Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Ahcc (e sebetsang Hexose Correlated Compound) lijong tsa bona?

Lintlha-khōlō Tsa

Ahcc (e sebetsang Hexose Correlated Compound) e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Ahcc (e sebetsang ea Hexose Correlated Compound) bakeng sa bakuli ba mofets'e e ipapisitse le lintlha tse ngata joalo ka sesupo sa mofetše, chemotherapy, kalafo tse ling le lefutso la hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Ka mohlala, Ahcc (e sebetsang ea Hexose Correlated Compound) e ka ruisa ba nang le Primary Cutaneous Squamous Cell Carcinoma ba nang le Cemiplimab, empa e ka 'na ea se ke ea e-ba molemo ho bakuli ba fumanang Pazopanib bakeng sa Primary Goblet Cell Carcinoid ea Sehlomathiso. Ho feta moo, le hoja Ahcc (e sebetsang ea Hexose Correlated Compound) e ka thusa batho ba nang le kotsi ea lefutso, e ka 'na ea se ke ea buelloa ho ba nang le kotsi e fapaneng ea lefutso "FLT3". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Ahcc (e sebetsang Hexose Correlated Compound) bakeng sa mokuli oa mofets'e ho bohlokoa hore e be motho ka mong. Lintlha tsa bohlokoa tse kang mofuta oa kankere, mekhoa ea phekolo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Ahcc (e sebetsang Hexose Correlated Compound) ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo ke oa bohlokoa, o lebisa tlhokomelo liphellong tse akaretsang tsa likarolo tsohle tse sebetsang lijong / lisebelisoa tse kang Ahcc (e sebetsang Hexose Correlated Compound) ho e-na le ho hlahloba motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka ho feletseng. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Ahcc (e sebetsang Hexose Correlated Compound) lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho sebelisa Ahcc (e sebetsang ea Hexose Correlated Compound) haeba u na le liphatsa tsa lefutso tse amanang le mofetše? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la FLT3? Na ho molemo ho kenyelletsa Ahcc (active Hexose Correlated Compound) lijong tsa hau haeba u fumanoa u e-na le Primary Goblet Cell Carcinoid of the Appendix, kapa haeba tlhahlobo ea hau e le Primary Cutaneous Squamous Cell Carcinoma? Ho feta moo, tšebeliso ea hau ea Ahcc (e sebetsang ea Hexose Correlated Compound) e lokela ho fetoloa joang haeba u ntse u le kalafo ea Cemiplimab kapa haeba moralo oa hau oa kalafo o tloha Cemiplimab ho ea Pazopanib? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Ahcc (Active Hexose Correlated Compound) ke tsa tlhaho, kahoo ho molemo kamehla' kapa 'Ahcc (active Hexose Correlated Compound) e matlafatsa sesole sa 'mele' ha e lekane bakeng sa khetho ea lijo / tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Ahcc (e sebetsang Hexose Correlated Compound) lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Ahcc (e sebetsang Hexose Correlated Compound) lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka liphello tsa lik'hemik'hale tsa metsoako eohle, u nahane ka lintlha tse kang mofuta oa kankere, phekolo e khethehileng eo ue sebelisang. li ntse li tsoela pele, maemo a liphatsa tsa lefutso, le khetho ea mokhoa oa bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa kankere, o kang Primary Cutaneous Squamous Cell Carcinoma kapa Primary Goblet Cell Carcinoid ea Sehlomathiso, mekhoa ea phekolo e lokela ho etsoa ho latela liphatsa tsa lefutso tsa hlahala, sethaleng sa lefu lena, hammoho le lintlha tse kang lilemo. le bong.”

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofets'e ha u etsa qeto ea khetho ea lijo, joalo ka Ahcc (e sebetsang Hexose Correlated Compound). Na ho na le kotsi ea liphatsa tsa lefutso bakeng sa mofetše e bakoang ke phetoho ea mofuta oa FLT3? Ho latela pono ea phepo e nepahetseng, na kotsi e amanang le Primary Cutaneous Squamous Cell Carcinoma e lekana le Primary Goblet Cell Carcinoid ea Sehlomathiso? Ho feta moo, na tlhokomelo ea lijo e lula e tšoana bakeng sa ba ntseng ba feta Pazopanib le ba amohelang Cemiplimab? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Ahcc (e sebetsang Hexose Correlated Compound) - Tlatsetso ea Phepo

Tlatsetso ea Ahcc (e sebetsang ea Hexose Correlated Compound) e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho kenyelletsa Ahcc (Active Hexose Correlated Compound) le Alpha-glucan, e 'ngoe le e 'ngoe e teng ka mefuta e sa tšoaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholoholo Natural Killer Cell Activation le MAPK Signaling, e laolang likarolo tsa bohlokoa tsa mofets'e maemong a lisele, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea likokoana-hloko, ho khetha li-supplement tse loketseng joaloka Ahcc (e sebetsang Hexose Correlated Compound), e le 'ngoe kapa e kopane, e fetoha qeto ea bohlokoa tabeng ea phepo ea mofetše. Ha u nahana ho sebelisa Ahcc (Active Hexose Correlated Compound) bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Ahcc (Access Hexose Correlated Compound) ha se qeto e akaretsang e loketseng mats'oafo ohle empa e hloka ho etsoa motho ka mong.

Ho Khetha Lisebelisoa tsa Ahcc (Hexose Correlated Compound) e sebetsang

Ho araba potso e reng 'Ke lokela ho qoba neng Ahcc (e sebetsang Hexose Correlated Compound) maemong a Kankere' ho thata hobane karabo e itšetlehile haholo ka motho ka mong - e mpa feela e le 'Ho itšetlehile!'. Joalo ka ha kalafo efe kapa efe ea mofetše e kanna ea se sebetse hantle ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Ahcc (e sebetsang ea Hexose Correlated Compound) e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa kankere, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le ho kula hofe kapa hofe ho phetha karolo ea ho tseba hore na Ahcc (Active Hexose Correlated Compound) e loketse kapa e lokela ho qojoa, e hatisa. bohlokoa ba ho nahanela motho ka mong liqetong tse joalo.

1. Na Ahcc (e sebetsang Hexose Correlated Compound) Tlatsetso e tla rua molemo Primary Goblet Cell Carcinoid ea Bakuli ba Sehlomathiso ba etsoang kalafo ea Pazopanib?

Primary Goblet Cell Carcinoid ea Sehlomathiso e khetholloa ka liphetoho tse itseng tsa liphatsa tsa lefutso, e leng ALK, APC le ARID1A, tse lebisang liphetohong litseleng tsa biochemical, haholo-holo MAPK Signaling, Growth Factor Signaling, JAK-STAT Signaling, Angiogenesis, Androgen Signaling le Chromatin Remodeling. Katleho ea kalafo ea mofets'e, joalo ka Pazopanib, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Leano le nepahetseng le kenyelletsa ho hokahanya ts'ebetso ea kalafo le litsela tse tsamaisang mofets'e, ka hona ho netefatsa mokhoa oa motho ka mong le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa lisebelisoa tsa phepo e nepahetseng tse ka hananang le litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Ka mohlala, tlatsetso ea Ahcc (e sebetsang ea Hexose Correlated Compound), e amang MAPK Signaling, e ka 'na ea se ke ea e-ba khetho e nepahetseng tabeng ea Primary Goblet Cell Carcinoid ea Sehlomathiso ha ho etsoa Pazopanib. Lebaka ke hobane e ka 'na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Ahcc (e sebetsang Hexose Correlated Compound) Li-Supplement li tla ruisa bakuli ba Primary Cutaneous Squamous Cell Carcinoma ba ntseng ba etsoa kalafo ea Cemiplimab?

Primary Cutaneous Squamous Cell Carcinoma e khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang TTN, USH2A le CSMD3, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo Natural Killer Cell Activation. Ho sebetsa hantle ha kalafo ea mofets'e, joalo ka Cemiplimab, ho khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Ahcc (e sebetsang ea Hexose Correlated Compound) ke khetho e utloahalang bakeng sa ba nang le Primary Cutaneous Squamous Cell Carcinoma ba fetang Cemiplimab. Sena ke hobane Ahcc (e sebetsang Hexose Correlated Compound) e susumetsa litsela tse kang Natural Killer Cell Activation, e ka thibelang mabaka a khanna Primary Cutaneous Squamous Cell Carcinoma kapa ea rua molemo katlehong ea Cemiplimab.

3. Na Ahcc (e sebetsang Hexose Correlated Compound) e Tlatselletsa e Sireletsehile Bakeng sa Batho ba Phelang ba nang le Kotsi ea Liphatsa tsa lefutso ea FLT3 Mutation?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa FLT3 hangata o kenyelelitsoe liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea mofuta oa FLT3 e ama litsela kapa mekhoa ea lik'hemik'hale, tse kang JAK-STAT Signaling, MAPK Signaling le PI3K-AKT-MTOR Signaling, tse amehang ka ho toba kapa ka tsela e sa tobang ho khanna kankere boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho FLT3 e amanang le kotsi e eketsehileng ea Acute Myeloid Leukemia, mabaka a saense a fana ka maikutlo a ho qoba tšebeliso ea tlatsetso ea Ahcc (e sebetsang ea Hexose Correlated Compound). Lebaka ke hobane tlatsetso ea Ahcc (e sebetsang ea Hexose Correlated Compound) e susumetsa litsela tse kang MAPK Signaling, e ka lebisang liphellong tse mpe ho latela phetoho ea FLT3 le maemo a amanang le mofetše.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo, ho kenyelletsa lijo le li-supplement tse kang Ahcc (e sebetsang Hexose Correlated Compound) bakeng sa melemo ea eona, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le kankere.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• Ho lebisa CD73 ho ntlafatsa ts'ebetso ea antitumor ea anti-PD-1 le anti-CTLA-4 mAbs.
• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.
• cBioPortal bakeng sa Cancer Genomics
• Meeli | Sebopeho sa lik'hemik'hale le ts'ebetso ea 'mele ea ho itšireletsa mafung ea Glucan e tsoang ho Rhizoma Acori Tatarinowii
• Tlhahlobo ea genomic ea metastatic cutaneous squamous cell carcinoma.
• Karolo ea "tumor microenvironment" ho hanyetsa kalafo ea anti-angiogenic.
• Liphello tsa immunomodulatory le anticancer tsa motsoako o sebetsang oa hemicellulose (AHCC)