Ukutya kwe-Uterine Epithelioid Leiomyosarcoma!

intshayelelo

Ukutya kwe-Uterine Epithelioid Leiomyosarcoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Kwi-Uterine Epithelioid Leiomyosarcoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu wesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwii-cancer ezifana ne-Uterine Epithelioid Leiomyosarcoma ingaba ayinamsebenzi ukuba kukuphi ukutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekelwe kwisityalo oko kwanele umhlaza onjenge-Uterine Epithelioid Leiomyosarcoma?

Umzekelo ingaba inomsebenzi ukuba imifuno yeGarden Cress ityiwa kakhulu xa ithelekiswa nePrairie Turnip? Ngaba kuyawenza umahluko ukuba isiqhamo iMammee Apple siyakhethwa kuneEvergreen Blackberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neWalnut eqhelekileyo phezu kwe-Macadamia Nut kunye neepulses ezifana ne-Black-eyed Pea phezu kwe-Mung Bean. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Uterine Epithelioid Leiomyosarcoma kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwi-Uterine Epithelioid Leiomyosarcoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo i-Apple ye-Mammee iqulethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lupeol, i-Lycopene, i-Daidzein. Kwaye i-Evergreen Blackberry iqulethe izithako ezisebenzayo i-Ellagic Acid, i-Linalool, i-Eugenol, i-Beta-ionone, i-Alpha Pinene kunye nezinye ezinokwenzeka.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Uterine Epithelioid Leiomyosarcoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Uterine Epithelioid Leiomyosarcoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Uterine Epithelioid Leiomyosarcoma?

Izondlo zomntu zomhlaza ezifana ne-Uterine Epithelioid Leiomyosarcoma iquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Uterine Epithelioid Leiomyosarcoma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Uterine Epithelioid Leiomyosarcoma

Zonke ii-cancer ezifana ne-Uterine Epithelioid Leiomyosarcoma inokubonakaliswa ngesethi ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Uterine Epithelioid Leiomyosarcoma. Iindlela ze-Biochemical ezifana ne-TGFB Signaling, i-Apoptosis, ii-Checkpoints ze-Cell Cycle, i-Cell Cycle ziyingxenye yenkcazo yesignesha ye-Uterine Epithelioid Leiomyosarcoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Uterine Epithelioid Leiomyosarcoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali ezihambelana nesigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezelelo ziyacetyiswa kwi-Uterine Epithelioid Leiomyosarcoma xa uthatha unyango lomhlaza wePaclitaxel, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-PDGFRB, i-ATRX, i-MED12 kunye ne-BRD4 zezona ziphezulu iijene ezixeliweyo ze-Uterine Epithelioid Leiomyosarcoma. I-TP53 ixelwe kwi-66.7% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-PDGFRB ichazwe kwi-33.3%. Idatha yesigulana esidityanisiweyo igubungela iminyaka ukusuka ukuya . I-0.0% yedatha yesigulane ichongwa njengamadoda. I-Uterine Epithelioid Leiomyosarcoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo ze-Uterine Epithelioid Leiomyosarcoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GARDEN CRESS okanye PRAIRIE TURNIP?

I-Vegetable Garden Cress iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Daidzein, i-Phloretin, i-Bergapten. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-Apoptosis kunye nezinye. I-Garden Cress icetyiswa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango oluqhubekayo lomhlaza yi-Paclitaxel. Oku kungenxa yokuba iGarden Cress ilungisa ezo ndlela zebhayoloji eziye zaxelwa ngokwesayensi ukwazisa isiphumo sePaclitaxel.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Prairie Turnip yi-Apigenin, i-Curcumin, i-Lupeol, i-Lycopene, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Prairie Turnip ayikhuthazwa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango lomhlaza oluqhubekayo i-Paclitaxel kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CRESS YEGADI YEMIFUNO IYAKUGQIBISWA NGAPHEZU KWE-PRAIRIE TURNIP YE-Uterine Epithelioid Leiomyosarcoma KUNYE NONYANGO lwe-Paclitaxel.

Khetha iFruit EVERGREEN BLACKBERRY okanye MAMMEE APPLE?

Isiqhamo iEvergreen Blackberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Linalool, i-Eugenol, i-Beta-ionone, i-Alpha Pinene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayomichi efana neSeli Cycle, i-Apoptosis kunye ne-MYC Signaling kunye nezinye. I-Evergreen Blackberry iyacetyiswa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango lomhlaza oluqhubekayo yi-Paclitaxel. Oku kungenxa yokuba i-Evergreen Blackberry ilungisa ezo ndlela zebhayochemicals eziye zaxelwa ngokwesayensi ukwazisa isiphumo sePaclitaxel.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeMammee Apple ziyi-Apigenin, i-Curcumin, i-Lupeol, i-Lycopene, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-TGFB Signaling kunye nezinye. I-Mammee Apple ayikhuthazwa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango lomhlaza oluqhubekayo i-Paclitaxel kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO EVERGREEN BLACKBERRY KUNCEBISWA NGAPHEZU KWE-MAMMEE APPLE NGE-Uterine Epithelioid Leiomyosarcoma KUNYE NONYANGO lwe-Paclitaxel.

Khetha i Nut COMMON WALNUT okanye MACADAMIA NUT?

I-Walnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Ellagic Acid, i-Daidzein, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Apoptosis kunye ne-TGFB Signaling kunye nezinye. I-Walnut eqhelekileyo inconywa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango oluqhubekayo lomhlaza yi-Paclitaxel. Oku kungenxa yokuba i-Walnut eqhelekileyo iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zenze impembelelo ye-Paclitaxel.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Macadamia Nut yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo zebhayochemicals ezifana neTGFB Signaling kunye neMYC Signaling kunye nezinye. I-Macadamia Nut ayikhuthazwa kwi-Uterine Epithelioid Leiomyosarcoma xa unyango lomhlaza oluqhubekayo yi-Paclitaxel kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IWALNUT EQHELEKILEYO IYANCEBISWA NGE-MACADAMIA NUT YE-Uterine Epithelioid Leiomyosarcoma KUNYE NONYANGO lwePaclitaxel.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Uterine Epithelioid Leiomyosarcoma okanye imbali yosapho "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or MALABAR SPINACH?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lycopene, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nezinye. I-Butterbur enkulu iyacetyiswa kumngcipheko we-Uterine Epithelioid Leiomyosarcoma xa ingozi yemfuzo ehambelana nayo yi-ATRX. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno iMalabar Isipinashi yi-Apigenin, i-Curcumin, i-Lycopene, i-Quercetin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Histone Methylation kunye nabanye. I-Malabar Spinach ayikhuthazwa xa umngcipheko we-Uterine Epithelioid Leiomyosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYAKUCEBISWA NGAPHEZU KWE-MALABAR SPINACH NGE-ATRX genetic RISK OF CANCER.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Red Raspberry inconywa kumngcipheko we-Uterine Epithelioid Leiomyosarcoma xa umngcipheko wezofuzo ohambelana ne-ATRX. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo yi-Apigenin, i-Curcumin, i-Lycopene, i-Quercetin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, ukulungiswa kwe-DNA kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Pummelo ayikhuthazwa xa umngcipheko we-Uterine Epithelioid Leiomyosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba inyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO ESIQINISEKILEYO PHEZU KWE-PUMMELO YE-ATRX GENETIC RISK YOMHLAZA.

Khetha Nut COMMON HAZELNUT okanye CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lycopene, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-P53 Signaling kunye ne-MYC Signaling kunye nabanye. I-Hazelnut eqhelekileyo inconywa kumngcipheko we-Uterine Epithelioid Leiomyosarcoma xa ingozi yemfuza ehambelana nayo i-ATRX. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Uterine Epithelioid Leiomyosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yandisa iindlela zokutyikitya.

I-HAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-CHESTNUT YE-ATRX GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Uterine Epithelioid Leiomyosarcoma. Izigulana ze-Uterine Epithelioid Leiomyosarcoma kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Uterine Epithelioid Leiomyosarcoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunje ngeGarden Cress kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Uterine Epithelioid Leiomyosarcoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
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• I-Lycopene ngokwahlukileyo idala i-quiescence kunye ne-apoptosis kwi-androgen-esabelayo kunye ne-independent ye-prostate cancer celllines.
• I-asidi ye-Gallic ixhokonxa umonakalo we-DNA kwaye icinezela i-DNA yokulungisa i-gene expression kwi-prostate cancer yomntu iiseli ze-PC-3.