Cuntooyinka loogu talagalay Burooyinka Phyllodes!

Hordhac

Cuntooyinka loogu talagalay Burooyinka Phyllodes waa in loo gaaryeelaa shaqsi kasta waana in ay la qabsadaan marka daaweynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Burooyinka Phyllodes waa burooyinka naasaha ee fibroepithelial naadir ah oo xisaabiya in ka yar 0.5% dhammaan kansarrada naasaha. Burooyinkani waxay noqon karaan kuwo aan fiicneyn, xuduud ama malignant waxayna leeyihiin heerar sare oo soo noqnoqoshada maxaliga ah, halka qaabka xuni uu soo saari karo, inta badan sambabada. Boderline iyo phyllodes malignant heerka metastasis ee burada waa qiyaastii 25-31%, halka heerka guud ee phyllodes metastasis-ka burada uu yahay 4%. Nabarrada burooyinka phyllodes naasku inta badan waa hal, nodular, tiro aan xanuun lahayn oo leh bilow hoose iyo horumar gaabis ah. Badi bukaanada qaba burooyinka phyllodes ee aan fiicneyn iyo kuwa xuduudka leh ayaa lagu daaweeyaa qaliin. Daaweynta adjuvant ee qalliinka kadib waxaa ku jiri kara daaweynta shucaaca ama kiimoterabiga si looga hortago soo noqoshada burooyinka phyllodes ee xun. Qiyaasta badbaadada 5-sano ee burooyinka phyllodes-ka xun waa qiyaastii 60-80%. Nafaqada ugu fiican (cuntooyinka iyo kaabayaasha dabiiciga ah) ee ku habboon nooca burada iyo xaaladda daawaynta waxay sii caawin kartaa hagaajinta badbaadada iyo tayada nolosha. (Tixraac: Zhou Z-R et al, J ee Cudurka Thoracic, 2016; Demain GA et al, J ee Masaarida Natl 'Cancer Inst., 2016)

Burooyinka Phyllodes miyay muhiim u tahay khudaarta, miraha, lawska, miraha la cuno?

Su'aal nafaqeed oo aad u caan ah oo ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka khatarta hidde-sidaha ee kansarka ayaa ah - kansarka sida Phyllodes Tumors miyay muhiim tahay cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Burooyinka Phyllodes?

Tusaale ahaan miyay muhiim tahay haddii khudaarta Saytuun la isticmaalo in ka badan marka la barbar dhigo bocorka Japan? Miyay wax farqi ah samaynaysaa haddii khudaarta Pummelo laga doorbido khudaar? Sidoo kale haddii xulashooyin la mid ah loo sameeyo lowska/abuurka sida Cashew Nut oo ka sarreeya Colorado Pinyon iyo garaacyada sida Yellow Wax Bean oo ka sarreeya digirta caadiga ah. Oo haddii waxa aan cuno ay arrintu khusayso - markaa sidee loo aqoonsan karaa cuntooyinka lagu taliyay Burooyinka Phyllodes oo ma isku mid bay u tahay qof kasta oo leh isla cudurka ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Burooyinka Phyllodes!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pummelo waxa ku jira maaddooyinka firfircoon ee Quercetin, Caffeine, Curcumin, Genistein, Apigenin. Khudradu waxay ka kooban tahay maaddooyinka firfircoon ee Quercetin, Curcumin, Beta-carotene iyo kuwa kale oo suurtogal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno ee Burooyinka Phyllodes - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Burooyinka Phyllodes.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Looga Baahan Yahay Nafaqaynta Shakhsiyaynta Burooyinka Phyllodes?

Nafaqada shakhsi ahaaneed ee kansarka sida Phyllodes Tumors waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo kuwa aan lagu talin waa mid aad u dhib badan, waxay u baahan tahay khibrada Phyllodes Tumors bayoloji, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha kuwaas oo daaweyntu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Burooyinka Phyllodes

Dhammaan kansarrada sida Phyllodes Tumors waxaa lagu sifeyn karaa waddooyin gaar ah oo biochemical ah - dariiqooyinka saxiixa ee Burooyinka Phyllodes. Dariiqooyinka biochemical sida Dayactirka DNA, Calaamadaynta TGFB, Oncogenic Histone Methylation, Dib-u-habaynta Matrix Extracellular waa qayb ka mid ah qeexida saxiixa ee Burooyinka Phyllodes. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Burooyinka Phyllodes waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaanka kansarka iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa darteed cuntooyinka iyo kaabista qaar ayaa lagula taliyaa Burooyinka Phyllodes marka la qaadanayo daawaynta kansarka Carboplatin, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

MED12, SETD2, RARA, AHR iyo ALOX15 waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Burooyinka Phyllodes. MED12 waxaa lagu soo warramey 60.0 % bukaanada matala dhamaan tijaabooyinka kiliinikada. SETD2 waxaa lagu soo warramey 30.0 %. Isku darka xogta bukaanka ee dadweynaha ayaa daboolaya da'da 22 ilaa 79. 0.0 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Biology-ga Phyllodes Tumors oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha loogu talagalay Burooyinka Phyllodes

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro saytuun khudaar ah ama bocorka JAPAN?

Saytuun khudaareed waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Ferulic Acid, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Saytuun ayaa lagula talinayaa Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin. Tani waa sababtoo ah Saytuun waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Carboplatin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Japanese Pumpkin waa Quercetin, Ferulic Acid, Curcumin, Vitamin E, Beta-carotene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Bocorka Japan laguma talinayo Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarka mid adkaysi u leh ama aan ka jawaabin.

Saytuun khudaar ah ayaa lagula taliyaa bocorka JAPAN oo loogu talagalay Burooyinka Phyllodes iyo daawaynta Carboplatin.

Dooro khudaar khudaar ah ama PUMMELO?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Curcumin, Beta-carotene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Abrikot ayaa lagula talinayaa Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin. Tani waa sababta oo ah abrikot waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Carboplatin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira miro Pummelo waa Quercetin, Caffeine, Curcumin, Genistein, Apigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Pummelo laguma talinayo Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Khudaar FRUIT ayaa lagula talinayaa PUMMELO oo loogu talagalay Burooyinka Phyllodes iyo daawaynta Carboplatin.

Dooro Nut CASHEW NUT ama COLORADO PINYON?

Cashew Nut waxa ku jira waxyaabo badan oo firfircoon ama bioactives sida Quercetin, Curcumin, Beta-carotene, Gallic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Nut Cashew waxaa lagula talinayaa Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin. Tani waa sababtoo ah Cashew Nut waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Carboplatin.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Colorado Pinyon waa Caffeine, Curcumin, Genistein, Apigenin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair iyo kuwo kale. Colorado Pinyon laguma talinayo Burooyinka Phyllodes marka daawaynta kansarka ee socota ay tahay Carboplatin sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama ka jawaabi kara.

CASHEW NUT waxaa lagula talinayaa COLORADO PINYON oo loogu talagalay Burooyinka Phyllodes iyo daawaynta Carboplatin.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Burooyinka Phyllodes ama taariikhda qoysku waa "Maxaan Cunnaa si ka duwan sidii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro basbaaska duurjoogta ah ee khudradda ama basbaaska gambaleelka cas?

Leek duurjoogta ah waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Apigenin, Daidzein, Formononetin, Delphinidin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida NFKB Signaling, Calaamadaynta Asiidhka Retinoic, Calaamadaynta MAPK iyo Sababta Kobaca iyo kuwa kale. Leek duurjoogta ah waxaa lagula talinayaa halista Burooyinka Phyllodes marka khatarta hidde-sidaha la xiriirta ay tahay AHR. Tani waa sababta oo ah Wild Leek waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Cas Bell Pepper waa Curcumin, Daidzein, Formononetin, Quercetin, Linalool. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling and Growth Factor Signaling iyo kuwa kale. Basbaaska gaduudan laguma talinayo marka halista Burooyinka Phyllodes marka khatarta hidde-sidaha ay tahay AHR sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Leek duur-joogta khudaarta ah waxaa lagula taliyaa basbaaska casaanka ah ee halista kansarka.

Dooro midhaha cas raspberry ama lingonberry?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Ellagic Acid, Daidzein, Formononetin, Quercetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida RAS-RAF Signaling, Signaling MYC, Calaamadaynta MAPK iyo Calaamadaynta Sababta Kobaca iyo kuwa kale. Raspberry cas ayaa lagula talinayaa halista Burooyinka Phyllodes marka khatarta hidde-sidaha la xiriirta ay tahay AHR. Tani waa sababta oo ah Raspberry-ka Cas wuxuu kordhiyaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee miraha Lingonberry waa Curcumin, Daidzein, Formononetin, Quercetin, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Retinoic Acid Signaling, Isbaarada Wareegga Unugyada iyo P53 Signaling iyo kuwa kale. Lingonberry laguma talinayo marka khatarta ah Burooyinka Phyllodes marka khatarta hidde ee la xiriirta ay tahay AHR sababtoo ah waxay kordhisaa dariiqyada saxiixa.

Raspberry guduudan oo midho ah ayaa lagula talinayaa lingonberry si loo helo khatarta hidda-socodka ee AHR ee kansarka.

Dooro Nut COMMON HAZELNUT ama XARUNTA YURUB?

Hazelnut-ka caadiga ah waxa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Daidzein, Formononetin, Quercetin, Lycopene. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimiko oo kala duwan sida MYC Signaling, P53 Signaling, MAPK Signaling and Growth Signaling iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa khatarta Burooyinka Phyllodes marka khatarta hidde-sidaha la xiriirta ay tahay AHR. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut Yurub waa Curcumin, Apigenin, Ellagic Acid, Daidzein, Formononetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida TGFB Signaling iyo Oncogenic Histone Methylation iyo kuwa kale. Chestnut Yurub laguma talinayo marka khatarta ah Burooyinka Phyllodes marka khatarta hidde ee la xiriirta ay tahay AHR sababtoo ah waxay kordhisaa dariiqyada saxiixa.

HAZELNUT caam ah ayaa lagula taliyaa laabta Yurubta khatarta kansarka hidda-wadaha.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Burooyinka Phyllodes. Bukaannada Phyllodes Tumors iyo shakhsiyaadka leh khatarta hidde-sidaha waxay had iyo jeer qabaan su'aashan: "Waa maxay cuntooyinka iyo nafaqooyinka nafaqada ee lagu taliyey aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo tilmaamayaasha kansarka sida Phyllodes Tumors, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic oo dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Saytuun waxay ka kooban tahay tiro kala duwan oo noole noolayaal ah, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Burooyinka Phyllodes?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

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