Lijo bakeng sa Kankere ea tšoelesa ea tšoelesa ea tšoelesa ea senya e Hanang ho Lahleloa!

Selelekela

Lijo bakeng sa Kankere ea Prostate e Hanelang ho Lahloa li lokela ho etsoa bakeng sa motho ka mong hape li tlameha ho ikamahanya le maemo ha kalafo ea mofetše kapa liphatsa tsa lefutso tsa hlahala li fetoha. Ho iketsetsa motho le ho ikamahanya le maemo ho tlameha ho nahanela metsoako eohle e sebetsang kapa li-bioactive tse fumanehang lijong tse fapaneng mabapi le baeloji ea mofetše, liphatsa tsa lefutso, kalafo, maemo a bophelo le likhetho tsa lijo. Kahoo le hoja phepo e nepahetseng e le e 'ngoe ea liqeto tsa bohlokoa haholo tseo mokuli oa mofetše le motho ea kotsing ea mofetše a lokelang ho li etsa - mokhoa oa ho khetha lijo tseo u ka li jang ha se mosebetsi o bonolo.

Bakeng sa Kankere ea Prostate e Hanang ho Lahlela, na ho na le taba hore na motho o ja meroho, litholoana, linate, lipeo life?

Potso e atileng haholo ea phepo e botsoang ke bakuli ba mofets'e le batho ka bomong ba kotsing ea mofets'e ke - bakeng sa mofets'e o kang Castration-resistant Prostate Cancer na ho na le taba hore na ke ja lijo life le tseo ke sa li jeng? Kapa haeba ke latela lijo tse thehiloeng limela na hoo ho lekane bakeng sa mofetše o kang Castration-resistant Prostate Cancer?

Mohlala, na ho na le taba hore moroho oa Wild Carrot o jeoa haholo ha o bapisoa le Ostrich Fern? Na ho etsa phapang haeba litholoana tse tloaelehileng tsa Chokecherry li khethoa ho feta Java Plum? Hape haeba ho etsoa khetho e tšoanang bakeng sa linate/lipeo tse kang Common Hazelnut holim'a Brazil Nut le bakeng sa limela tse kang Adzuki Bean holim'a Cowpea. 'Me haeba seo ke se jang se le bohlokoa - joale motho o tseba joang lijo tse buelloang bakeng sa Kankere ea Prostate e hanyetsanang le Castration 'me na ke karabo e tšoanang ho bohle ba nang le tšoaetso e tšoanang kapa kotsi ea lefutso?

Ee! Lijo tseo u li jang ke tsa bohlokoa bakeng sa Kankere ea Prostate e hananang le Castration!

Litlhahiso tsa lijo li ka 'na tsa se ke tsa tšoana ho bohle' me li ka fapana esita le bakeng sa tlhahlobo e tšoanang le kotsi ea lefutso.

Lijo tsohle (meroho, litholoana, linate, lipeo, li-pulses, oli joalo-joalo) le litlatsetso tsa phepo li entsoe ka metsoako e fetang e le 'ngoe e sebetsang ea molek'hule kapa bio-active ka tekanyo le bongata bo fapaneng. Sejo se seng le se seng se sebetsang se na le mokhoa o ikhethileng oa ts'ebetso - e ka bang ts'ebetso kapa ho thibela litsela tse fapaneng tsa biochemical. Lijo le li-supplement tse khothalletsoang habonolo ke tse sa bakeng keketseho ea limolek'hule tsa mofetše empa li li fokotsa. Ho seng joalo, lijo tseo ha lia lokela ho khothaletsoa. Lijo li na le metsoako e mengata e sebetsang - ka hona, ha u hlahloba lijo le li-supplement, u lokela ho nahana ka phello ea metsoako eohle e sebetsang ka bonngoe ho e-na le hore u nahane ka bonngoe.

Mohlala Tloaelehileng Chokecherry e na le metsoako e sebetsang Apigenin, Curcumin, Beta-sitosterol, Lupeol, Myricetin. 'Me Java Plum e na le metsoako e sebetsang ea Apigenin, Ellagic Acid, Curcumin, Beta-sitosterol, Lycopene le mohlomong tse ling.

Phoso e tloaelehileng e entsoeng ha ho etsoa qeto le ho khetha lijo tseo u ka li jang bakeng sa Kankere ea Prostate e hanyetsanang le Castration - ke ho hlahloba feela metsoako e sebetsang e khethiloeng e fumanehang lijong ebe o hlokomoloha tse ling kaofela. Hobane metsoako e fapaneng e sebetsang e fumanehang lijong e kanna ea ba le litlamorao tse fapaneng ho bakhanni ba mofets'e - u ke ke ua khetha metsoako e sebetsang lijong le li-supplement bakeng sa ho etsa qeto ea phepo e nepahetseng bakeng sa Kankere ea Prostate e hananang le Castration.

EE – LIKHETHO TSA LIJO LI BOHLOKOA BAKENG SA KANKERE. LIQETO TSA PHEPO LI TLAMEHA HO NAHANA KA LITABA TSOHLE TSA LIJO.

Tsebo e Hlokahalang Bakeng sa ho Itloaetsa Phepo e Ntle Bakeng sa Kankere ea Prostate e Hanang?

Phepo ea motho ka mong bakeng sa mofetše joalo ka Kankere ea Prostate e hananang le Castration e na le lijo tse khothaletsoang; lijo tse sa khothaletsoang tse nang le mohlala oa diresepe tse etelletsang pele tšebeliso ea lijo tse khothaletsoang. Mohlala oa phepo e nepahetseng o ka bonoa ho sena link tsa.

Ho etsa qeto ea hore na ke lijo life tse khothalelitsoeng kapa che ho rarahane haholo, ho hloka boitsebi ba baeloji ea Kankere ea Prostate e hananang le Castration, mahlale a lijo, liphatsa tsa lefutso, biochemistry hammoho le kutloisiso e ntle ea hore na kalafo ea mofetše e sebetsa joang le bofokoli bo amanang le bona boo kalafo e ka emisang ho sebetsa.

BONYENYANE BO TSEBO BOHLOKOA BAKENG SA PHEPO MOTHO BATHO BA KANKERE KE: BOLOJI YA KANKERE, SAENSE YA DIJO, DIPHEKO LA MOFEPO LE LIFUTSO.

Litšobotsi tsa mofets'e joalo ka Kankere ea Prostate e hanyetsanang le Castration

Lik'hemik'hale tsohle tse kang Kankere ea Prostate e hanyetsanang le Castration e ka khetholloa ka mekhoa e ikhethang ea lik'hemik'hale - mekhoa ea ho saena ea Kankere ea Prostate e hanyetsanang le Castration. Litsela tsa lik'hemik'hale tse kang Cell Cycle, Oncogenic Histone Methylation, Small Molecule Transport, Extracellular Matrix Remodeling ke karolo ea tlhaloso ea signature ea Castration-resistant Prostate Cancer. Liphatsa tsa lefutso tsa mofetše oa motho ka mong li ka fapana, ka hona, tekeno ea bona ea mofetše e ka ikhetha.

Liphekolo tse sebetsang hantle bakeng sa Mofets'e oa Prostate o hananang le Castration li hloka ho ela hloko mekhoa ea lik'hemik'hale e amanang le eona bakeng sa mokuli e mong le e mong oa mofetše le motho ea kotsing ea lefutso. Ka hona liphekolo tse fapaneng tse nang le mekhoa e fapaneng ea liketso li sebetsa hantle ho bakuli ba fapaneng. Ka mokhoa o ts'oanang le ka mabaka a ts'oanang lijo le li-supplement li hloka ho etsoa ka bomong bakeng sa motho ka mong. Kahoo lijo tse ling le li-supplement li khothaletsoa bakeng sa Kankere ea Prostate e hananang le Castration ha u nka kalafo ea mofetše Abiraterone Acetate, 'me lijo tse ling le li-supplement ha li khothalletsoe.

Mehloli e kang cBioPortal 'me ba bang ba bangata ba fana ka lintlha tse sa tsejoeng tse tsoang litekong tsa bongaka bakeng sa matšoao ohle a mofetše. Lintlha tsena li na le lintlha tsa boithuto ba tleliniki joalo ka boholo ba sampole / palo ea bakuli, lihlopha tsa lilemo, bong, morabe, kalafo, sebaka sa tumor le liphetoho life kapa life tsa lefutso.

TP53, SPOP, DYNC1H1, AR le CDK12 ke liphatsa tsa lefutso tse maemong a holimo tse tlalehiloeng bakeng sa Kankere ea Prostate e hanyetsanang le Castration. TP53 e tlalehiloe ho 17.3% ea bakuli ba baemeli ho pholletsa le liteko tsohle tsa bongaka. 'Me SPOP e tlalehiloe ka 11.5%. Lintlha tse kopaneng tsa bakuli li akaretsa lilemo ho tloha ho. 100.0% ea data ea bakuli e tsejoa e le banna. Baeloji ea Kankere ea Prostate e hanyetsanang le Castration hammoho le liphatsa tsa lefutso tse tlalehiloeng hammoho li hlalosa palo ea batho ba emelang litsela tsa lik'hemik'hale tsa kankere ena. Haeba liphatsa tsa lefutso tsa kankere ea motho ka mong kapa liphatsa tsa lefutso tse kenyang kotsi le tsona li tsejoa, seo se lokela ho sebelisoa hape bakeng sa ho iketsetsa lijo.

LIKHETHO TSA PHEPO LI LOKELA HO TŠOANA LE MOTHO E MONG LE E MONG LE SAENYO EA MOTHO EA KANKERE.

Lijo le Tlatsetso bakeng sa Kankere ea Prostate e Hanang

Bakeng sa Bakuli ba Kankere

Bakuli ba mofetše ba nakong ea kalafo kapa ba tlhokomelong ea pholiso ba lokela ho etsa liqeto mabapi le lijo le li-supplement - bakeng sa lik'hilojule tse hlokahalang tsa lijo, ho laola litla-morao life kapa life tsa kalafo le bakeng sa taolo e ntlafetseng ea mofetše. Lijo tsohle tse thehiloeng ho limela ha li lekane, 'me ho khetha le ho etelletsa pele lijo tse ikhethileng le tse etselitsoeng kalafo e tsoelang pele ea mofets'e ho bohlokoa ebile ho rarahane. Mehlala ke ena e fanang ka litataiso bakeng sa ho etsa liqeto tsa phepo e nepahetseng.

Khetha Vegetable WILD Carrot kapa OSTRICH FERN?

Vegetable Wild Carrot e na le metsoako e mengata e sebetsang kapa bioactives tse kang Quercetin, Apigenin, Curcumin, Beta-sitosterol, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang NFKB Signaling, Cell Cycle, PI3K-AKT-MTOR Signaling le Cytokine Signaling le tse ling. Wild Carrot e khothaletsoa bakeng sa Kankere ea Prostate e hananang le Castration ha kalafo ea mofetše e tsoelang pele e le Abiraterone Acetate. Lebaka ke hobane Wild Carrot e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Abiraterone Acetate.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho ea Ostrich Fern ke Apigenin, Curcumin, Beta-sitosterol, Lycopene, Lupeol. Lisebelisoa tsena tse sebetsang li laola mekhoa e fapaneng ea lik'hemik'hale tse kang Oncogenic Cancer Epigenetics le Heat Stress Response le tse ling. Ostrich Fern ha e khothalletsoe bakeng sa Kankere ea Prostate e hanyetsanang le Castration ha phekolo ea mofetše e tsoelang pele e le Abiraterone Acetate hobane e fetola litsela tseo tsa lik'hemik'hale tse etsang hore phekolo ea kankere e se ke ea sebetsa kapa e se ke ea arabela.

KARETE E E HLAHANG EA MERO E E KHOTHATSOENG HO FETA FERN EA NTŠE BAKENG SA Kankere ea tšoelesa ea senya e hananang le Castration LE PHEKO Abiraterone Acetate.

Khetha Litholoana JAVA PLUM kapa COMMON CHOKECHERRY?

Fruit Java Plum e na le metsoako e mengata e sebetsang kapa bioactives tse kang Apigenin, Ellagic Acid, Curcumin, Beta-sitosterol, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang NFKB Signaling, Cell Cycle, PI3K-AKT-MTOR Signaling le Sirtuin Signaling le tse ling. Java Plum e khothaletsoa bakeng sa Kankere ea Prostate e hananang le Castration ha kalafo ea mofetše e tsoelang pele e le Abiraterone Acetate. Lebaka ke hore Java Plum e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Abiraterone Acetate.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tse litholoana tse Tloaelehileng Chokecherry ke Apigenin, Curcumin, Beta-sitosterol, Lupeol, Myricetin. Lisebelisoa tsena tse sebetsang li laola mekhoa e fapaneng ea lik'hemik'hale tse kang Oncogenic Cancer Epigenetics le Heat Stress Response le tse ling. Tloaelo ea Chokecherry ha e khothalletsoe bakeng sa Kankere ea Prostate e hananang le Castration ha kalafo ea mofets'e e tsoelang pele e le Abiraterone Acetate hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofets'e e se ke ea sebetsa kapa e se ke ea arabela.

FRUIT JAVA PLUM E KHOTHATSOA HO FETISISA CHOKECHERRY E TLOAELEHANG BAKENG SA Kankere ea Prostate e hananang le Castration LE PHEKO Abiraterone Acetate.

Khetha Nut COMMON HAZELNUT kapa BRAZIL NUT?

Hazelnut e tloaelehileng e na le metsoako e mengata e sebetsang kapa bioactives tse kang Quercetin, Curcumin, Beta-sitosterol, Lycopene, Lupeol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang NFKB Signaling, Glucocorticoid Signaling, JAK-STAT Signaling le Cell Cycle le tse ling. Hazelnut e tloaelehileng e khothaletsoa bakeng sa Kankere ea Prostate e hananang le Castration ha kalafo ea mofetše e tsoelang pele e le Abiraterone Acetate. Lebaka ke hobane Hazelnut e Tloaelehileng e fetola litsela tseo tsa lik'hemik'hale tse 'nileng tsa tlalehoa ka saense ho hlokomelisa phello ea Abiraterone Acetate.

Tse ling tsa metsoako e sebetsang kapa bioactives Brazil Nut ke Ellagic Acid, Curcumin, Beta-sitosterol, Lupeol, Phloretin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang NFKB Signaling, JAK-STAT Signaling, Epithelial to Mesenchymal Transition le Heat Stress Response le tse ling. Brazil Nut ha e khothalletsoe bakeng sa Kankere ea tšoelesa ea Prostate e hananang le Castration ha kalafo e tsoelang pele ea mofets'e e le Abiraterone Acetate hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

HAZELNUT E TLOAELEHANG E KHOTHATSOE HO PHETHA BRAZIL NUT BAKENG SA Kankere ea Prostate e hananang le Castration LE PHEKO Abiraterone Acetate.

Bakeng sa Batho ba nang le Kotsi ea Liphatsa tsa Kankere

Potso e botsoang ke batho ba nang le kotsi ea lefutso ea Kankere ea Prostate e sa Lapeng kapa histori ea lelapa ke "Ke Lokela ho Ja Eng e Fapaneng le Pele?" le kamoo ba lokelang ho khetha lijo le li-supplement bakeng sa ho laola likotsi tsa lefu lena. Kaha bakeng sa kotsi ea mofets'e ha ho letho le ka etsoang mabapi le kalafo - liqeto tsa lijo le li-supplement li fetoha tsa bohlokoa 'me e le e' ngoe ea lintho tse fokolang haholo tse ka etsoang. Lijo tsohle tse thehiloeng ho limela ha li lekane 'me li ipapisitse le liphatsa tsa lefutso le mokhoa oa ho saena - khetho ea lijo le li-supplement li lokela ho etsoa ke motho ka mong.

Khetha Vegetable GIANT BUTTERBUR kapa BROCCOLI?

Vegetable Giant Butterbur e na le metsoako e mengata e sebetsang kapa bioactives tse kang Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang JAK-STAT Signaling, Cell Cycle, PI3K-AKT-MTOR Signaling le DNA Repair le tse ling. Giant Butterbur e khothaletsoa kotsing ea Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amanang le AR. Sena ke hobane Giant Butterbur e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho Broccoli ke Curcumin, Indole-3-carbinol, Formononetin, Lupeol, Resveratrol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Oxidative Stress le P53 Signaling le tse ling. Broccoli ha e khothalletsoe ha kotsi ea ho ba le Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amahanngoa le AR hobane e eketsa litsela tsa eona.

BUTTERBUR E KHOLO EA MOROO E KHOTHATSOE HO FETA BROCCOLI BAKENG SA AR genetic RISK EA KANKERE.

Khetha Tholoana NANCE kapa GRAPEFRUIT?

Litholoana tsa Nance li na le lisebelisoa tse ngata tse sebetsang kapa li-bioactive tse kang Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang JAK-STAT Signaling, Cell Cycle, PI3K-AKT-MTOR Signaling le DNA Repair le tse ling. Nance e khothaletsoa bakeng sa kotsi ea Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amanang le AR. Lebaka ke hore Nance e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana tsa Grapefruit ke Curcumin, Formononetin, Lupeol, Daidzein, Phloretin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Oxidative Stress le tse ling. Grapefruit ha e khothalletsoe ha kotsi ea Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amahanngoa le AR hobane e eketsa litsela tsa eona.

THOLOANA NANCE E KHOTHATSOA HO FETISISA GRAPEFRUIT BAKENG SA AR genetic RISK YA KANKERE.

Khetha Nut BUTTERNUT kapa BEECH NUT?

Butternut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Cell Cycle, JAK-STAT Signaling le Insulin Signaling le tse ling. Butternut e khothaletsoa kotsing ea Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amanang le AR. Lebaka ke hobane Butternut e eketsa litsela tsa biochemical tse khahlano le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives ho Beech Nut ke Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Oxidative Stress le DNA Repair le tse ling. Beech Nut ha e khothalletsoe ha kotsi ea Kankere ea Prostate e hananang le Castration ha kotsi ea lefutso e amahanngoa le AR hobane e eketsa litsela tsa eona.

BUTTERNUT E KHOTHATSOA HO FETISISA BEECH NUT BAKENG SA AR genetic RISK OF KANKERE.

Ha re phethela

Lijo le li-Supplement tse khethiloeng ke liqeto tsa bohlokoa bakeng sa mofets'e joalo ka Kankere ea Prostate e hananang le Castration. Bakuli ba Kankere ea tšoelesa ea senya e hanyetsanang le ho lahleha le batho ba kotsing ea lefutso ba lula ba e-na le potso ena: "Ke lijo life le li-supplement tsa phepo tse khothalletsoang ho 'na le tse sa buelloang?" Ho na le tumelo e tloaelehileng eo e leng maikutlo a fosahetseng a hore lijo tsohle tse thehiloeng limela li ka ba molemo kapa che empa li ke ke tsa e-ba kotsi. Lijo tse ling le li-supplement li ka kena-kenana le phekolo ea mofetše kapa tsa khothalletsa bakhanni ba limolek'hule tsa mofetše.

Ho na le mefuta e fapaneng ea matšoao a mofets'e joalo ka Kankere ea Prostate e hananang le Castration, e 'ngoe le e' ngoe e na le liphatsa tsa lefutso tse fapaneng tsa tumor tse nang le mefuta e meng ea genomic ho motho ka mong. Ho feta moo kalafo e 'ngoe le e' ngoe ea mofetše le chemotherapy e na le mokhoa o ikhethileng oa ts'ebetso. Sejo se seng le se seng joalo ka Wild Carrot se na le li-bioactive tse fapaneng ka bongata bo fapaneng, tse nang le tšusumetso mekhoeng e fapaneng le e ikhethileng ea litsela tsa biochemical. Tlhaloso ea phepo e nepahetseng ke likhothaletso tsa motho ka mong bakeng sa sesupo sa mofetše, kalafo, liphatsa tsa lefutso, mokhoa oa bophelo le lintlha tse ling. Liqeto tsa phepo e nepahetseng bakeng sa mofetše li hloka tsebo ea biology ea mofets'e, mahlale a lijo le kutloisiso ea liphekolo tse fapaneng tsa chemotherapy. Qetellong ha ho e-na le liphetoho tsa phekolo kapa li-genomics tse ncha li khetholloa - phepo e nepahetseng e hloka ho hlahlojoa bocha.

Tharollo ea motho ka mong ea phepo e nepahetseng ea addon e etsa hore ho be bonolo ho etsa liqeto 'me e tlose menahano eohle ea ho araba potso e reng, "Ke lijo life tseo ke lokelang ho li khetha kapa ho se khethe bakeng sa Kankere ea Prostate e Hanang?". Sehlopha sa li-addon tse nang le taeo e mengata se kenyelletsa lingaka tsa mofetše, bo-ramahlale ba bongaka, baenjiniere ba mananeo le bo-ramahlale ba data.

References

• Nepc Wcm 2016
• Phetoho e fapaneng ea clonal ea kankere ea prostate e hananang le castration.
• Liphello tse thibelang tsa butyric acid, nicotinamide, calcium glucarate li le mong kapa li kopane nakong ea 7, 12-dimethylbenz (a) anthracene e kentse mouse ea letlalo tumorigenesis ka modulation ea K-Ras-PI3K-AKTpathway le li-RNA tse nyenyane tse amanang le tsona.
• Delphinidin e etsa hore ho be le apoptosis ka HDAC3-mediated p53 acetylation le oligomerization liseleng tsa mofetše oa senya.
• Paederia foetida e susumetsa ts'ebetso ea anticancer ka ho fetola li-enzyme tsa phetoho ea chromatin le ho fetola liphatsa tsa lefutso tsa pro-inflammatory cytokine liseleng tsa mofetše oa tšoelesa ea senya.
• Eugenol e matlafatsa ts'ebetso ea cisplatin e khahlanong le mofets'e ka ho thibela lisele tsa stem tsa kankere ea matsoele ea ALDH-positive le tsela ea NF-κB.
• Vithamine C e ntlafatsa liphetoho tsa epigenetic tse bakoang ke 5-azacytidine le ho tšoaroa ha lisele tsa lisele tsa hepatocellular carcinoma cell lines HLE le Huh7.