Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Coriander lijong tsa bona?

Lintlha-khōlō Tsa

Coriander e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Coriander bakeng sa bakuli ba mofets'e e ipapisitse le lintlha tse ngata joalo ka sesupo sa mofets'e, chemotherapy, liphekolo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Coriander e ka thusa ba nang le Tumor ea Primary Solitary Fibrous Tumor e tšoaroang ke Avastin, empa e ka 'na ea se ke ea e-ba molemo ho bakuli ba fumanang Gemcitabine bakeng sa Primary Inflammatory Myofibroblastic Tumor. Ho feta moo, le hoja Coriander e ka thusa batho ba nang le "KMT2D" ea kotsi ea lefutso, e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea lefutso "ALK". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Coriander bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tse bohlokoa joalo ka mofuta oa mofetše, mekhoa ea kalafo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Coriander ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholo-holo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o shebane le litlamorao tse akaretsang tsa likarolo tsohle tse sebetsang lijong / litlatsetso tse joalo ka Coriander ho fapana le ho lekola motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka botlalo. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Coriander lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho sebelisa Coriander haeba u na le liphatsa tsa lefutso tse amanang le mofetše oa KMT2D? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la ALK? Na ho molemo ho kenyelletsa Coriander lijong tsa hau haeba u fumanoa u e-na le Primary Inflammatory Myofibroblastic Tumor, kapa haeba tlhahlobo ea hau e le Primary Solitary Fibrous Tumor? Ho feta moo, tšebeliso ea hau ea Coriander e lokela ho fetoloa joang haeba u ntse u le kalafo ea Avastin kapa haeba moralo oa hau oa kalafo o tloha Avastin ho ea Gemcitabine? Ho bohlokoa ho elelloa hore lipolelo tse bonolo joalo ka 'Coriander ke tsa tlhaho, ka hona li molemo ka linako tsohle' kapa 'Coriander e matlafatsa sesole sa' mele ha lia lekana bakeng sa khetho ea lijo/tlatsetso.

Ho phaella moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Coriander lijong tsa hau haeba ho na le liphetoho tsamaisong ea hau ea phekolo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Coriander lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka litlamorao tse akaretsang tsa biochemical tsa metsoako eohle, u nahane ka lintlha tse kang mofuta oa mofets'e, liphekolo tse ikhethileng tseo u li etsang, liphatsa tsa lefutso. , le khetho ea bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, o kang Primary Solitary Fibrous Tumor kapa Primary Inflammatory Myofibroblastic Tumor, mekhoa ea phekolo e lokela ho hlophisoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le bong.

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofetše ha u etsa qeto ea khetho ea lijo, joalo ka Coriander. Na kotsi ea lefutso bakeng sa mofets'e e bakoang ke phetoho e teng ho KMT2D e na le litlamorao tse tšoanang tsa biochemical le phetoho ho ALK? Ho ea ka pono ea phepo e nepahetseng, na kotsi e amanang le Primary Solitary Fibrous Tumor e lekana le Primary Inflammatory Myofibroblastic Tumor? Ho feta moo, na tlhokomelo ea lijo e lula e tšoana le ho ba kenang Gemcitabine le ba amohelang Avastin? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Coriander - Tlatsetso ea Phepo

Tlatsetso ea Coriander e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyelletsa Linolenic Acid, Vithamine K, Vithamine A, Palmitic Acid le Vithamine C, e 'ngoe le e' ngoe e le teng ka mefuta e sa tšoaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo MYC Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling le Oncogenic Histone Methylation, e laolang likarolo tse mahlonoko tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea tlhaho, ho khetha li-supplement tse loketseng joalo ka Coriander, e le 'ngoe kapa ha li kopane, e fetoha qeto ea bohlokoa maemong a phepo e nepahetseng ea mofets'e. Ha u nahana ho sebelisa Coriander bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Coriander ha se qeto e akaretsang e loketseng mafu a mofetše empa e hloka ho etsoa motho ka mong.

Ho khetha lisebelisoa tsa coriander

Ho araba potso e reng 'Ke lokela ho qoba Coriander neng maemong a Kankere' ho thata hobane karabo ke ea motho ka mong - e mpa feela e le 'Ho ipapisitse le!'. Joalo ka ha kalafo efe kapa efe ea mofetše e kanna ea se sebetse ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Coriander e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le lintho tse ling tse amanang le ho kula kaofela li phetha karolo ea ho tseba hore na Coriander e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqeto tse joalo.

1. Na Li-Supplement tsa Coriander li tla thusa bakuli ba mantlha ba ho ruruha ba Myofibroblastic Tumor ba ntseng ba etsoa kalafo ea Gemcitabine?

Primary Inflammatory Myofibroblastic Tumor e khetholloa ke liphetoho tse itseng tsa liphatsa tsa lefutso, e leng ARID2, FLT4 le IGF1R, e lebisang liphetohong tsa litsela tsa biochemical, haholo-holo Chromatin Remodeling, Angiogenesis, Growth Factor Signaling le PI3K-AKT-MTOR Signaling. Katleho ea kalafo ea mofetše, joalo ka Gemcitabine, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Ka mohlala, tlatsetso ea Coriander, e amang PI3K-AKT-MTOR Signaling, e ka 'na ea se ke ea e-ba khetho e nepahetseng tabeng ea Primary Inflammatory Myofibroblastic Tumor ha e ntse e etsoa Gemcitabine. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Li-Supplement tsa Coriander li tla thusa bakuli ba Primary Solitary Fibrous Tumor ba ntseng ba le kalafo ea Avastin?

Sehlahala sa Mantlha sa Bolutu se Ikemetseng se khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang BRD4, FLI1 le KMT2C, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation le Amino Acid Metabolism. Katleho ea kalafo ea mofets'e, joalo ka Avastin, e khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Coriander ke khetho e utloahalang bakeng sa ba nang le Primary Solitary Fibrous Tumor ba nang le Avastin. Lebaka ke hobane Coriander e susumetsa litsela tse kang MYC Signaling, e ka thibelang mabaka a khanna Primary Solitary Fibrous Tumor kapa ea thusa katleho ea Avastin.

3. Na Li-Supplement tsa Coriander li Sireletsehile ho Batho ba Phelang ba nang le ALK Mutation Associated Genetic Kotsi?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ALK o atisa ho kenyelletsoa liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea mofuta oa ALK e ama litsela kapa mekhoa ea lik'hemik'hale, tse kang RAS-RAF Signaling le Growth Factor Signaling, tse amehang ka ho toba kapa ka tsela e sa tobang ho khanna kankere boemong ba limolek'hule. Ha sehlopha sa liphatsa tsa lefutso se khetholla phetoho ho ALK e amanang le kotsi e eketsehileng ea Central Nervous System, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tlatsetso ea Coriander. Lebaka ke hobane tlatsetso ea Coriander e susumetsa litsela tse kang RAS-RAF Signaling, e ka lebisang liphellong tse mpe molemong oa phetoho ea ALK le maemo a amanang le kankere.

4. Na Li-Supplement tsa Coriander li Sireletsehile ho Batho ba Phelang ba nang le KMT2D Mutation Associated Genetic Kotsi?

KMT2D e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofetše. Liphetoho ho KMT2D li ka sitisa litsela tsa bohlokoa tsa biochemical, ho kenyelletsa le Oncogenic Histone Methylation, e susumetsang nts'etsopele ea mofets'e. Haeba phanele ea liphatsa tsa lefutso ea hau e senola liphetoho tsa KMT2D tse amanang le Bladder Urothelial Carcinoma, nahana ka ho kenyelletsa li-supplement tsa Coriander moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa hantle litsela tse kang Oncogenic Histone Methylation, molemo ka ho fana ka ts'ehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa KMT2D le mathata a amanang le bophelo bo botle.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Coriander, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• Vithamine C e bolaea ka boikhethelo lisele tsa mofetše tsa KRAS le BRAF tse feto-fetohang ka ho tobisa GAPDH.
• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.
• cBioPortal bakeng sa Cancer Genomics
• cBioPortal bakeng sa Cancer Genomics
• Alpha-linolenic acid e sireletsa khahlanong le kotsi e mpe ea matšoafo e bakoang ke lipopolysaccharide ka litsela tse khahlanong le ho ruruha le li-anti-oxidative.
• Karolo ea NF-kappaB le Akt / PI3K ho hanyetsa lisele tsa pancreatic carcinoma khahlanong le lefu la lisele tse bakoang ke gemcitabine.
• Alpha linolenic acid le oleic acid e ekelletsang fatše-laola menyetla e kotsi 'me ka mokhoa o nepahetseng e tšela AMPK/S6 axis ho lisele tsa mofetše tsa OE19 le OE33.
• Karolo ea "tumor microenvironment" ho hanyetsa kalafo ea anti-angiogenic.