Ke mofetše ofe o ka ruang molemo ka ho kenyelletsa Apple lijong tsa bona?

Lintlha-khōlō Tsa

Apple e tsebahala haholo ka melemo ea eona ea bophelo bo botle 'me e sebelisoa khafetsa ke bakuli ba mofetše le ba kotsing ea lefutso. Leha ho le joalo, polokeho le katleho ea Apple bakeng sa bakuli ba mofetše li ipapisitse le lintlha tse ngata joalo ka sesupo sa mofets'e, chemotherapy, kalafo tse ling le liphatsa tsa lefutso tsa hlahala. Ho tseba hore lijo tse ling le li-supplement, tse kang grapefruit le spinach, li ka 'na tsa sebelisana hampe le meriana ea mofetše le ho baka maikutlo a mabe ho bohlokoa.

Lijo li bohlokoa bakeng sa kalafo ea mofets'e kaha li ka ama litholoana tsa kalafo. Bakuli ba mofetše ba tlameha ho khetha ka hloko le ho kenyelletsa lijo tse loketseng le li-supplement lijong tsa bona. Mohlala, Apple e ka tsoela ba nang le Tumor ea Primary Solitary Fibrous Tumor e tšoaroang ke Avastin, empa e kanna ea se be molemo ho bakuli ba fumanang Radiation bakeng sa Primary Urethral Squamous Cell Carcinoma. Ho feta moo, leha Apple e ka thusa batho ba nang le "CREBBP" ea lefutso, e kanna ea se khothaletsoe bakeng sa ba nang le kotsi e fapaneng ea lefutso "ALK". Ho iketsetsa merero ea ho ja ho latela bophelo bo botle, kalafo, le liphatsa tsa lefutso ho bohlokoa.

Ho utloisisa hore ho etsa qeto mabapi le ho lekana ha Apple bakeng sa mokuli oa mofets'e ho bohlokoa ho ba motho ka mong. Lintlha tsa bohlokoa tse kang mofuta oa mofetše, mekhoa ea phekolo, liphatsa tsa lefutso, likotsi tsa lefutso, lilemo, boima ba 'mele le mokhoa oa bophelo li bohlokoa ho etsa qeto ea hore na Apple ke khetho e nepahetseng. Liphatsa tsa lefutso le liphatsa tsa lefutso, haholoholo, li nahanoa haholo. Kaha lintlha tsena li ka fetoha, ho bohlokoa ho hlahloba khafetsa le ho fetola khetho ea lijo ho tsamaisana le liphetoho tsa boemo ba bophelo bo botle le kalafo.

Qetellong, mokhoa o akaretsang oa khetho ea lijo o bohlokoa, o shebane le litlamorao tse akaretsang tsa likarolo tsohle tse sebetsang lijong / litlatsetso joalo ka Apple ho fapana le ho lekola motsoako o mong le o mong o sebetsang ka thoko kapa ho o hlokomoloha ka botlalo. Maikutlo ana a pharaletseng a khothalletsa mokhoa o utloahalang le oa saense oa moralo oa lijo bakeng sa mofetše.

Kakaretso e Khutšoanyane

Tšebeliso ea lijo tse thehiloeng limela le li-supplement, tse kang livithamini, litlama, liminerale, li-probiotics, le lisebelisoa tse fapaneng tse khethehileng, li ntse li eketseha har'a bakuli ba mofetše. Li-supplement tsena li etselitsoe ho fana ka metsoako e phahameng ea metsoako e sebetsang, eo bongata ba eona e leng lijong tse fapaneng. Khokahano le mefuta e fapaneng ea metsoako e sebetsang e fapana lipakeng tsa lijo tse felletseng le li-supplement. Lijo hangata li fana ka mefuta e mengata ea metsoako e sebetsang empa maemong a tlase, athe li-supplement li fana ka metsoako e phahameng ea metsoako e itseng.

Ha ho nahanoa ka mesebetsi e fapaneng ea saense le ea tlhaho ea motsoako o mong le o mong o sebetsang boemong ba limolek'hule, ho bohlokoa ho ikarabella bakeng sa litlamorao tse kopaneng tsa likarolo tsena ha u etsa qeto ea lijo le li-supplement tseo u ka li jang kapa che.

Ho hlaha potso ea bohlokoa: Na u lokela ho kenyelletsa Apple lijong tsa hau e le ntho ea lijo kapa tlatsetso? Na ho bohlokoa ho ja Apple haeba u na le liphatsa tsa lefutso tse amanang le mofetše oa CREBBP? Ho thoe'ng haeba ho e-na le hoo kotsi ea hau ea lefutso e bakoa ke lefutso la ALK? Na ho molemo ho kenyelletsa Apple lijong tsa hau haeba u fumanoa u e-na le Primary Urethral Squamous Cell Carcinoma, kapa haeba tlhahlobo ea hau e le Primary Solitary Fibrous Tumor? Ho feta moo, tšebeliso ea hau ea Apple e lokela ho fetoloa joang haeba u ntse u le kalafo ea Avastin kapa haeba moralo oa hau oa kalafo o tloha ho Avastin ho ea ho Radiation? Ho bohlokoa ho hlokomela hore lipolelo tse bonolo tse kang 'Apple ke ea tlhaho, kahoo e lula e le molemo' kapa 'Apple e matlafatsa boits'ireletso ba mmele' ha e lekane bakeng sa khetho ea lijo / tlatsetso.

Ho feta moo, ho bohlokoa ho hlahloba bocha ho nepahala ha ho kenyelletsa Apple lijong tsa hau haeba ho na le liphetoho mokhoeng oa hau oa kalafo. Ka bokhutšoanyane, ha u etsa liqeto mabapi le ho kenyelletsa lijo kapa li-supplement tse kang Apple lijong tsa hau bakeng sa melemo ea eona, u lokela ho nahana ka litlamorao tse akaretsang tsa biochemical ea metsoako eohle, u nahane ka lintlha tse kang mofuta oa mofets'e, kalafo e ikhethileng eo u e fuoang, liphatsa tsa lefutso. , le khetho ea bophelo.

Cancer

Kankere e ntse e le phephetso e khōlō lefapheng la bongaka, hangata e bakang matšoenyeho a atileng. Leha ho le joalo, tsoelo-pele ea morao-rao e ntlafalitse liphello tsa phekolo, haholo-holo ka mekhoa ea phekolo ea motho ka mong, mekhoa ea ho hlahloba e sa hlaseleng ka ho sebelisa lisampole tsa mali le mathe, le nts'etsopele ea immunotherapy. Ho lemoha kapele le ho kenella ka nako ho bile bohlokoa ho ba le tšusumetso e ntle liphellong tsohle tsa phekolo.

Teko ea liphatsa tsa lefutso e fana ka ts'episo e kholo ea ho lekola kotsi ea mofetše le ho ba kotsing kapele. Leha ho le joalo, ho batho ba bangata ba nang le mekhoa ea malapa le ea liphatsa tsa lefutso ho kankere, mekhoa ea phekolo ea phekolo, esita le ka ho hlahloba kamehla, hangata e lekanyelitsoe kapa ha e eo. Hang ha ho fumanoa hore o na le mofuta o itseng oa mofetše, o kang Primary Solitary Fibrous Tumor kapa Primary Urethral Squamous Cell Carcinoma, mekhoa ea phekolo e lokela ho etsoa ho latela liphatsa tsa lefutso tsa hlahala, boemo ba lefu lena, hammoho le lintlha tse kang lilemo le bong. ”

Ka mor'a kalafo, tlhahlobo e tsoelang pele e bohlokoa ho bona matšoao leha e le afe a ho khutlela mokhoeng oa mofets'e le ho tsebisa liqeto tse latelang. Bakuli ba bangata ba mofetše le ba kotsing hangata ba batla likeletso mabapi le ho kenyelletsa lijo tse itseng le li-supplement lijong tsa bona, e leng se phethang karolo ea bohlokoa ts'ebetsong ea bona ea ho etsa liqeto ka kakaretso mabapi le tsamaiso ea bophelo bo botle.

Potso ea bohlokoa ke hore na ho ameha likotsing tsa lefutso le tlhahlobo e khethehileng ea mofetše ha u etsa qeto mabapi le khetho ea lijo, joalo ka Apple. Na kotsi ea lefutso bakeng sa mofets'e e bakoang ke phetoho e teng ho CREBBP e na le litlamorao tse ts'oanang tsa biochemical joalo ka phetoho ho ALK? Ho ea ka pono ea phepo e nepahetseng, na kotsi e amanang le Primary Solitary Fibrous Tumor e lekana le Primary Urethral Squamous Cell Carcinoma? Ho feta moo, na tlhokomelo ea lijo e lula e tšoana bakeng sa ba nang le Radiation le ba amohelang Avastin? Lintlha tsena li bohlokoa ho etsa khetho e nepahetseng ea lijo bakeng sa batho ba nang le likotsi tse fapaneng tsa lefutso le kalafo ea mofets'e.

Apple - Tlatsetso ea Phepo

Tlatsetso ea Apple e kenyelletsa mefuta e mengata ea metsoako e sebetsang, ho akarelletsa le Glucaric Acid, Catechin, Procyanidin C1, Glycine le Quercetin 3-rutinoside, e 'ngoe le e' ngoe e teng ka mefuta e sa tšoaneng. Lithako tsena li susumetsa litsela tsa limolek'hule, haholo-holo MYC Signaling, RAS-RAF Signaling, JAK-STAT Signaling le Histone/Protein Acetylation, e laolang likarolo tse mahlonoko tsa mofets'e maemong a cellular, joalo ka kholo ea tumor, ho ata le lefu la lisele. Ka lebaka la tšusumetso ena ea tlhaho, ho khetha li-supplement tse loketseng joalo ka Apple, e le 'ngoe kapa e kopane, e fetoha qeto ea bohlokoa maemong a phepo e nepahetseng ea mofets'e. Ha u nahana ho sebelisa Apple bakeng sa mofetše, ho bohlokoa ho nahana ka lintlha tsena tse fapaneng le mekhoa. Lebaka ke hobane, joalo ka kalafo ea mofets'e, ts'ebeliso ea Apple ha se qeto e akaretsang e loketseng batho bohle ba mofets'e empa e hloka ho etsoa motho ka mong.

Ho Khetha Lisebelisoa tsa Apple

Ho araba potso e reng 'Ke lokela ho qoba Apple neng maemong a Kankere' ho thata hobane karabo ke ea motho ka mong - e mpa feela e le 'Ho ipapisitse le!'. Joalo ka ha kalafo efe kapa efe ea mofetše e kanna ea se sebetse ho mokuli e mong le e mong, bohlokoa le polokeho kapa melemo ea Apple e fapana ho latela maemo a motho. Lintlha tse kang mofuta o itseng oa mofetše, liphatsa tsa lefutso, phekolo ea morao-rao, li-supplement tse ling tse nkiloeng, mekhoa ea bophelo, BMI, le ntho leha e le efe ea ho kula kaofela li phetha karolo ea ho tseba hore na Apple e nepahetse kapa e lokela ho qojoa, e totobatsa bohlokoa ba ho nahanela motho ka mong. liqeto tse joalo.

1. Na Apple Supplements e tla thusa bakuli ba Primary Urethral Squamous Cell Carcinoma ba ntseng ba etsoa kalafo ea Radiation?

Primary Urethral Squamous Cell Carcinoma e tšoauoa ka liphetoho tse itseng tsa liphatsa tsa lefutso, e leng BLM, BRCA1 le CTCF, tse lebisang ho liphetoho litseleng tsa biochemical, haholo-holo RAS-RAF Signaling, Androgen Signaling le DNA Repair. Katleho ea kalafo ea mofetše, joalo ka Radiation, e ipapisitse le mokhoa oa eona oa ts'ebetso litseleng tsena tse ikhethileng. Mokhoa o nepahetseng o kenyelletsa ho hokahanya ketso ea kalafo le litsela tse tsamaisang mofetše, ka hona ho netefatsa mokhoa o ikhethileng le o sebetsang. Maemong a joalo, ho bohlokoa ho qoba lijo kapa litlatsetso tsa phepo e nepahetseng tse ka thibelang litlamorao tsa kalafo kapa tsa fokotsa tumellano ena. Mohlala, tlatsetso ea Apple, e amang Letšoao la RAS-RAF, e kanna ea se be khetho e nepahetseng tabeng ea Primary Urethral Squamous Cell Carcinoma ha o ntse o le Radiation. Lebaka ke hobane e ka ’na ea mpefatsa tsoelo-pele ea lefu lena kapa ea kena-kenana le katleho ea phekolo. Ha u khetha moralo oa phepo e nepahetseng, ho bohlokoa ho nahana ka lintlha tse kang mofuta oa mofets'e, kalafo e tsoelang pele, lilemo, bong, BMI, mokhoa oa bophelo, le liphetoho life kapa life tse tsebahalang tsa lefutso.

2. Na Apple Supplements e tla thusa bakuli ba Primary Solitary Fibrous Tumor ba ntseng ba le kalafo ea Avastin?

Sehlahala sa Mantlha sa Bolutu se Ikemetseng se khetholloa ka liphetoho tse khethehileng tsa liphatsa tsa lefutso, tse kang BRD4, FLI1 le KMT2C, tse hlahisang liphetoho litseleng tsa lik'hemik'hale, haholo-holo MYC Signaling, Chromatin Remodeling, DNA Repair, Oncogenic Histone Methylation le Amino Acid Metabolism. Katleho ea kalafo ea mofets'e, joalo ka Avastin, e khethoa ke tšebelisano ea eona le litsela tsena. Sepheo ke ho netefatsa hore phekolo e lumellana hantle le litsela tse tsamaisang mofetše, e leng ho nolofalletsang mokhoa oa phekolo ea motho ka mong. Tabeng ena, ho lokela ho nahanoa ka lijo kapa li-supplement tse tsamaellanang le kalafo kapa tse matlafatsang tekano ena. Ka mohlala, tlatsetso ea Apple ke khetho e utloahalang bakeng sa ba nang le Primary Solitary Fibrous Tumor ba nang le Avastin. Sena ke hobane Apple e susumetsa litsela tse kang MYC Signaling, e ka thibelang lintlha tse khannang Primary Solitary Fibrous Tumor kapa ea thusa katleho ea Avastin.

3. Na Apple Supplements e Sireletsehile ho Batho ba Phelang ba nang le ALK Mutation Associated Genetic Risk?

Likhamphani tse fapaneng li fana ka liphanele tsa lefutso bakeng sa ho lekola kotsi ea lefutso ea mefuta e fapaneng ea mofets'e. Liphanele tsena li kenyelletsa liphatsa tsa lefutso tse amanang le kankere ea matsoele, ea mahe a bomme, ea popelo, ea senya le ea mala. Ho lekola liphatsa tsa lefutso tsena ho ka netefatsa tlhahlobo le ho tsebisa mekhoa ea kalafo le taolo. Ho tseba phapang e bakang mafu ho ka thusa ho ea pele tlhahlobong le tlhahlobong ea beng ka bona ba ka bang kotsing. Mofuta oa ALK o atisa ho kenyelletsoa liphanele tsena bakeng sa tlhahlobo ea kotsi ea mofetše.

Phetoho ea mofuta oa ALK e ama litsela kapa lits'ebetso tsa biochemical, joalo ka JAK-STAT Signaling le Growth Factor Signaling, tse amehang ka kotloloho kapa ka tsela e sa tobang ho khanna mofetše boemong ba limolek'hule. Ha phanele ea liphatsa tsa lefutso e supa phetoho ho ALK e amanang le kotsi e ntseng e eketseha ea Sisteme e Bohareng ea Nervous, mabaka a mahlale a fana ka maikutlo a ho qoba tšebeliso ea Apple ea tlatsetso. Sena ke hobane tlatsetso ea Apple e susumetsa litsela tse kang JAK-STAT Signaling, e ka lebisang litlamorao tse mpe molemong oa phetoho ea ALK le maemo a amanang le mofets'e.

4. Na Apple Supplements e Sireletsehile ho Batho ba Phelang ba nang le CREBBP Mutation Associated Genetic Risk?

CREBBP e bapala karolo ea bohlokoa tlhahlobong ea kotsi ea mofetše. Liphetoho ho CREBBP li ka sitisa litsela tsa bohlokoa tsa biochemical, ho kenyelletsa le Histone/Protein Acetylation, e susumetsang nts'etsopele ea mofets'e. Haeba phanele ea hau ea liphatsa tsa lefutso e senola liphetoho tsa CREBBP tse amanang le Follicular Lymphoma, nahana ka ho kenyelletsa li-supplement tsa Apple moralong oa hau oa phepo. Li-supplement tsena li ka susumetsa hantle litsela tse kang Histone/Protein Acetylation, ho rua molemo ka ho fana ka tšehetso e nepahetseng bakeng sa batho ba nang le liphetoho tsa CREBBP le mathata a amanang le bophelo bo botle.

Ha re phethela

Lintho tse peli tsa bohlokoa ka ho fetisisa tseo u lokelang ho li hopola ke hore phekolo ea kankere le phepo e nepahetseng ha ho mohla li tšoanang ho bohle. Phepo e nepahetseng, ho kenyelletsa lijo le li-supplement joalo ka Apple, ke sesebelisoa se sebetsang se ka laoloang ke uena ha u ntse u tobane le mofetše.

“Ke lokela ho ja eng?” ke potso e atisang ho botsoa ke bakuli ba mofetše le ba kotsing ea ho tšoaroa ke mofetše. Karabo e nepahetseng ke hore e ipapisitse le lintlha tse kang mofuta oa mofets'e, liphatsa tsa lefutso tsa hlahala, kalafo ea hajoale, ho kula, mokhoa oa bophelo le BMI.

Fumana phepo ea hau ea phepo e nepahetseng bakeng sa mofets'e ho tsoa ho addon ka ho tobetsa sehokelo se ka tlase le ho araba lipotso mabapi le mofuta oa mofets'e oa hau, kalafo, mokhoa oa bophelo, ho kula, lilemo le bong.

References

• Ho fumana kokoana-hloko ea maselese haemagglutinin ho tsoa ho mofuta oa L-16 o lengoang litsong tsa lisele tsa mantlha.
• Chromatography ea mokelikeli e sebetsang hantle e nang le tlhahlobo ea diode-array bakeng sa ho tseba metsoako ea phenolic lekhapetleng le makhasi a mefuta e fapaneng ea liapole.
• Free-radical-scaveging and antioxidant activities of secondary metabolites from reded cv. Litholoana tsa apole tsa Annurca.
• cBioPortal bakeng sa Cancer Genomics
• cBioPortal bakeng sa Cancer Genomics
• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.