Ukutya koMhlaza weHypopharyngeal!

intshayelelo

Ukutya koMhlaza weHypopharyngeal kufuneka kulungiselelwe umntu ngamnye kwaye kufuneka kuziqhelanise xa unyango lomhlaza okanye utshintsho lwemfuza yethumba. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

Umhlaza we-Hypopharyngeal unqabile, amathumba anobungozi akhula kwi-hypopharynx, eyona ndawo isezantsi yomqala, emva nje kwebhokisi yezwi (i-larynx). Ukutshaya icuba, ukuselwa kotywala kakhulu, ukuba sesichengeni kwiikhemikhali ezithile kunye ne-human papillomavirus (HPV) zizinto eziyingozi kumhlaza womqala we-hypopharyngeal. Iimpawu zomhlaza we-hypopharyngeal zibandakanya utshintsho kwilizwi lakho (linokuvakala lirhabaxa okanye lirhabaxa), iqhuma entanyeni, umqala obuhlungu ixesha elide, iingxaki zokuginya okanye iintlungu ezingachazwanga, ukukhala okanye ukugcwala ngaphakathi kwendlebe enye okanye zombini. Umhlaza we-hypopharyngeal ophezulu unokusasazeka kwi-esophagus, kwezinye iindawo ze-pharynx, i-larynx, i-thyroid gland, i-trachea (i-windpipe) okanye ezinye iindawo zomzimba ezifana nomqolo. Iinketho zonyango lomhlaza we-hypopharyngeal zingabandakanya utyando, unyango lwemitha, kunye nechemotherapy, ngokuxhomekeke kwinqanaba kunye neemeko zomntu ngamnye. Izinga lokusinda kumhlaza we-hypopharyngeal kuxhomekeke kwizinto ezahlukeneyo, kubandakanywa nenqanaba lokuxilongwa kunye nonyango oluthile olufunyenweyo. Ngokujongana nezizathu zomhlaza we-hypopharyngeal, njengokuyeka ukutshaya kunye nokunciphisa ukusetyenziswa kotywala, kunye nokutya ukutya okunokulinganisela kunye nokufanelekileyo kunye nokutya okufanelekileyo kwezityalo kunye nezongezelelo, izigulane zinokunciphisa umngcipheko wokuphindaphinda.

NgoMhlaza we-Hypopharyngeal ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza onje nge-Hypopharyngeal Cancer ingaba ibalulekile na into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekwe kwisityalo oko kwanele umhlaza onje nge-Hypopharyngeal Cancer?

Umzekelo ingaba ibalulekile na into yokuba iKhaphetshu yemifuno ityiwa kakhulu xa ithelekiswa neCeleriac? Ngaba kuyawenza umahluko ukuba isiqhamo iJackfruit siyakhethwa kuneBlack Crowberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane/iimbewu ezifana neHazelnut eqhelekileyo ngaphezu kweChestnut yaseYurophu kunye nezityalo ezifana neCowpea ngaphezu kweLima Bean. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Cancer Hypopharyngeal kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiCancer Hypopharyngeal!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Ngokomzekelo iJackfruit iqulethe izithako ezisebenzayo i-Apigenin, i-Curcumin, i-Lupeol, i-Caffeine, i-Caffeic Acid. Kwaye i-Black Crowberry iqulethe izithako ezisebenzayo i-Quercetin, i-Apigenin, i-Curcumin, i-Lupeol, i-Caffeine kwaye mhlawumbi nabanye.

Iphutha eliqhelekileyo elenziwe xa kuthathwa isigqibo kunye nokukhetha ukutya okutyayo kwi-Cancer ye-Hypopharyngeal - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo se-Hypopharyngeal Cancer.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kuMhlaza weHypopharyngeal?

Izondlo zomntu zomhlaza ezifana ne-Hypopharyngeal Cancer iquka ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubuchwephesha kwibhayoloji yoMhlaza we-Hypopharyngeal, isayensi yokutya, imfuzo, i-biochemistry kunye nokuqonda kakuhle indlela olusebenza ngayo unyango lomhlaza kunye nokuba sesichengeni okunxulumene nonyango olunokuthi luyeke ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana ne-Hypopharyngeal Cancer

Zonke i-cancer ezifana ne-Cancer Hypopharyngeal zingabonakaliswa ngesethi ekhethekileyo yeendlela ze-biochemical - iindlela zokutyikitya ze-Hypopharyngeal Cancer. Iindlela ze-Biochemical ezifana ne-Growth Factor Signaling, i-Extracellular Matrix Remodelling, i-PI3K-AKT-MTOR Ukubonakaliswa, i-Cell Cycle Checkpoints iyingxenye yenkcazo yesignesha ye-Hypopharyngeal Cancer. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kuMhlaza we-Hypopharyngeal kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayokhemikhali kwisigulana ngasinye somhlaza kunye nomntu osengozini yemfuzo. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwiCancer Hypopharyngeal xa uthatha unyango lomhlaza i-Imatinib, kunye nokutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-TP53, i-KMT2D, i-PAX5, i-PTEN kunye ne-PIK3CA zezona ziphezulu iigenes ezixeliweyo ze-Hypopharyngeal Cancer. I-TP53 ixelwe kwi-44.4% yezigulane ezimele kuzo zonke iimvavanyo zekliniki. Kwaye i-KMT2D ixelwe kwi-22.2%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-52 ukuya kuma-74. I-77.3 % yedatha yezigulane ichongwe njengamadoda. Ibhayoloji yoMhlaza we-Hypopharyngeal kunye ne-genetics exeliweyo kunye zichaza inani labantu elimele utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenza isondlo somntu.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezelelo zeCancer Hypopharyngeal

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha Ikhaphetshu yemifuno okanye iCELERIAC

Iklabishi yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Apigenin, i-Curcumin, i-Lupeol, i-Benzyl Isothiocyanate. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle, i-MYC Signaling, i-Oncogenic Cancer Epigenetics kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. Ikhaphetshu icetyiswa kwiCancer Hypopharyngeal xa unyango lomhlaza oluqhubekayo yi-Imatinib. Oku kungenxa yokuba ikhaphetshu iguqula iindlela zebhayoloji ezixelwe ngokwenzululwazi ukwazisa isiphumo se-Imatinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno yeCeleriac yiCurcumin, iLupeol, iCaffeine, iLycopene, iCaffeic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oxidative Stress kunye nezinye. I-Celeriac ayikhuthazwa kwiCancer ye-Hypopharyngeal xa unyango lomhlaza oluqhubekayo yi-Imatinib kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

IKHABHAYIJI YOMFUNO INCEBISIWE NGAPHEZU KWE-CELERIAC YE-Hypopharyngeal Cancer KUNYE NONYANGO I-Imatinib.

Khetha Isiqhamo EMNYAMA CROWBERRY okanye JACKFRUIT

Iziqhamo ezimnyama zeCrowberry ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Apigenin, i-Curcumin, i-Lupeol, i-Caffeine. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, TGFB Signaling, i-Inositol Phosphate Signaling kunye ne-Oxidative Stress kunye nabanye. I-Black Crowberry icetyiswa kwi-Cancer Hypopharyngeal xa unyango lomhlaza oluqhubekayo yi-Imatinib. Oku kungenxa yokuba iBlack Crowberry ilungisa ezo ndlela zebhayoloji eziye zaxelwa ngokwesayensi ukwazisa isiphumo se-Imatinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo zeJackfruit yi-Apigenin, i-Curcumin, i-Lupeol, i-Caffeine, i-Caffeic Acid. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oxidative Stress kunye nezinye. IJackfruit ayicetyiswa kuMhlaza weHypopharyngeal xa unyango lomhlaza oluqhubekayo yi-Imatinib kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO EMNYAMA CROWBERRY KUNCEBISWA NGAPHEZU KWE-JACKFRUIT YE-Hypopharyngeal Cancer KUNYE NONYANGO I-Imatinib.

Khetha Nut COMMON HAZELNUT okanye EUROPEAN CHESTNUT

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Curcumin, i-Lupeol, i-Caffeine, i-Lycopene. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MYC Signaling, TGFB Signaling, i-Inositol Phosphate Signaling kunye ne-Oxidative Stress kunye nabanye. I-Hazelnut eqhelekileyo icetyiswa kwi-Cancer Hypopharyngeal xa unyango oluqhubekayo lomhlaza yi-Imatinib. Oku kungenxa yokuba i-Hazelnut eqhelekileyo iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa isiphumo se-Imatinib.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Quercetin, i-Apigenin, i-Ellagic Acid, i-Curcumin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-TGFB Signaling kunye ne-Oxidative Stress kunye nezinye. I-Chestnut yaseYurophu ayikhuthazwa kwiCancer ye-Hypopharyngeal xa unyango lomhlaza oluqhubekayo yi-Imatinib kuba iguqula ezo ndlela ze-biochemical eyenza ukuba unyango lomhlaza luxhathise okanye luphendule ngaphantsi.

I-HAZELNUT EQHELEKILEYO IYANCEBISWA KWI-CHESTNUT YAseYurophu nge-Hypopharyngeal Cancer KUNYE NONYANGO I-Imatinib.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abasengozini yemfuzo ye-Hypopharyngeal Cancer okanye imbali yentsapho ithi "Yintoni endimele ndiyitye ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable WILD CARROT okanye MOUNTAIN YAM

I-Vegetable Wild Carrot iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Quercetin, i-Apigenin, i-Curcumin, i-Catechol, i-Linalool. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-MYC Signaling, i-MAPK Signaling kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Wild Carrot icetyiswa kumngcipheko we-Hypopharyngeal Cancer xa umngcipheko wemfuzo ohambelana ne-KMT2D. Oku kungenxa yokuba i-Wild Carrot yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Mountain Yam yi-Apigenin, i-Curcumin, i-Catechol, i-Myricetin, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-Insulin Signaling kunye ne-Stem Cell Signaling kunye nezinye. I-Mountain Yam ayikhuthazwa xa umngcipheko we-Cancer Hypopharyngeal xa umngcipheko wezofuzo uhambelana ne-KMT2D kuba inyusa iindlela zokutyikitya kuyo.

UMNQATHA WASEMDLA WOMFUNO UYCEBISWA PHEZU KWENTABA YAM NGEMNGCIPHEKO YEMFUZO YE-KMT2D YOMHLAZA.

Khetha iSiqhamo JAVA PLUM okanye PUMMELO

Iziqhamo zeJava Plum ziqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Ellagic Acid, i-Catechol, i-Myricetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-Insulin Signaling, i-Inositol Phosphate Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Java Plum iyacetyiswa kumngcipheko we-Hypopharyngeal Cancer xa umngcipheko wemfuzo ohambelana ne-KMT2D. Oku kungenxa yokuba iJava Plum yonyusa ezo ndlela zebhayokhemikhali ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwisiqhamo iPummelo yi-Quercetin, i-Apigenin, i-Curcumin, i-Catechol, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Cell Cycle Checkpoints, i-Insulin Signaling kunye ne-Stem Cell Signaling kunye nezinye. IPummelo ayikhuthazwa xa umngcipheko we-Cancer Hypopharyngeal xa umngcipheko wezofuzo uhambelana ne-KMT2D kuba inyusa iindlela zokutyikitya kuyo.

ISIQHAMO JAVA PLUM KUNCEBISWA NGAPHEZU KWE-PUMMELO YE-KMT2D GENETIC RISK YOMHLAZA.

Khetha Nut BUTTERNUT okanye CHESTNUT

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Apigenin, i-Curcumin, i-Catechol, i-Myricetin, i-Lupeol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Insulin Signaling, i-Inositol Phosphate Signaling kunye ne-PI3K-AKT-MTOR Umqondiso kunye nabanye. I-Butternut iyacetyiswa kumngcipheko we-Hypopharyngeal Cancer xa umngcipheko wemfuzo ohambelana ne-KMT2D. Oku kungenxa yokuba i-Butternut yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Apigenin, i-Curcumin, i-Ellagic Acid, i-Catechol, i-Myricetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Insulin Signaling, i-Stem Cell Signaling kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Chestnut ayikhuthazwa xa umngcipheko we-Cancer Hypopharyngeal xa umngcipheko wezofuzo uhambelana ne-KMT2D kuba yonyusa iindlela zokutyikitya kuyo.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-CHESTNUT YE-KMT2D genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana ne-Hypopharyngeal Cancer. Izigulana zoMhlaza we-Hypopharyngeal kunye nabantu abasengozini yemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Hypopharyngeal Cancer, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana nekhaphetshu kuqulethe izinto ezahlukeneyo zebhayoloji ngokwemiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Kukuphi ukutya endimele ndikhethe okanye ndingakhethi kwi-Cancer Hypopharyngeal?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Hnc Mskcc 2016
• I-Molecular Landscape ye-Recurrent and Metastatic Head and Neck Cancers: Iingcamango ezivela kwi-Platform yokuSekelana kwe-Oncology echanekileyo.
• I-Curcuminoids yenza i-Reactive Oxygen Species kunye ne-Autophagy yokuphucula i-Apoptosis kwiiseli zoMhlaza woMlomo woMntu.
• I-Paederia foetida yenza umsebenzi we-anticancer ngokumodareyitha i-chromatin modification enzymes kunye nokuguqula i-pro-inflammatory cytokine gene expression kwiiseli zomhlaza we-prostate.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• I-protein-tyrosine kinase inhibition: ukufunyanwa kwe-mechanism-based based agents of antitumor.
• I-Betulinic acid inqanda ukukhula komhlaza we-prostate ngokunqanda izinto ezithile ezibhaliweyo zeprotheni.
• Imiphumo ye-antitumor ye-geraniol: Ukumodareyithwa kweendlela eziphawulekayo zomhlaza (Uphononongo).
• https://my.clevelandclinic.org/health/diseases/12181-hypopharyngeal-cancer
• https://www.ncbi.nlm.nih.gov/books/NBK567720