Ukutya kweUrethral Squamous Cell Carcinoma!

intshayelelo

Ukutya kwe-Urethral Squamous Cell Carcinoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza - ukukhetha ukutya oza kukutya asingomsebenzi olula.

Kwi-Urethral Squamous Cell Carcinoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngesondlo obubuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza womhlaza onje nge-Urethral Squamous Cell Carcinoma ingaba inomsebenzi wokutya endikutyayo okanye endingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanela umhlaza ofana ne-Urethral Squamous Cell Carcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno ye-Olive ityiwa kakhulu xa ithelekiswa ne-Swede? Ngaba kuyawenza umahluko ukuba isiqhamo iSoursop siyakhethwa kuneBlackberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neCashew Nut phezu kweHazelnut kunye nezityalo ezifana neGreen Bean phezu kwePigeon Pea. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Urethral Squamous Cell Carcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Urethral Squamous Cell Carcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iSoursop iqulethe izithako ezisebenzayo Isoliquiritigenin, Myricetin, Luteolin, Curcumin, Delphinidin. Kwaye iBlackberry iqulethe izithako ezisebenzayo iQuercetin, iMethyleugenol, i-Ellagic Acid, iMyricetin, iLinalool kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Urethral Squamous Cell Carcinoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi intsalela. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Urethral Squamous Cell Carcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Urethral Squamous Cell Carcinoma?

Isondlo esilungiselelwe wena somhlaza njenge-Urethral Squamous Cell Carcinoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Urethral Squamous Cell Carcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba semngciphekweni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Urethral Squamous Cell Carcinoma

Zonke ii-cancer ezifana ne-Urethral Squamous Cell Carcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Urethral Squamous Cell Carcinoma. Iindlela ze-Biochemical ezifana ne-RAS-RAF Ukubonakaliswa, ukulungiswa kwe-DNA, i-Oncogenic Histone Methylation, i-MAPK Ukubonakaliswa yinxalenye yenkcazo yesignesha ye-Urethral Squamous Cell Carcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Urethral Squamous Cell Carcinoma kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Urethral Squamous Cell Carcinoma xa uthatha unyango lomhlaza IRadiation, kunye nokunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-BLM, i-BRCA1, i-CTCF, i-KMT2C kunye ne-MAP3K13 zezona ziphezulu iigenes ezixeliweyo ze-Urethral Squamous Cell Carcinoma. I-BLM ixelwe kwi-50.0% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-BRCA1 ixelwe kwi-50.0%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-100.0 % yedatha yesigulane ichongwa njengamadoda. I-Urethral Squamous Cell Carcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo ze-Urethral Squamous Cell Carcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable OIVE okanye SWEDE?

Imifuno ye-Olive iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Myricetin, i-Isoliquiritigenin, i-Kaempferol, i-Curcumin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-RAS-RAF Signaling kunye nezinye. Umnquma uyacetyiswa kwi-Urethral Squamous Cell Carcinoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba uMnquma ulungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSweden yi-Isoliquiritigenin, i-Curcumin, i-Delphinidin, i-Protocatechuic Acid, i-Geraniol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye nezinye. I-Swede ayikhuthazwa kwi-Urethral Squamous Cell Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

UMNQUMO WOMNTU UYCEBISWA NGAPHEZU KWESWEDE NGE-Urethral Squamous Cell Carcinoma KUNYE NONYANGO LWERadiation.

Khetha iSiqhamo BLACKBERRY okanye SOURSOP?

I-Fruit Blackberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Methyleugenol, i-Ellagic Acid, i-Myricetin, i-Linalool. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-RAS-RAF Signaling kunye nezinye. I-Blackberry iyacetyiswa kwi-Urethral Squamous Cell Carcinoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba i-Blackberry ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo ze-Soursop ziyi-Isoliquiritigenin, i-Myricetin, i-Luteolin, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye nezinye. I-Soursop ayikhuthazwa kwi-Urethral Squamous Cell Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO BLACKBERRY KUNCEBISWA NGAPHEZU KWESOURSOP YE-Urethral Squamous Cell Carcinoma KUNYE NONYANGO LWERadiation.

Khetha i Nut CASHEW NUT okanye HAZELNUT?

I-Cashew Nut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Myricetin, i-Isoliquiritigenin, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-RAS-RAF Signaling kunye nezinye. I-Cashew Nut icetyiswa kwi-Urethral Squamous Cell Carcinoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba iCashew Nut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Hazelnut yi-Isoliquiritigenin, i-Myricetin, i-Kaempferol, i-Curcumin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-RAS-RAF Signaling kunye nezinye. IHazelnut ayikhuthazwa kwi-Urethral Squamous Cell Carcinoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CASHEW UTIYAKUNIKEZWA NGAPHEZU KWEHAZELNUT YE-Urethral Squamous Cell Carcinoma KUNYE NONYANGO LWERadiation.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuzo ye-Urethral Squamous Cell Carcinoma okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD CARROT okanye itawuli yeGOURD?

I-Vegetable Wild Carrot iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Quercetin, i-Linalool, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-P53 Signaling, i-Angiogenesis kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Wild Carrot icetyiswa kumngcipheko we-Urethral Squamous Cell Carcinoma xa ingozi yemfuzo eyayanyaniswa nayo yiBLM. Oku kungenxa yokuba i-Wild Carrot yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Towel Gourd yemifuno yi-Apigenin, i-Curcumin, i-Daidzein, i-Lupeol, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-MAPK Signaling kunye nabanye. I-Towel Gourd ayikhuthazwa xa umngcipheko we-Urethral Squamous Cell Carcinoma xa umngcipheko wezofuzo uhambelana ne-BLM kuba yonyusa iindlela zokutyikitya kuyo.

UMNQATHA WASEMHLANGA WOMFUNO UYCEBISWA PHEZU KWEGANDA YETAWULI NGE-BLM UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Quercetin, i-Daidzein, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-P53 Signaling, i-Angiogenesis, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nezinye. I-Red Raspberry iyacetyiswa kumngcipheko we-Urethral Squamous Cell Carcinoma xa umngcipheko wemfuzo ohambelana ne-BLM. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Daidzein, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Urethral Squamous Cell Carcinoma xa umngcipheko wezofuzo uhambelana ne-BLM kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO ESIQINISEKILEYO PHEZU KWE-PUMMELO NGE-BLM GENETIC RISK YOMHLAZA.

Khetha i Nut COMMON HAZELNUT okanye iFLXSEED?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Daidzein, i-Lupeol, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-P53 Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Hazelnut eqhelekileyo iyacetyiswa kumngcipheko we-Urethral Squamous Cell Carcinoma xa umngcipheko wemfuzo ohambelana ne-BLM. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Flaxseed yi-Apigenin, i-Curcumin, i-Daidzein, i-Lupeol, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Angiogenesis kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Flaxseed ayikhuthazwa xa umngcipheko we-Urethral Squamous Cell Carcinoma xa umngcipheko wezofuzo uhambelana ne-BLM kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGAPHEZU KWEFLAXSEED YE-BLM UMNGCIPHEKO WEMFUZO YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Urethral Squamous Cell Carcinoma. Izigulana ze-Urethral Squamous Cell Carcinoma kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Urethral Squamous Cell Carcinoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunjengoMnquma kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Urethral Squamous Cell Carcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
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• Imiphumo ye-antitumor ye-geraniol: Ukumodareyithwa kweendlela eziphawulekayo zomhlaza (Uphononongo).
• Iingcamango ezintsha kwi-phospholipase D ebonisa ukuvuvukala kunye nomhlaza.