Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Cassia Fistula lijong tsa bona?

Lintlha-khōlō Tsa

Cassia Fistula e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me hangata e sebelisoa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Cassia Fistula bakeng sa bakuli ba mofets'e e ipapisitse le lintlha tse ngata joalo ka sesupo sa mofetše, chemotherapy, liphekolo tse ling, le lefutso la hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Cassia Fistula e ka thusa ba nang le Primary Sinonasal Adenocarcinoma ba nang le Radiation, empa e ka 'na ea se ke ea e-ba molemo ho bakuli ba fumanang Avastin bakeng sa Tlhahala ea Mantlha ea Masoli a Mantlha. Ho feta moo, le hoja Cassia Fistula e ka thusa batho ba nang le lefutso la kotsi, e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea liphatsa tsa lefutso "ASXL1". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho tšoaneleha ha Cassia Fistula bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa tse kang mofuta oa mofetše, mekhoa ea phekolo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Cassia Fistula ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / li-supplement tse kang Cassia Fistula ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Cassia Fistula lijong tsa hau e le lijo kapa tlatsetso? Na ho bohlokoa ho ja Cassia Fistula haeba u na le liphatsa tsa lefutso tsa mofets'e tse amanang le lefutso? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea liphatsa tsa lefutso e bakoa ke lefutso la ASXL1? Na ho molemo ho kenyelletsa Cassia Fistula lijong tsa hau haeba u fumanoa u e-na le Primary Solitary Fibrous Tumor, kapa haeba tlhahlobo ea hau e le Primary Sinonasal Adenocarcinoma? Ho feta moo, tšebeliso ea hau ea Cassia Fistula e lokela ho fetoloa joang haeba u ntse u le kalafo ea Mahlaseli kapa haeba leano la hau la kalafo le tloha ho Radiation ho ea Avastin? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Cassia Fistula ke tsa tlhaho, kahoo ho molemo ka linako tsohle' kapa 'Cassia Fistula e matlafatsa sesole sa' mele' ha li lekane bakeng sa khetho ea lijo/tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Cassia Fistula lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Cassia Fistula lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka liphello tse akaretsang tsa lik'hemik'hale tsa metsoako eohle, u nahane ka lintlha tse kang mofuta oa kankere, phekolo e khethehileng eo u ntseng u e etsa, liphatsa tsa lefutso. maemo a pele, le khetho ea mokhoa oa bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, o kang Primary Sinonasal Adenocarcinoma kapa Primary Solitary Fibrous Tumor, mekhoa ea phekolo e lokela ho hlophisoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le bong.”

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofets'e ha u etsa qeto ea khetho ea lijo, joalo ka Cassia Fistula. Na kotsi ea lefutso bakeng sa mofetše e bakoang ke phetoho ea lefutso e na le litlamorao tse tšoanang tsa biochemical joalo ka phetoho ho ASXL1? Ho ea ka pono ea phepo e nepahetseng, na kotsi e amanang le Primary Sinonasal Adenocarcinoma e lekana le Primary Solitary Fibrous Tumor? Ho feta moo, na tlhokomeliso ea lijo e lula e tšoana bakeng sa ba nang le Avastin le ba amohelang Radiation? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Cassia Fistula - Tlatsetso ea Phepo

Tlatsetso ea Cassia Fistula e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyeletsoa Sennoside B, e 'ngoe le e' ngoe e teng ka maemo a fapaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo Notch Signaling, MYC Signaling le Hypoxia, e laolang likarolo tsa bohlokoa tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea likokoana-hloko, ho khetha li-supplement tse loketseng tse kang Cassia Fistula, e le 'ngoe kapa e kopane, e fetoha qeto ea bohlokoa tabeng ea phepo e nepahetseng ea kankere. Ha u nahana ka ho sebelisa Cassia Fistula bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena le mekhoa e fapaneng. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Cassia Fistula ha se qeto e akaretsang e loketseng mefuta eohle ea mofets'e empa e hloka hore motho a e etse.

Ho Khetha Lisebelisoa tsa Cassia Fistula

Ho araba potso e reng 'Ke lokela ho qoba Cassia Fistula neng maemong a Kankere' ho thata hobane karabo e itšetlehile haholo ka motho ka mong - e mpa feela e le 'Ho itšetlehile!'. Hoa tšoana le kamoo phekolo leha e le efe ea kankere e ka 'nang ea se ke ea sebetsa ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Cassia Fistula e fapana ho itšetlehile ka maemo a botho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, lisebelisoa tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le ho kula hofe kapa hofe ho phetha karolo ea ho tseba hore na Cassia Fistula e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqetong tse joalo.

1. Na Li-Supplement tsa Cassia Fistula li tla thusa bakuli ba Primary Solitary Fibrous Tumor ba ntseng ba etsoa kalafo ea Avastin?

Primary Solitary Fibrous Tumor e khetholloa ka liphetoho tse itseng tsa liphatsa tsa lefutso, e leng BRD4, FLI1 le KMT2C, tse lebisang liphetohong tsa litsela tsa biochemical, haholo-holo MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation le Amino Acid Metabolism. Katleho ea kalafo ea mofets'e, joalo ka Avastin, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Mohlala, tlatsetso ea Cassia Fistula, e amang Letšoao la MYC, e kanna ea se be khetho e nepahetseng tabeng ea Primary Solitary Fibrous Tumor ha e etsoa Avastin. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Li-Supplement tsa Cassia Fistula li tla thusa bakuli ba Primary Sinonasal Adenocarcinoma ba ntseng ba etsoa ka Kalafo ea Radiation?

Primary Sinonasal Adenocarcinoma e khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang ATRX, NOTCH1 le PTPRD, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo Notch Signaling le RUNX Signaling. Ho sebetsa hantle ha kalafo ea mofets'e, joalo ka Radiation, ho khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Cassia Fistula ke khetho e utloahalang bakeng sa ba nang le Primary Sinonasal Adenocarcinoma ba nang le Radiation. Lebaka ke hore Cassia Fistula e susumetsa litsela tse kang Notch Signaling, e ka thibelang lintlha tse tsamaisang Primary Sinonasal Adenocarcinoma kapa ea thusa katleho ea Radiation.

3. Na Li-Supplement tsa Cassia Fistula li Sireletsehile ho Batho ba Phelang ba nang le ASXL1 Mutation Associated Genetic Risk?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ASXL1 hangata o kenyeletsoa liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ho mofuta oa ASXL1 e ama litsela kapa lits'ebetso tsa biochemical, joalo ka MYC Signaling, Oncogenic Cancer Epigenetics le Suppressive Histone Methylation, tse amehang ka kotloloho kapa ka tsela e sa tobang ho khanna mofetše boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho ASXL1 e amanang le kotsi e eketsehileng ea Chronic Myelomonocytic Leukemia, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tlatsetso ea Cassia Fistula. Sena ke hobane tlatsetso ea Cassia Fistula e susumetsa litsela tse kang MYC Signaling, e ka lebisang litlamorao tse mpe molemong oa phetoho ea ASXL1 le maemo a amanang le mofets'e.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Cassia Fistula, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.
• cBioPortal bakeng sa Cancer Genomics
• Ho lebisa Notch ho hlola khanyetso ea mahlaseli.
• cBioPortal bakeng sa Cancer Genomics
• Karolo ea "tumor microenvironment" ho hanyetsa kalafo ea anti-angiogenic.