Ukutya kweRichter Syndrome!

intshayelelo

Ukutya kwe-Richter Syndrome kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuhlengahlengiswe xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Richter syndrome, i-complication enqabileyo kwaye enzima ye-chronic lymphocytic leukemia (CLL), ibandakanya ukuguqulwa kwe-CLL ibe yindlela eyingozi kakhulu ye-lymphoma. Ubomi obulindelekileyo bale meko kunye ne-prognosis ngokuqhelekileyo ihlwempuzekile, njengoko ibonisa ukunyuka okuphawulekayo kubunzima besi sifo. Unyango lwe-Richter syndrome lucelomngeni kwaye luhlala lubandakanya ukudibanisa i-chemotherapy kunye nonyango olujoliswe kuyo, kuxhomekeke kwimpilo yonke yesigulane kunye neenkcukacha zemeko yabo. Inkcazo ye-Pathology ye-Richter syndrome ibonelela ngengqiqo ebalulekileyo kwiimpawu zeselula kunye nokunceda ukukhokela izigqibo zonyango. Izixhobo ezifana ne-Richter syndrome Wiki zibonelela ngolwazi olufikelelekayo kwizigulane kunye nabanonopheli, ngelixa ukwenzeka kwayo kwizilwanyana, njengezinja, kugxininisa ukubaluleka kwesi sifo kuzo zonke iintlobo. Ukubizwa kwe-'Richter syndrome' kunokuba yinto yokudideka kwabanye, kugxininisa ukubaluleka kwemfundo yesigulane ekuqondeni le meko enzima. Ngeenjongo zekhowudi zonyango, ikhowudi ye-ICD-10 ye-Richter syndrome ekuxolweni ibalulekile ekulandeleni unyango kunye namabango e-inshurensi. Iradiyoloji idlala indima ebalulekileyo ekuxilongeni i-Richter syndrome, kunye neendlela zokucinga ezifana ne-CT scans ezisetyenziselwa ukuhlola ubungakanani bokuqhubeka kwesifo. Inkcazo ye-Richter syndrome ibandakanya ubume bayo njengotshintsho ukusuka kwi-CLL ehamba kancinci ukuya kwi-lymphoma eyingozi, kwaye olu tshintsho lukwacaciswe kwimithombo efana neRadiopaedia. Ngokubanzi, ulawulo lwe-Richter syndrome lufuna indlela ebanzi kunye nenolwazi ukujongana nesimo sayo sobudlova ngokufanelekileyo.

KwiRichter Syndrome ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana ne-Richter Syndrome ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekelwe kwisityalo oko kwanele umhlaza onjengeRichter Syndrome?

Umzekelo ingaba inomsebenzi ukuba imifuno yeCluster Bean ityiwa kakhulu xa ithelekiswa ne-Mexican Groundcherry? Ngaba kuyawenza umahluko ukuba isiqhamo iFox Grape siyakhethwa kuneApricot? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana ne-Almond phezu kwe-Chestnut kunye ne-pulses efana ne-Moth Bean phezu kwe-Common Bean. Kwaye ukuba into endiyityayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Richter Syndrome kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Richter Syndrome!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo, i-Fox Grape iqulethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Beta-sitosterol, i-Phloretin, i-Lupeol. Kwaye iApricot iqulethe izithako ezisebenzayo iCurcumin, iBeta-sitosterol, iPhloretin, iLupeol, iDaidzein kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa kusenziwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Richter Syndrome - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seRichter Syndrome.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiRichter Syndrome?

Isondlo esilungiselelwe wena somhlaza njengeRichter Syndrome siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubungcali kwi-Richter Syndrome biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Richter Syndrome

Zonke ii-cancer ezifana ne-Richter Syndrome zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Richter Syndrome. Iindlela ze-Biochemical ezifana ne-Amino Acid Metabolism, ii-Checkpoints ze-Cell Cycle, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Cell Cycle iyingxenye yenkcazo yesignesha ye-Richter Syndrome. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Richter Syndrome kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Richter Syndrome xa uthatha unyango lomhlaza i-Doxorubicin, kwaye okunye ukutya kunye nezongezo akukhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MYC, NOTCH1, BDKRB1, BRAF kunye ne-CDKN2A zezona zakhi zemfuza zibekwe kwindawo ephezulu ye-Richter Syndrome. I-MYC ixelwe kwi-57.1 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-NOCH1 ixelwe kwi-35.7%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-% yedatha yesigulane ichongwa njengamadoda. I-Richter Syndrome biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeRichter Syndrome

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable CLUSTER BEAN okanye iMEXICAN GROUNDCHERRY?

I-Vegetable Cluster Bean iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Beta-sitosterol, i-Stigmasterol, i-Vitamin C, i-Linolenic Acid, i-Linoleic Acid. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-P53 Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-Cluster Bean icetyiswa kwi-Richter Syndrome xa unyango lomhlaza oluqhubekayo yi-Doxorubicin. Oku kungenxa yokuba i-Cluster Bean ilungisa ezo ndlela zebhayochemicals ekuye kwaxelwa ngazo ngokwenzululwazi ukwazisa isiphumo se-Doxorubicin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseMexico yaseGroundcherry yi-Curcumin, i-Apigenin, i-Beta-sitosterol, i-Phloretin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Mexican Groundcherry ayikhuthazwa kwi-Richter Syndrome xa unyango lomhlaza oluqhubekayo yi-Doxorubicin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IMBOTYI YOMFUNO YEMIZIMBA IYINGCEBISWA NGAPHEZU KWEGROUNDCHERRY YASE-MEXICAN NGE-Richter Syndrome KUNYE NONYANGO I-Doxorubicin.

Khetha iSiqhamo seAPRICOT okanye i-FOX GRAPE?

Iziqhamo zeApricot ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Beta-sitosterol, i-Phloretin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Apoptosis, i-MAPK yokuSayina kunye ne-NFKB yokuSayina kunye nabanye. Iapilkosi iyacetyiswa kwi-Richter Syndrome xa unyango lomhlaza oluqhubekayo yi-Doxorubicin. Oku kungenxa yokuba iApricot iguqula ezo ndlela zenzululwazi ngamachiza ekuye kwaxelwa ngokwenzululwazi ukuba zinike impembelelo ye-Doxorubicin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeFox Grape yiCurcumin, i-Apigenin, iBeta-sitosterol, iPhloretin, iLupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Amino Acid Metabolism kunye ne-Cell Cycle Checkpoints kunye nezinye. IFox Grape ayinconywa kwiRichter Syndrome xa unyango lomhlaza oluqhubekayo yiDoxorubicin kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IAPRICOT YESIQHAMO INCEBISWA NGAPHEZU KOMdiliya WE-FOX NGE-Richter Syndrome KUNYE NONYANGO I-Doxorubicin.

Khetha Nut ALMOND okanye CHESTNUT?

I-almond iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Beta-sitosterol, i-Phloretin, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-P53 Signaling, i-MAPK Signaling kunye ne-MYC Signaling kunye nabanye. I-almond iyacetyiswa kwi-Richter Syndrome xa unyango lomhlaza oluqhubekayo yi-Doxorubicin. Oku kungenxa yokuba i-almond ilungisa ezo ndlela zebhayomichimi eziye zaxelwa ngokwenzululwazi ukuze zikhuthaze isiphumo seDoxorubicin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Curcumin, i-Apigenin, i-Beta-sitosterol, i-Phloretin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Amino Acid Metabolism kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Chestnut ayikhuthazwa kwi-Richter Syndrome xa unyango lomhlaza oluqhubekayo yi-Doxorubicin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-almond INCEBISIWE NGAPHEZU KWE-CHESTNUT YE-Richter Syndrome KUNYE NONYANGO I-Doxorubicin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwayo ngabantu abasengozini yemfuzo ye-Richter Syndrome okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or SWEDE?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Lycopene, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Stem Cell Signaling, i-P53 Signaling kunye ne-MAPK Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Richter Syndrome xa umngcipheko wemfuzo ohambelana ne-BDKRB1. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSweden yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR Ukubonisana kunye nabanye. I-Swede ayikhuthazwa xa umngcipheko we-Richter Syndrome xa umngcipheko wezofuzo uhambelana ne-BDKRB1 kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERBUR YEMIZI YEZIGIDI IYACEBISWA PHEZU KWE-SWEDE NGE-BDKRB1 UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Beta-sitosterol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Stem Cell Signaling, i-P53 Signaling kunye ne-MAPK Signaling kunye nabanye. I-Nance icetyiswa kumngcipheko we-Richter Syndrome xa umngcipheko wemfuzo ohambelana ne-BDKRB1. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo ziyi-Apigenin, i-Curcumin, i-Lupeol, i-Lycopene, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Stem Cell Signaling, i-Amino Acid Metabolism kunye ne-Cell Cycle Checkpoints kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Richter Syndrome xa umngcipheko wemfuzo uhambelana ne-BDKRB1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE KUCEBISWA NGAPHEZU KWE-PUMMELO YE-BDKRB1 GENETIC RISK YOMHLAZA.

Khetha Nut EMNYAMA WALNUT okanye EUROPEAN CHESTNUT?

I-Walnut emnyama iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-MAPK yokuSayina kunye ne-Cell Cycle Checkpoints kunye nezinye. IWalnut emnyama iyacetyiswa kumngcipheko we-Richter Syndrome xa umngcipheko wemfuzo ohambelana ne-BDKRB1. Oku kungenxa yokuba iWalnut Emnyama yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana neStem Cell Signaling kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko we-Richter Syndrome xa umngcipheko wezofuzo uhambelana ne-BDKRB1 kuba yonyusa iindlela zokutyikitya kuyo.

IWALNUT EMNYAMA KUNCEBISWA NGAPHEZU KWE-CHESTNUT YAseYurophu NGE-BDKRB1 IMngcipheko yemfuza yoMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Richter Syndrome. Izigulana zaseRichter Syndrome kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Richter Syndrome, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana ne-Cluster Bean kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Richter Syndrome?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• IVithamin C ibulala ngokukhetha i-KRAS kunye ne-BRAF iiseli zomhlaza eziguqukayo ze-colorectal ngokujolisa kwi-GAPDH.
• I-Geraniol, icandelo lee-oyile ezibalulekileyo zesityalo, ikhuthaza iiseli zomhlaza wekholoni yomntu kwi-5-Fluorouracil unyango.