Ukutya kwamathumbu amancinci Neuroendocrine Tumor!

intshayelelo

Ukutya kweThumbu eliNcinane I-Neuroendocrine Tumor kufuneka ibe yeyomntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Izibilini ezincinci ze-neuroendocrine, uhlobo lomhlaza osuka kwiiseli ze-neuroendocrine kumathumbu amancinci, ziyaziwa ngeempawu zazo ezizodwa kunye nokuziphatha. I-radiology, ngakumbi i-CT scans, idlala indima ebalulekileyo ekuxilongeni la mathumba, ahlala eqaqambisa kwiingxoxo ezineenkcukacha kwiRadiopaedia. Ikhowudi ye-ICD-10 ye-tumor encinci ye-neuroendocrine inceda ekuhleleni kwabo kunye nokulinganisa amaxwebhu onyango. Izigulane zinokufumana uluhlu lweempawu, kubandakanywa intlungu yesisu kunye noshintsho kwimikhwa yamathumbu, nto leyo efuna ukuqhutyelwa ngokucokisekileyo ukuxilongwa ngokuchanekileyo. Inkcazo ye-pathology yezi thumba inika ulwazi olubalulekileyo kukwakheka kweeselfowuni, kubalulekile ekumiseleni unyango olufanelekileyo, oluhlala lubandakanya utyando kwaye lunokubandakanya unyango olujoliswe kuyo okanye ichemotherapy. Ukulinganisa kubaluleke kakhulu ekuhloleni ubungakanani besi sifo kunye nokwazisa nge-prognosis, kunye namathumba ebakala 1 ngokubanzi anembono engcono. I-CAP protocol ye-tumor encinci ye-neuroendocrine ibeka umgangatho wovavanyo lwe-pathological, iqinisekisa ukuhambelana kokuxilongwa kunye nokucwangciswa kwonyango. Imiba yemfuza kunye namacandelo elifa yimimandla yophando oluqhubekayo, enika ulwazi malunga nophuhliso kunye nokuqhubela phambili kwala mathumba. Ukuqonda imfuzo kunokunceda ekuchongeni abantu abasengozini enkulu. Ukugcina usexesheni ngolwazi lwamva nje, olufana nolo lufunyenwe kwimithombo yezonyango efana ne-UpToDate, kubalulekile kubasebenzi bezempilo abalawula la mathumba anzima. Indlela iyonke kwi-tumor ye-neuroendocrine yamathumbu amancinci ifuna isicwangciso esinamacala amaninzi, esibandakanya ukuxilongwa ngokuchanekileyo, isiteji, kunye nesicwangciso sonyango esilungiselelwe ukuphucula iziphumo zesigulane.

Kwi-Tumor encinci ye-Neuroendocrine Tumor ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza womhlaza onje ngamathumba amaNcinci iNeuroendocrine Tumor ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngeTumor eNcinci ye-Neuroendocrine Tumor?

Umzekelo ingaba inomsebenzi ukuba iParsnip yemifuno ityiwa kakhulu xa ithelekiswa neDaikon Radish? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyakhethwa kuneSoursop? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neWalnut emnyama phezu kweChestnut kunye nezityalo ezifana nePea enamehlo aMnyama phezu kwembotyi yeWax emthubi. Kwaye ukuba into endiyityayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Small Bowel Neuroendocrine Tumor kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiThumbu eliNcinci leNeuroendocrine!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo Apigenin, Lupeol, Daidzein, Curcumin, Geraniol. Kwaye i-Soursop iqulethe izithako ezisebenzayo Apigenin, Lupeol, Fisetin, Daidzein, Curcumin kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Small Bowel Neuroendocrine Tumor - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo kwiTumor eNcinci ye-Neuroendocrine Tumor.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiThumbu eliNcinci leNeuroendocrine?

Izondlo zomntu zomhlaza ezifana neThumbu eliNcinci iNeuroendocrine Tumor ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yeTumor ye-Neuroendocrine Tumor, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obuhambelanayo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neTumor encinci ye-Neuroendocrine Tumor

Zonke ii-cancer ezifana ne-Small Bowel Neuroendocrine Tumor inokubonakaliswa ngeseti ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Small Bowel Neuroendocrine Tumor. Iindlela ze-Biochemical ezifana ne-Cell Cycle, i-MAPK Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa, ii-Checkpoints ze-Cell Cycle ziyingxenye yenkcazo yesignesha ye-Small Bowel Neuroendocrine Tumor. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiThumbu eliNcinci leNeuroendocrine kufuneka luthathelwe ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwiThumbu eliNcinci iNeuroendocrine Tumor xa uthatha unyango lomhlaza iLanreotide, kunye nokunye ukutya kunye nezongezo akukhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-CDKN1B, i-NF1, i-TP53, i-TGFBR2 kunye ne-RUNX1T1 zezona ziphezulu iigenes ezixeliweyo ze-Small Bowel Neuroendocrine Tumor. I-CDKN1B ixelwe kwi-14.3% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-NF1 ixelwe kwi-9.5%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-58.8% yedatha yesigulane ichongwa njengamadoda. I-Neuroendocrine Tumor Biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo kwiTumor encinci ye-Neuroendocrine Tumor

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable PARSNIP okanye iDAIKON RADISH?

I-Parsnip yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Lupeol, i-Daidzein, i-Curcumin, i-Geraniol, i-Quercetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-MAPK Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Parsnip icetyiswa kwiTumor encinci ye-Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yiLanreotide. Oku kungenxa yokuba iParsnip ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seLanreotide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeDaikon Radish yi-Apigenin, Lupeol, Daidzein, Curcumin, Geraniol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Daikon Radish ayikhuthazwa kwiTumor encinci ye-Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo i-Lanreotide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-VEGETABLE PARSNIP INCEBISWA NGAPHEZU KWE-DAIKON RADISH YAMATHUNZI Amancinci Neuroendocrine Tumor KUNYE NONYANGO ILanreotide.

Khetha iSiqhamo SOURSOP okanye iPUMMELO?

I-Fruit Soursop iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Lupeol, i-Fisetin, i-Daidzein, i-Curcumin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-MAPK Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Soursop icetyiswa kwi-Small Bowel Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yiLanreotide. Oku kungenxa yokuba iSoursop ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seLanreotide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo ziyi-Apigenin, i-Lupeol, i-Daidzein, i-Curcumin, i-Geraniol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. IPummelo ayikhuthazwa kwiTumor encinci ye-Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yiLanreotide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO SOURSOP IYANCEBISWA NGAPHEZU KWE-PUMMELO YAMATHUNZI AmaNcinane Neuroendocrine Ithumba KUNYE NONYANGO iLanreotide.

Khetha i-Nutt EMNYAMA WALNUT okanye i-CHESTNUT?

I-Walnut emnyama iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Lupeol, i-Ellagic Acid, i-Daidzein, i-Curcumin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-MAPK Signaling kunye nezinye. IWalnut emnyama icetyiswa kwiTumor encinci ye-Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo yiLanreotide. Oku kungenxa yokuba iWalnut emnyama ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seLanreotide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Lupeol, i-Ellagic Acid, i-Daidzein, i-Curcumin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Chestnut ayikhuthazwa kwiTumor encinci ye-Neuroendocrine Tumor xa unyango lomhlaza oluqhubekayo i-Lanreotide kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IWALNUT EMNYAMA KUNCEBISWA NGAPHEZU KWE-CHESTNUT YAMATHUNZI AmaNcinane Neuroendocrine Ithumba KUNYE NONYANGO ILanreotide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Small Bowel Neuroendocrine Tumor okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or SHALLOT?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-P53 Signaling kunye ne-MYC Signaling kunye nabanye. I-Giant Butterbur icetyiswa kumngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wemfuzo ohambelana ne-CDKN1B. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Shallot yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Shallot ayikhuthazwa xa umngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wezofuzo uhambelana ne-CDKN1B kuba inyusa iindlela zokutyikitya kuyo.

IBHUTTERBURE EYISINXIBA YOMFUNO IYAKUCEBISWA NGAPHEZU KWE-SHALLOT YE-CDKN1B UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iSiqhamo RED RASPBERRY okanye iFIG?

Isiqhamo esiBomvu iRaspberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Lupeol, i-Quercetin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Red Raspberry iyacetyiswa kumngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wemfuzo ohambelana ne-CDKN1B. Oku kungenxa yokuba i-Red Raspberry yonyusa ezo ndlela ze-biochemical ezichasene nabaqhubi batyikityo kuyo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo Umzobo yiCurcumin, iLupeol, iQuercetin, iLinalool, iDaidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Growth Factor Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Fig ayikhuthazwa xa umngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wezofuzo uhambelana ne-CDKN1B kuba inyusa iindlela zokutyikitya kuyo.

ISIQHAMO ESIBOMVU ESIQINISEKISO SESIQINISEKISO PHEZU KWE-FIG YE-CDKN1B GENETIC RISK YOMHLAZA.

Khetha i-Nutt EQHELEKILEYO IHAZELNUT okanye i-EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Quercetin, i-Daidzein, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-TGFB Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Hazelnut eqhelekileyo icetyiswa kumngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wemfuzo ohambelana ne-CDKN1B. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Quercetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Small Bowel Neuroendocrine Tumor xa umngcipheko wezofuzo uhambelana ne-CDKN1B kuba yonyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA NGE-CHESTNUT YAseYurophu NGE-CDKN1B genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Small Bowel Neuroendocrine Tumor. Izigulana zeTumor ezincinci kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana neTumor eNcinci ye-Neuroendocrine Tumor, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunje ngeParsnip kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingayikhethi kwiTumor encinci ye-Neuroendocrine?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• I-Pan Origised 2020
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Daidzein icinezela i-tumor necrosis factor-α ebangela ukufuduka kunye nokuhlasela ngokuthintela i-hedgehog / i-Gli1 ukubonakaliswa kwiiseli zomhlaza webele lomntu.
• I-Pelargonidin yenza imiphumo ye-antitumor kwiiseli ze-osteosarcoma zomntu ngokusebenzisa i-autophagy induction, ukulahlekelwa kwe-membrane ye-mitochondrial, ukubanjwa kwe-cell cycle ye-G2 / M kunye nokunciphisa indlela yokubonisa i-PI3K / AKT.
• Imiphumo ye-anticancer ye-asidi ye-ferulic ihambelana nokungeniswa kokubanjwa komjikelo weseli kunye ne-autophagy kwiiseli zomhlaza womlomo wesibeleko.
• I-Paederia foetida yenza umsebenzi we-anticancer ngokumodareyitha i-chromatin modification enzymes kunye nokuguqula i-pro-inflammatory cytokine gene expression kwiiseli zomhlaza we-prostate.
• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.