Ukutya kweSarcomatoid Carcinoma Yemiphunga!

intshayelelo

Ukutya kweSarcomatoid Carcinoma Yemiphunga kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Sarcomatoid carcinoma luhlobo lomhlaza olunobundlongondlongo nolunqabileyo olunokuchaphazela amalungu ahlukeneyo, kuquka imiphunga, izintso, idlala lengqula, isinyi, isibindi, ulusu, intloko nentamo. Ukuxilongwa ngokuchanekileyo kunye nokuqonda lo mhlaza kuncediswa yinkcazo ye-pathology, echaza iimpawu kunye neempawu ze-carcinoma ye-sarcomoid. Iimpawu ze-sarcomatoid carcinoma zinokuhluka ngokuxhomekeke kwilungu elichaphazelekayo kodwa zingabandakanya intlungu, ukudumba, kunye nobunzima bokuphefumla kwimeko ye-lung sarcomatoid carcinoma. Amazinga okusinda kwi-sarcomoid carcinoma ayahluka ngokusekwe kwithumba elithile kunye nenqanaba lokuxilongwa. Unyango lwe-carcinoma ye-sarcomatoid luhlala lubandakanya iindlela ezininzi, kubandakanywa utyando, i-chemotherapy, kunye ne-immunotherapy, ngokuxhomekeke kwimeko yomntu. Inkqubo yekhowudi ye-ICD-10 yenza amaxwebhu afanelekileyo kunye nokuhlelwa kwe-carcinoma ye-sarcomatoid kwiirekhodi zonyango. I-Immunohistochemistry idlala indima ekuqinisekiseni ukuxilongwa kunye nezigqibo zonyango ezikhokelayo, ngakumbi kwi-lung sarcomatoid carcinoma. Uphando oluqhubekayo malunga neenguqu ezinokuthi ziguqulwe kunye nonyango olujoliswe kuyo lunceda ekuphuculeni iindlela zonyango kulo mhlaza uhlaselayo. Ngapha koko, unyango lwe-immunotherapy lunokuba nesithembiso njengendlela yonyango enokubakho kwi-sarcomoid carcinoma. Ukuqonda amazinga ahlukeneyo okusinda kwe-carcinoma ye-sarcomatoid kumalungu ahlukeneyo, njenge-bladder kunye nemiphunga, kubalulekile kwizigulana kunye nababoneleli bezempilo. Ngokubanzi, indlela ebanzi yonyango kunye nenkqubela phambili eqhubekayo kuphando inegalelo kwiziphumo ezingcono kubantu abane-carcinoma ye-sarcomoid.

NgeSarcomatoid Carcinoma Yemiphunga ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza - ngoomhlaza onje ngeSarcomatoid Carcinoma Yemiphunga ingaba ibalulekile into yokuba kukutya endikutyayo okanye endingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanela umhlaza onje ngeSarcomoid Carcinoma Yemiphunga?

Umzekelo ingaba inomsebenzi ukuba iCalabash yemifuno ityiwa kakhulu xa ithelekiswa nePepper (c. Frutescens)? Ngaba kuyawenza umahluko ukuba iziqhamo zaseJapan zePersimmon zikhethwa ngaphezu kweRaspberry eBomvu? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neHazelnut eqhelekileyo ngaphezu kweChestnut yaseYurophu kunye neepulses ezifana ne-Adzuki Bean phezu kwe-Common Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwiSarcomatoid Carcinoma Yemiphunga kwaye ingaba yimpendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiSarcomatoid Carcinoma Yemiphunga!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo iPersimmon yaseJapan iqulethe izithako ezisebenzayo Apigenin, Curcumin, Myricetin, Protocatechuic Acid, Daidzein. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Curcumin, i-Ellagic Acid, i-Protocatechuic Acid, i-Daidzein, i-Formononetin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo nokukhetha ukutya okuza kutyiwa kwiSarcomatoid Carcinoma Yemiphunga - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungahoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo seSarcomatoid Carcinoma Yemiphunga.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiSarcomatoid Carcinoma yeMiphunga?

Isondlo esilungiselelwe wena semihlaza efana neSarcomatoid Carcinoma Yemiphunga ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwiSarcomatoid Carcinoma yeLung biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neSarcomatoid Carcinoma yeMiphunga

Yonke imihlaza efana neSarcomatoid Carcinoma Yemiphunga inokuphawulwa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya zeSarcomatoid Carcinoma Yemiphunga. Iindlela ze-Biochemical ezifana ne-Cell Cycle Checkpoints, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Apoptosis, i-RAS-RAF Ukubonakaliswa yinxalenye yenkcazo yesignesha ye-Sarcomatoid Carcinoma ye-Lung. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwiSarcomatoid Carcinoma Yemiphunga kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Sarcomatoid Carcinoma ye-Lung xa uthatha unyango lomhlaza i-Abemaciclib, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-RNF43, i-MET, i-NRAS kunye ne-KRAS zezona ntlobo zemfuza ezixeliweyo eziphezulu ze-Sarcomatoid Carcinoma ye-Lung. I-TP53 ixelwe kwi-45.5% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-RNF43 ichazwe kwi-18.2%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-60.0% yedatha yesigulane ichongwa njengamadoda. ISarcomatoid Carcinoma yebhayoloji yemiphunga kunye nofuzo oluxeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeSarcomatoid Carcinoma yeMiphunga

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CALABASH okanye IPEPPER (C. FRUTESCENS)?

ICalabash yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Protocatechuic Acid. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina kunye ne-Cell Cycle Checkpoints kunye nabanye. I-Calabash icetyiswa kwi-Sarcomatoid Carcinoma Yemiphunga xa unyango lomhlaza oluqhubekayo i-Abemaciclib. Oku kungenxa yokuba iCalabash ilungisa ezo ndlela zebhayoloji ezixelwe ngokwesayensi ukuze zikhuthaze isiphumo se-Abemaciclib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Pepper yemifuno (c. Frutescens) yi-Apigenin, i-Curcumin, i-Lycopene, i-Myricetin, i-Protocatechuic Acid. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA, ukubonakaliswa kwe-MAPK kunye ne-Cell Cycle Checkpoints kunye nezinye. Pepper (c. Frutescens) ayikhuthazwa Sarcomatoid Carcinoma Of The Lung xa unyango umhlaza oqhubekayo Abemaciclib kuba iguqula ezo pathways biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-CALABASH YOMFUNO INCEBISWA NGAPHEZU KWEPEPPER (C. FRUTESCENS) NGESarcomatoid Carcinoma Yemiphunga KUNYE NONYANGO Abemaciclib.

Khetha iSiqhamo RED RASPBERRY okanye JAPANESE PERSIMMON?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Ellagic Acid, i-Protocatechuic Acid, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Growth Factor Signaling, i-MAPK Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Sarcomatoid Carcinoma ye-Lung xa unyango lomhlaza oluqhubekayo yi-Abemaciclib. Oku kungenxa yokuba iRaspberry ebomvu iguqula ezo ndlela zebhayoloji eziye zaxelwa ngokwesayensi ukwazisa isiphumo se-Abemaciclib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zaseJapan iPersimmon yi-Apigenin, i-Curcumin, i-Myricetin, i-Protocatechuic Acid, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Cell Cycle Checkpoints kunye nezinye. IPersimmon yaseJapan ayikhuthazwa kwiSarcomatoid Carcinoma Yemiphunga xa unyango lomhlaza oluqhubekayo i-Abemaciclib kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ERED RASPBERRY KUNCEBISWA NGAPHEZU KWEPERSIMMONI YASEJAPANE YESarcomatoid Carcinoma Yemiphunga KUNYE NONYANGO Abemaciclib.

Khetha i-Nutt EQHELEKILEYO IHAZELNUT okanye i-EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lycopene, i-Myricetin, i-Protocatechuic Acid, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuSayina kwe-MAPK kunye ne-Cell Cycle Checkpoints kunye nezinye. IHazelnut eqhelekileyo icetyiswa kwiSarcomatoid Carcinoma Yemiphunga xa unyango lomhlaza oluqhubekayo yi-Abemaciclib. Oku kungenxa yokuba iHazelnut eqhelekileyo iguqula ezo ndlela zebhayoloji ezixelwe ngokwesayensi ukwazisa isiphumo se-Abemaciclib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Myricetin, i-Protocatechuic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Sarcomatoid Carcinoma Yemiphunga xa unyango lomhlaza oluqhubekayo i-Abemaciclib kuba lulungisa ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IHAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-EUROPEY CHESTNUT NGESarcomatoid Carcinoma yeMiphuphu KUNYE NONYANGO Abemaciclib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo yeSarcomatoid Carcinoma Yemiphunga okanye imbali yosapho ithi "Yintoni ekufuneka Ndiyitye Ngokwahlukileyo Ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or KOHLRABI?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Delphinidin, i-Apigenin, i-Lycopene, i-Myricetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-Growth Factor Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Sarcomatoid Carcinoma Yemiphunga xa ingozi yemfuzo eyayanyaniswa nayo yi-KRAS. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Kohlrabi yi-Quercetin, i-Curcumin, i-Delphinidin, i-Formononetin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Kohlrabi ayikhuthazwa xa umngcipheko we-Sarcomatoid Carcinoma Yemiphunga xa umngcipheko wezofuzo uhambelana ne-KRAS kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBUR YEMIZI YEMIFUNO INCEBISIWE PHEZU KWE-KOHLRABI NGE-KRAS GENETIC RISK YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Delphinidin, i-Apigenin, i-Myricetin, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-Growth Factor Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. UNance ucetyiswa kumngcipheko weSarcomatoid Carcinoma Yemiphunga xa ingozi yemfuzo eyayanyaniswa nayo yi-KRAS. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yiQuercetin, Curcumin, Delphinidin, Apigenin, Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko weSarcomatoid Carcinoma Yemiphunga xa umngcipheko wemfuzo unxulunyaniswa ne-KRAS kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO YE-KRAS GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye BRAZIL NUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Delphinidin, i-Apigenin, i-Lycopene, i-Myricetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Apoptosis, i-MAPK Signaling, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nezinye. I-Butternut iyacetyiswa kumngcipheko we-Sarcomatoid Carcinoma Yemiphunga xa ingozi yemfuzo eyayanyaniswa nayo yi-KRAS. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives e-Brazil Nut yi-Ellagic Acid, i-Curcumin, i-Delphinidin, i-Formononetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-RAS-RAF Signaling, i-PI3K-AKT-MTOR Umqondiso kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Brazil Nut ayikhuthazwa xa umngcipheko we-Sarcomatoid Carcinoma Yemiphunga xa umngcipheko wemfuzo ohambelana ne-KRAS kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERNUT KUNCEBISWA NGAPHEZU KWEBRAZIL NUT YEKRAS genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neSarcomatoid Carcinoma Yemiphunga. I-Sarcomatoid Carcinoma Yezigulana ze-Lung kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Sarcomatoid Carcinoma ye-Lung, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okunje ngeCalabash kuqulethe izinto ezahlukeneyo zebhayoloji ngokwemiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo se-addon yesondlo somntu senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Sarcomatoid Carcinoma ye-Lung?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Tmb Mskcc 2018
• Imbonakalo yomhlaba eguqukayo yomhlaza we-metastatic ityhilwe kulandelelwano lwezonyango olulindelekileyo lwezigulana ezili-10,000.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• I-Vitamin C ibulala iiseli zomhlaza we-thyroid ngokusebenzisa inhibition exhomekeke kwi-ROS ye-MAPK / ERK kunye ne-PI3K / AKT iindlela ngeendlela ezahlukeneyo.
• Isiphumo sokuthintela i-Hibiscus protocatechuic acid ekukhuthazeni ithumba kwisikhumba sempuku.
• I-Lycopene ngokwahlukileyo idala i-quiescence kunye ne-apoptosis kwi-androgen-esabelayo kunye ne-independent ye-prostate cancer celllines.
• I-Triggering of transient receptor potential potential vanilloid type 1 (TRPV1) yi-capsaicin induces i-Fas/CD95-mediated apoptosis yeeseli zomhlaza we-urothelial ngendlela exhomekeke kwi-ATM.