Ukutya kweSclerosing Epithelioid Fibrosarcoma!

intshayelelo

Ukutya kwe-Sclerosing Epithelioid Fibrosarcoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KwiSclerosing Epithelioid Fibrosarcoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu wesondlo obubuzwa ngabaguli abanomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje ngeSclerosing Epithelioid Fibrosarcoma ingaba inomsebenzi wokutya endikutyayo okanye endingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngeSclerosing Epithelioid Fibrosarcoma?

Umzekelo ingaba inomsebenzi ukuba imifuno yaseWelsh ityiwa kakhulu xa ithelekiswa neMalabar Spinatshi? Ngaba kuyawenza umahluko ukuba isiqhamo seGrapefruit siyakhethwa kune-Evergreen Blackberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neWalnut phezu kweChestnut yaseJapan kunye neepulses ezifana neBroad Bean phezu kwePigeon Pea. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Sclerosing Epithelioid Fibrosarcoma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiSclerosing Epithelioid Fibrosarcoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo, i-Grapefruit iqulethe izithako ezisebenzayo i-Naringenin, i-Curcumin, i-Hesperidin, i-Pelargonidin, i-Isoliquiritigenin. Kwaye i-Evergreen Blackberry iqulethe izithako ezisebenzayo i-Ellagic Acid, i-Linalool, i-Gallic Acid kunye nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo nokukhetha ukutya okutyayo kwi-Sclerosing Epithelioid Fibrosarcoma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seSclerosing Epithelioid Fibrosarcoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiSclerosing Epithelioid Fibrosarcoma?

Izondlo zomntu zomhlaza ezifana neSclerosing Epithelioid Fibrosarcoma iquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Sclerosing Epithelioid Fibrosarcoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neSclerosing Epithelioid Fibrosarcoma

Zonke ii-cancer ezifana ne-Sclerosing Epithelioid Fibrosarcoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Sclerosing Epithelioid Fibrosarcoma. Iindlela ze-Biochemical ezifana ne-TGFB Signaling, i-Cytokine Signaling, i-Hypoxia, i-Energy Metabolism iyingxenye yenkcazo yesignesha ye-Sclerosing Epithelioid Fibrosarcoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiSclerosing Epithelioid Fibrosarcoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo ngeSclerosing Epithelioid Fibrosarcoma xa uthatha unyango lomhlaza Imitha, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-PBRM1, i-TGFBR2, i-ATRX, i-BCOR kunye ne-KMT2A zezona ntlobo zemfuza ezixeliweyo eziphezulu ze-Sclerosing Epithelioid Fibrosarcoma. I-PBRM1 ixelwe kwi-25.0 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-TGFBR2 ichazwe kwi-12.5%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-50.0% yedatha yesigulane ichongwa njengamadoda. I-Sclerosing Epithelioid Fibrosarcoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeSclerosing Epithelioid Fibrosarcoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable WELSH anyanisi okanye i-MALABAR SPINACH?

I-Onion ye-Welsh yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Salicylic Acid, i-Pelargonidin, i-Caffeine, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Welsh Onion iyacetyiswa kwi-Sclerosing Epithelioid Fibrosarcoma xa unyango oluqhubekayo lomhlaza luyiRadiation. Oku kungenxa yokuba i-anyanisi yase-Welsh iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo weRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno i-Malabar Spinach yi-Curcumin, i-Salicylic Acid, i-Pelargonidin, i-Quercetin, i-Beta-carotene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Malabar Spinach ayikhuthazwa ukuba i-Sclerosing Epithelioid Fibrosarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

Itswele LE-WELSH LOKUGQIBELA KUNCEBISWA NGAPHEZU KWE-MALABAR SPINACH NGESclerosing Epithelioid Fibrosarcoma KUNYE NONYANGO lweRadiation.

Khetha isiqhamo EVERGREEN BLACKBERRY okanye GRAPEFRUIT?

Isiqhamo i-Evergreen Blackberry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Linalool, i-Gallic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Evergreen Blackberry iyacetyiswa kwi-Sclerosing Epithelioid Fibrosarcoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba i-Evergreen Blackberry ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seRadiation.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yiNaringenin, Curcumin, Hesperidin, Pelargonidin, Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. IGrapefruit ayikhuthazwa kwiSclerosing Epithelioid Fibrosarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela zebiochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO EVERGREEN BLACKBERRY KUNCEBISWA NGAPHEZU KWEGRAPEFRUIT NGESclerosing Epithelioid Fibrosarcoma KUNYE NONYANGO LWERadiation.

Khetha Nut WALNUT okanye JAPANESE CHESTNUT?

I-Walnut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Salicylic Acid, i-Pelargonidin, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. IWalnut iyacetyiswa ngeSclerosing Epithelioid Fibrosarcoma xa unyango lomhlaza oluqhubekayo yiRadiation. Oku kungenxa yokuba iWalnut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seRadi.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseJapan yi-Curcumin, i-Salicylic Acid, i-Pelargonidin, i-Caffeine, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Chestnut yaseJapan ayicetyiswa ukuba i-Sclerosing Epithelioid Fibrosarcoma xa unyango lomhlaza oluqhubekayo luyiRadiation kuba ilungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-WALNUT INCEBISWA NGAPHEZU KWE-CHESTNUT YASEJAPANESE NGESclerosing Epithelioid Fibrosarcoma KUNYE NONYANGO Imitha.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuzo ye-Sclerosing Epithelioid Fibrosarcoma okanye imbali yosapho uthi "Yintoni endifanele nditye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha imifuno ye-YELLOW BELL PEPPER okanye i-MOUNTAIN YAM?

Yellow Yellow Bell Pepper iqulethe izithako ezininzi ezisebenzayo okanye bioactives ezifana Curcumin, Quercetin, Linalool, Lupeol, Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Apoptosis, i-P53 yokuSayina kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Yellow Bell Pepper icetyiswa kumngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wemfuzo ohambelana ne-ATRX. Oku kungenxa yokuba iYellow Bell Pepper yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Mountain Yam yi-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Mountain Yam ayikhuthazwa xa umngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba inyusa iindlela zokutyikitya kuyo.

IPAPPHA YEBHELLE EMTHULU EYAYINQONGQO YOMFUNO IYCEBISWA PHEZU KWENTABA YAM NGE-ATRX GENETIC RISK YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Hypoxia, i-P53 Signaling kunye ne-MYC Signaling kunye nabanye. I-Nance icetyiswa kumngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wemfuzo ohambelana ne-ATRX. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye neCell Cycle Checkpoints kunye nezinye. I-Pummelo ayikhuthazwa xa umngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yandisa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO YE-ATRX GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye PISTACHIO?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, Hypoxia, P53 Signaling and Cell Cycle Checkpoints kunye nezinye. I-Butternut iyacetyiswa kumngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wemfuzo ohambelana ne-ATRX. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Pistachio yi-Curcumin, i-Quercetin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Extracellular Matrix Remodeling kunye nezinye. I-Pistachio ayikhuthazwa xa umngcipheko we-Sclerosing Epithelioid Fibrosarcoma xa umngcipheko wezofuzo uhambelana ne-ATRX kuba yandisa iindlela zokutyikitya kuyo.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-PISTACHIO YE-ATRX genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neSclerosing Epithelioid Fibrosarcoma. Izigulana ze-Sclerosing Epithelioid Fibrosarcoma kunye nabantu abasengozini yemfuza bahlala benombuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezinje ngeSclerosing Epithelioid Fibrosarcoma, nganye ineemfuza ezahlukeneyo zethumba kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Onion yase-Welsh iqulethe i-bioactives eyahlukeneyo kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye neendawo ezahlukeneyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon yesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Sclerosing Epithelioid Fibrosarcoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• I-Salicylate, i-diflunisal kunye ne-metabolites yazo inqanda i-CBP / p300 kwaye ibonise umsebenzi we-anticancer.
• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.
• Iimpawu ze-Apoptotic kumgca weseli yomhlaza we-prostate: isiphumo se-ellagic acid.