Ukutya kwePheochromocytoma kunye neParaganglioma!

intshayelelo

Ukutya kwePheochromocytoma kunye neParaganglioma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza - ukukhetha ukutya oza kukutya asingomsebenzi olula.

KwiPheochromocytoma kunye neParaganglioma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa ngabaguli abanomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje ngePheochromocytoma kunye neParaganglioma ingaba ibalulekile na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo ngaba kwanele umhlaza onje ngePheochromocytoma kunye neParaganglioma?

Umzekelo ingaba iyabaluleka na into yokuba imifuno i-Giant Butterbur ityiwa kakhulu xa ithelekiswa netheniphu? Ngaba kuyawenza umahluko ukuba isiqhamo esiSweet Orange sikhethwa ngaphezu kweRabbiteye Blueberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neButternut phezu kweMacadamia Nut kunye neepulses ezifana neGram Bean phezu kweMung Bean. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwiPheochromocytoma kunye neParaganglioma kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiPheochromocytoma kunye neParaganglioma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo I-Orange eSweet iqulethe izithako ezisebenzayo iLuteolin, iPhloretin, iBergapten, iCinnamaldehyde, iLupeol. Kwaye i-Rabbiteye Blueberry iqulethe izithako ezisebenzayo i-Quercetin, i-Eugenol, i-Geraniol, i-Gallic Acid, i-Ferulic Acid kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwiPheochromocytoma kunye neParaganglioma - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Kuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo sePheochromocytoma kunye neParaganglioma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiPheochromocytoma kunye neParaganglioma?

Izondlo zomntu zomhlaza ezifana nePheochromocytoma Kwaye iParaganglioma iqulethe ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Pheochromocytoma kunye ne-Paraganglioma biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba semngciphekweni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana nePheochromocytoma kunye neParaganglioma

Zonke i-cancer ezifana ne-Pheochromocytoma kunye neParaganglioma inokubonakaliswa ngesethi ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya zePheochromocytoma kunye neParaganglioma. Iindlela ze-Biochemical ezifana ne-Vitamin Metabolism, ii-Checkpoints ze-Cell Cycle, i-Molecule yoThutho encinci, i-Post Translation Modification iyingxenye yenkcazo yesiginesha ye-Pheochromocytoma kunye ne-Paraganglioma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Pheochromocytoma kunye neParaganglioma kufuneka ithathelwe ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwiPheochromocytoma kunye neParaganglioma xa uthatha unyango lomhlaza iCyclophosphamide, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-EPAS1, i-AWAT1, i-POLR1A, i-ATRX kunye ne-ACER2 zezona zibalaseleyo kwiijini ezixeliweyo zePheochromocytoma kunye neParaganglioma. I-EPAS1 ixelwe kwi-6.5% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-AWAT1 ixelwe kwi-3.2%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kwi-19 ukuya kuma-83. Ama-45.0 % edatha yezigulane ichongwe njengamadoda. I-Pheochromocytoma kunye ne-Paraganglioma biology kunye ne-genetics exeliweyo kunye kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenza isondlo somntu.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zePheochromocytoma kunye neParaganglioma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or TURNIP?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Epithelial ukuya kwi-Mesenchymal Transition, i-Vitamin Metabolism kunye ne-MAPK Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kwiPheochromocytoma kunye neParaganglioma xa unyango lomhlaza oluqhubekayo yiCyclophosphamide. Oku kungenxa yokuba i-Giant Butterbur ilungisa ezo ndlela ze-biochemical eziye zachazwa ngokwenzululwazi ukuze zikhanyise isiphumo se-Cyclophosphamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Tunip yemifuno yi-Quercetin, i-Ellagic Acid, i-Phloretin, i-Cinnamaldehyde, i-Bergapten. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. Itheniphu ayikhuthazwa iPheochromocytoma kunye neParaganglioma xa unyango lomhlaza oluqhubekayo yiCyclophosphamide kuba luguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYISINQWILI YOMFUNO IYACEBISWA NGENXA YOKUJULA I-Pheochromocytoma kunye neParaganglioma KUNYE NONYANGO ICyclophosphamide.

Khetha iSiqhamo RABBITEYE BLUEBERRY okanye ESWEET ORANGE?

I-Fruit Rabbiteye I-Blueberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Eugenol, i-Geraniol, i-Gallic Acid, i-Ferulic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA, i-Cell Cycle, i-MAPK Signaling kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Rabbiteye Blueberry inconywa kwiPheochromocytoma kunye neParaganglioma xa unyango oluqhubekayo lomhlaza yiCyclophosphamide. Oku kungenxa yokuba i-Rabbiteye Blueberry iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze isiphumo se-Cyclophosphamide.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo ezimnandi zeOrange yiLuteolin, iPhloretin, iBergapten, iCinnamaldehyde, iLupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokuLungiswa kwe-DNA kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Orenji eSweet ayikhuthazwa kwiPheochromocytoma kunye neParaganglioma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO I-RABITEYE BLUEBERRY IYANCEBISWA NGAPHEZU KWE-ORENJI ESWITI NGE-Pheochromocytoma kunye neParaganglioma KUNYE NONYANGO ICyclophosphamide.

Khetha Nut BUTTERNUT okanye MACADAMIA NUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Vitamin Metabolism, ukulungiswa kwe-DNA kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Butternut inconywa kwiPheochromocytoma kunye neParaganglioma xa unyango oluqhubekayo lomhlaza yiCyclophosphamide. Oku kungenxa yokuba iButternut ilungisa ezo ndlela zebhayomichi exelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCyclophosphamide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Macadamia Nut yi-Apigenin, i-Luteolin, i-Myricetin, i-Phloretin, i-Cinnamaldehyde. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical njenge-MAPK Signaling kunye nezinye. I-Macadamia Nut ayikhuthazwa kwi-Pheochromocytoma kunye neParaganglioma xa unyango lomhlaza oluqhubekayo yi-Cyclophosphamide kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT IYAKUNIKEZISWA NGAPHEZU KWE-MACADAMIA NUT YE-Pheochromocytoma kunye neParaganglioma KUNYE NONYANGO ICyclophosphamide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwayo ngabantu abasengozini yemfuza yePheochromocytoma kunye neParaganglioma okanye imbali yosapho "Yintoni endifanele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GARDEN CRESS okanye iROMAINE LETTUCE?

I-Vegetable Garden Cress iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives ezifana ne-Curcumin, i-Lupeol, i-Beta-sitosterol, i-Formononetin, i-Vitamin C. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-P53 Signaling, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Garden Cress icetyiswa kumngcipheko we-Pheochromocytoma kunye neParaganglioma xa umngcipheko wemfuzo uhambelana ne-ACER2. Oku kungenxa yokuba iGarden Cress yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Romaine Lettuce yi-Curcumin, i-Apigenin, i-Lupeol, i-Resveratrol, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Lipid Metabolism kunye ne-P53 Signaling kunye nabanye. I-Romaine Lettuce ayikhuthazwa xa umngcipheko we-Pheochromocytoma kunye neParaganglioma xa umngcipheko wezofuzo uhambelana ne-ACER2 kuba yonyusa iindlela zokutyikitya kuyo.

I-VEGETABLE GARDEN CRESS IYAKUCEBISWA NGAPHEZU KWEROMAINE LETTUCE YE-ACER2 genetic RISK YOMHLAZA.

Khetha iSiqhamo EMNYAMA CROWBERRY okanye GRAPEFRUIT?

Iziqhamo eziMnyama zeCrowberry ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, Hypoxia, P53 Signaling and Post Translation Modification kunye nezinye. I-Black Crowberry icetyiswa kumngcipheko we-Pheochromocytoma kunye neParaganglioma xa umngcipheko wemfuzo ohambelana ne-ACER2. Oku kungenxa yokuba iBlack Crowberry yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yiCurcumin, iLupeol, iLycopene, iFormononetin, iBeta-sitosterol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Lipid Metabolism kunye nezinye. IGrapefruit ayikhuthazwa xa umngcipheko wePheochromocytoma kunye neParaganglioma xa umngcipheko wezofuzo uhambelana ne-ACER2 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO EMNYAMA CROWBERRY KUNCEBISWA NGAPHEZU KWEGRAPEFRUIT NGE-ACER2 genetic RISK YOMHLAZA.

Khetha Nut CHIA okanye HICKORY NUT?

I-Chia iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Lycopene, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, Hypoxia, P53 Signaling kunye ne-MYC Signaling kunye nabanye. I-Chia icetyiswa kumngcipheko we-Pheochromocytoma kunye neParaganglioma xa umngcipheko wemfuzo ohambelana ne-ACER2. Oku kungenxa yokuba i-Chia yonyusa ezo ndlela zebhayoloji ezichasana nabaqhubi abatyikityayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Hickory Nut yi-Curcumin, i-Apigenin, i-Lupeol, i-Lycopene, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Lipid Metabolism kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Hickory Nut ayikhuthazwa xa umngcipheko we-Pheochromocytoma kunye neParaganglioma xa umngcipheko wezofuzo uhambelana ne-ACER2 kuba yonyusa iindlela zokutyikitya kuyo.

I-CHIA ICEBISIWE PHEZU KWE-HICKORY NUT YE-ACER2 genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana nePheochromocytoma kunye neParaganglioma. I-Pheochromocytoma kunye nezigulana zeParaganglioma kunye nabantu abasengozini yemfuza bahlala benombuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezinje ngePheochromocytoma kunye neParaganglioma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye ulwahlulo lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwiPheochromocytoma kunye neParaganglioma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Indlela yemolekyuli ye-luteolin-induced apoptosis inokunxulumana nokuthintelwa kwe-angiogenesis kwiiseli ze-pancreatic carcinoma zabantu.
• Ukungeniswa kwe-apoptosis ye-SW480 yeeseli zomhlaza wekholoni yomntu ngo (-)-epicatechin ekwanti kwi-Bulnesia sarmienti.
• I-citrus flavonoid naringenin ivuselela ukulungiswa kwe-DNA kwiiseli zomhlaza we-prostate.
• I-BRCA1 kunye ne-BRCA2 njengeethagethi ze-molecular for phytochemicals indole-3-carbinol kunye ne-genistein kwi-breast and prostate cancer cells.
• Ukukhula okukhuthazwayo kweeseli ze-pulmonary adenocarcinoma yabantu kunye neeseli ezincinci ze-epithelial zomoya nge-beta-carotene ngokusebenza kwe-cAMP, i-PKA, i-CREB kunye ne-ERK1/2.
• Ukutya kwe-D-glucarate iziphumo kwiimpawu ze-biomarkers zokudumba ngexesha lokuqala kwamanqanaba okuqaliswa kwe-benzo[a]i-pyrene-induced lung tumorigenesis kwi-A/J iimpuku.
• Inkqubela phambili yophando kwiziphumo ze-anticancer ye-vitamin K2.
• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.