Ukutya kweGallbladder Cancer!

intshayelelo

Ukutya for Gallbladder Umhlaza kufuneka yobuqu umntu ngamnye kwaye kufuneka kwakhona ukuziqhelanisa xa unyango umhlaza okanye ithumba utshintsho zofuzo. Ukwenziwa komntu kunye nokulungelelaniswa kufuneka kuthathelwe ingqalelo zonke izithako ezisebenzayo okanye i-bioactives equlethwe kukutya okwahlukeneyo malunga nebhayoloji yethishu yomhlaza, imfuzo, unyango, iimeko zokuphila kunye nokukhethwa kokutya. Kungoko ngexa isondlo sesinye sezigqibo ezibaluleke kakhulu kwisigulana somhlaza kunye nomntu osemngciphekweni wokuba nomhlaza – ukukhetha ukutya oza kukutya akuyondlwan’ iyanetha.

KwiGallbladder Cancer ingaba ibalulekile ukuba yeyiphi imifuno, iziqhamo, amandongomane, imbewu ayityayo?

Umbuzo oxhaphake kakhulu ngezondlo obuzwa zizigulane ezinomhlaza kunye nabantu abasengozini yomhlaza ngowomhlaza we-Gallbladder Cancer ingaba ibalulekile into yokutya endikutyayo nendingakutyiyo? Okanye ukuba ndilandela ukutya okusekelwe kwisityalo eso sanele umhlaza onjengeGallbladder Cancer?

Umzekelo ingaba iyabaluleka na into yokuba imifuno i-Giant Butterbur ityiwa kakhulu xa ithelekiswa netheniphu? Ngaba kuyawenza umahluko ukuba isiqhamo iPummelo siyathandwa kuneRed Raspberry? Kwakhona ukuba ukhetho olufanayo lwenziwa kwiindongomane / iimbewu ezifana neButternut phezu kweChestnut kunye neepulses ezifana neGram Bean phezu kweCatjang Pea. Kwaye ukuba into endiyidlayo ibalulekile - ngoko umntu uchonga njani ukutya okucetyiswayo kwi-Gallbladder Cancer kwaye ingaba impendulo efanayo kumntu wonke onokuxilongwa okufanayo okanye umngcipheko wemfuzo?

Ewe! Ukutya okutyayo kubalulekile kwiGallbladder Cancer!

Iingcebiso zokutya zisenokungafani kumntu wonke kwaye zinokwahluka nakwisifo esifanayo kunye nomngcipheko wemfuzo.

Konke ukutya (imifuno, iziqhamo, amandongomane, iimbewu, i-pulses, i-oyile njl.njl.) kunye nezongezo zesondlo zenziwe ngaphezu kwesinye isithako esisebenzayo semolekyuli okanye i-bio-actives ngokwemilinganiselo eyahlukeneyo kunye nezixa. Isithako ngasinye esisebenzayo sinendlela ekhethekileyo yokusebenza - enokuthi isebenze okanye ithintele iindlela ezahlukeneyo ze-biochemical. Ukutya okuchazwe ngokulula kunye nezongezo ezicetyiswayo zezo zingabangeli ukwanda kwabaqhubi beemolekyuli zomhlaza kodwa zibanciphise. Okanye oko kutya akufuneki kunconywe. Ukutya kuqulethe izithako ezininzi ezisebenzayo - kungoko xa uvavanya ukutya kunye nezongezelelo kufuneka uqwalasele ifuthe lazo zonke izithako ezisebenzayo ngokongezelekayo kunomntu ngamnye.

Umzekelo iPummelo iqulethe izithako ezisebenzayo iQuercetin, iCurcumin, iFormononetin, iPhloretin, iDelphinidin. Kwaye i-Red Raspberry iqulethe izithako ezisebenzayo i-Ellagic Acid, i-Quercetin, i-Curcumin, i-Formononetin, i-Phloretin kwaye mhlawumbi nabanye.

Impazamo eqhelekileyo xa kusenziwa isigqibo nokukhetha ukutya okutyayo kwi-Gallbladder Cancer - kukuvavanya kuphela izithako ezikhethiweyo ezisebenzayo eziqulethwe kukutya kwaye ungawuhoyi ukuphumla. Ngenxa yokuba izithako ezahlukeneyo ezisebenzayo eziqulethwe kukutya zinokuba neziphumo ezichasayo kubaqhubi bomhlaza - awukwazi ukukhetha i-cherry izithako ezisebenzayo ekutyeni kunye nezongezelelo zokwenza isigqibo sesondlo seGallbladder Cancer.

EWE – UKHETHO LOKUTYA LUYINGABA NOMHLAZA. IZIGQIBO ZOKUTYA KUFUNEKA IZIQWELELE ZONKE IZINTO EZISEBENZAYO ZOKUTYA.

Izakhono ezifunekayo kuMntu weSondlo kuMhlaza weGallbladder?

Izondlo zomntu ngamnye zomhlaza ezifana neGallbladder Cancer zibandakanya ukutya okucetyiswayo / izongezo; ukutya okungacetyiswanga / izongezo ezinomzekelo weeresiphi ezibeka phambili ukusetyenziswa kokutya okucetyiswayo. Umzekelo wesondlo somntu unokubonwa koku ikhonkco.

Ukugqiba ukuba kukuphi ukutya okucetyiswayo okanye okungacetyiswayo kuntsonkothile kakhulu, kufuna ubungcali kwi-Gallbladder Cancer biology, isayensi yokutya, i-genetics, i-biochemistry kunye nokuqonda kakuhle indlela unyango lomhlaza olusebenza ngayo kunye nobuthathaka obunxulumeneyo apho unyango lunokuyeka ukusebenza.

UBUCHULE OBUBONA ULWAZI OLUFUNEKAYO UKUZE SONDLWE UMNTU WOMHLAZA ZI: IBHALOJI YOMHLAZA, ISAYENSI YOKUTYA, UNYANGO LOMHLAZA KUNYE NEMFUZO.

Iimpawu zomhlaza ezifana neGallbladder Cancer

Zonke ii-cancer ezifana ne-Gallbladder Cancer zinokubonakaliswa ngoluhlu olulodwa lweendlela ze-biochemical - iindlela zokutyikitya ze-Gallbladder Cancer. Iindlela ze-Biochemical ezifana ne-Nucleotide metabolism, i-Cytokine Signaling, i-PI3K-AKT-MTOR Ukubonakaliswa, Ukubonakaliswa kwe-MAPK kuyingxenye yenkcazo yesignesha ye-Gallbladder Cancer. Imfuzo yomhlaza yomntu ngamnye inokwahluka kwaye kungoko utyikityo lwabo lomhlaza lunokwahluka.

Unyango olusebenzayo kwi-Gallbladder Cancer kufuneka luthathele ingqalelo utyikityo olunxulumene neendlela zebhayomichiyam kwisigulana somhlaza ngamnye kunye nomntu osengozini yemfuza. Ngoko ke unyango oluhlukeneyo ngeendlela ezahlukeneyo zezenzo zisebenza kakuhle kwizigulane ezahlukeneyo. Ngokufanayo kwaye ngenxa yezizathu ezifanayo ukutya kunye nezongezo kufuneka zenziwe kumntu ngamnye. Yiyo loo nto ezinye ukutya kunye nezongezo zicetyiswayo kwi-Gallbladder Cancer xa uthatha unyango lomhlaza weGemcitabine, kwaye ezinye ukutya kunye nezongezo azikhuthazwa.

Imithombo efana cBioPortal kunye nabanye abaninzi banikezela ngedatha emele isigulana esingaziwa kulingo lwezonyango kuzo zonke iimpawu zomhlaza. Le datha iqulathe iinkcukacha zophononongo lwezonyango ezifana nobungakanani besampulu / inani lezigulana, amaqela obudala, isini, ubuhlanga, unyango, indawo yethumba kunye naluphi na utshintsho lwemfuza.

I-MUC16, i-KRAS, i-CTNNB1, i-KMT2C kunye ne-APC zezona zakhi zemfuza ezixeliweyo eziphezulu zoMhlaza weGallbladder. I-MUC16 ixelwe kwi-3.6 % yezigulane ezimele kuwo onke amalingo onyango. Kwaye i-KRAS ibikwa kwi-2.4%. Idatha yezigulane ezidityanisiweyo igubungela iminyaka yobudala ukusuka kuma-37 ukuya kuma-86. I-37.5 % yedatha yezigulane ichongwe njengamadoda. Ibhayoloji yoMhlaza we-Gallbladder kunye ne-genetics exeliweyo kunye zichaza inani labantu elimelwe utyikityo lweendlela zebhayoloji kulo mhlaza. Ukuba ithumba lomhlaza lomntu ngamnye lifuzo okanye imfuza enegalelo kumngcipheko nayo iyaziwa ke leyo kufuneka isetyenziselwe ukwenziwa kwesondlo.

UKHETHO LWESONDLO MELE LUHAMBANE NOMNTU NGAMNYE WOMNTU WOMNTU.

Ukutya kunye nezongezo zeGallbladder Cancer

Kwizigulane zoMhlaza

Izigulana zomhlaza ezikunyango okanye kukhathalelo lokuthomalalisa kufuneka zenze izigqibo ngokutya kunye nezongezelelo - kwiikhalori ezifunekayo zokutya, ukulawula naziphi na iziphumo ebezingalindelekanga zonyango kunye nokuphuculwa kolawulo lomhlaza. Konke ukutya okusekelwe kwizityalo akulingani kwaye ukukhetha kunye nokubeka phambili ukutya okwenziwa ngumntu kwaye kulungiselelwe unyango oluqhubekayo lomhlaza kubalulekile kwaye kunzima. Nantsi eminye imizekelo ebonelela ngezikhokelo zokwenza izigqibo zesondlo.

Khetha iVegetable GIANT BUTTERBUR or TURNIP?

I-Vegetable Giant Butterbur iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Phloretin, i-Delphinidin, i-Catechol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-NFKB yokuSayina kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Giant Butterbur iyacetyiswa kwi-Gallbladder Cancer xa unyango lomhlaza oluqhubekayo yi-Gemcitabine. Oku kungenxa yokuba i-Giant Butterbur iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo weGemcitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Turnip yemifuno yi-Ellagic Acid, i-Quercetin, i-Curcumin, i-Formononetin, i-Phloretin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana nokulungiswa kwe-DNA kunye ne-Focal Adhesion kunye nezinye. Itheniphu ayikhuthazwa kwiGallbladder Cancer xa unyango lomhlaza oluqhubekayo yiGemcitabine kuba lulungisa ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERBURE EYISINQIZI YOMFUNO IYAKUCEBISWA NGEPHEZU KWEJIKO LOMhlaza weGallbladder KUNYE NONYANGO iGemcitabine.

Khetha iSiqhamo RED RASPBERRY okanye iPUMMELO?

Isiqhamo esiBomvu iRaspberry sinezithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Ellagic Acid, i-Quercetin, i-Curcumin, i-Formononetin, i-Phloretin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, i-Oxidative Stress, i-NFKB yokuSayina kunye ne-PI3K-AKT-MTOR yokuSayina kunye nabanye. I-Red Raspberry iyacetyiswa kwi-Gallbladder Cancer xa unyango lomhlaza oluqhubekayo yi-Gemcitabine. Oku kungenxa yokuba i-Red Raspberry iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo weGemcitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwiziqhamo iPummelo yi-Quercetin, i-Curcumin, i-Formononetin, i-Phloretin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Oxidative Stress kunye nezinye. IPummelo ayikhuthazwa kwiGallbladder Cancer xa unyango lomhlaza oluqhubekayo yiGemcitabine kuba luguqula ezo ndlela zebhayoloji ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

ISIQHAMO ERED RASPBERRY KUNCEBISWA NGAPHEZU KWE-PUMMELO YE-Gallbladder Cancer KUNYE NONYANGO iGemcitabine.

Khetha Nut BUTTERNUT okanye CHESTNUT?

I-Butternut iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Formononetin, i-Phloretin, i-Delphinidin, i-Catechol. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK yokuSayina, ukulungiswa kwe-DNA, i-Oxidative Stress kunye ne-PI3K-AKT-MTOR Ukubonakaliswa kunye nabanye. I-Butternut iyacetyiswa kwi-Gallbladder Cancer xa unyango lomhlaza oluqhubekayo yi-Gemcitabine. Oku kungenxa yokuba i-Butternut iguqula ezo ndlela ze-biochemical eziye zaxelwa ngokwesayensi ukwazisa umphumo weGemcitabine.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yi-Ellagic Acid, i-Curcumin, i-Formononetin, i-Phloretin, i-Delphinidin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Focal Adhesion kunye ne-Oxidative Stress kunye nezinye. I-Chestnut ayikhuthazwa kwi-Gallbladder Cancer xa unyango lomhlaza oluqhubekayo yi-Gemcitabine kuba luguqula ezo ndlela ze-biochemical ezenza ukuba unyango lomhlaza luxhathise okanye lungaphenduli.

IBHUTTERNUT KUCEBISWA NGAPHEZU KWE-CHESTNUT YE-Gallbladder Cancer KUNYE NONYANGO iGemcitabine.

Kubantu ngabanye abaneMngcipheko yeGenetic yoMhlaza

Umbuzo obuzwa ngabantu abanomngcipheko wemfuzo we-Gallbladder Cancer okanye imbali yentsapho "Yintoni endimele ndiyitye ngokwahlukileyo ngaphambili?" kunye nendlela ekufuneka bakhethe ngayo ukutya kunye nezongezo zokulawula imingcipheko yesi sifo. Kuba kumngcipheko womhlaza akukho nto inokwenzeka malunga nonyango - izigqibo zokutya kunye nezongezo zibalulekile kwaye yenye yezinto ezimbalwa ezinokuthi zenziwe. Konke ukutya okusekelwe kwizityalo akulingani kwaye kusekelwe kwi-genetics echongiweyo kunye nendlela yokutyikitya - ukhetho lokutya kunye nezongezelelo kufuneka lube lolwakho.

Khetha iVegetable CALABASH okanye ikhaphetshu EMNYAMA?

ICalabash yemifuno iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Phloretin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-RAS-RAF yokubonisa kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Calabash icetyiswa kumngcipheko weGallbladder Cancer xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba iCalabash yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwimifuno ye-Black Cabbage yi-Curcumin, i-Apigenin, i-Lupeol, i-Phloretin, i-Formononetin. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition, i-Stem Cell Signaling kunye ne-Oxidative Stress kunye nabanye. Ikhaphetshu emnyama ayikhuthazwa xa umngcipheko weGallbladder Cancer xa umngcipheko wofuzo unxulumene ne-APC kuba inyusa iindlela zokutyikitya.

I-CALABASH YOMFUNO KUCEBISWA NGAPHEZU KWEKHABHAGEJI EMNYAMA NGE-APC genetic RISK YOMHLAZA.

Khetha Fruit NANCE okanye EMNYAMA ELDERBERRY?

I-Fruit Nance iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Apigenin, i-Lupeol, i-Phloretin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-RAS-RAF yokubonisa kunye noxinzelelo lwe-Oxidative kunye nabanye. I-Nance icetyiswa kumngcipheko weGallbladder Cancer xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba i-Nance yonyusa ezo ndlela zebhayoloji ezichasene nabaqhubi bayo.

Ezinye zezithako ezisebenzayo okanye i-bioactives kwiziqhamo ze-Black Elderberry yi-Curcumin, i-Quercetin, i-Apigenin, i-Linalool, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition, i-Stem Cell Signaling kunye ne-Oxidative Stress kunye nabanye. Black Elderberry ayikhuthazwa xa umngcipheko Gallbladder Cancer xa umngcipheko yofuzo ezinxulumene APC kuba kwandisa iindlela utyikityo kuyo.

ISIQHAMO NANCE KUCEBISWA PHEZULU EMNYAMA ELDERBERRY FOR APC genetic RISK OF CANCER.

Khetha Nut COMMON HAZELNUT okanye EUROPEAN CHESTNUT?

I-Hazelnut eqhelekileyo iqulethe izithako ezininzi ezisebenzayo okanye i-bioactives efana ne-Curcumin, i-Quercetin, i-Lupeol, i-Phloretin, i-Formononetin. Ezi zithako ezisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-MAPK Signaling, i-PI3K-AKT-MTOR yokuSayina, i-RAS-RAF yokubonisa kunye noxinzelelo lwe-Oxidative kunye nabanye. IHazelnut eqhelekileyo iyacetyiswa kumngcipheko weGallbladder Cancer xa umngcipheko wemfuzo ohambelana ne-APC. Oku kungenxa yokuba iHazelnut eqhelekileyo yonyusa ezo pathways biochemical ezichasa utyikityo lwabaqhubi bayo.

Ezinye zezinto ezisebenzayo okanye i-bioactives kwi-Chestnut yaseYurophu yi-Curcumin, i-Quercetin, i-Apigenin, i-Ellagic Acid, i-Lupeol. Ezi zithako zisebenzayo zilawula iindlela ezahlukeneyo ze-biochemical ezifana ne-Epithelial ukuya kwi-Mesenchymal Transition, i-Stem Cell Signaling kunye ne-Oxidative Stress kunye nabanye. I-Chestnut yaseYurophu ayikhuthazwa xa umngcipheko weGallbladder Cancer xa umngcipheko wezofuzo uhambelana ne-APC kuba inyusa iindlela zokutyikitya kuyo.

I-HAZELNUT EQHELEKILEYO IYAKUNIKEZISWA NGAPHEZU KWE-EUROPEY CHESTNUT YE-APC genetic RISK YOMHLAZA.

Ukuququmbela

Ukutya kunye nezongezo ezikhethiweyo zizigqibo ezibalulekileyo zomhlaza ezifana neGallbladder Cancer. Izigulana zomhlaza we-Gallbladder kunye nabantu abanomngcipheko wemfuza bahlala benalo mbuzo: "Kukuphi ukutya kunye nezongezo zesondlo ezicetyiswayo kum kwaye zingekho?" Kukho inkolelo eqhelekileyo eyingcamango ephosakeleyo yokuba konke ukutya okusekelwe kwizityalo kunokuba luncedo okanye akunjalo kodwa akuyi kuba yingozi. Ukutya okuthile kunye nezongezelelo zinokuphazamisana nonyango lomhlaza okanye zikhuthaze abaqhubi beendlela zeemolekyuli zomhlaza.

Kukho iintlobo ezahlukeneyo zezalathisi zomhlaza ezifana ne-Gallbladder Cancer, nganye ine-tumor genetics eyahlukeneyo kunye nokwahluka kwe-genomic ngakumbi kumntu ngamnye. Ngaphaya koko, lonke unyango lomhlaza kunye nechemotherapy linendlela eyodwa yokusebenza. Ukutya ngakunye okufana neGiant Butterbur kuqulethe izinto ezahlukeneyo zebhayoloji kwimiyinge eyahlukeneyo, enefuthe kwiiseti ezahlukeneyo kunye nezahlukileyo zeendlela zebhayoloji. Inkcazo yesondlo somntu siqu zingcebiso zokutya zomntu ngamnye kwisalathiso somhlaza, unyango, imfuzo, indlela yokuphila kunye nezinye izinto. Izigqibo zokwenziwa kwesondlo kumhlaza zifuna ulwazi lwebhayoloji yomhlaza, isayensi yokutya kunye nokuqonda iindlela ezahlukeneyo zonyango lwechemotherapy. Ekugqibeleni xa kukho utshintsho lonyango okanye i-genomics entsha ichongiwe - isondlo somntu sidinga ukuphononongwa kwakhona.

Isisombululo somntu we-addon wesondlo senza ukuba isigqibo sibe lula kwaye sisuse yonke ingqikelelo ekuphenduleni umbuzo othi, "Yintoni ukutya endimele ndiyikhethe okanye ndingakhethi kwi-Gallbladder Cancer?". Iqela le-addon multi-disciplinary libandakanya oogqirha bomhlaza, izazinzulu zeklinikhi, iinjineli zesoftware kunye nososayensi bedatha.

Ucaphulo

• Msk Impact 2017
• I-TRK Fusion ityetyiswe kwiiCancer kunye ne-Histologies engaqhelekanga kunye nokungabikho kokuguqulwa kweCanonical Driver.
• Iziphumo kunye nokubaluleka kwe-formononetin kumanqanaba okubonakaliswa kwe-HIF-1α kunye ne-VEGF kwizicubu zomhlaza womlomo wesibeleko.
• Iziphumo zokuthintela i-butyric acid, i-nicotinamide, i-calcium glucarate yodwa okanye idibene ngexesha le-7, i-12-dimethylbenz (a) i-anthracene ibangele i-tumorigenesis yesikhumba semouse ngokumodareyitha kwe-K-Ras-PI3K-AKTpathway kunye ne-RNAs ezincinci ezinxulumene nazo.
• Ulawulo olubi lwe-transducer yesignali kunye ne-activator ye-transcription-3 yokubonisa i-cascade yi-lupeol inqanda ukukhula kwaye yenza i-apoptosis kwiiseli ze-hepatocellular carcinoma.