Ukutya kweMetastaic Squamous Neck Cancer ngeOcult Primary!

intshayelelo

Ukutya kweMetastatic Squamous Neck Cancer kunye neOccult Primary kufuneka ilungiselelwe umntu ngamnye kwaye kufuneka ilungelelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

NgoMhlaza weNtamo weMetastatic Squamous Neck Primary ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngesondlo obubuzwa zizigulana ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza womhlaza onje ngeMetastatic Squamous Neck Cancer With Occult Primary ingaba ayinamsebenzi ukuba kukutya ntoni na endikutyayo kwaye ndingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwizityalo ngaba kwanele umhlaza onje ngeMetastatic Squamous Neck Cancer ngeOccult Primary?

Umzekelo ingaba inomsebenzi ukuba iJute yemifuno ityiwa kakhulu xa ithelekiswa neGarland Chrysanthemum? Ngaba kuyawenza umahluko ukuba iziqhamo zeStrowberry zikhethwa ngaphezu kweTamarind? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neHazelnut eqhelekileyo ngaphezu kweChestnut yaseYurophu kunye neepulses ezifana neAlfalfa phezu kweCatjang Pea. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Metastatic Squamous Neck Cancer nge-Occult Primary kwaye ngaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiMetastatic Squamous Neck Cancer kunye neOccult Primary!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo I-Strawberry iqulethe izithako ezisebenzayo i-Curcumin, i-Quercetin, i-Ellagic Acid, i-Lupeol, i-Formononetin. Kwaye iTamarind iqulethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Phloretin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo eyenziwa xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Metastatic Squamous Neck Cancer Nge-Occult Primary - kukuvavanya kuphela izithako ezisebenzayo ezikhethiweyo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Metastatic Squamous Neck Cancer nge-Occult Primary.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kwiSiseko seSondlo seMetastatic Squamous Neck Cancer ngePrayimari ye-Occult?

Izondlo zomntu zomhlaza ezifana neMetastatic Squamous Neck Cancer With Occult Primary iquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwiMetastatic Squamous Neck Cancer nge-Occult Primary biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neMetastatic Squamous Neck Cancer ngeOccult Primary

Zonke ii-cancer ezifana ne-Metastatic Squamous Neck Cancer With Occult Primary zingabonakaliswa ngesethi ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Metastatic Squamous Neck Cancer With Occult Primary. Iindlela ze-Biochemical ezifana ne-Cell Cycle Checkpoints, i-Cell Cycle, i-PI3K-AKT-MTOR Ukubonakaliswa, Ukubonakaliswa kwe-MAPK kuyingxenye yenkcazo yesignesha ye-Metastatic Squamous Neck Cancer nge-Occult Primary. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Metastatic Squamous Neck Cancer kunye ne-Occult Primary kufuneka ithathele ingqalelo utyikityo lweendlela ze-biochemical zesigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Metastatic Squamous Neck Cancer nge-Occult Primary xa uthatha unyango lomhlaza i-Dacarbazine, kunye nokutya okunye kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-COL1A1, i-COL2A1, i-CREB1 kunye ne-ETS1 zezona ziphezulu iigenes ezixeliweyo zeMetastatic Squamous Neck Cancer nge-Occult Primary. I-TP53 ixelwe kwi-55.6% yezigulane ezimele kuzo zonke izilingo zonyango. Kwaye i-COL1A1 ichazwe kwi-33.3%. Idatha yesigulana esidityanisiweyo sigubungela iminyaka ukusuka ukuya . I-% yedatha yesigulane ichongwa njengamadoda. Umhlaza weNtamo yeMetastatic Squamous Nebhayoloji yaseSiprayimari ye-Occult kunye nemfuzo exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeMetastatic Squamous Neck Cancer kunye nePrayimari ye-Occult

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable JUTE okanye iGARLAND CHRYSANTHEMUM?

I-Vegetable Jute iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Quercetin, i-Lupeol, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-NFKB yokuSayina kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Jute icetyiswa kwi-Metastatic Squamous Neck Cancer nge-Occult Primary xa unyango oluqhubekayo lomhlaza yi-Dacarbazine. Oku kungenxa yokuba i-Jute iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukwazisa umphumo we-Dacarbazine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Garland Chrysanthemum yi-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, uxinzelelo lwe-Oxidative kunye ne-TWEAK Signaling kunye nabanye. I-Garland Chrysanthemum ayikhuthazwa kwi-Metastatic Squamous Neck Cancer nge-Occult Primary xa unyango lomhlaza oluqhubekayo yi-Dacarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

IJUTE YOMFUNO KUNCEBISWA NGENXA YEGARLAND IKHRYSANTHEMUM YOMHLAZA weNtamo yeMetastatic Squamous nge-Occult Primary kunye noNyango lweDacarbazine.

Khetha iSiqhamo TAMARIND okanye STRAWBERRY?

I-Fruit Tamarind iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Formononetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ii-Checkpoints ze-Cell Cycle, i-NFKB Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Tamarind icetyiswa kwi-Metastatic Squamous Neck Cancer nge-Occult Primary xa unyango oluqhubekayo lomhlaza yi-Dacarbazine. Oku kungenxa yokuba i-Tamarind iguqula ezo ndlela ze-biochemical eziye zachazwa ngokwesayensi ukuze zikhuthaze umphumo weDacarbazine.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo ze-Strawberry yi-Curcumin, i-Quercetin, i-Ellagic Acid, i-Lupeol, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-P53 Signaling kunye ne-TWEAK Signaling kunye nabanye. I-Strawberry ayikhuthazwa kwi-Metastatic Squamous Neck Cancer Nge-Occult Primary xa unyango lomhlaza oluqhubekayo yi-Dacarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

ISIQHAMO UTAMARIND KUCEBISWA NGAPHEZU KWESTRAWBERRY YE-Metastatic Squamous Neck Cancer kunye ne-Occult Primary kunye noNyango Dacarbazine.

Khetha i-Nutt EQHELEKILEYO IHAZELNUT okanye i-EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lupeol, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, ukulungiswa kwe-DNA, i-Cell Cycle Checkpoints kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Hazelnut eqhelekileyo icetyiswa kwi-Metastatic Squamous Neck Cancer Nge-Occult Primary xa unyango oluqhubekayo lomhlaza yi-Dacarbazine. Oku kungenxa yokuba i-Hazelnut eqhelekileyo iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukuze zikhuthaze umphumo we-Dacarbazine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Curcumin, i-Apigenin, i-Quercetin, i-Ellagic Acid, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA, uxinzelelo lwe-Oxidative kunye ne-TWEAK Signaling kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Metastatic Squamous Neck Cancer Nge-Occult Primary xa unyango lomhlaza oluqhubekayo yi-Dacarbazine kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

I-HAZELNUT EQHELEKILEYO KUNCEBISWA KWI-CHESTNUT YAseYurophu ye-Metastatic Squamous Neck Cancer nge-Occult Primary kunye noNyango lweDacarbazine.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abanomngcipheko wemfuzo we-Metastatic Squamous Neck Cancer nge-Occult Primary okanye imbali yentsapho "Yintoni endimele ndiyitye ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable GIANT BUTTERBUR or SWISS CHAARD?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-MYC Signaling kunye ne-Oxidative Stress kunye nabanye. I-Giant Butterbur iyacetyiswa kumngcipheko we-Metastatic Squamous Neck Cancer Nge-Occult Primary xa ingozi yemfuzo eyayanyaniswa nayo yi-COL1A1. Oku kungenxa yokuba i-Giant Butterbur yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yaseSwitzerland Chard yi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Swiss Chard ayikhuthazwa xa umngcipheko we-Metastatic Squamous Neck Cancer nge-Occult Primary xa umngcipheko wezofuzo uhambelana ne-COL1A1 kuba yonyusa iindlela zokutyikitya.

IBHUTTERBURE EYISINXIBA YOMFUNO IYACEBISWA PHEZU KWESWISS CHAARD NGE-COL1A1 YOMNGCIPHEKO WEMFUZO YOMHLAZA.

Khetha iSiqhamo JAVA PLUM okanye i-APPLE?

Iziqhamo zeJava Plum ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Ellagic Acid, i-Lupeol, i-Daidzein. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ii-Checkpoints ze-Cell Cycle, i-Focal Adhesion kunye ne-PI3K-AKT-MTOR Signaling kunye nabanye. I-Java Plum icetyiswa kumngcipheko we-Metastatic Squamous Neck Cancer Nge-Occult Primary xa ingozi yemfuzo eyayanyaniswa nayo yi-COL1A1. Oku kungenxa yokuba iJava Plum yonyusa ezo ndlela zebhayokhemikhali ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo ze-Apple ziyi-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Apple ayikhuthazwa xa umngcipheko we-Metastatic Squamous Neck Cancer kunye ne-Occult Primary xa umngcipheko wezofuzo uhambelana ne-COL1A1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO JAVA PLUM IYANCEBISWA PHEZU KWE-APPLE YE-COL1A1 genetic RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye PISTACHIO?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-G-protein-coupled Receptor Signaling kunye ne-Oxidative Stress kunye nabanye. I-Butternut iyacetyiswa kumngcipheko we-Metastatic Squamous Neck Cancer Nge-Occult Primary xa ingozi yemfuzo eyayanyaniswa nayo yi-COL1A1. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Pistachio yi-Curcumin, i-Lupeol, i-Daidzein, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-G-protein-coupled Receptor Signaling kunye ne-Oxidative Stress kunye nezinye. I-Pistachio ayikhuthazwa xa umngcipheko we-Metastatic Squamous Neck Cancer Nge-Occult Primary xa umngcipheko wezofuzo uhambelana ne-COL1A1 kuba yonyusa iindlela zokutyikitya.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-PISTACHIO YE-COL1A1 genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Metastatic Squamous Neck Cancer kunye ne-Occult Primary. Umhlaza weMetastatic Squamous Neck Nezigulana zaseOccult Primary kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezinje ngeMetastatic Squamous Neck Cancer ngeOccult Primary, nganye ineemfuza ezahlukeneyo zethumba ezinokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neJute kuqulethe izinto ezahlukeneyo zebhayoloji kwimithamo eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo somhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza isigqibo esilula kwaye sisuse yonke into eqikelelwayo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi i-Metastatic Squamous Neck Cancer nge-Occult Primary?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

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