Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa tee e tala lijong tsa bona?

Lintlha-khōlō Tsa

Tee e tala e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Tee e Tala bakeng sa bakuli ba mofets'e e ipapisitse le lintlha tse ngata joalo ka sesupo sa mofetše, chemotherapy, liphekolo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Tee e Tala e ka tsoela ba nang le Tumor ea Primary Solitary Fibrous Tumor ba tšoaroang ke Avastin, empa e ka 'na ea se ke ea thusa bakuli ba fumanang Radiation bakeng sa Primary Sinonasal Adenocarcinoma. Ho feta moo, le hoja Tea e Tala e ka thusa batho ba nang le "CDH1" ea lefutso, e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea lefutso "ERBB2". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Tee e Tala bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa joalo ka mofuta oa mofetše, mekhoa ea kalafo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Tee e Tala ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / li-supplement tse kang Green Tea ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa tee e tala lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho ja Tea e Tala haeba u na le liphatsa tsa lefutso tse amanang le mofetše oa CDH1? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la ERBB2? Na ho molemo ho kenyelletsa Tee e Tala lijong tsa hau haeba u fumanoa u e-na le Primary Sinonasal Adenocarcinoma, kapa haeba tlhahlobo ea hau e le Primary Solitary Fibrous Tumor? Ho feta moo, tšebeliso ea hau ea Tee e Tala e lokela ho fetoloa joang haeba u ntse u le kalafo ea Avastin kapa haeba moralo oa hau oa kalafo o tloha ho Avastin ho ea ho Radiation? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Tee e Tala ke ea tlhaho, kahoo e lula e le molemo' kapa 'Tee e Tala e matlafatsa tšireletso ea' mele ea 'mele' ha e lekane bakeng sa khetho ea lijo / tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Tee e Tala lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka kakaretso, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement joalo ka Tee e Tala lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka litlamorao tse akaretsang tsa biochemical ea lisebelisoa tsohle, ho nahanoa ka lintlha tse kang mofuta oa mofets'e, kalafo e khethehileng eo u ntseng u e fuoa, liphatsa tsa lefutso. maemo a pele, le khetho ea mokhoa oa bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, o kang Primary Solitary Fibrous Tumor kapa Primary Sinonasal Adenocarcinoma, mekhoa ea phekolo e lokela ho hlophisoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le bong.”

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofets'e ha u etsa qeto mabapi le khetho ea lijo, joalo ka Tee e Tala. Na kotsi ea liphatsa tsa lefutso bakeng sa mofetše e bakoang ke phetoho ho CDH1 e na le mekhoa e tšoanang ea lik'hemik'hale tsa biochemical joaloka phetoho ho ERBB2? Ho ea ka pono ea phepo e nepahetseng, na kotsi e amanang le Primary Solitary Fibrous Tumor e lekana le Primary Sinonasal Adenocarcinoma? Ho feta moo, na tlhokomelo ea lijo e lula e tšoana bakeng sa ba nang le Radiation le ba amohelang Avastin? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Tee e Tala - Ke Tlatsetso ea Phepo

Tlatsetso ea Tea e Tala e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho akarelletsa Geraniin, Epigallocatechin Gallate, Epicatechin Gallate, Rutin le Epigallocatechin 3- (3-methylgallate), e 'ngoe le e' ngoe e teng ka mefuta e sa tšoaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo MYC Signaling, Notch Signaling, PI3K-AKT-MTOR Signaling le Oncogenic Histone Methylation, e laolang likarolo tse mahlonoko tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea tlhaho, ho khetha li-supplement tse loketseng joalo ka Tee e Tala, e le 'ngoe kapa e kopane, e fetoha qeto ea bohlokoa maemong a phepo e nepahetseng ea mofets'e. Ha u nahana ho sebelisa Green Tea bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Tee e Tala ha se qeto e akaretsang e loketseng batho bohle ba mofets'e empa e hloka ho etsoa motho ka mong.

Ho Khetha Lisebelisoa tsa Tee e Tala

Ho araba potso e reng 'Ke lokela ho qoba Tee e Tala neng maemong a Kankere' ho thata hobane karabo ke ea motho ka mong - e mpa feela e le 'Ho ipapisitse le!'. Joalo ka ha kalafo efe kapa efe ea mofetše e kanna ea se sebetse ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Tee e Tala e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le lintho tse ling tse amanang le ho kula kaofela li phetha karolo ea ho tseba hore na Tee e Tala e loketse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqetong tse joalo.

1. Na Li-Supplement tsa Tee e Tala li tla thusa bakuli ba Primary Sinonasal Adenocarcinoma ba ntseng ba etsoa kalafo ea Radiation?

Primary Sinonasal Adenocarcinoma e tšoauoa ka liphetoho tse itseng tsa liphatsa tsa lefutso, e leng ATRX, NOTCH1 le PTPRD, tse lebisang ho liphetoho litseleng tsa biochemical, haholo-holo Notch Signaling le RUNX Signaling. Katleho ea kalafo ea mofetše, joalo ka Radiation, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Mohlala, tlatsetso ea Tee e Tala, e amang Letšoao la Notch, e kanna ea se be khetho e nepahetseng tabeng ea Primary Sinonasal Adenocarcinoma ha e etsoa ke Radiation. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Li-Supplement tsa Tee e Tala li tla thusa bakuli ba mantlha ba "Solitary Fibrous Tumor" ba ntseng ba le kalafo ea Avastin?

Sehlahala sa Mantlha sa Bonosi sa Fibrous se khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang BRD4, FLI1 le KMT2C, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation le Amino Acid Metabolism. Katleho ea kalafo ea mofets'e, joalo ka Avastin, e khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena li lokela ho nahanoa. Ka mohlala, tlatsetso ea Tee e Tala ke khetho e utloahalang bakeng sa ba nang le Primary Solitary Fibrous Tumor ba nang le Avastin. Lebaka ke hobane Tee e Tala e susumetsa litsela tse joalo ka MYC Signaling, e ka thibelang mabaka a khannang Primary Solitary Fibrous Tumor kapa ea thusa katleho ea Avastin.

3. Na Li-Supplement tsa Tee e Tala li bolokehile ho batho ba phelang hantle ba nang le ERBB2 Mutation Associated Genetic Risk?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ERBB2 hangata o kenyelelitsoe liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea liphatsa tsa lefutso tsa ERBB2 e ama litsela kapa mekhoa ea lik'hemik'hale, tse kang Growth Factor Signaling le PI3K-AKT-MTOR Signaling, tse amehang ka ho toba kapa ka tsela e sa tobang ho khanna kankere boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho ERBB2 e amanang le kotsi e eketsehileng ea Esophageal Adenocarcinoma, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tee e tala e tlatselletsang. Lebaka ke hobane tlatsetso ea Tea e Tala e susumetsa litsela tse kang PI3K-AKT-MTOR Signaling, e ka lebisang liphellong tse mpe molemong oa phetoho ea ERBB2 le maemo a amanang le kankere.

4. Na Li-Supplement tsa Tee e Tala li bolokehile ho batho ba phelang hantle ba nang le CDH1 Mutation Associated Genetic Risk?

CDH1 e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofetše. Liphetoho tsa CDH1 li ka sitisa litsela tsa bohlokoa tsa biochemical, ho kenyelletsa le Oncogenic Histone Methylation, Adherens junction le Epithelial to Mesenchymal Transition, e susumetsang nts'etsopele ea mofetše. Haeba phanele ea hau ea liphatsa tsa lefutso e senola liphetoho tsa CDH1 tse amanang le Kankere ea Gastric, nahana ka ho kenyelletsa li-supplement tsa Tee e Tala moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa hantle litsela tse kang Oncogenic Histone Methylation, molemo ka ho fana ka ts'ehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa CDH1 le mathata a amanang le bophelo bo botle.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Green Tea, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• cBioPortal bakeng sa Cancer Genomics
• Khatello ea ts'ebetso ea lipopolysaccharide-induced nuclear factor-kappaB ke theaflavin-3,3'-digallate ho tloha tee e ntšo le li-polyphenols tse ling ka ho theola taolo ea IkappaB kinase ho macrophages.
• cBioPortal bakeng sa Cancer Genomics
• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.