TP53, i-BRAF, i-NRAS kunye ne-CREBBP zezona zixeliweyo zemfuza ze-Anaplastic Thyroid Cancer. I-TERT ixelwe kwi-39.2% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-TP53 ichazwe kwi-39.2%. Idatha ehlanganisiweyo yedatha yesigulane igubungela iminyaka yobudala ukusuka kuma-34 ukuya kuma-82. I-54.2 % yedatha yesigulane ichongwa njengamadoda. Ibhayoloji ye-Anaplastic Thyroid Cancer kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Anaplastic Thyroid Cancer

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha imifuno ye-CAULIFLOWER okanye i-ARROWHEAD?

I-Cauliflower yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Isoliquiritigenin, i-Formononetin, i-Catechol, i-Delphinidin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-Inositol Phosphate Signaling, i-RAS-RAF Signaling kunye ne-JAK-STAT Signaling kunye nabanye. ICauliflower iyacetyiswa kwi-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yiTrametinib. Oku kungenxa yokuba iCauliflower ilungisa ezo ndlela zebhayochemicals ekuye kwaxelwa ngazo ngokwenzululwazi ukuba zinike impembelelo yeTrametinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Arrowhead yi-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Caffeine, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Umqondiso kunye nokulungiswa kweDNA kunye nabanye. I-Arrowhead ayikhuthazwa ukuba i-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yi-Trametinib kuba iguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CAULIFLOWER YOMFUNO INCEBISWA NGAPHEZU KWE-ARROWHEAD YE-Anaplastic Thyroid Cancer KUNYE NONYANGO lweTrametinib.

Khetha iSiqhamo SOUR CHERRY okanye iPUMMELO?

I-Fruit Sour Cherry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Isoliquiritigenin, i-Formononetin, i-Linalool. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-PI3K-AKT-MTOR yokuSayina kunye ne-MAPK yokuSayina kunye nabanye. I-Sour Cherry icetyiswa kwi-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yiTrametinib. Oku kungenxa yokuba iSour Cherry ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seTrametinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Quercetin, i-Curcumin, i-Isoliquiritigenin, i-Caffeine, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye nokulungiswa kweDNA kunye nezinye. IPummelo ayikhuthazwa kwi-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yiTrametinib kuba luguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO SOUR CHErry IYAKUNXITSHWA NGAPHEZU KWE-PUMMELO YE-Anaplastic Thyroid Cancer KUNYE NONYANGO I-Trametinib.

Khetha i-Nutt BUTTERNUT okanye i-FLEXSEED?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Caffeine, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, i-JAK-STAT yokuSayina kunye ne-Insulin Signaling kunye nabanye. I-Butternut icetyiswa kwi-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yiTrametinib. Oku kungenxa yokuba i-Butternut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seTrametinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Flaxseed yi-Curcumin, i-Myricetin, i-Isoliquiritigenin, i-Formononetin, i-Catechol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-JAK-STAT Signaling, i-PI3K-AKT-MTOR Umqondiso kunye nokulungiswa kweDNA kunye nabanye. I-Flaxseed ayikhuthazwa kwi-Anaplastic Thyroid Cancer xa unyango lomhlaza oluqhubekayo yi-Trametinib kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT IYACEBISWA NGAPHEZU KWEFLAXSEED YE-Anaplastic Thyroid Cancer KUNYE NONYANGO lweTrametinib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwayo ngabantu abasengozini yemfuzo ye-Anaplastic Thyroid Cancer okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable BITTER GOURD okanye ROCKET SALAD (SSP.)?

I-Vegetable Bitter Gourd iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Myricetin, i-Formononetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-JAK-STAT Signaling, i-PI3K-AKT-MTOR yoMbonakaliso kunye ne-Growth Factor Signaling kunye nabanye. UBitter Gourd ucetyiswa kumngcipheko we-Anaplastic Thyroid Cancer xa umngcipheko wemfuzo ohambelana ne-BRAF. Oku kungenxa yokuba iBitter Gourd yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Rocket Salad (ssp.) I-Curcumin, i-Quercetin, i-Apigenin, i-Myricetin, i-Lycopene. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. Isaladi ye-Rocket (ssp.) ayikhuthazwa xa umngcipheko we-Anaplastic Thyroid Cancer xa umngcipheko wezofuzo unxulumene ne-BRAF kuba inyusa iindlela zokutyikitya kuyo.

IGAMA ELIBUNCU LWEMIFUNO IYAKUNCEBISWA NGE-ROCKET SALAD (SSP.) NGE-BRAF genetic RISK YOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye iFIG?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Curcumin, i-Quercetin, i-Formononetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, i-JAK-STAT Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Red Raspberry iyacetyiswa kumngcipheko we-Anaplastic Thyroid Cancer xa umngcipheko wemfuzo ohambelana ne-BRAF. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo Umzobo yi-Curcumin, i-Quercetin, i-Linalool, i-Lycopene, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-PI3K-AKT-MTOR i-Signaling kunye ne-Growth Factor Signaling kunye nabanye. I-Fig ayikhuthazwa xa umngcipheko we-Anaplastic Thyroid Cancer xa umngcipheko wezofuzo unxulumene ne-BRAF kuba inyusa iindlela zokutyikitya.

ISIQHAMO ESIBOMVU IRASPBHARI IYAKUCEBISWA NGAPHEZU KWEFIG YEBRAF genetic RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Myricetin, i-Lycopene, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Angiogenesis, i-RAS-RAF Signaling, i-JAK-STAT Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Hazelnut eqhelekileyo iyacetyiswa kumngcipheko we-Anaplastic Thyroid Cancer xa ingozi yemfuzo enxulumene ne-BRAF. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Ellagic Acid, i-Curcumin, i-Quercetin, i-Apigenin, i-Myricetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Anaplastic Thyroid Cancer xa umngcipheko wezofuzo unxulumene ne-BRAF kuba inyusa iindlela zokutyikitya.

IHAZELNUT EQHELEKILEYO INCEBISIWE KWI-CHESTNUT YAseYurophu NGE-BRAF genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Anaplastic Thyroid Cancer. Izigulana ze-Anaplastic Thyroid Cancer kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Anaplastic Thyroid Cancer, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neCauliflower kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Anaplastic Thyroid Cancer?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
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