Kansarkee ayaa ka faa'iidaysan doona in lagu daro Buckwheat cuntadooda?

Tilmaamaha

Buckwheat ayaa si weyn loogu aqoonsan yahay faa'iidooyinkeeda caafimaad waxaana si joogto ah u isticmaala bukaannada kansarka iyo kuwa halista ugu jira hiddaha. Hase yeeshee, badbaadada iyo waxtarka Buckwheat ee bukaannada kansarka waxay ku xiran tahay arrimo badan sida calaamadda kansarka, daaweynta kemotherabi, daawaynta kale, iyo hiddaha burada. Ogaanshaha in qaar ka mid ah cuntooyinka iyo kaabisyada, sida canabka iyo isbinaajka, laga yaabo in ay si liidata ula falgalaan daawooyinka kansarka oo ay keenaan fal-celin xun waa muhiim.

Cuntadu waxay muhiim u tahay daaweynta kansarka sababtoo ah waxay saameyn kartaa natiijooyinka daaweynta. Bukaannada kansarku waa inay si taxadar leh u doortaan oo ku daraan cuntooyinka ku habboon iyo kaabista cuntadooda. Tusaale ahaan, Buckwheat waxa ay ka faa'iidaysan kartaa kuwa qaba Burada Asaasiga ah ee Neuroendocrine ee ku socota Shucaaca, laakiin waxaa laga yaabaa inaanay u fiicnayn bukaanada qaata Azacitidine ee Primary Juvenile Myelomonocytic Leukemia. Intaa waxaa dheer, halka Buckwheat ay caawin karto shakhsiyaadka leh khatarta hidde-sidaha "CDKN2A", waxaa laga yaabaa in aan loo soo jeedin kuwa leh khatarta hidde ee kala duwan "ATM". Shakhsiyeynta qorshayaasha cuntada ee ku salaysan caafimaadka, daawaynta, iyo hidaha waa lama huraan.

Fahamka in go'aan ka gaarista ku habboonaanta Buckwheat ee bukaanka kansarka uu u baahan yahay in shakhsi ahaan loo sameeyo waa muhiim. Qodobbada muhiimka ah sida nooca kansarka, hababka daawaynta, qurxinta hidda-socodka, khatarta hidda-socodka, da'da, miisaanka jidhka, iyo qaab nololeedka ayaa muhiim u ah go'aaminta haddii Buckwheat uu yahay doorashada habboon. Genetics iyo genomics, gaar ahaan, waa tixgelin muhiim ah. Maadaama arrimahan ay kobci karaan, waxaa lama huraan ah in si joogto ah dib loogu eego oo la waafajiyo doorashooyinka cuntada si loo waafajiyo isbeddelada xaaladda caafimaadka iyo daaweynta.

Gebagebadii, habka dhammaystiran ee doorashooyinka cuntada ayaa muhiim ah, iyadoo diiradda la saarayo saamaynta guud ee dhammaan qaybaha firfircoon ee cuntooyinka/kaabka sida Buckwheat halkii laga qiimayn lahaa shay kasta oo firfircoon si gooni ah ama gebi ahaanba la iska indho-tiray. Aragtida ballaadhan waxay kobcinaysaa hab macquul ah oo cilmiyaysan oo loogu talagalay qorsheynta cuntada ee kansarka.

Dulmar Kooban

Isticmaalka cuntooyinka dhirta ku salaysan iyo waxyaalaha dheeriga ah, sida fiitamiinada, geedo yaryar, macdanta, probiotics, iyo supplements-ka gaarka ah ee kala duwan, ayaa ku soo badanaya bukaannada kansarka. Kaabayaashan waxaa loogu talagalay in lagu bixiyo uruurin sare oo ah maaddooyin firfircoon oo gaar ah, kuwaas oo qaar badan oo ka mid ah ay sidoo kale ku jiraan cuntooyin kala duwan. U fiirsashada iyo kala duwanaanta maaddooyinka firfircooni waxay ku kala duwan yihiin cuntooyinka oo dhan iyo kaabista. Cuntooyinka sida caadiga ah waxay bixiyaan noocyo kala duwan oo maaddooyin firfircoon ah laakiin xaddi hoose, halka kaabayaashu ay bixiyaan uruurin sare oo ah maaddooyin gaar ah.

Iyadoo la tixgalinayo shaqooyinka kala duwan ee sayniska iyo bayooloji ee walax kasta oo firfircoon heerka molecular, waxaa muhiim ah in lagu xisaabtamo saamaynta isku dhafan ee qaybahan marka la go'aaminayo cuntooyinka iyo kaabayaasha in la cuno iyo in kale.

Su'aasha muhiimka ah ayaa soo baxaysa: Miyaad ku dari kartaa Buckwheat cuntadaada sida shay cunto ama kabitaan ah? Ma lagugula talinayaa inaad isticmaasho Buckwheat haddii aad leedahay cudurka kansarka ee la xidhiidha hidde-sidayaasha CDKN2A? Maxaa dhacaya haddii taa beddelkeeda khatartaada hidde-sidaha ay ka timid hidda-wadaha ATM-ka? Faa'iido ma u leedahay in lagu daro buckwheat cuntadaada haddii lagaa helo cudurka 'Leukemia Primary Juvenile Myelomonocytic Leukemia', ama haddii cilad-sheegashadaadu tahay Tumorka Neuroendocrine Primary Esophageal? Waxaa intaa dheer, sidee loo hagaajin karaa isticmaalka Buckwheat haddii aad marayso daawaynta shucaaca ama haddii qorshahaaga daawaynta uu ka wareego Shucaaca una wareego Azacitidine? Waa lagama maarmaan in la aqoonsado in sheegashada fudud sida 'Buckwheat ay tahay mid dabiici ah, markaa had iyo jeer waa faa'iido' ama 'Buckwheat waxay kordhisaa difaaca' kuma filna doorashada cuntada/kabka.

Intaa waxaa dheer, waa lagama maarmaan in dib loo qiimeeyo ku habboonaanta in lagu daro Buckwheat cuntadaada haddii ay jiraan isbeddelo ku yimaada habka daaweyntaada. Marka la soo koobo, marka aad go'aan ka gaareyso ku darida cuntooyinka ama kaabista sida Buckwheat ee cuntadaada faa'iidooyinkeeda, waa inaad tixgelisaa saameynta guud ee biochemical ee dhammaan maaddooyinka, adigoo tixgelinaya arrimo ay ka mid yihiin nooca kansarka, daawaynta gaarka ah ee aad marayso, saadaalin hidde , iyo doorashada qaab nololeedka.

Kansarka

Kansarka ayaa weli ah caqabad weyn oo dhanka caafimaadka ah, isagoo inta badan keena walaac baahsan. Si kastaba ha ahaatee, horumarradii ugu dambeeyay ayaa hagaajiyay natiijooyinka daaweynta, gaar ahaan iyada oo loo marayo hababka daawaynta shakhsi ahaaneed, hababka kormeerka aan fiicneyn ee dhiigga iyo shaybaarada candhuufta, iyo horumarinta immunotherapy. Ogaanshaha hore iyo ka-hortagga wakhtiga ayaa ahaa mid muhiim u ah si wax ku ool ah u saameeya natiijooyinka guud ee daaweynta.

Tijaabada hidde-sidaha waxay bixisaa ballan-qaad muhiim ah oo lagu qiimeeyo khatarta kansarka iyo u nuglaanta goor hore. Si kastaba ha ahaatee, shakhsiyaad badan oo qaba qoyska iyo hidde-sidaha kansarka, fursadaha faragelinta daweynta, xitaa la socodka joogtada ah, badanaa waa xaddidan yihiin ama midna. Marka lagu ogaado nooc gaar ah oo kansar ah, sida Tumor Esophageal Neuroendocrine Primary ama Primary Juvenile Myelomonocytic Leukemia, xeeladaha daawaynta waxay u baahan yihiin in la habeeyo iyadoo lagu saleynayo hidda-wadaha qofka, heerka cudurka, iyo sidoo kale arrimaha sida da'da iyo jinsiga. "

Daawaynta ka dib, la socodka joogtada ahi waa lama huraan si loo ogaado calaamad kasta oo ah soo noqoshada kansarka iyo in lagu wargeliyo go'aamada xiga. Bukaanno badan oo kansar ah iyo kuwa halista ku jira ayaa inta badan raadsada talo ku saabsan ku daridda cuntooyinka qaarkood iyo kaabisyada cuntadooda, taas oo door muhiim ah ka ciyaarta guud ahaan habka go'aan qaadashada ee ku saabsan maaraynta caafimaadka.

Su'aasha muhiimka ah ayaa ah in la tixgeliyo khatarta hidda-socodka iyo ogaanshaha kansarka gaarka ah marka la go'aaminayo doorashooyinka cuntada, sida Buckwheat. Khatarta hidde-sidaha kansarka ee ka timaadda isbeddelka CDKN2A ma leedahay saameyn la mid ah dariiqa biochemical ee isbeddelka ATM-ka? Marka laga eego dhinaca nafaqeynta, khatarta la xiriirta Tumor Esophageal Neuroendocrine ee Aasaasiga ah miyay la mid tahay Curyaaminta Myelomonocytic Leukemia ee Hore? Intaa waxaa dheer, tixgalinta cuntadu miyay isku mid ahaanaysaa kuwa qaadanaya Azacitidine iyo kuwa qaata shucaaca? Tixgelintan ayaa muhiim u ah samaynta doorashooyin cunto oo xog-ogaal ah oo loogu talagalay shakhsiyaadka leh khataraha hidde-sidaha ee kala duwan iyo daaweynta kansarka.

Buckwheat - Kaab Nafaqo ah

Buckwheat-ka dheeriga ah wuxuu ka kooban yahay noocyo kala duwan oo maaddooyin firfircoon ah, oo ay ku jiraan Rutin, Oleic Acid, Linoleic Acid, Citric Acid iyo Beta-sitosterol, mid kasta oo jooga oo leh heerar kala duwan. Maaddooyinkaani waxay saameeyaan dariiqyada molecular, gaar ahaan MYC Signaling, PI3K-AKT-MTOR Signaling, RAS-RAF Signaling iyo Notch Signaling, kuwaas oo nidaamiya dhinacyada muhiimka ah ee kansarka heerka gacanta, sida koritaanka burada, faafidda, iyo dhimashada unugga. Marka la eego saameyntan bayoolojiga ah, xulashada kaabayaasha ku habboon sida Buckwheat, kaligiis ama isku darka, waxay noqotaa go'aan muhiim ah marka la eego macnaha nafaqeynta kansarka. Markaad ka fekereyso isticmaalka Buckwheat kansarka, waxaa lagama maarmaan ah in la tixgeliyo arrimahan iyo hababka kala duwan. Tani waa sababta oo ah, si la mid ah daaweynta kansarka, isticmaalka Buckwheat ma aha go'aan caalami ah oo ku habboon dhammaan kansarrada laakiin waxay u baahan tahay in la shakhsiyeeyo.

Doorashada Kaabayaasha Buckwheat

Wax ka qabashada su'aasha 'Goorma ayaan ka fogaanayaa Buckwheat macnaha guud ee Kansarka' waa caqabad sababtoo ah jawaabtu waa mid gaar ah - waxay si fudud u tahay 'Waxay ku xiran tahay!'. Si la mid ah sida daawaynta kansarku aanay waxtar ugu yeelan bukaan kasta, ku habboonaanta iyo badbaadada ama faa'iidooyinka Buckwheat way kala duwan yihiin iyadoo ku xidhan duruufaha shakhsi ahaaneed. Waxyaabaha ay ka midka yihiin nooca gaarka ah ee kansarka, saadaalinta hidde-sideyaasha, daawaynta hadda, kaabisyada kale ee la qaato, hab-nololeedka, BMI, iyo xasaasiyad kasta oo dhan waxay door ka ciyaaraan go'aaminta in Buckwheat ku habboon tahay ama ay tahay in laga fogaado, iyada oo hoosta ka xariiqaysa muhiimada tixgelinta shakhsi ahaaneed go'aamadan oo kale.

1. Kaabista Buckwheat ma ka faa'iidaysan doontaa Primary Juvenile Myelomonocytic Leukemia Bukaan-socodka lagu daweynayo Azacitidine?

Primary Juvenile Myelomonocytic Leukemia waxaa lagu gartaa isbeddellada hidde-sidaha gaarka ah, kuwaas oo kala ah PTPN11, NRAS iyo NF1, kuwaas oo horseedaya isbeddel ku yimaadda dariiqyada biochemical, gaar ahaan Angiogenesis, C-nooca Lectin Reseptor Signaling, G-protein-ku-xidhan yahay Soo-dhoweeyaha, Calaamadaynta Sababta Kobaca, MAPK iyo PI3K-AKT-MTOR Signaling. Waxtarka daaweynta kansarka, sida Azacitidine, waxay ku xiran tahay habka ay u shaqeyso ee waddooyinkan gaarka ah. Istaraatiijiyadda ugu habboon waxay ku lug leedahay in la waafajiyo ficilka daawaynta iyo waddooyinka kansarka, si loo hubiyo hab shakhsiyeed oo waxtar leh. Xaaladahan oo kale, ka fogaanshaha cuntooyinka ama dheellitirka nafaqeynta ee laga yaabo inay ka hortagaan saameynta daaweynta ama hoos u dhigta isku-habayntan ayaa muhiim ah. Tusaale ahaan, kabka Buckwheat, kaas oo saameeya PI3K-AKT-MTOR Signaling, waxaa laga yaabaa inaysan ahayn doorashada saxda ah ee kiiska Primary Juvenile Myelomonocytic Leukemia marka la qaadanayo Azacitidine. Tani waa sababta oo ah waxay ka sii dari kartaa horumarka cudurka ama waxay faragelin kartaa waxtarka daaweynta. Markaad dooranayso qorshaha nafaqeynta, waxaa muhiim ah in la tixgeliyo arrimo ay ka mid yihiin nooca kansarka, daawaynta socota, da'da, jinsiga, BMI, qaab nololeedka, iyo isbeddellada hidde-sidaha ee la yaqaan.

2. Kaabitaanka Buckwheat ma ka faa'iidaysan doonaan Bukaannada Bukaanka ah ee Neuroendocrine ee Esophageal ee u socda daawaynta shucaaca?

Unugyada asaasiga ah ee Neuroendocrine Tumor waxaa lagu gartaa isbeddellada hidda-socodka ee gaarka ah, sida TP53, RB1 iyo APEX1, taas oo keenta isbeddel ku yimaada dariiqyada biochemical, gaar ahaan MYC Signaling, Isbaarada wareegga unugyada, Apoptosis iyo Dayactirka DNA. Waxtarka daaweynta kansarka, sida Shucaaca, waxaa lagu go'aamiyaa la falgalka waddooyinkan. Ujeeddadu waa in la hubiyo in daawadu ay si fiican ula jaanqaado dariiqooyinka keena kansarka, taasoo awood u siinaysa hab daawaynta shakhsi ahaaneed. Xaaladdan oo kale, cuntooyinka ama kaabeyaasha ku habboon daawaynta ama kor u qaadaysa isku-habayntan waa in la tixgeliyo. Tusaale ahaan, kabka Buckwheat waa ikhtiyaar maangal ah oo loogu talagalay kuwa qaba Burada Neuroendocrine ee hore ee hunguriga ee shucaaca. Tani waa sababta oo ah Buckwheat wuxuu saameeyaa dariiqyada sida MYC Signaling, kaas oo xannibi kara waxyaabaha keenaya Burada Neuroendocrine Primary Esophageal ama faa'iido u leedahay waxtarka Shucaaca.

3. Kaabayaasha Buckwheat ma yihiin kuwo badbaado u ah Shakhsiyaadka Caafimaadka qaba ee leh Isku-beddelka ATM-ka ee ku xidhan Khatarta Hiddaha?

Shirkado kala duwan ayaa bixiya unugyada hidde-sidaha si ay u qiimeeyaan halista hidde-sidaha ee noocyada kala duwan ee kansarrada. Qaybahaan waxaa ka mid ah hidde-sideyaasha ku xiran naaska, ugxan-sidaha, uterineine-ka, qanjirka 'prostate', iyo kansarka mindhicirka. Tijaabinta hidde-sideyaashan waxay xaqiijin kartaa ogaanshaha cudurka waxayna ku wargelin kartaa daaweynta iyo xeeladaha maaraynta. Aqoonsiga kala duwanaanshaha sababa cudurku waxa uu sii caawin karaa baadhista iyo ogaanshaha qaraabada khatarta ku jira. Hidde-sidayaasha ATM-ka ayaa inta badan lagu daraa qaybahan si loo qiimeeyo khatarta kansarka.

Isbeddelka hiddasidaha ATM-ka wuxuu saameeyaa dariiqyada ama hababka biochemical, sida RAS-RAF Signaling iyo Dayactirka DNA, kuwaas oo si toos ah ama si dadban ugu lug leh wadista kansarka heerka molecular. Marka guddiga hidde-sidaha ay aqoonsadaan isbeddelka ATM-ka ee la xidhiidha khatarta sii kordheysa ee Myelomonocytic Leukemia, fikradda sayniska ayaa soo jeedinaysa in laga fogaado isticmaalka kabka Buckwheat. Tani waa sababta oo ah kaabashka Buckwheat wuxuu saameeyaa dariiqyada sida RAS-RAF Signaling, taas oo u horseedi karta saameyn xun marka la eego isbeddelka ATM-ka iyo xaaladaha kansarka ee la xiriira.

4. Kaabayaasha Buckwheat ma yihiin kuwo badbaado u ah Shakhsiyaadka Caafimaadka qaba ee qaba CDKN2A Mutation Associated Khatarta Hiddaha?

CDKN2A waxay door muhiim ah ka ciyaartaa qiimaynta halista kansarka. Isbeddellada ku jira CDKN2A waxay carqaladayn karaan dariiqyada biochemical ee muhiimka ah, oo ay ku jiraan Calaamadaynta Notch, Isbaarada Wareegga Unugyada iyo Wareegga Unugyada, kuwaas oo saameeya horumarka kansarka. Haddii guddigaaga hidde-sidaha uu muujiyo isbeddellada CDKN2A ee la xidhiidha Kansarka Maqaarka, ka fiirso in lagu daro kaabisyada Buckwheat qorshahaaga nafaqeynta. Kaabayaashan waxay si togan u saameyn karaan dariiqyada sida Signaling Notch, waxay ka faa'iideysan karaan iyagoo siinaya taageero ku habboon shakhsiyaadka leh isbeddellada CDKN2A iyo welwelka caafimaadka ee la xiriira.

In Gabagabo

Labada shay ee ugu muhiimsan in la xasuusto waa in daawaynta kansarka iyo nafaqeynta aysan weligood isku mid ahayn qof walba. Nafaqada, oo ay ku jiraan cuntada iyo kaabista sida Buckwheat, waa qalab wax ku ool ah oo lagu xakameyn karo adiga markaad wajaheyso kansarka.

"Maxaan cunaa?" waa su'aasha ugu badan ee ay weydiiyaan bukaannada kansarka iyo kuwa halista ugu jira kansarka. Jawaabta saxda ah waa in ay ku xiran tahay arrimo ay ka mid yihiin nooca kansarka, hidde-sideyaasha burada, daawaynta hadda, xasaasiyadda, qaab nololeedka, iyo BMI.

Ka hel shakhsiyayntaada nafaqada ee kansarka addon adiga oo gujinaya xidhiidhka hoose oo ka jawaabaya su'aalaha ku saabsan nooca kansarka, daawaynta, qaab nololeedkaaga, xasaasiyadahaaga, da'da, iyo jinsigaaga.

tixraacyada

• [Ahmiyadda caafimaad ee cilladaha dheef-shiid kiimikaadka zinc].
• Paederia foetida waxay kicisaa dhaqdhaqaaqa ka hortagga kansarka iyadoo wax ka beddelaysa enzymes-ka beddelka chromatin iyo beddelidda muujinta hidda-wadaha cytokine-ka-bararka ee unugyada kansarka qanjirka 'prostate'.
• cBioPortal ee Kansarka Genomics
• Saamaynta K-RAS oncogenic ee fosforyaalka YB-1 oo ay keentay shucaaca ionizing.
• β-Sitosterol iyo Gemcitabine waxay soo bandhigaan Dhaqdhaqaaqa Kansarka Ka-hortagga Pancreatic Synergistic iyadoo la beddelayo Apoptosis iyo Joojinta Kala-guurka Epithelial-Mesenchymal iyadoo la joojinayo Akt/GSK-3β Calaamadeynta.