Ukutya kwePapillary Stomach Adenocarcinoma!

intshayelelo

Ukutya kwePapillary Stomach Adenocarcinoma kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KwiPapillary Stomach Adenocarcinoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana nePapillary Stomach Adenocarcinoma ingaba ayinamsebenzi ukuba kukuphi ukutya endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanela umhlaza onje ngePapillary Stomach Adenocarcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno ye-Giant Butterbur ityiwa kakhulu xa ithelekiswa neWax Gourd? Ngaba kuyawenza umahluko xa kukhethwa iMango yesiqhamo kunePitanga? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neHazelnut eqhelekileyo phezu kweMacadamia Nut kunye neepulses ezifana neBroad Bean phezu kweCommon Bean. Kwaye ukuba into endiyityayo ibalulekile - ngoko umntu ukuchonga njani ukutya okucetyiswayo kwi-Papillary Stomach Adenocarcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiPapillary Stomach Adenocarcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo iMango iqulethe izithako ezisebenzayo i-Curcumin, i-Quercetin, i-Daidzein, i-Lupeol, i-Eugenol. Kwaye i-Pitanga iqulethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Quercetin, i-Daidzein, i-Lupeol kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Papillary Stomach Adenocarcinoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo se-Papillary Stomach Adenocarcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Papillary Stomach Adenocarcinoma?

Isondlo somntu somhlaza esifana nePapillary Stomach Adenocarcinoma siquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Papillary Stomach Adenocarcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana nePapillary Stomach Adenocarcinoma

Zonke ii-cancer ezifana ne-Papillary Stomach Adenocarcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Papillary Stomach Adenocarcinoma. Iindlela ze-Biochemical ezifana ne-Notch Signaling, i-MAPK Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Cell Cycle iyingxenye yenkcazo yesignesha ye-Papillary Stomach Adenocarcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Papillary Stomach Adenocarcinoma kufuneka luthathelwe ingqalelo utyikityo lweendlela zebhayomichi enxulumene nesigulana somhlaza ngamnye kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Papillary Stomach Adenocarcinoma xa uthatha unyango lomhlaza iCarboplatin, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-FN1, i-PRDM9, i-RYR3 kunye ne-MUC16 zezona ziphezulu iijene ezichazwe kwi-Papillary Stomach Adenocarcinoma. I-TP53 ixelwe kwi-45.0% yezigulane ezimele kuzo zonke iimvavanyo zekliniki. Kwaye i-FN1 ixelwe kwi-15.0%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-36 ukuya kuma-80. I-90.9 % yedatha yezigulane ichongwe njengamadoda. I-Papillary Stomach Adenocarcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela ze-biochemical kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenza isondlo somntu.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zePapillary Stomach Adenocarcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or WAX GOURD?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Eugenol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-DNA Repair kunye ne-MYC Signaling kunye nabanye. I-Giant Butterbur iyacetyiswa kwi-Papillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiCarboplatin. Oku kungenxa yokuba i-Giant Butterbur ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCarboplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Wax Gourd yi-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Eugenol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-WNT Beta Catenin Signaling kunye ne-Oxidative Stress kunye nezinye. I-Wax Gourd ayikhuthazwa kwi-Papillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo i-Carboplatin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYISINQWILI YOMFUNO INCEBISWA NGAPHEZU KWE-WAX GOURD YE-Papillary Stomach Adenocarcinoma KUNYE NONYANGO I-Carboplatin.

Khetha iSiqhamo sePITANGA okanye iMANGO?

I-Fruit Pitanga iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Quercetin, i-Daidzein, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-WNT Beta Catenin Signaling kunye ne-MYC Signaling kunye nabanye. I-Pitanga icetyiswa kwi-Papillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiCarboplatin. Oku kungenxa yokuba i-Pitanga ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCarboplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iMango yiCurcumin, Quercetin, Daidzein, Lupeol, Eugenol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. IMango ayikhuthazwa kwi-Papillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiCarboplatin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO I-PITANGA IYANCEBISWA NGAPHEZU KWE-MANGO YE-Papillary Stomach Adenocarcinoma KUNYE NONYANGO I-Carboplatin.

Khetha Nut COMMON HAZELNUT okanye MACADAMIA NUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Daidzein, i-Lupeol, i-Eugenol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Cell Cycle, i-MAPK Signaling kunye ne-Hedgehog Signaling kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kwiPapillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiCarboplatin. Oku kungenxa yokuba iHazelnut eqhelekileyo ilungisa ezo ndlela zebhayoloji ezixelwe ngokwesayensi ukuze zikhuthaze isiphumo seCarboplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Macadamia Nut yi-Curcumin, i-Apigenin, i-Daidzein, i-Lupeol, i-Eugenol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-PI3K-AKT-MTOR Ukubonakaliswa kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Macadamia Nut ayikhuthazwa kwi-Papillary Stomach Adenocarcinoma xa unyango lomhlaza oluqhubekayo yiCarboplatin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-HAZELNUT EQHELEKILEYO INCEBISIWE NGAPHEZU KWE-MACADAMIA NUT YE-Papillary Stomach Adenocarcinoma KUNYE NONYANGO I-Carboplatin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Papillary Stomach Adenocarcinoma okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha imifuno yeBRUSSEL sprouts okanye i-AMERICAN POKEWEED?

Imifuno ye-Brussel Sprouts iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Lupeol, i-Phloretin, i-Indole-3-carbinol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Cell Cycle, i-MAPK Signaling kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Brussel Sprouts yenza isincomo sengozi ye-Papillary Stomach Adenocarcinoma xa ingozi yemfuzo eyayanyaniswa nayo iyi-FN1. Oku kungenxa yokuba i-Brussel Sprouts yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yase-American Pokeweed yi-Apigenin, i-Curcumin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-American Pokeweed ayikhuthazwa xa umngcipheko we-Papillary Stomach Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-FN1 kuba yonyusa iindlela zokutyikitya kuyo.

IMIFUNO YEBRUSSEL AYICEBISIWE NGAPHEZU KWE-POKEWEED YASE-AMERICA KU-FN1 UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iFruit NANCE okanye iPUMMELO?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-P53 Signaling, i-DNA Repair kunye ne-MAPK Signaling kunye nabanye. UNance ucetyiswa kumngcipheko wePapillary Stomach Adenocarcinoma xa ingozi yemfuzo eyayanyaniswa nayo iyi-FN1. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zePummelo yi-Apigenin, i-Curcumin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition kunye ne-Extracellular Matrix Remodeling kunye nabanye. IPummelo ayikhuthazwa xa umngcipheko wePapillary Stomach Adenocarcinoma xa umngcipheko wezofuzo unxulunyaniswa noFN1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO NANCE IYACEBISWA PHEZU KWE-PUMMELO KU-FN1 GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Phloretin, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, i-Cell Cycle, i-MAPK Signaling kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Butternut icetyiswa kumngcipheko we-Papillary Stomach Adenocarcinoma xa ingozi yemfuzo eyayanyaniswa nayo iyi-FN1. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Papillary Stomach Adenocarcinoma xa umngcipheko wezofuzo uhambelana ne-FN1 kuba yonyusa iindlela zokutyikitya kuyo.

UBUTTERNUT UYCEBISWA NGAPHEZU KWE-CHESTNUT NGE-FN1 genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana nePapillary Stomach Adenocarcinoma. I-Papillary Stomach Adenocarcinoma izigulane kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana nePapillary Stomach Adenocarcinoma, nganye ineemfuza ezahlukeneyo zethumba ezinolunye ulwahlulo lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Papillary Stomach Adenocarcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

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