Lijo tsa Medulloblastoma!

Selelekela

Lijo tsa Medulloblastoma li lokela ho etsoa ho motho ka mong hape li lokela ho ikamahanya le maemo ha kalafo ea mofetše kapa liphatsa tsa lefutso tsa tumor li fetoha. Ho iketsetsa motho le ho ikamahanya le maemo ho tlameha ho nahanela metsoako eohle e sebetsang kapa li-bioactive tse fumanehang lijong tse fapaneng mabapi le baeloji ea mofetše, liphatsa tsa lefutso, kalafo, maemo a bophelo le likhetho tsa lijo. Kahoo le hoja phepo e nepahetseng e le e 'ngoe ea liqeto tsa bohlokoa haholo tseo mokuli oa mofetše le motho ea kotsing ea mofetše a lokelang ho li etsa - mokhoa oa ho khetha lijo tseo u ka li jang ha se mosebetsi o bonolo.

Medulloblastoma ke mofuta oa hlahala ea boko e sa tloaelehang, e nang le mofetše e hlahang cerebellum (thito ea boko), joalo ka ha e atile haholo ho bana ho feta batho ba baholo. Hlahala e hōla ka potlako ’me e ka namela libakeng tse ling tsa boko le lesapo la mokokotlo. Matšoao a medulloblastoma a kenyelletsa hlooho e opang, ho tsekela, ho nyekeloa ke pelo le ho hlatsa, mokhathala, litaba tse leka-lekaneng, ho fetoha ha pono, bothata ba ho tsamaea, bohloko ba morao, mathata a ho ntša metsi kapa mala. Lisosa tsa medulloblastoma ha li utloisisoe ka botlalo, empa liphetoho tsa liphatsa tsa lefutso tse kang BRCA1 le BRCA2 li ka bapala karolo. Likhetho tsa kalafo bakeng sa medulloblastoma li kenyelletsa opereishene, kalafo ea radiation, le chemotherapy, e etselitsoeng boemo bo ikhethileng ba motho. Sekhahla le sekhahla sa ho phela ho batho ba baholo ba nang le medulloblastoma se fapane le sa bana. Sekhahla sa lilemo tse 5 sa ho phela ha medulloblastoma se feta 70%. Bophelo ka mor'a medulloblastoma bo hloka tlhokomelo e haufi le ho latela

Bakeng sa Medulloblastoma na ho na le taba hore na motho o ja meroho, litholoana, linate, lipeo life?

Potso e atileng haholo ea phepo e botsoang ke bakuli ba mofets'e le batho ka bomong ba kotsing ea mofets'e ke - bakeng sa mofetše o kang Medulloblastoma na ho na le taba hore na ke ja lijo life le tseo ke sa li jeng? Kapa haeba ke latela lijo tse thehiloeng ho semela na ho lekane bakeng sa mofetše joalo ka Medulloblastoma?

Ka mohlala, na ho na le taba hore sepinachi sa New Zealand se jeoa haholo ha se bapisoa le Jerusalem Artichoke? Na ho na le phapang e teng haeba litholoana tsa Pummelo li ratoa ho feta Red Raspberry? Hape haeba ho etsoa khetho e tšoanang bakeng sa linate/lipeo tse kang Butternut holim'a Chestnut ea Europe le bakeng sa limela tse kang Broad Bean holim'a Hyacinth Bean. 'Me haeba seo ke se jang se bohlokoa - joale motho o tseba joang lijo tse buelloang bakeng sa Medulloblastoma mme ke karabo e tšoanang bakeng sa bohle ba nang le tlhahlobo e tšoanang kapa kotsi ea lefutso?

Ee! Lijo tseo u li jang li bohlokoa bakeng sa Medulloblastoma!

Litlhahiso tsa lijo li ka 'na tsa se ke tsa tšoana ho bohle' me li ka fapana esita le bakeng sa tlhahlobo e tšoanang le kotsi ea lefutso.

Lijo tsohle (meroho, litholoana, linate, lipeo, li-pulses, oli joalo-joalo) le litlatsetso tsa phepo li entsoe ka metsoako e fetang e le 'ngoe e sebetsang ea molek'hule kapa bio-active ka tekanyo le bongata bo fapaneng. Sejo se seng le se seng se sebetsang se na le mokhoa o ikhethileng oa ts'ebetso - e ka bang ts'ebetso kapa ho thibela litsela tse fapaneng tsa biochemical. Lijo le li-supplement tse khothalletsoang habonolo ke tse sa bakeng keketseho ea limolek'hule tsa mofetše empa li li fokotsa. Ho seng joalo, lijo tseo ha lia lokela ho khothaletsoa. Lijo li na le metsoako e mengata e sebetsang - ka hona, ha u hlahloba lijo le li-supplement, u lokela ho nahana ka phello ea metsoako eohle e sebetsang ka bonngoe ho e-na le hore u nahane ka bonngoe.

Ka mohlala Pummelo e na le metsoako e sebetsang Quercetin, Curcumin, Isoliquiritigenin, Apigenin, Lycopene. 'Me Raspberry e khubelu e na le metsoako e sebetsang ea Quercetin, Ellagic Acid, Curcumin, Isoliquiritigenin, Formononetin le mohlomong tse ling.

Phoso e tloaelehileng e entsoeng ha ho etsoa qeto le ho khetha lijo tse jeoang bakeng sa Medulloblastoma - ke ho hlahloba feela metsoako e sebetsang e khethiloeng e fumanehang lijong le ho hlokomoloha tse ling kaofela. Hobane metsoako e fapaneng e sebetsang e fumanehang lijong e kanna ea ba le litlamorao tse fapaneng ho bakhanni ba mofetše - u ke ke ua khetha metsoako e sebetsang lijong le litlatsetso bakeng sa ho etsa qeto ea phepo bakeng sa Medulloblastoma.

EE – LIKHETHO TSA LIJO LI BOHLOKOA BAKENG SA KANKERE. LIQETO TSA PHEPO LI TLAMEHA HO NAHANA KA LITABA TSOHLE TSA LIJO.

Tsebo e Hlokahalang Bakeng sa Phepo ea Boipheliso bakeng sa Medulloblastoma?

Phepo ea motho ka mong bakeng sa mofetše joalo ka Medulloblastoma e na le lijo / li-supplement tse khothalelitsoeng; lijo tse sa khothaletsoang tse nang le mohlala oa diresepe tse etelletsang pele tšebeliso ea lijo tse khothaletsoang. Mohlala oa phepo e nepahetseng o ka bonoa ho sena link tsa.

Ho etsa qeto ea hore na ke lijo life tse khothalelitsoeng kapa che ho rarahane haholo, ho hloka boiphihlelo ho baeloji ea Medulloblastoma, mahlale a lijo, liphatsa tsa lefutso, biochemistry hammoho le kutloisiso e ntle ea hore na kalafo ea mofets'e e sebetsa joang le bofokoli bo amanang le bona boo kalafo e ka emisang ho sebetsa.

BONYENYANE BO TSEBO BOHLOKOA BAKENG SA PHEPO MOTHO BATHO BA KANKERE KE: BOLOJI YA KANKERE, SAENSE YA DIJO, DIPHEKO LA MOFEPO LE LIFUTSO.

Litšobotsi tsa mofets'e joalo ka Medulloblastoma

Lik'hemik'hale tsohle tse kang Medulloblastoma li ka khetholloa ka mokhoa o ikhethang oa litsela tsa lik'hemik'hale - litsela tsa ho saena tsa Medulloblastoma. Litsela tsa biochemical tse kang DNA Repair, Angiogenesis, Oncogenic Histone Methylation, Epithelial to Mesenchymal Transition ke karolo ea tlhaloso ea signature ea Medulloblastoma. Liphatsa tsa lefutso tsa mofetše oa motho ka mong li ka fapana, ka hona, tekeno ea bona ea mofetše e ka ikhetha.

Liphekolo tse sebetsang hantle bakeng sa Medulloblastoma li hloka ho ela hloko mekhoa ea lik'hemik'hale e amanang le eona bakeng sa mokuli e mong le e mong oa mofetše le motho ea kotsing ea lefutso. Ka hona liphekolo tse fapaneng tse nang le mekhoa e fapaneng ea liketso li sebetsa hantle ho bakuli ba fapaneng. Ka mokhoa o ts'oanang le ka mabaka a ts'oanang lijo le li-supplement li hloka ho etsoa ka bomong bakeng sa motho ka mong. Kahoo lijo tse ling le li-supplement li khothaletsoa bakeng sa Medulloblastoma ha u nka kalafo ea mofetše Temozolomide, 'me lijo tse ling le li-supplement ha li khothalletsoe.

Mehloli e kang cBioPortal 'me ba bang ba bangata ba fana ka lintlha tse sa tsejoeng tse tsoang litekong tsa bongaka bakeng sa matšoao ohle a mofetše. Lintlha tsena li na le lintlha tsa boithuto ba tleliniki joalo ka boholo ba sampole / palo ea bakuli, lihlopha tsa lilemo, bong, morabe, kalafo, sebaka sa tumor le liphetoho life kapa life tsa lefutso.

PTCH1, TERT, DDX3X, KMT2D le CTNNB1 ke liphatsa tsa lefutso tse tlalehiloeng ka holimo bakeng sa Medulloblastoma. PTCH1 e tlalehoa ho 6.3% ea bakuli ba baemeli ho pholletsa le liteko tsohle tsa bongaka. 'Me TERT e tlalehiloe ka 6.2%. Palo e kopaneng ea litaba tsa bakuli ba lilemo tse tsoang ho 1 ho isa ho 50. 62.3 % ea lintlha tsa mokuli e tsejoa e le banna. Biology ea Medulloblastoma hammoho le liphatsa tsa lefutso tse tlalehiloeng hammoho li hlalosa palo ea batho ba emelang mekhoa ea lik'hemik'hale tsa mofetše. Haeba liphatsa tsa lefutso tsa mofetše kapa liphatsa tsa lefutso tse kenyang kotsi le tsona li tsejoa, seo se lokela ho sebelisoa hape bakeng sa ho ja lijo.

LIKHETHO TSA PHEPO LI LOKELA HO TŠOANA LE MOTHO E MONG LE E MONG LE SAENYO EA MOTHO EA KANKERE.

Lijo le Tlatsetso ea Medulloblastoma

Bakeng sa Bakuli ba Kankere

Bakuli ba mofetše ba nakong ea kalafo kapa ba tlhokomelong ea pholiso ba lokela ho etsa liqeto mabapi le lijo le li-supplement - bakeng sa lik'hilojule tse hlokahalang tsa lijo, ho laola litla-morao life kapa life tsa kalafo le bakeng sa taolo e ntlafetseng ea mofetše. Lijo tsohle tse thehiloeng ho limela ha li lekane, 'me ho khetha le ho etelletsa pele lijo tse ikhethileng le tse etselitsoeng kalafo e tsoelang pele ea mofets'e ho bohlokoa ebile ho rarahane. Mehlala ke ena e fanang ka litataiso bakeng sa ho etsa liqeto tsa phepo e nepahetseng.

Khetha Meroho NEW ZEALAND SPINACH kapa JERUSALEM ARTICHOKE?

Meroho ea New Zealand Spinach e na le metsoako e mengata e sebetsang kapa bioactives tse kang Quercetin, Curcumin, Isoliquiritigenin, Apigenin, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Growth Factor Signaling, Hypoxia, NFKB Signaling le Focal Adhesion le tse ling. New Zealand Spinach e khothaletsoa bakeng sa Medulloblastoma ha kalafo e tsoelang pele ea mofets'e e le Temozolomide. Sena ke hobane Spinach ea New Zealand e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Temozolomide.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho ea Jerusalema Artichoke ke Curcumin, Isoliquiritigenin, Apigenin, Formononetin, Phloretin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Tokiso ea DNA le TGFB Signaling le tse ling. Jerusalem Artichoke ha e khothalletsoe bakeng sa Medulloblastoma ha kalafo e tsoelang pele ea mofets'e e le Temozolomide hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

MOROO OA NEW ZEALAND SPINACH E KHOTHATSOE HO FETA JERUSALEMA ARTICHOKE BAKENG SA Medulloblastoma LE PHEKO Temozolomide.

Khetha Fruit RED RASPBERRY kapa PUMMELO?

Litholoana Raspberry Red e na le metsoako e mengata e sebetsang kapa bioactives tse kang Quercetin, Ellagic Acid, Curcumin, Isoliquiritigenin, Formononetin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang MAPK Signaling, NFKB Signaling, Focal Adhesion le Oxidative Stress le tse ling. Raspberry e khubelu e khothalletsoa Medulloblastoma ha phekolo ea kankere e tsoelang pele e le Temozolomide. Sena ke hobane Raspberry e khubelu e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Temozolomide.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana Pummelo ke Quercetin, Curcumin, Isoliquiritigenin, Apigenin, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka DNA Repair le Oxidative Stress le tse ling. Pummelo ha e khothalletsoe bakeng sa Medulloblastoma ha kalafo ea mofets'e e ntse e tsoela pele e le Temozolomide hobane e fetola litsela tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

RASPBERRY YA THOLOANA E KHIBIDU E KHOTHWA HO FETISISA PUMMELO BAKENG SA Medulloblastoma LE PHEKO Temozolomide.

Khetha Nut BUTTERNUT kapa EUROPEAN CHESTNUT?

Butternut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Curcumin, Isoliquiritigenin, Apigenin, Lycopene, Formononetin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang MAPK Signaling, DNA Repair, NFKB Signaling le Focal Adhesion le tse ling. Butternut e khothaletsoa bakeng sa Medulloblastoma ha kalafo e tsoelang pele ea mofets'e e le Temozolomide. Sena ke hobane Butternut e fetola litsela tseo tsa biochemical tse tlalehiloeng ka saense ho hlokomelisa phello ea Temozolomide.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa Chestnut ea Europe ke Quercetin, Ellagic Acid, Curcumin, Isoliquiritigenin, Apigenin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Tokiso ea DNA le TGFB Signaling le tse ling. European Chestnut ha e khothalletsoe bakeng sa Medulloblastoma ha kalafo e tsoelang pele ea mofets'e e le Temozolomide hobane e fetola litsela tseo tsa biochemical tse etsang hore kalafo ea mofets'e e hane kapa e se ke ea arabela hantle.

BUTTERNUT E KHOTHATSOE HO FETA CHESTNUT EA EUROPE BAKENG SA Medulloblastoma LE PHEKO Temozolomide.

Bakeng sa Batho ba nang le Kotsi ea Liphatsa tsa Kankere

Potso e botsoang ke batho ba nang le kotsi ea lefutso ea Medulloblastoma kapa nalane ea lelapa ke "Ke Lokela ho Ja Eng e Fapaneng le Pele?" le kamoo ba lokelang ho khetha lijo le li-supplement bakeng sa ho laola likotsi tsa lefu lena. Kaha bakeng sa kotsi ea mofets'e ha ho letho le ka etsoang mabapi le kalafo - liqeto tsa lijo le li-supplement li fetoha tsa bohlokoa 'me e le e' ngoe ea lintho tse fokolang haholo tse ka etsoang. Lijo tsohle tse thehiloeng ho limela ha li lekane 'me li ipapisitse le liphatsa tsa lefutso le mokhoa oa ho saena - khetho ea lijo le li-supplement li lokela ho etsoa ke motho ka mong.

Khetha Vegetable GIANT BUTTERBUR kapa OSTRICH FERN?

Vegetable Giant Butterbur e na le metsoako e mengata e sebetsang kapa bioactives tse kang Curcumin, Apigenin, Formononetin, Lupeol, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang RAS-RAF Signaling, JAK-STAT Signaling, Oncogenic Cancer Epigenetics le PI3K-AKT-MTOR Signaling le tse ling. Giant Butterbur e khothalletsoa kotsi ea Medulloblastoma ha kotsi ea lefutso e amanang le CTNNB1. Sena ke hobane Giant Butterbur e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho ea Ostrich Fern ke Curcumin, Apigenin, Formononetin, Lupeol, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Oncogenic Cancer Epigenetics, WNT Beta Catenin Signaling le Stem Cell Signaling le tse ling. Ostrich Fern ha e khothalletsoe ha kotsi ea Medulloblastoma e amahanngoa le kotsi ea lefutso e le CTNNB1 hobane e eketsa litsela tsa eona.

BUTERBURU E KHOLO EA MERO E KHOTHATSOE HO FEELA OSTRICH FERN BAKENG SA CTNNB1 KOTSI EA LITŠOANTŠISO EA KANKERE.

Khetha Litholoana tsa NANCE kapa SUMMER GRAPE?

Litholoana tsa Nance li na le metsoako e mengata e sebetsang kapa li-bioactive tse kang Curcumin, Apigenin, Formononetin, Betulinic Acid, Lupeol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang RAS-RAF Signaling, JAK-STAT Signaling, Oncogenic Cancer Epigenetics le PI3K-AKT-MTOR Signaling le tse ling. Nance e khothaletsoa bakeng sa kotsi ea Medulloblastoma ha kotsi ea lefutso e amanang le CTNNB1. Lebaka ke hore Nance e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives litholoana tsa Morara oa Lehlabula ke Curcumin, Apigenin, Formononetin, Lupeol, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Oncogenic Cancer Epigenetics, WNT Beta Catenin Signaling le Stem Cell Signaling le tse ling. Morara wa Lehlabula ha o kgothaletswe ha kotsi ya Medulloblastoma e amahanngwa le kotsi ya lefutso e le CTNNB1 hobane e eketsa mesaeno ya yona.

THOLOANA NANCE E KHOTHATSOA HO FETISISA MORARA WA LEHLABULA BAKENG SA CTNNB1 Genese RISK EA KANKERE.

Khetha Nut CHIA kapa WALNUT ea JAPANESE?

Chia e na le metsoako e mengata e sebetsang kapa li-bioactive tse kang Curcumin, Apigenin, Formononetin, Lupeol, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Cell Cycle Checkpoints, RAS-RAF Signaling, Oncogenic Cancer Epigenetics le PI3K-AKT-MTOR Signaling le tse ling. Chia e buelloa bakeng sa kotsi ea Medulloblastoma ha kotsi ea lefutso e amanang le CTNNB1. Sena ke hobane Chia e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona.

Tse ling tsa metsoako e sebetsang kapa bioactives ka Walnut ea Japane ke Curcumin, Apigenin, Formononetin, Lupeol, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Oncogenic Cancer Epigenetics, WNT Beta Catenin Signaling le Stem Cell Signaling le tse ling. Japanese Walnut ha e khothalletsoe ha kotsi ea Medulloblastoma e amahanngoa le kotsi ea liphatsa tsa lefutso ke CTNNB1 hobane e eketsa litsela tsa ho saena.

CHIA E KHOTHALETSOE HO PHAHAMA WALNUT YA JAPANESE BAKENG SA CTNNB1 genetic RISK YA KANKERE.

Ha re phethela

Lijo le li-Supplement tse khethiloeng ke liqeto tsa bohlokoa bakeng sa mofetše joalo ka Medulloblastoma. Bakuli ba Medulloblastoma le batho ba nang le kotsi ea liphatsa tsa lefutso ba lula ba e-na le potso ena: "Ke lijo life le li-supplement tsa phepo tse khothalletsoang ho 'na le tse sa buelloang?" Ho na le tumelo e tloaelehileng eo e leng maikutlo a fosahetseng a hore lijo tsohle tse thehiloeng limela li ka ba molemo kapa che empa li ke ke tsa e-ba kotsi. Lijo tse ling le li-supplement li ka kena-kenana le phekolo ea mofetše kapa tsa khothalletsa bakhanni ba limolek'hule tsa mofetše.

Ho na le mefuta e fapaneng ea matšoao a mofets'e joalo ka Medulloblastoma, e 'ngoe le e' ngoe e na le liphatsa tsa lefutso tse fapaneng tse nang le mefuta e fapaneng ea genomic ho motho ka mong. Ho feta moo kalafo e 'ngoe le e' ngoe ea mofetše le chemotherapy e na le mokhoa o ikhethileng oa ts'ebetso. Sejo se seng le se seng joalo ka New Zealand Spinach se na le li-bioactive tse fapaneng ka bongata bo fapaneng, tse nang le tšusumetso litseleng tse fapaneng le tse ikhethileng tsa lik'hemik'hale tsa biochemical. Tlhaloso ea phepo e nepahetseng ke likhothaletso tsa motho ka mong bakeng sa sesupo sa mofetše, kalafo, liphatsa tsa lefutso, mokhoa oa bophelo le lintlha tse ling. Liqeto tsa phepo e nepahetseng bakeng sa mofetše li hloka tsebo ea biology ea mofets'e, mahlale a lijo le kutloisiso ea liphekolo tse fapaneng tsa chemotherapy. Qetellong ha ho e-na le liphetoho tsa phekolo kapa li-genomics tse ncha li khetholloa - phepo e nepahetseng e hloka ho hlahlojoa bocha.

Tharollo ea motho ka mong ea phepo ea addon e etsa hore ho be bonolo ho etsa liqeto mme e tlose mehopolo eohle ea ho araba potso e reng, "Ke lijo life tseo ke lokelang ho li khetha bakeng sa Medulloblastoma?". Sehlopha sa li-addon tse nang le taeo e mengata se kenyelletsa lingaka tsa mofetše, bo-ramahlale ba bongaka, baenjiniere ba mananeo le bo-ramahlale ba data.

References

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• Eibl T et al, Botsofali (Albany NY), 2021
• https://my.clevelandclinic.org/health/diseases/22591-medulloblastoma
• https://www.cancer.gov/rare-brain-spine-tumor/tumors/medulloblastoma#:~:text=Medulloblastoma%20Prognosis,how%20they%20respond%20to%20treatment