Lijo bakeng sa Translocation-associated Renal Cell Carcinoma!

Selelekela

Lijo tse amanang le Translocation-associated Renal Cell Carcinoma li lokela ho etsoa ho motho ka mong hape li tlameha ho ikamahanya le maemo ha kalafo ea mofetše kapa liphatsa tsa lefutso tsa hlahala li fetoha. Ho iketsetsa motho le ho ikamahanya le maemo ho tlameha ho nahanela metsoako eohle e sebetsang kapa li-bioactive tse fumanehang lijong tse fapaneng mabapi le baeloji ea mofetše, liphatsa tsa lefutso, kalafo, maemo a bophelo le likhetho tsa lijo. Kahoo le hoja phepo e nepahetseng e le e 'ngoe ea liqeto tsa bohlokoa haholo tseo mokuli oa mofetše le motho ea kotsing ea mofetše a lokelang ho li etsa - mokhoa oa ho khetha lijo tseo u ka li jang ha se mosebetsi o bonolo.

Bakeng sa Translocation-associated Renal Cell Carcinoma na ho na le taba hore na motho o ja meroho, litholoana, linate, lipeo life?

Potso e atileng haholo ea phepo e botsoang ke bakuli ba mofets'e le batho ka bomong ba kotsing ea mofets'e ke - bakeng sa mofetše joalo ka Translocation-associated Renal Cell Carcinoma na ho na le taba hore na ke ja lijo life le tseo ke sa li jeng? Kapa haeba ke latela lijo tse thehiloeng limela na hoo ho lekane bakeng sa mofetše joalo ka Translocation-associated Renal Cell Carcinoma?

Mohlala, na ho na le taba hore Thistle ea meroho e jeoa haholo ha e bapisoa le Leek? Na ho na le phapang e teng haeba perekisi ea litholoana e ratoa ho feta kharenate? Hape haeba likhetho tse tšoanang li etsoa bakeng sa linate / peo e kang Walnut holim'a Cashew Nut le bakeng sa limela tse kang Pigeon Pea holim'a Common Pea. 'Me haeba seo ke se jang se le bohlokoa - joale motho o tseba joang lijo tse buelloang bakeng sa Translocation-associated Renal Cell Carcinoma 'me na ke karabo e tšoanang ho bohle ba nang le tlhahlobo e tšoanang kapa kotsi ea lefutso?

Ee! Lijo tseo u li jang ke tsa bohlokoa bakeng sa Translocation-associated Renal Cell Carcinoma!

Litlhahiso tsa lijo li ka 'na tsa se ke tsa tšoana ho bohle' me li ka fapana esita le bakeng sa tlhahlobo e tšoanang le kotsi ea lefutso.

Lijo tsohle (meroho, litholoana, linate, lipeo, li-pulses, oli joalo-joalo) le litlatsetso tsa phepo li entsoe ka metsoako e fetang e le 'ngoe e sebetsang ea molek'hule kapa bio-active ka tekanyo le bongata bo fapaneng. Sejo se seng le se seng se sebetsang se na le mokhoa o ikhethileng oa ts'ebetso - e ka bang ts'ebetso kapa ho thibela litsela tse fapaneng tsa biochemical. Lijo le li-supplement tse khothalletsoang habonolo ke tse sa bakeng keketseho ea limolek'hule tsa mofetše empa li li fokotsa. Ho seng joalo, lijo tseo ha lia lokela ho khothaletsoa. Lijo li na le metsoako e mengata e sebetsang - ka hona, ha u hlahloba lijo le li-supplement, u lokela ho nahana ka phello ea metsoako eohle e sebetsang ka bonngoe ho e-na le hore u nahane ka bonngoe.

Ka mohlala perekisi e na le metsoako e sebetsang Eugenol, Luteolin, Chlorogenic Acid, Linolenic Acid, Beta-carotene. 'Me kharenate e na le metsoako e sebetsang ea Corilagin, Eugenol, Luteolin, Linolenic Acid, Lutein le mohlomong tse ling.

Phoso e tloaelehileng e entsoeng ha ho etsoa qeto le ho khetha lijo tseo u ka li jang bakeng sa Translocation-associated Renal Cell Carcinoma - ke ho hlahloba feela metsoako e sebetsang e khethiloeng e fumanehang lijong le ho hlokomoloha tse ling. Hobane metsoako e fapaneng e sebetsang e fumanehang lijong e kanna ea ba le litlamorao tse fapaneng ho bakhanni ba mofetše - u ke ke ua khetha metsoako e sebetsang lijong le li-supplement bakeng sa ho etsa qeto ea phepo bakeng sa Translocation-associated Renal Cell Carcinoma.

EE – LIKHETHO TSA LIJO LI BOHLOKOA BAKENG SA KANKERE. LIQETO TSA PHEPO LI TLAMEHA HO NAHANA KA LITABA TSOHLE TSA LIJO.

Bokgoni bo Hlokahalang Bakeng sa Phepo ka Motho bakeng sa Translocation-associated Renal Cell Carcinoma?

Phepo ea motho ka mong bakeng sa mofets'e joalo ka Translocation-associated Renal Cell Carcinoma e na le lijo / litlatsetso tse khothaletsoang; lijo tse sa khothaletsoang tse nang le mohlala oa diresepe tse etelletsang pele tšebeliso ea lijo tse khothaletsoang. Mohlala oa phepo e nepahetseng o ka bonoa ho sena link tsa.

Ho etsa qeto ea hore na ke lijo life tse khothalelitsoeng kapa che ho rarahane haholo, ho hloka boiphihlelo ho Translocation-associated Renal Cell Carcinoma biology, saense ea lijo, liphatsa tsa lefutso, biochemistry hammoho le kutloisiso e ntle ea hore na liphekolo tsa mofetše li sebetsa joang le likotsi tse amanang le tsona tseo liphekolo li ka emisang ho sebetsa.

BONYENYANE BO TSEBO BOHLOKOA BAKENG SA PHEPO MOTHO BATHO BA KANKERE KE: BOLOJI YA KANKERE, SAENSE YA DIJO, DIPHEKO LA MOFEPO LE LIFUTSO.

Litšobotsi tsa mofetše joalo ka Translocation-associated Renal Cell Carcinoma

Lik'hemik'hale tsohle tse kang Translocation-associated Renal Cell Carcinoma li ka khetholloa ka sete e ikhethang ea litsela tsa biochemical - litsela tse saenneng tsa Translocation-associated Renal Cell Carcinoma. Litsela tsa biochemical tse kang Notch Signaling, DNA Repair, Chromatin Remodeling, Oncogenic Histone Methylation ke karolo ea tlhaloso ea signature ea Translocation-associated Renal Cell Carcinoma. Liphatsa tsa lefutso tsa mofetše oa motho ka mong li ka fapana, ka hona, tekeno ea bona ea mofetše e ka ikhetha.

Liphekolo tse sebetsang hantle bakeng sa Translocation-associated Renal Cell Carcinoma li hloka ho ela hloko mekhoa ea lik'hemik'hale e amanang le eona bakeng sa mokuli e mong le e mong oa mofetše le motho ea kotsing ea lefutso. Ka hona liphekolo tse fapaneng tse nang le mekhoa e fapaneng ea liketso li sebetsa hantle ho bakuli ba fapaneng. Ka mokhoa o ts'oanang le ka mabaka a ts'oanang lijo le li-supplement li hloka ho etsoa ka bomong bakeng sa motho ka mong. Kahoo lijo tse ling le li-supplement li khothaletsoa bakeng sa Translocation-associated Renal Cell Carcinoma ha u nka kalafo ea mofetše Sunitinib, 'me lijo tse ling le li-supplement ha li khothalletsoe.

Mehloli e kang cBioPortal 'me ba bang ba bangata ba fana ka lintlha tse sa tsejoeng tse tsoang litekong tsa bongaka bakeng sa matšoao ohle a mofetše. Lintlha tsena li na le lintlha tsa boithuto ba tleliniki joalo ka boholo ba sampole / palo ea bakuli, lihlopha tsa lilemo, bong, morabe, kalafo, sebaka sa tumor le liphetoho life kapa life tsa lefutso.

SMARCA4, TERT, ATM, ATRX le GRIN2A ke mefuta e kaholimo-limo e tlalehiloeng bakeng sa Translocation-associated Renal Cell Carcinoma. SMARCA4 e tlalehoa ho 20.0% ea bakuli ba baemeli ho pholletsa le liteko tsohle tsa bongaka. 'Me TERT e tlalehiloe ka 20.0%. Lintlha tse kopaneng tsa bakuli li akaretsa lilemo ho tloha ho. 27.6% ea data ea bakuli e tsejoa e le banna. The Translocation-e amanang le Renal Cell Carcinoma biology hammoho le liphatsa tsa lefutso tse tlalehiloeng hammoho li hlalosa palo ea batho ba emetseng mekhoa ea lik'hemik'hale ea kankere bakeng sa mofetše ona. Haeba liphatsa tsa lefutso tsa mofetše kapa liphatsa tsa lefutso tse kenyang kotsi le tsona li tsejoa, seo se lokela ho sebelisoa hape bakeng sa ho ja lijo.

LIKHETHO TSA PHEPO LI LOKELA HO TŠOANA LE MOTHO E MONG LE E MONG LE SAENYO EA MOTHO EA KANKERE.

Lijo le Tlatsetso bakeng sa Translocation-associated Renal Cell Carcinoma

Bakeng sa Bakuli ba Kankere

Bakuli ba mofetše ba nakong ea kalafo kapa ba tlhokomelong ea pholiso ba lokela ho etsa liqeto mabapi le lijo le li-supplement - bakeng sa lik'hilojule tse hlokahalang tsa lijo, ho laola litla-morao life kapa life tsa kalafo le bakeng sa taolo e ntlafetseng ea mofetše. Lijo tsohle tse thehiloeng ho limela ha li lekane, 'me ho khetha le ho etelletsa pele lijo tse ikhethileng le tse etselitsoeng kalafo e tsoelang pele ea mofets'e ho bohlokoa ebile ho rarahane. Mehlala ke ena e fanang ka litataiso bakeng sa ho etsa liqeto tsa phepo e nepahetseng.

Khetha Meroho THISTLE kapa LEEK?

Meroho Thistle e na le metsoako e mengata e sebetsang kapa bioactives tse kang Silibinin, Eugenol, Luteolin, Chlorogenic Acid, Lutein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Thistle e khothaletsoa bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo e tsoelang pele ea mofetše e le Sunitinib. Lebaka ke hobane Thistle e fetola litsela tseo tsa biochemical tse tlalehiloeng ka mahlale ho hlokomelisa phello ea Sunitinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa Leek ea meroho ke Eugenol, Luteolin, Chlorogenic Acid, Linolenic Acid, Lutein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Leek ha e khothalletsoe bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo ea mofetše e tsoelang pele e le Sunitinib hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofetše e se ke ea sebetsa kapa e se ke ea arabela hantle.

MERO E KHOTHATSO E KHOTHATSOE KA HO FETISISA LEEK BAKENG SA Translocation-associated Renal Cell Carcinoma LE PHEKO Sunitinib.

Khetha Litholoana POMEGRANATE kapa PEACH?

Litholoana Kharenate e na le metsoako e mengata e sebetsang kapa bioactives tse kang Corilagin, Eugenol, Luteolin, Linolenic Acid, Lutein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Kharenate e khothaletsoa bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo e tsoelang pele ea mofetše e le Sunitinib. Sena se bakoa ke hore kharenate e fetola litsela tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Sunitinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana Peach ke Eugenol, Luteolin, Chlorogenic Acid, Linolenic Acid, Beta-carotene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Peach ha e khothalletsoe bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo e tsoelang pele ea mofets'e e le Sunitinib hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

THOLOANA POMEGRANATE E KHOTHATSOE KA HO FETISISA PEACH BAKENG SA Translocation-associated Renal Cell Carcinoma LE PHEKO Sunitinib.

Khetha Nut WALNUT kapa CASHEW NUT?

Walnut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Carvacrol, Eugenol, Luteolin, Chlorogenic Acid, Juglone. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Walnut e khothaletsoa bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo e tsoelang pele ea mofetše e le Sunitinib. Lebaka ke hobane Walnut e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Sunitinib.

Tse ling tsa metsoako e sebetsang kapa bioactives ho Cashew Nut ke Eugenol, Chlorogenic Acid, Anacardic Acid, Linolenic Acid, Lutein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Notch Signaling le tse ling. Cashew Nut ha e khothalletsoe bakeng sa Translocation-associated Renal Cell Carcinoma ha kalafo e tsoelang pele ea mofets'e e le Sunitinib hobane e fetola litsela tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

WALNUT E KHOTHATSOE HO HOLIMO LE NAKO EA K'HASHEW BAKENG SA Translocation-associated Renal Cell Carcinoma LE PHEKO Sunitinib.

Bakeng sa Batho ba nang le Kotsi ea Liphatsa tsa Kankere

Potso e botsoang ke batho ba nang le kotsi ea lefutso ea Translocation-associated Renal Cell Carcinoma kapa nalane ea lelapa ke "Ke Lokela ho Ja Eng e sa Tšoaneng le Pele?" le kamoo ba lokelang ho khetha lijo le li-supplement bakeng sa ho laola likotsi tsa lefu lena. Kaha bakeng sa kotsi ea mofets'e ha ho letho le ka etsoang mabapi le kalafo - liqeto tsa lijo le li-supplement li fetoha tsa bohlokoa mme e 'ngoe ea lintho tse seng kae tse ka etsoang. Lijo tsohle tse thehiloeng limela ha li lekane 'me li ipapisitse le liphatsa tsa lefutso le mokhoa oa ho saena - khetho ea lijo le li-supplement li lokela ho etsoa ke motho ka mong.

Khetha Meroho ea BRUSSEL SPOUTS kapa MALABAR SPINACH?

Meroho ea Brussel Sprouts e na le lisebelisoa tse ngata tse sebetsang kapa li-bioactive tse kang Curcumin, Indole-3-carbinol, Lupeol, Formononetin, Daidzein. Lithako tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Tokiso ea DNA, Cell Cycle, Cell Cycle Checkpoints le MYC Signaling le tse ling. Brussel Sprouts e kgothaletswa bakeng sa kotsi ya Translocation-associated Renal Cell Carcinoma ha kotsi ea lefutso e amanang le ATM. Lebaka ke hobane Brussel Sprouts e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho Malabar Spinach ke Apigenin, Curcumin, Quercetin, Lupeol, Formononetin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka DNA Repair le tse ling. Malabar Spinach ha e khothalletsoe ha kotsi ea Translocation-associated Renal Cell Carcinoma e amahanngoa le kotsi ea liphatsa tsa lefutso ke ATM hobane e eketsa litsela tsa ho saena.

LITLHAKISO TSA MEROHO BRUSSEL E KHOTHATSOE HO PHETHA MALABAR SPINACH BAKENG SA ATM genetic RISK OF CANCER.

Khetha Fruit NANCE kapa PUMMELO?

Litholoana tsa Nance li na le lisebelisoa tse ngata tse sebetsang kapa li-bioactive tse kang Apigenin, Curcumin, Formononetin, Lupeol, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Cell Cycle, Hypoxia le P53 Signaling le tse ling. Nance e buelloa bakeng sa kotsi ea Translocation-associated Renal Cell Carcinoma ha kotsi ea lefutso e amanang le ATM. Lebaka ke hore Nance e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives litholoana Pummelo ke Apigenin, Curcumin, Quercetin, Formononetin, Lupeol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka DNA Repair le tse ling. Pummelo ha e khothalletsoe ha kotsi ea Translocation-associated Renal Cell Carcinoma e amahanngoa le kotsi ea lefutso e le ATM hobane e eketsa litsela tsa ho saena.

THOLOANA NANCE E KHOTHATSOA HO FETISISA PUMMELO BAKENG SA ATM genetic KOTSI EA KANSE.

Khetha Nut BUTTERNUT kapa CHESTNUT?

Butternut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Apigenin, Curcumin, Lupeol, Formononetin, Daidzein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang DNA Repair, Cell Cycle, Hypoxia le MYC Signaling le tse ling. Butternut e kgothaletswa bakeng sa kotsi ya Translocation-associated Renal Cell Carcinoma ha kotsi ea lefutso e amanang le ATM. Lebaka ke hobane Butternut e eketsa litsela tsa biochemical tse khahlano le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives ka Chestnut ke Apigenin, Curcumin, Formononetin, Lupeol, Ellagic Acid. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka DNA Repair le tse ling. Chestnut ha e khothalletsoe ha kotsi ea Translocation-associated Renal Cell Carcinoma e amahanngoa le kotsi ea liphatsa tsa lefutso ke ATM hobane e eketsa litsela tsa ho saena.

BUTTERNUT E KHOTHATSOA HO FETISISA CHESTNUT BAKENG SA ATM genetic KOTSI EA KANSE.

Ha re phethela

Lijo le Lisebelisoa tse khethiloeng ke liqeto tsa bohlokoa bakeng sa mofetše joalo ka Translocation-associated Renal Cell Carcinoma. Bakuli ba Renal Cell Carcinoma e amanang le Translocation le batho ba nang le kotsi ea lefutso ba lula ba e-na le potso ena: "Ke lijo life le li-supplement tsa phepo tse khothalletsoang ho 'na le tse sa buelloang?" Ho na le tumelo e tloaelehileng eo e leng maikutlo a fosahetseng a hore lijo tsohle tse thehiloeng limela li ka ba molemo kapa che empa li ke ke tsa e-ba kotsi. Lijo tse ling le li-supplement li ka kena-kenana le phekolo ea mofetše kapa tsa khothalletsa bakhanni ba limolek'hule tsa mofetše.

Ho na le mefuta e fapaneng ea matšoao a mofets'e joalo ka Translocation-associated Renal Cell Carcinoma, e 'ngoe le e' ngoe e na le liphatsa tsa lefutso tse fapaneng tsa tumor tse nang le mefuta e meng ea genomic ho motho ka mong. Ho feta moo kalafo e 'ngoe le e' ngoe ea mofetše le chemotherapy e na le mokhoa o ikhethileng oa ts'ebetso. Sejo se seng le se seng joalo ka Thistle se na le li-bioactive tse fapaneng ka bongata bo fapaneng, tse nang le tšusumetso litseleng tse fapaneng le tse ikhethileng tsa biochemical. Tlhaloso ea phepo e nepahetseng ke likhothaletso tsa motho ka mong bakeng sa sesupo sa mofetše, kalafo, liphatsa tsa lefutso, mokhoa oa bophelo le lintlha tse ling. Liqeto tsa phepo e nepahetseng bakeng sa mofetše li hloka tsebo ea biology ea mofets'e, mahlale a lijo le kutloisiso ea liphekolo tse fapaneng tsa chemotherapy. Qetellong ha ho e-na le liphetoho tsa phekolo kapa li-genomics tse ncha li khetholloa - phepo e nepahetseng e hloka ho hlahlojoa bocha.

Tharollo ea motho ka mong ea phepo e nepahetseng ea addon e etsa hore ho etsa liqeto ho be bonolo le ho tlosa likhakanyo tsohle ho araba potso e reng, "Ke lijo life tseo ke lokelang ho li khetha kapa ho se khethe bakeng sa Translocation-associated Renal Cell Carcinoma?". Sehlopha sa li-addon tse nang le taeo e mengata se kenyelletsa lingaka tsa mofetše, bo-ramahlale ba bongaka, baenjiniere ba mananeo le bo-ramahlale ba data.

References

• Msk Impact 2017
• Boemo bo feto-fetohang ba mofetše oa metastatic bo senotsoe ho tsoa ho tatellano ea kliniki ea bakuli ba 10,000.
• Eugenol e thibela Kankere Stem Cell ka ho senyeha ha β-catenin ka N-terminal Ser37 phosphorylation-an in vivo le in vitro liteko tsa tekolo.
• Luteolin e hatella tsoelo-pele ea mofetše oa mala ka ho khutlisa phetoho ea epithelial-mesenchymal ka ho hatella tsela ea pontšo ea Notch.
• Retinoic acid receptor β e matlafalitse phello ea lisele tse khahlanong le mofetše tsa β-carotene ka polelo e theolelang ea taolo ea delta-like 1 homologue liseleng tsa neuroblastoma tsa motho.
• Corilagin e hatella tsoelo-pele ea cholangiocarcinoma ka tsela ea Notch ea ho bonts'a in vitro le in vivo.
• Hesperetin, pheko e ka bang teng bakeng sa mofetše oa kankere.
• Thibelo ea Silybin-mediated ea pontšo ea Notch e fana ka ts'ebetso ea antitumor liseleng tsa motho tsa hepatocellular carcinoma.
• Carvacrol Induced Program Cell Cell Death le Cell Cycle Cycle Ho tšoaroa Liseleng tsa Kankere ea Botho e Ikemetseng ea Androgen ka Thibelo ea Letšoao la Notch.
• Paederia foetida e susumetsa ts'ebetso ea anticancer ka ho fetola li-enzyme tsa phetoho ea chromatin le ho fetola liphatsa tsa lefutso tsa pro-inflammatory cytokine liseleng tsa mofetše oa tšoelesa ea senya.
• Brassinin e etsa hore ho ts'oaroe karolo ea G1 ka keketseho ea p21 le p27 ka ho thibela phosphatidylinositol 3-kinase tsela ea ponts'o liseleng tsa mofetše oa mala.
• Formononetin e hatella ho ata ha mofetše oa matšoafo oa sele e seng e nyane ka ho kenngoa ha ho ts'oaroa ha cell cycle le apoptosis.
• Asiti ea Gallic e baka tšenyo ea DNA mme e hatella tlhahiso ea liphatsa tsa lefutso tsa DNA ho mofetše oa tšoelesa ea senya ea PC-3.