Lijo tsa Waldenstrom Macroglobulinemia!

Selelekela

Lijo tsa Waldenstrom Macroglobulinemia li lokela ho etsoa ka bomong bakeng sa motho ka mong hape li tlameha ho ikamahanya le maemo ha kalafo ea mofetše kapa liphatsa tsa lefutso tsa hlahala li fetoha. Ho iketsetsa motho le ho ikamahanya le maemo ho tlameha ho nahanela metsoako eohle e sebetsang kapa li-bioactive tse fumanehang lijong tse fapaneng mabapi le baeloji ea mofetše, liphatsa tsa lefutso, kalafo, maemo a bophelo le likhetho tsa lijo. Kahoo le hoja phepo e nepahetseng e le e 'ngoe ea liqeto tsa bohlokoa haholo tseo mokuli oa mofetše le motho ea kotsing ea mofetše a lokelang ho li etsa - mokhoa oa ho khetha lijo tseo u ka li jang ha se mosebetsi o bonolo.

Waldenstrom macroglobulinemia ke lefu le sa tloaelehang la mali le sa foleng le amang lisele tse tšoeu tsa mali (lymphocyte). Ke mofuta oa non-Hodgkin lymphoma. E boetse e bitsoa lymphoplasmacytic lymphoma. Ke kankere ea mali e sa tloaelehang, e ntseng e hōla butle, e bonahalang ka ho ba teng ha tekanyo e phahameng ea macroglobin (immunoglobin M [IgM]. Protheine ea M e tenya mali, e ama ho phalla ha mali methapong e menyenyane ea mali, boemo bo sa tloaelehang bo ikhethang. Ho Waldenstrom macroglobulinemia e bitsoang hyper viscosity syndrome. le ho thibela lisele tse tloaelehileng tsa mali tse lebisang ho fokotseng ho sebetsa ha lisele tse khubelu tsa mali, li-neutrophils le li-platelet le ho baka maemo a cytopenic joalo ka anemia, neutropenia, le thrombocytopenia. ea Waldenstrom macroglobulinemia e akarelletsa mokhathala, feberu, ho felloa ke takatso ea lijo, ho fufuleloa bosiu, bofokoli, ho tsoa mali ka nko, pono e lerootho, sebete se atolositsoeng kapa spleen le lymph nodes tse ruruhileng. E 'ngoe ea lisosa tse ka sehloohong tsa Waldenstrom macroglobulinemia ho 90% ea bakuli ba fumanoeng ke phetoho ea lefutso la MYD88. Sekhahla sa ho phela sa lilemo tse 5 bakeng sa bakuli ba fumanoeng ba e-na le boemo bona ke 78% (American Cancer Society, 2022). Mekhoa ea phekolo bakeng sa Waldenstrom macroglobulinemia e kenyelletsa plasmapheresis (phapanyetsano ea plasma), chemotherapy, immunotherapy, phekolo e lebisitsoeng, phekolo ea mahlaseli le ho fetisetsa lisele tsa stem kapa moko oa masapo. Ho feta moo, phepo e nepahetseng (lijo le litlatsetso tsa tlhaho) tse tsamaellanang le mofetše le maemo a kalafo li ka ntlafatsa bophelo bo botle ba bakuli.

Bakeng sa Waldenstrom Macroglobulinemia na ho na le taba hore na motho o ja meroho, litholoana, linate, lipeo life?

Potso e atileng haholo ea phepo e botsoang ke bakuli ba mofets'e le batho ka bomong ba kotsing ea mofets'e ke - bakeng sa mofetše o kang Waldenstrom Macroglobulinemia na ho na le taba hore na ke ja lijo life le tseo ke sa li jeng? Kapa haeba ke latela lijo tse thehiloeng limela na hoo ho lekane bakeng sa mofetše joaloka Waldenstrom Macroglobulinemia?

Ka mohlala, na ho na le taba hore makhasi a Chicory a jeoa haholo ha a bapisoa le Mariha Squash? Na ho na le phapang e teng haeba litholoana tsa Grapefruit li ratoa ho feta Pear? Hape haeba khetho e tšoanang e etsoa bakeng sa linate/peo e kang Walnut holim'a Walnut ea Japane le bakeng sa limela tse kang Cowpea holim'a White Lupine. 'Me haeba seo ke se jang se bohlokoa - joale motho o tseba joang lijo tse buelloang bakeng sa Waldenstrom Macroglobulinemia mme ke karabo e tšoanang bakeng sa bohle ba nang le tšoaetso e tšoanang kapa kotsi ea lefutso?

Ee! Lijo tseo u li jang li bohlokoa bakeng sa Waldenstrom Macroglobulinemia!

Litlhahiso tsa lijo li ka 'na tsa se ke tsa tšoana ho bohle' me li ka fapana esita le bakeng sa tlhahlobo e tšoanang le kotsi ea lefutso.

Lijo tsohle (meroho, litholoana, linate, lipeo, li-pulses, oli joalo-joalo) le litlatsetso tsa phepo li entsoe ka metsoako e fetang e le 'ngoe e sebetsang ea molek'hule kapa bio-active ka tekanyo le bongata bo fapaneng. Sejo se seng le se seng se sebetsang se na le mokhoa o ikhethileng oa ts'ebetso - e ka bang ts'ebetso kapa ho thibela litsela tse fapaneng tsa biochemical. Lijo le li-supplement tse khothalletsoang habonolo ke tse sa bakeng keketseho ea limolek'hule tsa mofetše empa li li fokotsa. Ho seng joalo, lijo tseo ha lia lokela ho khothaletsoa. Lijo li na le metsoako e mengata e sebetsang - ka hona, ha u hlahloba lijo le li-supplement, u lokela ho nahana ka phello ea metsoako eohle e sebetsang ka bonngoe ho e-na le hore u nahane ka bonngoe.

Ka mohlala Grapefruit e na le metsoako e sebetsang ea Chlorogenic Acid, Ferulic Acid, Curcumin, Isoliquiritigenin, Delphinidin. 'Me Pear e na le metsoako e sebetsang ea Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Genistein le mohlomong tse ling.

Phoso e tloaelehileng e entsoeng ha ho etsoa qeto le ho khetha lijo tse jeoang bakeng sa Waldenstrom Macroglobulinemia - ke ho hlahloba feela metsoako e sebetsang e khethiloeng e fumanehang lijong le ho hlokomoloha tse ling. Hobane metsoako e fapaneng e sebetsang e fumanehang lijong e kanna ea ba le litlamorao tse fapaneng ho bakhanni ba mofets'e - u ke ke ua khetha metsoako e sebetsang lijong le li-supplement bakeng sa ho etsa qeto ea phepo e nepahetseng bakeng sa Waldenstrom Macroglobulinemia.

EE – LIKHETHO TSA LIJO LI BOHLOKOA BAKENG SA KANKERE. LIQETO TSA PHEPO LI TLAMEHA HO NAHANA KA LITABA TSOHLE TSA LIJO.

Tsebo e Hlokahalang Bakeng sa Phepo ea Boipheliso bakeng sa Waldenstrom Macroglobulinemia?

Phepo ea motho ka mong bakeng sa mofetše joalo ka Waldenstrom Macroglobulinemia e na le lijo / li-supplement tse khothalelitsoeng; lijo tse sa khothaletsoang tse nang le mohlala oa diresepe tse etelletsang pele tšebeliso ea lijo tse khothaletsoang. Mohlala oa phepo e nepahetseng o ka bonoa ho sena link tsa.

Ho etsa qeto ea hore na ke lijo life tse khothalelitsoeng kapa che ho rarahane haholo, ho hloka boiphihlelo ho Waldenstrom Macroglobulinemia biology, mahlale a lijo, liphatsa tsa lefutso, biochemistry hammoho le kutloisiso e ntle ea hore na kalafo ea mofets'e e sebetsa joang le bofokoli bo amanang le bona boo kalafo e ka emisang ho sebetsa.

BONYENYANE BO TSEBO BOHLOKOA BAKENG SA PHEPO MOTHO BATHO BA KANKERE KE: BOLOJI YA KANKERE, SAENSE YA DIJO, DIPHEKO LA MOFEPO LE LIFUTSO.

Litšobotsi tsa mofets'e joalo ka Waldenstrom Macroglobulinemia

Lik'hemik'hale tsohle tse kang Waldenstrom Macroglobulinemia li ka khetholloa ka mekhoa e ikhethang ea lik'hemik'hale - litsela tsa ho saena tsa Waldenstrom Macroglobulinemia. Litsela tsa biochemical tse kang NFKB Signaling, Chromatin Remodeling, Growth Factor Signaling, MAPK Signaling ke karolo ea tlhaloso ea signature ea Waldenstrom Macroglobulinemia. Liphatsa tsa lefutso tsa mofetše oa motho e mong le e mong li ka fapana, ka hona, lets'oao la bona la mofets'e le ka ikhetha.

Liphekolo tse sebetsang hantle bakeng sa Waldenstrom Macroglobulinemia li hloka ho ela hloko mekhoa ea lik'hemik'hale e amanang le eona bakeng sa mokuli e mong le e mong oa mofetše le motho ea kotsing ea lefutso. Ka hona liphekolo tse fapaneng tse nang le mekhoa e fapaneng ea liketso li sebetsa hantle ho bakuli ba fapaneng. Ka mokhoa o ts'oanang le ka mabaka a ts'oanang lijo le li-supplement li hloka ho etsoa ka bomong bakeng sa motho ka mong. Kahoo lijo tse ling le li-supplement li khothaletsoa bakeng sa Waldenstrom Macroglobulinemia ha u nka kalafo ea mofetše Ibrutinib, 'me lijo tse ling le li-supplement ha li khothalletsoe.

Mehloli e kang cBioPortal 'me ba bang ba bangata ba fana ka lintlha tse sa tsejoeng tse tsoang litekong tsa bongaka bakeng sa matšoao ohle a mofetše. Lintlha tsena li na le lintlha tsa boithuto ba tleliniki joalo ka boholo ba sampole / palo ea bakuli, lihlopha tsa lilemo, bong, morabe, kalafo, sebaka sa tumor le liphetoho life kapa life tsa lefutso.

ARID1A, IGF1R, MAP3K1 le MYD88 ke mefuta e holimo e tlalehiloeng ea Waldenstrom Macroglobulinemia. ARID1A e tlalehoa ho 100.0% ea bakuli ba baemeli ho pholletsa le liteko tsohle tsa bongaka. 'Me IGF1R e tlalehoa ka 100.0%. Lintlha tse kopaneng tsa bakuli li akaretsa lilemo ho tloha ho. 100.0% ea data ea bakuli e tsejoa e le banna. The Waldenstrom Macroglobulinemia biology hammoho le liphatsa tsa lefutso tse tlalehiloeng hammoho li hlalosa palo ea batho ba emetseng mekhoa ea lik'hemik'hale ea mofetše bakeng sa mofetše ona. Haeba liphatsa tsa lefutso tsa mofetše kapa liphatsa tsa lefutso tse kenyang kotsi le tsona li tsejoa, seo se lokela ho sebelisoa hape bakeng sa ho ja lijo.

LIKHETHO TSA PHEPO LI LOKELA HO TŠOANA LE MOTHO E MONG LE E MONG LE SAENYO EA MOTHO EA KANKERE.

Lijo le Tlatsetso bakeng sa Waldenstrom Macroglobulinemia

Bakeng sa Bakuli ba Kankere

Bakuli ba mofetše ba nakong ea kalafo kapa ba tlhokomelong ea pholiso ba lokela ho etsa liqeto mabapi le lijo le li-supplement - bakeng sa lik'hilojule tse hlokahalang tsa lijo, ho laola litla-morao life kapa life tsa kalafo le bakeng sa taolo e ntlafetseng ea mofetše. Lijo tsohle tse thehiloeng ho limela ha li lekane, 'me ho khetha le ho etelletsa pele lijo tse ikhethileng le tse etselitsoeng kalafo e tsoelang pele ea mofets'e ho bohlokoa ebile ho rarahane. Mehlala ke ena e fanang ka litataiso bakeng sa ho etsa liqeto tsa phepo e nepahetseng.

Khetha makhasi a CHICORY a meroho kapa SQUASH ea Mariha?

Makhasi a Chicory ea meroho a na le metsoako e mengata e sebetsang kapa bioactives tse kang Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Apigenin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Makhasi a Chicory a khothaletsoa bakeng sa Waldenstrom Macroglobulinemia ha kalafo ea mofetše e tsoelang pele e le Ibrutinib. Lebaka ke hobane Makhasi a Chicory a fetola litsela tseo tsa biochemical tse tlalehiloeng ka mahlale ho hlokomelisa phello ea Ibrutinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa meroho ea Winter Squash ke Chlorogenic Acid, Protocatechuic Acid, Isoliquiritigenin, Apigenin, Curcumin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Winter Squash ha e khothalletsoe bakeng sa Waldenstrom Macroglobulinemia ha phekolo ea mofetše e tsoelang pele e le Ibrutinib hobane e fetola litsela tsa biochemical tse etsang hore phekolo ea mofetše e se ke ea sebetsa kapa e se ke ea arabela.

MAKHASI A MOROO A CHICORY A KHOTHATSOA KA NAKO EA SQUASH YA MARIHA BAKENG SA Waldenstrom Macroglobulinemia LE PHEKO Ibrutinib.

Khetha Fruit PEAR kapa GRAPEFRUIT?

Fruit Pear e na le metsoako e mengata e sebetsang kapa bioactives tse kang Chlorogenic Acid, Gallic Acid, Isoliquiritigenin, Curcumin, Genistein. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Pear e buelloa bakeng sa Waldenstrom Macroglobulinemia ha phekolo ea kankere e tsoelang pele e le Ibrutinib. Sena ke hobane Pear e fetola litsela tseo tsa biochemical tse tlalehiloeng ka mahlale ho hlokomelisa phello ea Ibrutinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana tsa morara ke Chlorogenic Acid, Ferulic Acid, Curcumin, Isoliquiritigenin, Delphinidin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Grapefruit ha e khothalletsoe bakeng sa Waldenstrom Macroglobulinemia ha kalafo ea mofetše e tsoelang pele e le Ibrutinib hobane e fetola litsela tsa biochemical tse etsang hore kalafo ea mofets'e e se ke ea sebetsa kapa e se ke ea arabela hantle.

PEAR YA THOLOANA E TLHOKOMELISOA HO FETISISA GRAPEFRUIT BAKENG SA Waldenstrom Macroglobulinemia LE PHEKO Ibrutinib.

Khetha Nut WALNUT kapa WALNUT ea JAPANESE?

Walnut e na le metsoako e mengata e sebetsang kapa bioactives tse kang Carvacrol, Chlorogenic Acid, Protocatechuic Acid, Curcumin, Isoliquiritigenin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Walnut e buelloa bakeng sa Waldenstrom Macroglobulinemia ha phekolo ea kankere e tsoelang pele e le Ibrutinib. Sena ke hobane Walnut e fetola litsela tsa biochemical tse tlalehiloeng ka mahlale hore li hlokomelisa phello ea Ibrutinib.

Tse ling tsa metsoako e sebetsang kapa li-bioactive ka Walnut ea Japane ke Chlorogenic Acid, Protocatechuic Acid, Apigenin, Curcumin, Isoliquiritigenin. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka NFKB Signaling le tse ling. Japanese Walnut ha e khothalletsoe bakeng sa Waldenstrom Macroglobulinemia ha phekolo ea mofetše e tsoelang pele e le Ibrutinib hobane e fetola litsela tseo tsa lik'hemik'hale tse etsang hore phekolo ea mofetše e se ke ea sebetsa kapa e se ke ea arabela.

WALNUT E KHOTHATSOE HO FETISISA WALNUT YA JAPANESE BAKENG SA Waldenstrom Macroglobulinemia LE PHEKO Ibrutinib.

Bakeng sa Batho ba nang le Kotsi ea Liphatsa tsa Kankere

Potso e botsoang ke batho ba nang le kotsi ea lefutso ea Waldenstrom Macroglobulinemia kapa nalane ea lelapa ke "Ke Lokela ho Ja Eng e Fapaneng le Pele?" le kamoo ba lokelang ho khetha lijo le li-supplement bakeng sa ho laola likotsi tsa lefu lena. Kaha bakeng sa kotsi ea mofets'e ha ho letho le ka etsoang mabapi le kalafo - liqeto tsa lijo le li-supplement li fetoha tsa bohlokoa 'me e le e' ngoe ea lintho tse fokolang haholo tse ka etsoang. Lijo tsohle tse thehiloeng ho limela ha li lekane 'me li ipapisitse le liphatsa tsa lefutso le mokhoa oa ho saena - khetho ea lijo le li-supplement li lokela ho etsoa ke motho ka mong.

Khetha Vegetable GIANT BUTTERBUR kapa Mustard SPINACH?

Vegetable Giant Butterbur e na le metsoako e mengata e sebetsang kapa bioactives tse kang Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Cell Cycle, P53 Signaling, MAPK Signaling le MYC Signaling le tse ling. Giant Butterbur e buelloa bakeng sa kotsi ea Waldenstrom Macroglobulinemia ha kotsi ea lefutso e amanang le ARID1A. Sena ke hobane Giant Butterbur e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba eona.

Tse ling tsa metsoako e sebetsang kapa li-bioactives tsa Mustard Spinach ea meroho ke Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Epithelial ho Mesenchymal Transition, WNT Beta Catenin Signaling le NFKB Signaling le tse ling. Mustard Spinach ha e khothalletsoe ha kotsi ea Waldenstrom Macroglobulinemia e amahanngoa le kotsi ea lefutso e le ARID1A hobane e eketsa litsela tsa eona.

BUTERBURU E KHOLO EA MERO E KHOTHATSOE HO FETA SPINACH EA Mustard BAKENG SA ARID1A KOTSI EA LIFUNYO EA MOTSOALLE.

Khetha Litholoana JAVA PLUM kapa PUMMELO?

Litholoana tsa Java Plum li na le metsoako e mengata e sebetsang kapa li-bioactive tse kang Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Cell Cycle, P53 Signaling, MAPK Signaling le MYC Signaling le tse ling. Java Plum e buelloa bakeng sa kotsi ea Waldenstrom Macroglobulinemia ha kotsi ea lefutso e amanang le ARID1A. Sena ke hobane Java Plum e eketsa litsela tsa biochemical tse hanyetsanang le bakhanni ba saena ba eona.

Tse ling tsa metsoako e sebetsang kapa li-bioactive tsa litholoana Pummelo ke Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical joalo ka Epithelial ho Mesenchymal Transition le WNT Beta Catenin Signaling le tse ling. Pummelo ha e khothalletsoe ha kotsi ea Waldenstrom Macroglobulinemia e amahanngoa le kotsi ea liphatsa tsa lefutso ke ARID1A hobane e eketsa litsela tsa ho saena.

FRUIT JAVA PLUM E KHOTHATSOE HO FETISISA PUMMELO BAKENG SA ARID1A Genese RISK EA KANKERE.

Khetha Nut BUTTERNUT kapa FLEXSEED?

Butternut e na le metsoako e mengata e sebetsang kapa li-bioactive tse kang Curcumin, Apigenin, Lupeol, Daidzein, Lycopene. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang Cell Cycle, P53 Signaling, MAPK Signaling le MYC Signaling le tse ling. Butternut e khothaletsoa bakeng sa kotsi ea Waldenstrom Macroglobulinemia ha kotsi ea lefutso e amanang le ARID1A. Lebaka ke hobane Butternut e eketsa litsela tsa biochemical tse khahlano le bakhanni ba eona ba saenneng.

Tse ling tsa metsoako e sebetsang kapa bioactives ho Flaxseed ke Curcumin, Apigenin, Lupeol, Daidzein, Beta-sitosterol. Lisebelisoa tsena tse sebetsang li laola litsela tse fapaneng tsa biochemical tse kang MAPK Signaling, Epithelial to Mesenchymal Transition, WNT Beta Catenin Signaling le PI3K-AKT-MTOR Signaling le tse ling. Flaxseed ha e khothalletsoe ha kotsi ea Waldenstrom Macroglobulinemia e amahanngoa le kotsi ea liphatsa tsa lefutso ke ARID1A hobane e eketsa litsela tsa eona.

BUTTERNUT E KHOTHATSOA HO FETISISA FLAXSEED BAKENG SA ARID1A genetic RISK EA KANKERE.

Ha re phethela

Lijo le Tlatsetso tse khethiloeng ke liqeto tsa bohlokoa bakeng sa mofetše joalo ka Waldenstrom Macroglobulinemia. Bakuli ba Waldenstrom Macroglobulinemia le batho ba nang le kotsi ea lefutso ba lula ba e-na le potso ena: "Ke lijo life le li-supplement tsa phepo tse khothalletsoang ho 'na le tse sa buelloang?" Ho na le tumelo e tloaelehileng eo e leng maikutlo a fosahetseng a hore lijo tsohle tse thehiloeng limela li ka ba molemo kapa che empa li ke ke tsa e-ba kotsi. Lijo tse ling le li-supplement li ka kena-kenana le phekolo ea mofetše kapa tsa khothalletsa bakhanni ba limolek'hule tsa mofetše.

Ho na le mefuta e fapaneng ea matšoao a mofets'e joalo ka Waldenstrom Macroglobulinemia, e 'ngoe le e' ngoe e na le liphatsa tsa lefutso tse fapaneng tse nang le mefuta e meng ea genomic ho motho ka mong. Ho feta moo kalafo e 'ngoe le e' ngoe ea mofetše le chemotherapy e na le mokhoa o ikhethileng oa ts'ebetso. Sejo se seng le se seng joalo ka Makhasi a Chicory se na le li-bioactive tse fapaneng ka bongata bo fapaneng, tse nang le tšusumetso litseleng tse fapaneng le tse ikhethileng tsa lik'hemik'hale tsa biochemical. Tlhaloso ea phepo e nepahetseng ke likhothaletso tsa motho ka mong bakeng sa sesupo sa mofetše, kalafo, liphatsa tsa lefutso, mokhoa oa bophelo le lintlha tse ling. Liqeto tsa phepo e nepahetseng bakeng sa mofetše li hloka tsebo ea biology ea mofets'e, mahlale a lijo le kutloisiso ea liphekolo tse fapaneng tsa chemotherapy. Qetellong ha ho e-na le liphetoho tsa phekolo kapa li-genomics tse ncha li khetholloa - phepo e nepahetseng e hloka ho hlahlojoa bocha.

Tharollo ea motho ka mong ea phepo e nepahetseng ea addon e etsa hore ho etsa liqeto ho be bonolo 'me e tlose menahano eohle ho araba potso e reng, "Ke lijo life tseo ke lokelang ho li khetha kapa ho se khethe bakeng sa Waldenstrom Macroglobulinemia?". Sehlopha sa li-addon tse nang le taeo e mengata se kenyelletsa lingaka tsa mofetše, bo-ramahlale ba bongaka, baenjiniere ba mananeo le bo-ramahlale ba data.

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