Lintlha-khōlō Tsa
Horse Chestnut e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Horse Chestnut bakeng sa bakuli ba mofetše li ipapisitse le lintlha tse ngata joalo ka sesupo sa mofetše, chemotherapy, liphekolo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.
Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Horse Chestnut e ka thusa ba nang le Primary Mucosal Melanoma ea Urethra ba ntseng ba feta Doxorubicin, empa ho ka 'na ha se ke ha e-ba molemo ho bakuli ba fumanang Radiation for Primary Sclerosing Epithelioid Fibrosarcoma. Ho feta moo, le hoja Horse Chestnut e ka thusa batho ba nang le "CDH1" ea lefutso, e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea liphatsa tsa lefutso "ASXL1". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.
Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Horse Chestnut bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa joalo ka mofuta oa mofetše, mekhoa ea kalafo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Horse Chestnut ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholo-holo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.
Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / lisebelisoa tse kang Horse Chestnut ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.
Kakaretso e Khutšoanyane
Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.
Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.
Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Horse Chestnut lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho ja Horse Chestnut haeba u na le liphatsa tsa lefutso tse amanang le mofetše o amanang le CDH1? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea liphatsa tsa lefutso e bakoa ke lefutso la ASXL1? Na ho molemo ho kenyelletsa Horse Chestnut lijong tsa hau haeba u fumanoa u e-na le Primary Sclerosing Epithelioid Fibrosarcoma, kapa haeba tlhahlobo ea hau ke Primary Mucosal Melanoma ea Urethra? Ho feta moo, tšebeliso ea hau ea Horse Chestnut e lokela ho fetoloa joang haeba u ntse u le kalafo ea Doxorubicin kapa morero oa hau oa kalafo o tloha ho Doxorubicin ho ea ho Radiation? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Horse Chestnut ke tsa tlhaho, ka hona li molemo kamehla' kapa 'Horse Chestnut e matlafatsa sesole sa' mele' ha li lekane bakeng sa khetho ea lijo/tlatsetso.
Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Horse Chestnut lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka kakaretso, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Horse Chestnut lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka litlamorao tse akaretsang tsa biochemical ea lisebelisoa tsohle, u nahane ka lintlha tse kang mofuta oa mofets'e, kalafo e khethehileng eo u ntseng u e etsa, liphatsa tsa lefutso. maemo a pele, le khetho ea mokhoa oa bophelo.
Cancer
Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.
Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa kankere, o kang Primary Mucosal Melanoma ea Urethra kapa Primary Sclerosing Epithelioid Fibrosarcoma, mekhoa ea phekolo e lokela ho etsoa ho latela liphatsa tsa lefutso tsa hlahala, mohato oa lefu lena, hammoho le lintlha tse kang lilemo le bong. .”
Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.
Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofetše ha u etsa qeto ea khetho ea lijo, joalo ka Horse Chestnut. Na kotsi ea liphatsa tsa lefutso bakeng sa mofets'e e bakoang ke phetoho ho CDH1 e na le litlamorao tse ts'oanang tsa biochemical tseleng ea phetoho ho ASXL1? Ho latela pono ea phepo e nepahetseng, na kotsi e amanang le Primary Mucosal Melanoma ea Urethra e lekana le Primary Sclerosing Epithelioid Fibrosarcoma? Ho feta moo, na tlhokomeliso ea lijo e lula e tšoana ho ba nang le Radiation joalo ka ba amohelang Doxorubicin? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.
Horse Chestnut - Tlatsetso ea Phepo
Horse Chestnut ea tlatsetso e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyelletsa Esculin le Aescin, e 'ngoe le e' ngoe e teng ka maemo a fapaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo Cell Cycle Checkpoints, TGFB Signaling le Inflammation, e laolang likarolo tsa bohlokoa tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea likokoana-hloko, ho khetha li-supplement tse loketseng tse kang Horse Chestnut, e le 'ngoe kapa e kopane, e fetoha qeto ea bohlokoa tabeng ea phepo ea mofetše. Ha u nahana ho sebelisa Horse Chestnut bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Horse Chestnut ha se qeto e akaretsang e loketseng mefetše eohle empa e hloka ho etsoa motho ka mong.
Ho Khetha Lisebelisoa tsa Chestnut ea Horse
Ho araba potso e reng 'Ke lokela ho qoba Horse Chestnut neng maemong a Kankere' ho thata hobane karabo e itšetlehile haholo ka motho ka mong - e mpa feela e le 'Ho itšetlehile!'. Hoa tšoana le kamoo kalafo efe kapa efe ea mofetše e kanna ea se sebetse hantle ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Horse Chestnut e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le ho kula hofe kapa hofe ho bapala karolo ea ho tseba hore na Horse Chestnut e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqetong tse joalo.
Lijo Tseo U ka li Jang Kamora Ho Khetholla Kankere!
Ha ho kankere tse peli tse tšoanang. Fetela ka n the'ane ho tataiso e tloaelehileng ea phepo bakeng sa motho e mong le e mong 'me u etse liqeto tse ikhethileng mabapi le lijo le li-supplement ka kholiseho.
1. Na Li-Horse Chestnut Supplements li tla thusa bakuli ba Primary Sclerosing Epithelioid Fibrosarcoma ba ntseng ba etsoa kalafo ea Radiation?
Primary Sclerosing Epithelioid Fibrosarcoma e tšoauoa ka liphetoho tse itseng tsa lefutso, e leng PBRM1, ATRX le PIK3C2G, tse lebisang phetohong ea litsela tsa biochemical, haholo-holo TGFB Signaling le Inositol Phosphate Signaling. Katleho ea kalafo ea mofetše, joalo ka Radiation, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Ka mohlala, tlatsetso ea Horse Chestnut, e amang TGFB Signaling, e ka 'na ea se ke ea e-ba khetho e nepahetseng tabeng ea Primary Sclerosing Epithelioid Fibrosarcoma ha e etsoa ke Radiation. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.
2. Na Li-Supplement tsa Horse Chestnut li tla thusa Primary Mucosal Melanoma ea Urethra Bakuli ba ntseng ba etsoa kalafo ea Doxorubicin?
Primary Mucosal Melanoma ea Urethra e khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang TP53, SMARCA4 le FAT1, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo Cell Cycle Checkpoints, Apoptosis, Androgen Signaling le Chromatin Remodeling. Ho sebetsa hantle ha kalafo ea mofets'e, joalo ka Doxorubicin, ho khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Horse Chestnut ke khetho e utloahalang bakeng sa ba nang le Primary Mucosal Melanoma ea Urethra ba nang le Doxorubicin. Lebaka ke hobane Horse Chestnut e susumetsa litsela tse kang Cell Cycle Checkpoints, tse ka thibelang mabaka a tsamaisang Primary Mucosal Melanoma ea Urethra kapa tsa ruisa katleho ea Doxorubicin.
3. Na Li-Supplement tsa Horse Chestnut li bolokehile bakeng sa batho ba phelang hantle ba nang le ASXL1 Mutation Associated Genetic Risk?
Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ASXL1 hangata o kenyeletsoa liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.
Phetoho ea liphatsa tsa lefutso tsa ASXL1 e ama litsela kapa mekhoa ea lik'hemik'hale, tse kang Inflammation, Oncogenic Cancer Epigenetics le Suppressive Histone Methylation, tse amehang ka ho toba kapa ka tsela e sa tobang ho khanna kankere boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho ASXL1 e amanang le kotsi e eketsehileng ea Chronic Myelomonocytic Leukemia, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tlatsetso ea Horse Chestnut. Lebaka ke hobane tlatsetso ea Horse Chestnut e susumetsa litsela tse kang Ho ruruha, tse ka lebisang litlamorao tse mpe molemong oa phetoho ea ASXL1 le maemo a amanang le mofets'e.
4. Na Li-Supplement tsa Horse Chestnut li bolokehile bakeng sa batho ba phelang hantle ba nang le CDH1 Mutation Associated Genetic Risk?
CDH1 e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofetše. Liphetoho tsa CDH1 li ka sitisa litsela tsa bohlokoa tsa lik'hemik'hale, ho kenyelletsa le Cell Cycle Checkpoints, Adherens junction le Epithelial to Mesenchymal Transition, tse susumetsang nts'etsopele ea mofetše. Haeba phanele ea hau ea lefutso e senola liphetoho tsa CDH1 tse amanang le Kankere ea Gastric, nahana ka ho kenyelletsa li-supplement tsa Horse Chestnut moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa ka tsela e nepahetseng litsela tse kang Cell Cycle Checkpoints, ho rua molemo ka ho fana ka tšehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa CDH1 le mathata a amanang le bophelo bo botle.
Ha re phethela
Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Horse Chestnut, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.
“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.
Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.
Phepo e ikhethileng bakeng sa Kankere!
Kankere e fetoha ha nako e ntse e ea. Iketsetse 'me u fetole phepo ea hau ho latela sesupo sa mofets'e, kalafo, mokhoa oa bophelo, khetho ea lijo, lintho tse allergy le lintlha tse ling.
References
- Ho hanana le lisele tsa p53 tse kokotang ho doxorubicin ho amana le ho fokotseha ha sebopeho sa likheo tsa DNA strand ho fapana le ho senyeha ha pontšo ea apoptotic.
- cBioPortal bakeng sa Cancer Genomics
- Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.
- Ho hanyetsa seea-le-moea liseleng tsa mofetše oa matsoele ho fetisoa ka pontšo ea TGF-β, hybrid epithelial-mesenchymal phenotype le lisele tsa kankere.