Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Osha Root lijong tsa bona?

Lintlha-khōlō Tsa

Osha Root e tsebahala haholo ka melemo ea eona ea bophelo bo botle mme e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Osha Root bakeng sa bakuli ba mofets'e li itšetlehile ka lintlha tse ngata joalo ka sesupo sa mofets'e, chemotherapy, kalafo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Mohlala, Osha Root e ka tsoela ba nang le Melanoma ea Mathomo ea Dabrafenib molemo, empa e kanna ea se be molemo ho bakuli ba fumanang Radiation bakeng sa Primary Adamantinoma. Ho feta moo, le hoja Osha Root e ka thusa batho ba nang le lefutso la "ALK", e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea lefutso "KMT2D". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Osha Root bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa tse kang mofuta oa mofetše, mekhoa ea phekolo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Osha Root ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / li-supplement tse kang Osha Root ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Osha Root lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho ja Osha Root haeba u na le liphatsa tsa lefutso tse amanang le mofetše oa ALK? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la KMT2D? Na ho molemo ho kenyelletsa Osha Root lijong tsa hau haeba u fumanoa u e-na le Primary Adamantinoma, kapa haeba tlhahlobo ea hau e le Primary Melanoma? Ho feta moo, tšebeliso ea hau ea Osha Root e lokela ho fetoloa joang haeba u ntse u fuoa kalafo ea Dabrafenib kapa morero oa hau oa phekolo o tloha Dabrafenib ho ea ho Radiation? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Motso oa Osha ke oa tlhaho, kahoo ho molemo ka linako tsohle' kapa 'Osha Root e matlafatsa sesole sa' mele' ha li lekane bakeng sa khetho ea lijo/tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ho kenyelletsa Osha Root lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Osha Root lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka liphello tse akaretsang tsa lik'hemik'hale tsa metsoako eohle, u nahane ka lintlha tse kang mofuta oa kankere, phekolo e khethehileng eo u ntseng u e etsa, liphatsa tsa lefutso. maemo a pele, le khetho ea mokhoa oa bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, joalo ka Primary Melanoma kapa Primary Adamantinoma, maano a kalafo a hloka ho hlophisoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le bong.

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofets'e ha u etsa qeto ea khetho ea lijo, joalo ka Osha Root. Na kotsi ea lefutso bakeng sa mofets'e e bakoang ke phetoho ho ALK e na le litlamorao tse ts'oanang tsa tsela ea biochemical joalo ka phetoho ho KMT2D? Ho latela pono ea phepo e nepahetseng, na kotsi e amanang le Primary Melanoma e lekana le Primary Adamantinoma? Ho feta moo, na tlhokomeliso ea lijo e lula e tšoana ho ba nang le Radiation joalo ka ba amohelang Dabrafenib? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Osha Root - Tlatsetso ea Phepo

Tlatsetso ea Osha Root e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyeletsoa Ligustilide, e 'ngoe le e' ngoe e teng ka maemo a fapaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo Cell Junctions, Oxidative Stress, Small Molecule Transport le NFKB Signaling, e laolang likarolo tse mahlonoko tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea likokoana-hloko, ho khetha li-supplement tse nepahetseng tse kang Osha Root, e le 'ngoe kapa e kopane, e fetoha qeto e boima tabeng ea phepo ea mofets'e. Ha u nahana ho sebelisa Osha Root bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Osha Root ha se qeto e akaretsang e loketseng mofets'e kaofela empa e hloka ho etsoa motho ka mong.

Ho Khetha Lisebelisoa tsa Motso oa Osha

Ho araba potso e reng 'Ke lokela ho qoba Osha Root neng maemong a Kankere' ho thata hobane karabo e itšetlehile haholo ka motho ka mong - e mpa feela e le 'Ho itšetlehile!'. Hoa tšoana le kamoo kalafo efe kapa efe ea mofetše e kanna ea se sebetse hantle ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Osha Root e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le lintho tse ling tse amanang le ho kula kaofela li phetha karolo ea ho tseba hore na Osha Root e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqetong tse joalo.

1. Na Osha Root Supplements e tla thusa bakuli ba mantlha ba Adamantinoma ba ntseng ba le kalafo ea Radiation?

Adamantinoma ea mantlha e tšoauoa ka liphetoho tse itseng tsa liphatsa tsa lefutso, e leng ARHGAP45, PI4KB le SDSL, e lebisang phetohong ea litsela tsa biochemical, haholo-holo Oxidative Stress le Inositol Phosphate Signaling. Katleho ea kalafo ea mofetše, joalo ka Radiation, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Ka mohlala, tlatsetso ea Osha Root, e amang Khatello ea Oxidative, e ka 'na ea se ke ea e-ba khetho e nepahetseng tabeng ea Primary Adamantinoma ha e etsoa ke Radiation. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Osha Root Supplements e tla thusa Bakuli ba Pele ba Melanoma ba ntseng ba etsoa ka Kalafo ea Dabrafenib?

Primary Melanoma e khetholloa ka liphetoho tse itseng tsa lefutso, tse kang TTN, MUC16 le DNAH5, tse hlahisang liphetoho litseleng tsa lik'hemik'hale tsa biochemical, haholo-holo Cell Junctions le Post Translation Modification. Ho sebetsa hantle ha kalafo ea mofets'e, joalo ka Dabrafenib, ho khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Osha Root ke khetho e utloahalang bakeng sa ba nang le Melanoma ea Mathomo ba tlas'a Dabrafenib. Sena ke hobane Osha Root e susumetsa litsela tse kang Cell Junctions, tse ka thibelang mabaka a khanna Primary Melanoma kapa tsa ruisa katleho ea Dabrafenib.

3. Na Osha Root Supplements e Sireletsehile ho Batho ba Phelang ba nang le KMT2D Mutation Associated Genetic Risk?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa KMT2D hangata o kenyelelitsoe liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea mofuta oa KMT2D e ama litsela kapa mekhoa ea lik'hemik'hale, tse kang Small Molecule Transport le Oncogenic Histone Methylation, tse amehang ka ho toba kapa ka tsela e sa tobang ho khanna kankere boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho KMT2D e amanang le kotsi e eketsehileng ea Bladder Urothelial Carcinoma, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea Osha Root ea tlatsetso. Sena ke hobane tlatsetso ea Osha Root e susumetsa litsela tse kang Small Molecule Transport, e ka lebisang litlamorao tse mpe molemong oa phetoho ea KMT2D le maemo a amanang le mofetše.

4. Na Osha Root Supplements e Sireletsehile ho Batho ba Phelang ba nang le ALK Mutation Associated Genetic Risk?

ALK e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofets'e. Liphetoho tsa ALK li ka sitisa litsela tsa bohlokoa tsa biochemical, ho kenyelletsa le NFKB Signaling le Growth Factor Signaling, tse susumetsang nts'etsopele ea mofetše. Haeba phanele ea hau ea liphatsa tsa lefutso e senola liphetoho ho ALK tse amanang le Central Nervous System, nahana ka ho kenyelletsa Osha Root supplements moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa hantle litsela tse kang NFKB Signaling, ho rua molemo ka ho fana ka tšehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa ALK le mathata a amanang le bophelo bo botle.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Osha Root, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• Karolo ea KEAP1/NRF2 le TP53 Liphetoho ho Lung Squamous Cell Carcinoma Development le Radiation Resistance.
• cBioPortal bakeng sa Cancer Genomics
• cBioPortal bakeng sa Cancer Genomics
• Moetso o kopaneng oa limolek'hule le oa bongaka oa liphetho tsa kliniki ho thibelo ea PD1 ho bakuli ba nang le melanoma ea metastatic.
• Ligustilide e thibela polelo ea iNOS e hlahisitsoeng ke LPS ho RAW 264.7 macrophages ka ho thibela tlhahiso ea ROS le ho theola taolo ea MAPK, NF-κB le AP-1 litsela tsa lipontšo.
• Bohlokoa ba tsela e nyane ea GTPase Rac1 mekhoeng ea ho hanyetsa lithethefatsi le seea-le-moea: Menyetla ea kalafo ea mofets'e.
• Tlhahlobo ea kankere ea kankere ea liphatsa tsa lefutso tse feletseng.
• Liphello tsa Ligusticum porteri (Osha) Root Extract on Human Promyelocytic Leukemia Cells.
• Phello ea Z-Ligustilide ho Tsamaea ha Lisele tsa Glioblastoma T98G tsa Motho.