Ukutya kweMyelodysplastic Syndrome!

intshayelelo

Ukutya kweMyelodysplastic Syndrome kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Myelodysplastic syndromes (MDS) liqela legazi legazi elichaphazela ukuveliswa kweeseli zegazi eziqhelekileyo kumongo wethambo. Xa iseli yeleukemia engaqhelekanga isahlula, inguquko yokuqala iyagcinwa kwaye ivelise iklone yeeseli ezingaqhelekanga ezifanayo ezinesiphako esifanayo, kungoko i-MDS sisiphazamiso se-clonal blood stem cell. I-Myelodysplastic syndromes ixhaphake kakhulu kubantu abadala abangaphezu kweminyaka engama-60 kwaye ichaphazela amadoda kancinci kunabasetyhini. Kwi-MDS, iiseli ezingaqhelekanga zomongo wethambo (ezikwabizwa ngokuba zii-blasts) zivelisa amanani andayo eeseli zegazi ezingekavuthwa ezidla ngokufa phambi kwexesha. Oku kubangela amanani aphantsi eeseli ezibomvu zegazi ezikhulileyo, iiseli ezimhlophe zegazi kunye neeplatelet zenza isigulana sibe sesichengeni sosulelo, ukopha, ukugruzuka kunye nokudinwa. I-MDS ihlelwa ngokohlobo kunye nenani lokuqhuma kwi-bone marrow kwii-subtypes eziphambili ze-5: i-anemia ephikisayo; i-refractory anemia kunye ne-sideroblasts; i-anemia ephikisayo kunye nokuqhuma okugqithisileyo; i-anemia ye-refractory kunye nokuqhuma okugqithisileyo kwinguqu; kunye ne-leukemia engapheliyo ye-myelomonocytic (CMML). Abantu abane-MDS banomongo osebenzayo kodwa amanani eeseli zegazi aphantsi ngokungaqhelekanga. Iimpawu eziqhelekileyo ezinxulumene ne-MDS ziquka ukudinwa, ukuba nesiyezi, ubuthathaka, ukugruzuka nokopha, ukosuleleka rhoqo, kunye nentloko ebuhlungu. Kwezinye iimeko, i-MDS inokuqhubela phambili ekungaphumeleli kokusongela ubomi bomongo wethambo okanye ikhule ibe yi-acute myeloid leukemia (AML). Izinketho zonyango ze-myelodysplastic syndromes ziquka utofelo-gazi, izinto zokukhula ezifana ne-granulocyte-colony stimulation factor (G-CSF), i-hypomethylating agents, i-immunomodulatory agents, kunye ne-chemotherapy. Ukongezelela, ukunakekelwa kwenkxaso kunye nesondlo esifanelekileyo (ukutya kunye nezongezelelo zendalo) kunokunceda ukuphucula impilo yezigulane.

KwiMyelodysplastic Syndrome ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza kukuba - kwimihlaza efana neMyelodysplastic Syndrome ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyayo kwaye ndingakwenzi? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngeMyelodysplastic Syndrome?

Umzekelo ingaba inomsebenzi ukuba iWax Gourd yemifuno ityiwa kakhulu xa ithelekiswa neWhite Cabbage? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kuneRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/imbewu efana neHazelnut ngaphezu kweChestnut yaseYurophu kunye neepulses ezifana neAdzuki Bean phezu kweBean eluhlaza. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Myelodysplastic Syndrome kwaye ingaba impendulo efanayo kuye wonke umntu onoxilongo olufanayo okanye umngcipheko wemfuza?

Ewe! Ukutya okutyayo kubalulekile kwiMyelodysplastic Syndrome!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo Apigenin, Curcumin, Quercetin, Isoliquiritigenin, Lupeol. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Curcumin, i-Quercetin, i-Isoliquiritigenin, i-Ellagic Acid, i-Lupeol kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Myelodysplastic Syndrome - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungayihoyi ezinye. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seMyelodysplastic Syndrome.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwiMyelodysplastic Syndrome?

Izondlo zomntu zomhlaza ezifana neMyelodysplastic Syndrome ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yeMyelodysplastic Syndrome, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba semngciphekweni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMyelodysplastic Syndrome

Zonke ii-cancer ezifana ne-Myelodysplastic Syndrome zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Myelodysplastic Syndrome. Iindlela ze-Biochemical ezifana ne-Amino Acid Metabolism, i-Histone / i-Protein Acetylation, i-RUNX Signaling, i-RAS-RAF Ukubonakaliswa yinxalenye yenkcazo yesignesha ye-Myelodysplastic Syndrome. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Myelodysplastic Syndrome kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwiMyelodysplastic Syndrome xa uthatha unyango lomhlaza iLenalidomide, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-RUNX1, i-NSD1, i-JAK2, i-KMT2A kunye ne-EP300 zezona zakhi zemfuza ezixeliweyo eziphezulu ze-Myelodysplastic Syndrome. I-RUNX1 ixelwe kwi-16.1% yezigulane ezimele kuzo zonke izilingo zeklinikhi. Kwaye i-NSD1 ixelwe kwi-6.7%. I-data yezigulane ezidityanisiweyo zibandakanya iminyaka yobudala ukusuka kuma-24 ukuya kuma-86. I-58.6 % yedatha yesigulane ichongwa njengamadoda. Ibhayoloji yeMyelodysplastic Syndrome kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMyelodysplastic Syndrome

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable WAX ​​GOURD okanye IKHABHAGEJI EMHLOPHE?

Imifuno ye-Wax Gourd iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Isoliquiritigenin, i-Luteolin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Hypoxia, i-P53 Signaling kunye ne-MYC Signaling kunye nezinye. IWax Gourd yenza isincomo kwiMyelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide. Oku kungenxa yokuba i-Wax Gourd ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seLenalidomide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeKhaphetshu emhlophe yi-Curcumin, i-Quercetin, i-Isoliquiritigenin, i-Lupeol, i-Kaempferol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. Ikhaphetshu emhlophe ayikhuthazwa kwiMyelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide kuba iguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IGAMA LEWAX YOMFUNO IYAKUNIKEZISWA NGAPHEZU KWEKHABHEJI EMHLOPHE NGE-Myelodysplastic Syndrome KUNYE NONYANGO ILenalidomide.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry iqukethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Isoliquiritigenin, i-Ellagic Acid, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Hypoxia, i-P53 Signaling kunye ne-MYC Signaling kunye nezinye. I-Red Raspberry iyacetyiswa kwi-Myelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide. Oku kungenxa yokuba i-Red raspberry iguqula ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seLenalidomide.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Apigenin, i-Curcumin, i-Quercetin, i-Isoliquiritigenin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. IPummelo ayikhuthazwa kwiMyelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ESIBOMVU IRASPBHARI IYAKUCEBISWA NGAPHEZU KWE-PUMMELO YE-Myelodysplastic Syndrome KUNYE NONYANGO ILenalidomide.

Khetha Nut HAZELNUT okanye EUROPEAN CHESTNUT?

I-Hazelnut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Isoliquiritigenin, i-Luteolin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-Histone / i-Protein Acetylation, i-P53 Signaling kunye ne-Hypoxia kunye nabanye. IHazelnut icetyiswa kwiMyelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide. Oku kungenxa yokuba iHazelnut iguqula ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo seLenalidomide.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Apigenin, i-Curcumin, i-Quercetin, i-Isoliquiritigenin, i-Ellagic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Myelodysplastic Syndrome xa unyango lomhlaza oluqhubekayo yiLenalidomide kuba luguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

I-HAZELNUT IYAKUNIKEZISWA NGE-CHESTNUT YAseYurophu NGE-Myelodysplastic Syndrome KUNYE NONYANGO ILenalidomide.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuza ye-Myelodysplastic Syndrome okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable YELLOW ZUCCHINI okanye SWEDE?

I-Vegetable Yellow Zucchini iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Histone / i-Protein Acetylation, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Zucchini emthubi icetyiswa kumngcipheko we-Myelodysplastic Syndrome xa umngcipheko wemfuzo onxulumeneyo yi-EP300. Oku kungenxa yokuba iZucchini emthubi yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSweden yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye nezinye. I-Swede ayikhuthazwa xa umngcipheko we-Myelodysplastic Syndrome xa umngcipheko wezofuzo uhambelana ne-EP300 kuba yonyusa iindlela zokutyikitya kuyo.

I-ZUCCHINI YOMFUNO EYELLOW ICEBISWA NGAPHEZU KWE-SWEDE NGE-EP300 UMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iSiqhamo SOUR CHERRY okanye iJUJUBE?

I-Fruit Sour Cherry iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Histone / i-Protein Acetylation, i-PI3K-AKT-MTOR Umqondiso kunye ne-MYC Signaling kunye nabanye. I-Sour Cherry icetyiswa kumngcipheko we-Myelodysplastic Syndrome xa umngcipheko wemfuzo onxulumeneyo yi-EP300. Oku kungenxa yokuba iCherry emuncu yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeJujube yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-PI3K-AKT-MTOR yokuSayina kunye ne-Cell Cycle Checkpoints kunye nabanye. IJujube ayikhuthazwa xa umngcipheko weMyelodysplastic Syndrome xa umngcipheko wemfuzo uhambelana ne-EP300 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO SOUR CHErry KUNCEBISIWE PHEZU KWEJUJUBE EP300 GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling, i-Histone / i-Protein Acetylation, i-Cell Cycle Checkpoints kunye ne-MYC Signaling kunye nabanye. I-Butternut iyacetyiswa kumngcipheko we-Myelodysplastic Syndrome xa umngcipheko wemfuzo ohambelana ne-EP300. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Curcumin, i-Apigenin, i-Formononetin, i-Lupeol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye neCell Cycle Checkpoints kunye nezinye. I-Chestnut ayikhuthazwa xa umngcipheko we-Myelodysplastic Syndrome xa umngcipheko wemfuzo uhambelana ne-EP300 kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-CHESTNUT YE-EP300 GENETIC RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Myelodysplastic Syndrome. Izigulana ze-Myelodysplastic Syndrome kunye nabantu abasengozini yemfuza bahlala benombuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Myelodysplastic Syndrome, nganye inemfuza eyahlukileyo ye-tumor enolunye utshintsho lwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neWax Gourd kuqulethe i-bioactives eyohlukeneyo ngokwemiyinge eyahlukeneyo, enempembelelo kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela ze-biochemical. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikukhethe okanye ndingakhethi kwi-Myelodysplastic Syndrome?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

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• I-Melatonin kunye ne-vitamin D3 i-synergistically down-regulate i-Akt kunye ne-MDM2 ekhokelela kwi-TGFβ-1-exhomekeke ekukhulisweni kwe-inhibition yeeseli zomhlaza webele.
• I-In vitro kunye ne-vivo antitumor umsebenzi we-neochlorogenic acid kwiiseli ze-gastric carcinoma zesisu zincediswa kunye ne-ROS isizukulwana, ukulahlekelwa kwe-membrane ye-mitochondrial kunye ne-apoptosis induction.
• I-lipidomics esebenzayo: I-Palmitic acid iphazamisa uphuhliso lwe-hepatocellular carcinoma ngokumodareyitha ulwelo lwe-membrane kunye ne-glucose metabolism.
• https://rarediseases.org/rare-diseases/myelodysplastic-syndromes/#:~:text=General%20symptoms%20associated%20with%20MDS,or%20develop%20into%20acute%20leukemia.
• https://www.leukaemia.org.au/blood-cancer-information/types-of-blood-cancer/myelodysplastic-syndromes
• https://www.ncbi.nlm.nih.gov/books/NBK534126