Cuntooyinka loogu talagalay Histiocytosis!

Hordhac

Cuntooyinka loogu talagalay Histiocytosis waa in loo gaaryeelaa qof kasta oo waa in sidoo kale la qabsado marka daaweynta kansarka ama hidde-sidaha buradu ay isbeddelaan. Shakhsiyaynta iyo la qabsiga waa in ay tixgelisaa dhammaan maaddooyinka firfircoon ama bioactives ee ku jira cuntooyinka kala duwan marka loo eego bayooloojiyada unugyada kansarka, genetics, daawaynta, xaaladaha qaab nololeedka iyo doorbidka cuntada. Sidaa darteed iyadoo nafaqadu ay tahay mid ka mid ah go'aamada aadka muhiimka u ah bukaanka kansarka iyo qofka halista ugu jira kansarka inuu sameeyo - sida loo doorto cuntooyinka uu cuno maaha hawl fudud.

Histiocytosis waa koox naadir ah oo xanuuno ah oo lagu garto ururin aan caadi ahayn oo soo dhex gala tirooyin kala duwan oo unugyada difaaca sida monocytes, macrophages iyo unugyada dendritic ee unugyada ay saameeyeen. Mid ka mid ah nooc ka mid ah histiocytosis waa Langerhans cell histiocytosis (LCH), kaas oo inta badan saameeya carruurta iyo dadka waaweyn. Calaamadaha histiocytosis way kala duwanaan karaan iyadoo ku xiran nooca iyo xubnaha ku lug leh, laakiin sida caadiga ah waxaa ka mid ah lafo xanuun, finan maqaarka ah, iyo hawlgabka xubnaha. Bukaannada carruurta ee leh LCH-ka khatarta sare leh waxay leeyihiin ku dhawaad ​​90% fursadda badbaadada. Daaweynta histiocytosis caadi ahaan waxay ku lug leedahay habab kala duwan, oo ay ku jiraan kiimoterabiga, daaweynta shucaaca, iyo daawaynta la beegsaday. Go'aannada daawadu waxay ku salaysan yihiin nooca, goobta iyo inta uu cudurka yahay; xubnaha ku lug leh; arrimaha noolaha; hidde-sideyaasha cudurka iyo tiro badan oo arrimo kale ah. Tusaale ahaan, bukaanada qaba LCH-ka khatarta sare leh waa in ay helaan ugu yaraan 1 sano oo isku darka kemotherabi ah. Si kastaba ha noqotee, daawaynta ugu fiican ee LCH lama aasaasin waxaana lagu talinayaa in daawadu ay noqoto mid muxaafid ah oo ku xaddidan shakhsiyaadka leh calaamadaha dastuuriga ah sida xanuunka, qandhada, ku guuldareysiga inay koraan iyo khalkhalka xubnaha muhiimka ah, iyo sidoo kale kuwa halista ugu jira CNS (dhexda). habdhiska dareenka) ka qayb qaadashada.

Histiocytosis miyay muhiim u tahay waxa khudaarta, miraha, lawska, miraha uu qofku cuno?

Su'aasha nafaqeynta ee aadka u badan ee ay weydiiyaan bukaannada kansarka iyo shakhsiyaadka halista ugu jira hidde-sidaha kansarka waa - kansarrada sida Histiocytosis miyay khusaysaa cuntooyinka aan cuno iyo kuwa aanan samayn? Mise haddii aan raaco cunto ku salaysan geedka ma ku filan tahay kansarka sida Histiocytosis?

Tusaale ahaan miyay muhiim tahay haddii khudaarta Parsnip la isticmaalo in ka badan marka la barbar dhigo Kaabashka Napa? Miyay wax farqi ah samaynaysaa haddii khudaarta Pummelo laga doorbido liin? Sidoo kale haddii xulashooyin la mid ah loo sameeyo nuts/abuurka sida Black Walnut oo ka sarreeya Chestnut iyo garaacyada sida Chickpea oo ka sarreeya digirta caadiga ah. Oo haddii waxa aan cuno ay arrintu khusayso - markaa sidee qofku u aqoonsan karaa cuntooyinka lagu taliyay Histiocytosis oo ma isku mid baa jawaab u tahay qof kasta oo leh isla ogaanshaha ama khatarta hidde-sidaha?

Haa! Cuntooyinka aad cuntid waxay muhiim u yihiin Histiocytosis!

Talooyinka cuntadu waxay noqon karaan kuwo isku mid ah qof kasta oo way ka duwanaan karaan xitaa ogaanshaha isku midka ah iyo khatarta hidda-socodka.

Dhammaan cuntooyinka ( khudaarta, miraha, lawska, iniinaha, garaaca, saliidaha iwm.) iyo kaabayaasha nafaqadu waxay ka kooban yihiin wax ka badan hal walxo molecular ama bio-actives oo qiyaas iyo tiro kala duwan leh. Walax kasta oo firfircooni waxay leedahay hab u gaar ah oo wax qabad - kaas oo noqon kara firfircooni ama xannibaadda dariiqyada biochemical ee kala duwan. Cuntooyinka si fudud loo sheegay iyo kaabisyada lagu taliyay waa kuwa aan keenin korodhka wadayaasha molecular ee kansarka laakiin la yareeyo. Haddii kale cuntooyinkaas waa inaan lagu talin. Cuntooyinka waxaa ku jira maaddooyin badan oo firfircoon - markaa marka la qiimeynayo cuntooyinka iyo kaabayaasha waxaad u baahan tahay inaad tixgeliso saameynta dhammaan maaddooyinka firfircoon si wadajir ah halkii aad ka ahaan lahayd mid gaar ah.

Tusaale ahaan Pummelo waxa ku jira maaddooyinka firfircoon ee Lycopene, Protocatechuic Acid, Caffeine, Curcumin, Quercetin. Liin dhanaantu waxa ay ka kooban tahay maaddooyin firfircoon oo D-limonene, Linalool, Protocatechuic Acid, Caffeine, Curcumin iyo kuwo kale oo suurtogal ah.

Khalad caadi ah oo la sameeyo marka la go'aaminayo oo la dooranayo cuntooyinka la cuno Histiocytosis - waa in la qiimeeyo oo kaliya maaddooyinka firfircoon ee la doortay ee ku jira cuntooyinka oo la iska indhatiro inta kale. Sababtoo ah maaddooyinka kala duwan ee firfircoon ee ku jira cuntooyinka ayaa laga yaabaa inay saameyn iska soo horjeeda ku yeeshaan darawalada kansarka - ma qaadan kartid maaddooyinka firfircoon ee cuntooyinka iyo kaabayaasha si loo gaaro go'aanka nafaqada ee Histiocytosis.

HAA – DOORASHOOYINKA CUNTADA EE KANSARKA WAXAY U TAAGAN YAHAY. GO'AANKA NAFAQADA waa in ay tixgeliyaan dhammaan walxaha firfircoon ee CUNTADA.

Xirfadaha Loogu Baahan Yahay Nafaqaynta Shakhsiyaynta Histiocytosis?

Nafaqaynta shakhsi ahaaneed ee kansarrada sida Histiocytosis waxay ka kooban tahay cuntooyin/kaabyo lagu taliyey; Cuntooyinka aan lagu talin/kabka tusaale ahaan cunto karinta kuwaas oo mudnaanta siiya isticmaalka cuntooyinka lagu taliyay. Tusaale nafaqeynta gaarka ah ayaa tan lagu arki karaa link.

Go'aaminta cuntooyinka lagu taliyay iyo in kale waa mid aad u adag, waxay u baahan tahay khibrad ku saabsan bayoolajiga Histiocytosis, sayniska cuntada, genetics, biochemistry oo ay weheliso faham wanaagsan oo ku saabsan sida daawaynta kansarka u shaqeyso iyo baylahda la xidhiidha taas oo daawadu ay joojin karto waxtarka.

Khibradda UGU YAR EE AQOONTA EE LOO BAAHAN YAHAY NAFAQADA SHAQSIYADEEDKA KANSARKA WAA: NOLOLIGA KANSARKA, CUNTADA CUNTADA, DAAWAYNTA KANSARKA IYO HIDDAHA HIDDAHA.

Astaamaha kansarka sida Histiocytosis

Dhammaan kansarrada sida Histiocytosis waxaa lagu sifeyn karaa nooc gaar ah oo waddooyinka biochemical ah - dariiqooyinka saxiixa ee Histiocytosis. Dariiqooyin kiimikaad sida RAS-RAF Signaling, DNA Repair, MAPK Signaling, PI3K-AKT-MTOR Signaling waa qayb ka mid ah qeexida saxiixa Histiocytosis. Hidde-sideyaasha kansarku qof walba wuu ka duwanaan karaa sidaas darteed saxiixooda gaarka ah ee kansarku wuxuu noqon karaa mid gaar ah.

Daawaynta waxtarka u leh Histiocytosis waxay u baahan yihiin inay ogaadaan dariiqooyinka biochemical ee la xidhiidha saxeexa bukaanka kansarka iyo shakhsiga khatarta hidde-sidaha. Sidaa darteed daawayn kala duwan oo leh habab kala duwan oo ficil ah ayaa waxtar u leh bukaanada kala duwan. Si la mid ah iyo sababo la mid ah cuntooyinka iyo kaabista waxay u baahan yihiin in shaqsi kasta loo gaaryeelo. Sidaa awgeed cuntooyinka iyo kaabayaasha qaarkood ayaa lagula taliyaa Histiocytosis marka la qaadanayo daawaynta kansarka Shucaaca, iyo cuntooyinka qaar iyo kaabista laguma talinayo.

Ilaha sida cBioPortal iyo qaar kale oo badan ayaa bixiya xogta bukaan-socodka ee aan la magacaabin ee laga helay tijaabooyinka bukaan-socodka ee dhammaan calaamadaha kansarka. Xogtan waxay ka kooban tahay tafaasiisha daraasadda tijaabada caafimaad sida cabbirka saamiga / tirada bukaannada, kooxaha da'da, jinsiga, qowmiyadda, daawaynta, goobta burooyinka iyo isbeddellada hidde-sidaha.

AAF, F13A1, ADAMTS1, ACOT1 iyo PTEN waa hiddo-wadaha ugu sarreeya ee la soo sheegay ee Histiocytosis. ARAF waxa lagu soo warramey 16.7 % bukaanada mataleya dhamaan tijaabooyinka caafimaad. Iyo F13A1 ayaa lagu soo warramey 16.7 %. Isku darka xogta bukaan-socodka ee dadweynaha ayaa daboolaya da'da 37 ilaa 60. 70.8 % xogta bukaanka waxaa loo aqoonsaday inay yihiin rag. Bayoloji Histiocytosis oo ay weheliso hidde-sideyaasha la soo sheegay ayaa si wada jir ah u qeexaya dariiqooyinka biochemical ee saxeexa dadweynaha ee kansarkan. Haddii genetics-ka burada kansarka shakhsi ahaaneed ama hiddo-wadaha ka qaybqaata khatarta sidoo kale waa la yaqaan markaa waa in sidoo kale loo isticmaalo shakhsiyaynta nafaqada.

Dookhyada nafaqeynta waa in ay iswaafaqaan shaqsi walba saxiixiisa.

Cuntada iyo Kaabayaasha Histiocytosis

Bukaanka Kansarka

Bukaanjiifka kansarka ee ku jira daawaynta ama daryeelka palliative waxay u baahan yihiin inay go'aan ka gaadhaan cuntada iyo kaabista - kaloriinta cuntada ee loo baahan yahay, maaraynta waxyeellooyin kasta oo daawaynta iyo sidoo kale hagaajinta maaraynta kansarka. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo doorashada iyo kala horraysiinta cuntooyinka kuwaas oo shakhsi ahaan loo habeeyey oo loo habeeyey daawaynta kansarka ee socota waa muhiim oo dhib badan. Waa kuwan tusaalayaal siinaya tilmaamo lagu samaynayo go'aannada nafaqada.

Dooro PARSNIP khudaar ama kaabash NAPA?

Parsnip khudaarta waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Protocatechuic Acid, Curcumin, Quercetin, Lupeol, Gallic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Dayactirka DNA iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Parsnip ayaa lagula talinayaa Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Parsnip waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Napa Cabbage waa Protocatechuic Acid, Curcumin, Lupeol, Formononetin, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Kaabashka Napa laguma talinayo Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daaweynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Doofaarka khudaarta leh waxaa lagula talinayaa kaabajka NAPA ee Histiocytosis iyo shucaaca daawaynta.

Dooro Lemon ama PUMMELO?

Liin dhanaantu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives ah sida D-limonene, Linalool, Protocatechuic Acid, Caffeine, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Signaling MYC iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Liin dhanaan waxa lagula talinayaa Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Liintu waxay wax ka beddeshaa dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta Shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee khudradda Pummelo waa Lycopene, Protocatechuic Acid, Caffeine, Curcumin, Quercetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Pummelo laguma talin Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Liin dhanaan miraha waxaa lagula talinayaa PUMMELO oo loogu talagalay Histiocytosis iyo Shucaaca daawaynta.

Dooro Nut BLACK WALNUT ama LAABKA?

Walnut madow waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Protocatechuic Acid, Ellagic Acid, Curcumin, Myricetin, Quercetin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, Signaling MYC iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Walnut madow waxa lagula talinayaa Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac. Tani waa sababta oo ah Walnut Madow ayaa wax ka beddela dariiqyada biochemical ee si cilmiyeysan loo soo sheegay si loo dareemo saameynta shucaaca.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira Chestnut waa Lycopene, Protocatechuic Acid, Ellagic Acid, Caffeine, Curcumin. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida DNA Repair, MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Chestnut laguma talinayo Histiocytosis marka daawaynta kansarka ee socota ay tahay Shucaac sababtoo ah waxay wax ka beddeshaa dariiqyada biochemical ee ka dhigaya daawaynta kansarku mid adkaysi u leh ama aan ka jawaabin.

Walaska madow waxa lagula talinayaa laabta dusheeda Histiocytosis iyo shucaaca daawaynta.

Shakhsiyaadka leh Khatarta Hidde ee Kansarka

Su'aasha ay weydiiyaan shakhsiyaadka leh khatarta hidde-sidaha ee Histiocytosis ama taariikhda qoyska waa "Maxaan Cunnaa si ka duwan kii hore?" iyo sida ay tahay inay doortaan cuntooyinka iyo kaabista si loo maareeyo khatarta cudurka. Maadaama khatarta kansarku aanay jirin wax la qaban karo marka la eego daawaynta - go'aamada cuntooyinka iyo kaabista ayaa noqda mid muhiim ah iyo mid ka mid ah waxyaallaha aadka u yar ee la qaban karo. Dhammaan cuntooyinka dhirta ku salaysan maaha kuwo siman oo ku salaysan hidde-sidaha la aqoonsaday iyo saxeexa dariiqa - doorashooyinka cuntada iyo kaabista waa in la shakhsiyeeyo.

Dooro CAULIFLOWER ama AMERICAN PAKEWEED?

Cauliflower khudradda waxaa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Lupeol, Daidzein, Formononetin, Beta-sitosterol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, RAS-RAF Signaling, MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Cauliflower ayaa lagula talinayaa halista Histiocytosis marka khatarta hidde-sidaha la xiriirta ay tahay ACOT1. Tani waa sababta oo ah Cauliflower waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee ku jira khudradda Pokeweed American waa Apigenin, Curcumin, Quercetin, Lupeol, Caffeic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Kansarka Oncogenic Epigenetics iyo Complement Cascade iyo kuwa kale. Pokeweed American laguma talinayo marka halista Histiocytosis marka khatarta hidde-sidaha lala xiriiriyo ay tahay ACOT1 sababtoo ah waxay kordhisaa dariiqyada saxiixa.

ubaxa khudaarta leh waxaa lagula talinayaa PAKEweed AMERICA AH HALISTA HIDDEEDKA EE KANSARKA.

Dooro midhaha cas raspberry ama lingonberry?

Khudradu waxay ka kooban tahay waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Ellagic Acid, Quercetin, Lupeol, Daidzein. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, RAS-RAF Signaling, MYC Signaling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Raspberry cas ayaa lagula talinayaa halista Histiocytosis marka khatarta hidde-sidaha la xidhiidha ay tahay ACOT1. Tani waa sababta oo ah Raspberry-ka Cas wuxuu kordhiyaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxiixa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee miraha Lingonberry waa Curcumin, Quercetin, Lycopene, Lupeol, Resveratrol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida P53 Signaling iyo Complement Cascade iyo kuwa kale. Lingonberry laguma talinayo marka halista Histiocytosis marka khatarta hidde-sidaha lala xiriiriyo ay tahay ACOT1 sababtoo ah waxay kordhisaa dariiqooyinka saxiixa.

Raspberryry cas ee miraha waxaa lagula talinayaa lingonberry si loo helo ACOT1 Khatarta Hiddada ee Kansarka.

Dooro Nut COMMON HAZELNUT ama XARUNTA YURUB?

Hazelnut-ka caadiga ah waxa ku jira waxyaabo badan oo firfircoon ama bioactives sida Curcumin, Quercetin, Lycopene, Lupeol, Caffeic Acid. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida MAPK Signaling, RAS-RAF Signaling, Extracellular Matrix Remodeling iyo PI3K-AKT-MTOR Signaling iyo kuwa kale. Hazelnut-ka caadiga ah ayaa lagula taliyaa halista Histiocytosis marka khatarta hidde-sidaha la xiriirta ay tahay ACOT1. Tani waa sababta oo ah Hazelnut Common waxay kordhisaa dariiqyada biochemical ee ka soo horjeeda wadayaasha saxeexa.

Qaar ka mid ah maaddooyinka firfircoon ama bioactives ee Chestnut Yurub waa Apigenin, Curcumin, Ellagic Acid, Quercetin, Lupeol. Maaddooyinkan firfircooni waxay maamulaan dariiqooyin kiimikaad oo kala duwan sida Kansarka Oncogenic Epigenetics iyo Complement Cascade iyo kuwa kale. Chestnut Yurub laguma talinayo marka halista Histiocytosis marka khatarta hidde-sidaha la xidhiidha ay tahay ACOT1 sababtoo ah waxay kordhisaa dariiqyada saxeexa.

HAZELNUT caam ah ayaa lagula talinayaa laabta Yurub si loogula taliyo khatarta hidda-sidaha ACOT1 ee kansarka.

In Gabagabo

Cuntooyinka iyo Kaabayaasha la doortay ayaa ah go'aamo muhiim u ah kansarka sida Histiocytosis. Bukaanjiifka Histiocytosis iyo shakhsiyaadka leh khatarta hidde-sidaha had iyo jeer waxay qabaan su'aashan: "Waa maxay cuntooyinka iyo kaabisyada nafaqeynta ee lagu taliyay aniga iyo kuwa aan ahayn?" Waxaa jira aaminsanaan guud oo ah fikrad khaldan oo ah in dhammaan cuntooyinka dhirta ku salaysan ay faa'iido yeelan karaan ama aysan ahayn laakiin aan waxyeello lahayn. Cuntooyinka qaarkood iyo kaabisyada qaarkood waxay faragelin karaan daawaynta kansarka ama waxay kor u qaadi karaan wadayaasha dariiqyada molecular ee kansarka.

Waxaa jira noocyo kala duwan oo calaamado kansar ah sida Histiocytosis, mid kasta oo leh hidde-sidaha burooyinka kala duwan oo leh kala duwanaansho genomic dheeraad ah oo qof kasta ah. Intaa waxaa dheer daawaynta kansar kasta iyo kiimoterabi kasta waxay leeyihiin hab wax-qabad oo gaar ah. Cunto kasta sida Parsnip waxay ka kooban tahay noocyo kala duwan oo bioactives ah oo tirooyin kala duwan leh, kuwaas oo saameyn ku leh noocyo kala duwan oo kala duwan oo ah dariiqyada biochemical. Qeexida nafaqeynta shakhsi ahaaneed waa talooyinka cuntada ee gaarka ah ee tilmaamaya kansarka, daawaynta, genetics, qaab nololeedka iyo arrimo kale. Go'aannada shakhsiyaynta nafaqada ee kansarka waxay u baahan yihiin aqoonta bayoolajiga kansarka, sayniska cuntada iyo fahamka daaweynta kemotherabi ee kala duwan. Ugu dambeyntii marka ay jiraan isbeddel daaweyn ama genomics cusub ayaa la aqoonsaday - shakhsiyeynta nafaqeynta waxay u baahan tahay dib-u-qiimeyn.

Xalka shakhsiyaynta nafaqeynta ee addon ayaa ka dhigaysa go'aan qaadashada mid fudud oo meesha ka saaraysa dhammaan mala-awaalka ka jawaabaya su'aasha, "Cunto noocee ah ayaan dooran karaa ama ma dooran karaa Histiocytosis?". Kooxda edbinta badan ee addon waxaa ka mid ah dhakhaatiirta kansarka, saynisyahano caafimaad, injineerada software iyo saynisyahano xogta.

tixraacyada

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