Ukutya kwe-Adrenocortical Carcinoma?

intshayelelo

Ukutya kwe-Adrenocortical Carcinoma kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuzo yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

I-Adrenocortical carcinoma luhlobo olunqabileyo lomhlaza oluvela kumaleko angaphandle e-adrenal glands, ebekwe phezu kwezintso. Ulwandlalo lwePathology ludlala indima ebalulekileyo ekuqondeni iimpawu kunye neempawu ze-adrenocortical carcinoma, inceda ekuxilongeni ngokuchanekileyo. Iimpawu ze-adrenocortical carcinoma zinokwahluka, kodwa zinokubandakanya intlungu yesisu, ukufumana ubunzima, ukungalingani kwehomoni kunye noxinzelelo lwegazi oluphezulu. Ubuchule beRadiology busetyenziselwa ukujonga kunye nokuvavanya i-adrenocortical carcinoma tumors. Izinga lokusinda kwi-adrenocortical carcinoma lixhomekeke kwizinto ezahlukeneyo, kubandakanywa nenqanaba lokuxilongwa. I-Metastasis, okanye ukusasazeka kwethumba kwamanye amalungu omzimba, kukuchaphazela kakhulu ukuxilonga. Ikhowudi echanekileyo usebenzisa inkqubo ye-ICD-10 iqinisekisa amaxwebhu afanelekileyo e-adrenocortical carcinoma kwiirekhodi zonyango. Unyango lwe-adrenocortical carcinoma lubandakanya indibaniselwano yotyando, ichemotherapy, kunye nonyango ekujoliswe kulo, olukhokelwa zizikhokelo zonyango. Izilingo zeklinikhi zibonelela ngamathuba okuhlola iindlela ezintsha zonyango kunye nokuphucula iziphumo kwizigulane ezine-adrenocortical carcinoma. Kwezinye iimeko, i-carcinoma ye-adrenocortical ingaba yifa, igxininisa ukubaluleka kokuhlolwa kofuzo kunye neengcebiso. Ukuqonda oonobangela kunye nemingcipheko enxulumene ne-adrenocortical carcinoma kubalulekile kuthintelo kunye nokufunyanwa kwangoko. Izehlo ze-adrenocortical carcinoma zisezantsi kakhulu, nto leyo eyenza ukuba ulawulo olubanzi kunye nokhathalelo olulodwa luyimfuneko. Kubalulekile ukuhlala unolwazi malunga nophando lwamva nje kunye nenkqubela phambili ukuze unikeze ngezona ndlela zonyango zingcono kunye nenkxaso kubantu abane-adrenocortical carcinoma.

Kwi-Adrenocortical Carcinoma ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, iindongomane, imbewu umntu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza - ngoomhlaza onje ngeAdrenocortical Carcinoma ingaba ibalulekile na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje ngeAdrenocortical Carcinoma?

Umzekelo ingaba inomsebenzi ukuba imifuno ye-Giant Butterbur ityiwa kakhulu xa ithelekiswa neMalabar Spinatshi? Ngaba kuyawenza umahluko xa kukhethwa isiqhamo seGrapefruit kunePitanga? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/imbewu efana neButternut ngaphezu kweChestnut yaseYurophu kunye neentyatyambo ezifana nePea enamehlo aMnyama phezu kweCatjang Pea. Kwaye ukuba into endiyityayo ibalulekile - umntu uchonga njani ukutya okucetyiswayo kwi-Adrenocortical Carcinoma kwaye ingaba impendulo efanayo kuye wonke umntu onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwi-Adrenocortical Carcinoma!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo, i-Grapefruit iqulethe izithako ezisebenzayo i-Curcumin, i-Isoliquiritigenin, i-Lycopene, i-Lupeol, i-Phloretin. Kwaye i-Pitanga iqulethe izithako ezisebenzayo i-Curcumin, i-Apigenin, i-Quercetin, i-Isoliquiritigenin, i-Lycopene kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa uthatha isigqibo kunye nokukhetha ukutya okutyayo kwi-Adrenocortical Carcinoma - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Kuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo ukwenza isigqibo sesondlo se-Adrenocortical Carcinoma.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kwi-Adrenocortical Carcinoma?

Izondlo zomntu zomhlaza ezifana ne-Adrenocortical Carcinoma ibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwi-Adrenocortical Carcinoma biology, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle ukuba unyango lomhlaza lusebenza njani kunye nokuba semngciphekweni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Adrenocortical Carcinoma

Zonke ii-cancer ezifana ne-Adrenocortical Carcinoma zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Adrenocortical Carcinoma. Iindlela ze-Biochemical ezifana ne-Cell Cycle, i-Nucleotide Metabolism, i-Molekyuli encinci yezoThutho, i-Focal Adhesion iyingxenye yenkcazo yesignesha ye-Adrenocortical Carcinoma. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Adrenocortical Carcinoma kufuneka luthathele ingqalelo utyikityo lweendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto okunye ukutya kunye nezongezo zicetyiswayo kwi-Adrenocortical Carcinoma xa uthatha unyango lomhlaza iCisplatin, kwaye okunye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-CTNNB1, i-MUC16, i-FAT4, i-MEN1 kunye ne-KMT2B zezona ziphezulu iijene ezixeliweyo ze-Adrenocortical Carcinoma. I-CTNNB1 ixelwe kwi-12.3% yezigulane ezimele kuzo zonke iimvavanyo zeklinikhi. Kwaye i-MUC16 inikwe ingxelo nge-12.3%. Idatha yezigulane ezidityanisiweyo zibandakanya iminyaka yobudala ukusuka ku-1 ukuya kuma-88. I-35.7 % yedatha yesigulane ichongwa njengamadoda. I-Adrenocortical Carcinoma biology kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo ze-Adrenocortical Carcinoma

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or MALABAR SPINACH?

I-Butterbur enkulu yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Isoliquiritigenin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-JAK-STAT Signaling, i-NFKB Signaling, i-Cell Cycle kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. IButterbur enkulu iyacetyiswa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo yiCisplatin. Oku kungenxa yokuba i-Giant Butterbur ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCisplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno i-Malabar Spinach yi-Curcumin, i-Apigenin, i-Quercetin, i-Isoliquiritigenin, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Epithelial ukuya kwi-Mesenchymal Transition kunye nokulungiswa kwe-DNA kunye nabanye. I-Malabar Spinatshi ayikhuthazwa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo yi-Cisplatin kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYISINXIBA YOMFUNO INCEBISWA NGAPHEZU KWE-MALABAR SPINACH NGE-Adrenocortical Carcinoma KUNYE NONYANGO I-Cisplatin.

Khetha iSiqhamo sePITANGA okanye iGRAPUPRUIT?

I-Fruit Pitanga iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Quercetin, i-Isoliquiritigenin, i-Lycopene. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-NFKB Signaling, i-Cell Cycle kunye ne-Epithelial kwi-Mesenchymal Transition kunye nabanye. I-Pitanga icetyiswa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo i-Cisplatin. Oku kungenxa yokuba i-Pitanga ilungisa ezo ndlela ze-biochemical ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo se-Cisplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeGrapefruit yi-Curcumin, i-Isoliquiritigenin, i-Lycopene, i-Lupeol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. I-Grapefruit ayikhuthazwa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo i-Cisplatin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO PITANGA IYANCEBISWA NGAPHEZU KWEGRAPEFRUIT YE-Adrenocortical Carcinoma KUNYE NONYANGO I-Cisplatin.

Khetha Nut BUTTERNUT okanye EUROPEAN CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Isoliquiritigenin, i-Lycopene, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-NFKB Signaling, i-JAK-STAT Signaling, i-Cell Cycle kunye ne-Cell Cycle Checkpoints kunye nezinye. I-Butternut iyacetyiswa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo yiCisplatin. Oku kungenxa yokuba iButternut ilungisa ezo ndlela zebhayoloji ezixelwe ngokwenzululwazi ukuze zikhuthaze isiphumo seCisplatin.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Curcumin, i-Apigenin, i-Quercetin, i-Ellagic Acid, i-Isoliquiritigenin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress, i-Epithelial ukuya kwi-Mesenchymal Transition kunye nokulungiswa kwe-DNA kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa kwi-Adrenocortical Carcinoma xa unyango lomhlaza oluqhubekayo i-Cisplatin kuba luguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-EUROPA CHESTNUT YE-Adrenocortical Carcinoma KUNYE NONYANGO I-Cisplatin.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwe ngabantu abasengozini yemfuzo ye-Adrenocortical Carcinoma okanye imbali yosapho "Yintoni endimele ndiyitye ngokwahlukileyo kunangaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable PEPPER (C. FRUTESCENS) okanye iDAIKON RADISH?

I-Pepper yemifuno (c. Frutescens) iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, ukubonakaliswa kweStem Cell, i-Epithelial kwi-Mesenchymal Transition kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Pepper (c. Frutescens) icetyiswa kumngcipheko we-Adrenocortical Carcinoma xa ingozi yemfuzo ehambelana nayo yi-CTNNB1. Oku kungenxa yokuba iPepper (c. Frutescens) yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Daikon Radish yi-Curcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling, iVithamin D yokuSawula kunye noLungiso lweDNA kunye nezinye. I-Daikon Radish ayikhuthazwa xa umngcipheko we-Adrenocortical Carcinoma xa umngcipheko wezofuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

IPEPPER YOMFUNO (C. FRUTESCENS) KUNCEBISWA NGAPHEZU KWE-DAIKON RADISH YE-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha iSiqhamo JAVA PLUM okanye PUMMELO?

Iziqhamo zeJava Plum ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana neCurcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, ukubonakaliswa kweStem Cell, i-Epithelial kwi-Mesenchymal Transition kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. I-Java Plum iyacetyiswa kumngcipheko we-Adrenocortical Carcinoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba iJava Plum yonyusa ezo ndlela zebhayokhemikhali ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Curcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Naringin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-WNT Beta Catenin Signaling kunye nokulungiswa kweDNA kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Adrenocortical Carcinoma xa umngcipheko wezofuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

ISIQHAMO JAVA PLUM IYACEBISWA PHEZU KWE-PUMMELO NGE-CTNNB1 GENETIC RISK YOMHLAZA.

Khetha Nut CHIA okanye WALNUT?

I-Chia iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-PI3K-AKT-MTOR Ukubonakaliswa, i-Epithelial ukuya kwi-Mesenchymal Transition, i-Oncogenic Cancer Epigenetics kunye ne-P53 Signaling kunye nabanye. I-Chia icetyiswa kumngcipheko we-Adrenocortical Carcinoma xa umngcipheko wemfuzo ohambelana ne-CTNNB1. Oku kungenxa yokuba i-Chia yonyusa ezo ndlela zebhayoloji ezichasana nabaqhubi abatyikityayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Walnut yi-Curcumin, i-Apigenin, i-Lupeol, i-Beta-sitosterol, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana neVithamin D Signaling kunye ne-Oncogenic Cancer Epigenetics kunye nabanye. IWalnut ayikhuthazwa xa umngcipheko we-Adrenocortical Carcinoma xa umngcipheko wemfuzo uhambelana ne-CTNNB1 kuba yonyusa iindlela zokutyikitya kuyo.

I-CHIA ICEBISIWE NGE-WALNUT NGE-CTNNB1 genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezelelo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Adrenocortical Carcinoma. Izigulana ze-Adrenocortical Carcinoma kunye nabantu abasengozini yemfuzo bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye ezingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Adrenocortical Carcinoma, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba kube lula ukwenza isigqibo kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Adrenocortical Carcinoma?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• Iipateni zeCell-of-Origin ziLawula uHlelo lweMolekyuli ye-10,000 ye-Tumors ukusuka kwiintlobo ze-33 ze-Cancer.
• Indlela yeNzululwazi eVulekileyo eScalable yokuBiza uTshintsho lweTumor exomes kusetyenziswa iiMibhobho ezininzi zeGenomic.
• Iindlela zeGenomic kunye neziSebenzayo zokuqonda iCancer Aneuploidy.
• I-Driver Fusion kunye neziphumo zabo kuPhuhliso kunye noNyango lwe-Cancer yoLuntu.
• Isixhobo esiDityanisiweyo se-TCGA yePan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.
• Iindlela zoMbonakaliso ze-Oncogenic kwi-Cancer Genome Atlas.
• Uhlalutyo lweMicrobiome lwegazi kunye nezicubu lucebisa indlela yokuxilonga umhlaza.
• Umbono kwiiNkqubo ze-Oncogenic ekupheleni kokuQala kweCancer Genomics.
• Ubume beMicrosatellite Ukungazinzi kuzo zonke iintlobo zeCancer ezingama-39.
• I-Daidzein yenza umsebenzi wokulwa ne-tumor ngokuchasene neeseli zomhlaza wesinyi ngokunqanda indlela ye-FGFR3.
• IVithamin C ibulala ngokukhetha i-KRAS kunye ne-BRAF iiseli zomhlaza eziguqukayo ze-colorectal ngokujolisa kwi-GAPDH.
• I-Retinol inciphisa amanqanaba eprotheyini ye-beta-catenin kwimigca yeseli ye-retinoic acid-resistant colon cancer.
• Iziphumo ze-isoliquiritigenin kwiiseli zomhlaza we-ovarian.
• I-Betulinic Acid iNxinzelela iMetastasis yoMhlaza wamabele ngokuJonga i-GRP78-Mediated Glycolysis kunye ne-ER Stress Apoptotic Pathway.
• I-Paederia foetida yenza umsebenzi we-anticancer ngokumodareyitha i-chromatin modification enzymes kunye nokuguqula i-pro-inflammatory cytokine gene expression kwiiseli zomhlaza we-prostate.
• I-lipidomics esebenzayo: I-Palmitic acid iphazamisa uphuhliso lwe-hepatocellular carcinoma ngokumodareyitha ulwelo lwe-membrane kunye ne-glucose metabolism.
• Ukunyanzeliswa kwe-EGF-induced tumor cell migration kunye ne-matrix metalloproteinase-9 inkcazo nge-capsaicin nge-inhibition ye-EGFR-mediated FAK / Akt, PKC / Raf / ERK, p38 MAPK, kunye ne-AP-1 yokubonisa.